2-(2-Phenoxyethoxy)ethanol

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  • Identifiers

    CAS number
    104-68-7

    Molecular formula
    C10H14O3

    SMILES
    C1=CC=C(C=C1)OCCOCCO

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Rose 50.29%
    Floral 49.35%
    Fresh 36.05%
    Balsamic 35.71%
    Sweet 27.07%
    Honey 26.74%
    Hyacinth 23.65%
    Odorless 23.03%
    Clean 22.57%
    Animal 21.66%

     

    Flavor
    Sweet 62.25%
    Floral 47.99%
    Bitter 45.57%
    Rose 41.54%
    Fruity 36.94%
    Musty 33.87%
    Honey 33.73%
    Balsam 32.61%
    Hyacinth 31.39%
    Chocolate 29.8%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.0

    pKa est.
    6.18 (neutral)

    Molecular weight
    182.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    304°C

    Flash point

    • 148.54 ˚C est.
    • 167 °C

  • Synonyms

    • 2-(2-Phenoxyethoxy)ethanol
    • 104-68-7
    • Diethylene glycol monophenyl ether
    • Phenyl carbitol
    • ETHANOL, 2-(2-PHENOXYETHOXY)-
    • Phenoxydiglycol
    • 2-(2-phenoxyethoxy)ethan-1-ol
    • Diethylene glycol phenyl ether
    • Ethanol,2-(2-phenoxyethoxy)-
    • Fenylkarbitol
    • Diethylene glycolphenyl ether
    • MFCD00045989
    • LZU6ET206Z
    • diethyleneglycol monophenyl ether
    • NSC-406593
    • Fenylkarbitol [Czech]
    • EINECS 203-227-5
    • UNII-LZU6ET206Z
    • NSC 406593
    • BRN 2093125
    • phenyl diglycol
    • AI3-04321
    • PHENYL DI GLYCOL
    • EC 203-227-5
    • WLN: Q2O2OR
    • SCHEMBL24035
    • SCHEMBL768675
    • SCHEMBL4459038
    • SCHEMBL5668019
    • DTXSID0051528
    • SCHEMBL11352154
    • MSK169610
    • NSC406593
    • AKOS008145660
    • FP44510
    • AS-41733
    • SY053473
    • DB-275762
    • CS-0217586
    • D5139
    • NS00004766
    • EN300-78435
    • W-109056
    • Q27283278
    • Z756092452
    • 104-68-7

  • Applications

    2-(2-Phenoxyethoxy)ethanol (CAS 104-68-7) is used as a solvent and humectant in cosmetics and personal care, helping dissolve and solubilize fragrance ingredients and actives while maintaining moisture. It also serves as an intermediate and polyol precursor in the production of polyurethanes and other polymer systems based on glycol ethers, enabling flexible, resilient materials. In coatings, inks, and adhesives, it functions as a plasticizer and processing aid, improving flow, leveling, and compatibility with formulation components. Additionally, it can be used as a co-solvent in industrial cleaners and detergents. In the fragrance industry, it may act as a solvent carrier for fragrance oils to enhance solubility and stability of aroma compounds.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 383.57
    methanol 614.68
    isopropanol 177.32
    water 4.48
    ethyl acetate 244.16
    n-propanol 221.05
    acetone 236.14
    n-butanol 158.32
    acetonitrile 274.05
    DMF 259.04
    toluene 37.8
    isobutanol 116.33
    1,4-dioxane 512.22
    methyl acetate 194.51
    THF 369.05
    2-butanone 128.47
    n-pentanol 113.52
    sec-butanol 127.35
    n-hexane 9.25
    ethylene glycol 264.38
    NMP 139.18
    cyclohexane 34.2
    DMSO 1390.3
    n-butyl acetate 96.23
    n-octanol 37.77
    chloroform 427.24
    n-propyl acetate 104.72
    acetic acid 663.21
    dichloromethane 552.11
    cyclohexanone 162.09
    propylene glycol 213.54
    isopropyl acetate 83.57
    DMAc 249.28
    2-ethoxyethanol 380.95
    isopentanol 103.01
    n-heptane 14.05
    ethyl formate 130.88
    1,2-dichloroethane 392.29
    n-hexanol 85.62
    2-methoxyethanol 617.35
    isobutyl acetate 59.82
    tetrachloromethane 41.99
    n-pentyl acetate 40.22
    transcutol 865.11
    n-heptanol 31.8
    ethylbenzene 20.57
    MIBK 58.86
    2-propoxyethanol 207.81
    tert-butanol 221.82
    MTBE 110.26
    2-butoxyethanol 95.66
    propionic acid 231.45
    o-xylene 32.02
    formic acid 372.05
    diethyl ether 202.01
    m-xylene 26.49
    p-xylene 27.0
    chlorobenzene 71.38
    dimethyl carbonate 68.98
    n-octane 5.17
    formamide 449.27
    cyclopentanone 172.47
    2-pentanone 90.56
    anisole 80.2
    cyclopentyl methyl ether 123.99
    gamma-butyrolactone 258.07
    1-methoxy-2-propanol 272.57
    pyridine 234.53
    3-pentanone 84.2
    furfural 270.14
    n-dodecane 5.0
    diethylene glycol 304.84
    diisopropyl ether 33.77
    tert-amyl alcohol 133.81
    acetylacetone 149.47
    n-hexadecane 5.46
    acetophenone 76.94
    methyl propionate 143.35
    isopentyl acetate 74.85
    trichloroethylene 493.17
    n-nonanol 36.72
    cyclohexanol 129.87
    benzyl alcohol 82.59
    2-ethylhexanol 48.56
    isooctanol 27.63
    dipropyl ether 84.96
    1,2-dichlorobenzene 75.83
    ethyl lactate 81.69
    propylene carbonate 132.27
    n-methylformamide 203.61
    2-pentanol 83.31
    n-pentane 11.53
    1-propoxy-2-propanol 138.7
    1-methoxy-2-propyl acetate 109.58
    2-(2-methoxypropoxy) propanol 133.91
    mesitylene 21.99
    ε-caprolactone 160.99
    p-cymene 22.45
    epichlorohydrin 357.81
    1,1,1-trichloroethane 160.27
    2-aminoethanol 315.89
    morpholine-4-carbaldehyde 293.39
    sulfolane 337.7
    2,2,4-trimethylpentane 7.88
    2-methyltetrahydrofuran 194.43
    n-hexyl acetate 62.4
    isooctane 5.26
    2-(2-butoxyethoxy)ethanol 178.45
    sec-butyl acetate 57.9
    tert-butyl acetate 82.88
    decalin 11.0
    glycerin 347.88
    diglyme 379.42
    acrylic acid 217.08
    isopropyl myristate 32.23
    n-butyric acid 240.23
    acetyl acetate 153.54
    di(2-ethylhexyl) phthalate 36.55
    ethyl propionate 92.73
    nitromethane 731.71
    1,2-diethoxyethane 188.53
    benzonitrile 78.83
    trioctyