2-(5-Methyl-1,3-thiazol-4-yl)ethanol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    38067-32-2

    Molecular formula
    C6H9NOS

    SMILES
    CC1=C(N=CS1)CCO

  • Odor profile

    Fragrance
    Nutty 74.79%
    Roasted 74.32%
    Meaty 71.86%
    Beefy 43.8%
    Fatty 43.33%
    Sulfurous 42.77%
    Savory 38.27%
    Cooked 38.22%
    Hazelnut 37.86%
    Popcorn 37.08%

     

    Flavor
    Fatty 48.62%
    Roasted 40.06%
    Nutty 36.33%
    Coffee 36.29%
    Vegetable 31.79%
    Bitter 30.71%
    Roast 29.98%
    Musty 29.36%
    Meaty 27.83%
    Burnt 27.35%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.0

    pKa est.
    6.57 (neutral)

    Molecular weight
    143.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    274°C

    Flash point

    • 105.67 ˚C est.

  • Synonyms

    • 38067-32-2
    • 2-(5-Methylthiazol-4-yl)ethanol
    • 2-(5-methyl-1,3-thiazol-4-yl)ethanol
    • NSC131817
    • SCHEMBL1792946
    • DTXSID20299651
    • LZIBYTYLWJTDFF-UHFFFAOYSA-N
    • AKOS023405804
    • 4-(2-hydroxy ethyl)-5-methylthiazole
    • NSC-131817
    • BS-17150
    • CS-0186431
    • C74944

  • Applications

    2-(5-Methyl-1,3-thiazol-4-yl)ethanol, CAS 38067-32-2, is principally used as an intermediate and building block for the synthesis of thiazole-containing compounds in pharmaceuticals and agrochemicals; it also serves as a precursor for diverse heterocyclic derivatives in specialty chemicals, cosmetics, coatings and inks; the hydroxyl group enables conversion to monomers or crosslinkers for polymers and coating matrices; in addition, it may be explored as a fragrance-related intermediate or for developing fragrance components, subject to regulatory and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 285.17
    methanol 457.34
    isopropanol 202.91
    water 52.87
    ethyl acetate 110.48
    n-propanol 213.12
    acetone 249.67
    n-butanol 164.73
    acetonitrile 154.41
    DMF 792.91
    toluene 60.12
    isobutanol 143.28
    1,4-dioxane 315.02
    methyl acetate 132.99
    THF 357.96
    2-butanone 156.2
    n-pentanol 111.97
    sec-butanol 142.09
    n-hexane 2.41
    ethylene glycol 267.86
    NMP 376.93
    cyclohexane 4.33
    DMSO 657.24
    n-butyl acetate 60.92
    n-octanol 61.86
    chloroform 285.03
    n-propyl acetate 59.98
    acetic acid 199.31
    dichloromethane 240.65
    cyclohexanone 206.12
    propylene glycol 198.46
    isopropyl acetate 64.49
    DMAc 410.07
    2-ethoxyethanol 255.51
    isopentanol 107.74
    n-heptane 5.9
    ethyl formate 114.33
    1,2-dichloroethane 150.91
    n-hexanol 112.53
    2-methoxyethanol 470.04
    isobutyl acetate 47.77
    tetrachloromethane 62.45
    n-pentyl acetate 55.64
    transcutol 280.2
    n-heptanol 66.17
    ethylbenzene 24.82
    MIBK 79.98
    2-propoxyethanol 242.77
    tert-butanol 188.59
    MTBE 84.58
    2-butoxyethanol 138.39
    propionic acid 148.64
    o-xylene 44.7
    formic acid 217.73
    diethyl ether 82.5
    m-xylene 49.62
    p-xylene 35.66
    chlorobenzene 91.38
    dimethyl carbonate 76.48
    n-octane 3.63
    formamide 234.72
    cyclopentanone 282.51
    2-pentanone 123.31
    anisole 93.43
    cyclopentyl methyl ether 122.96
    gamma-butyrolactone 273.22
    1-methoxy-2-propanol 298.77
    pyridine 176.4
    3-pentanone 91.3
    furfural 305.13
    n-dodecane 4.41
    diethylene glycol 315.12
    diisopropyl ether 23.76
    tert-amyl alcohol 132.63
    acetylacetone 154.97
    n-hexadecane 4.97
    acetophenone 92.26
    methyl propionate 112.55
    isopentyl acetate 56.55
    trichloroethylene 272.85
    n-nonanol 53.8
    cyclohexanol 113.42
    benzyl alcohol 104.59
    2-ethylhexanol 56.62
    isooctanol 53.17
    dipropyl ether 46.67
    1,2-dichlorobenzene 87.9
    ethyl lactate 65.87
    propylene carbonate 127.85
    n-methylformamide 332.14
    2-pentanol 90.21
    n-pentane 3.76
    1-propoxy-2-propanol 140.81
    1-methoxy-2-propyl acetate 93.93
    2-(2-methoxypropoxy) propanol 105.85
    mesitylene 32.62
    ε-caprolactone 143.84
    p-cymene 27.58
    epichlorohydrin 273.12
    1,1,1-trichloroethane 145.98
    2-aminoethanol 302.57
    morpholine-4-carbaldehyde 383.01
    sulfolane 372.81
    2,2,4-trimethylpentane 5.66
    2-methyltetrahydrofuran 183.29
    n-hexyl acetate 68.93
    isooctane 4.91
    2-(2-butoxyethoxy)ethanol 143.54
    sec-butyl acetate 42.1
    tert-butyl acetate 74.93
    decalin 5.89
    glycerin 343.12
    diglyme 235.98
    acrylic acid 158.53
    isopropyl myristate 33.23
    n-butyric acid 150.36
    acetyl acetate 67.66
    di(2-ethylhexyl) phthalate 44.73
    ethyl propionate 56.41
    nitromethane 303.98
    1,2-diethoxyethane 81.38
    benzonitrile 110.82
    trioctyl phosphate 34.88
    1-bromopropane 68.77
    gamma-valerolactone 352.96
    n-decanol 41.06
    triethyl phosphate 37.51
    4-methyl-2-pentanol 54.86
    propionitrile 120.88
    vinylene carbonate 141.83
    1,1,2-trichlorotrifluoroethane 271.94
    DMS 62.78
    cumene 24.08
    2-octanol 45.3
    2-hexanone 74.23
    octyl acetate 45.08
    limonene 38.48
    1,2-dimethoxyethane 263.38
    ethyl orthosilicate 36.24
    tributyl phosphate 34.41
    diacetone alcohol 135.98
    N,N-dimethylaniline 73.28
    acrylonitrile 165.21
    aniline 116.68
    1,3-propanediol 286.73
    bromobenzene 78.63
    dibromomethane 138.56
    1,1,2,2-tetrachloroethane 208.85
    2-methyl-cyclohexyl acetate 51.3
    tetrabutyl urea 51.69
    diisobutyl methanol 36.59
    2-phenylethanol 93.27
    styrene 33.54
    dioctyl adipate 46.37
    dimethyl sulfate 162.7
    ethyl butyrate 49.02
    methyl lactate 127.52
    butyl lactate 62.15
    diethyl carbonate 37.37
    propanediol butyl ether 120.45
    triethyl orthoformate 42.27
    p-tert-butyltoluene 29.4
    methyl 4-tert-butylbenzoate 91.55
    morpholine 303.53
    tert-butylamine 93.53
    n-dodecanol 32.16
    dimethoxymethane 271.43
    ethylene carbonate 106.81
    cyrene 135.02
    2-ethoxyethyl acetate 79.14
    2-ethylhexyl acetate 45.41
    1,2,4-trichlorobenzene 109.1
    4-methylpyridine 173.77
    dibutyl ether 35.49
    2,6-dimethyl-4-heptanol 36.59
    DEF 163.7
    dimethyl isosorbide 144.89
    tetrachloroethylene 153.56
    eugenol 108.23
    triacetin 69.04
    span 80 95.18
    1,4-butanediol 150.17
    1,1-dichloroethane 154.93
    2-methyl-1-pentanol 82.83
    methyl formate 238.07
    2-methyl-1-butanol 107.82
    n-decane 6.37
    butyronitrile 112.42
    3,7-dimethyl-1-octanol 51.44
    1-chlorooctane 30.74
    1-chlorotetradecane 13.64
    n-nonane 5.57
    undecane 5.15
    tert-butylcyclohexane 7.07
    cyclooctane 2.72
    cyclopentanol 151.22
    tetrahydropyran 155.17
    tert-amyl methyl ether 66.9
    2,5,8-trioxanonane 176.82
    1-hexene 15.25
    2-isopropoxyethanol 151.18
    2,2,2-trifluoroethanol 133.03
    methyl butyrate 75.77

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction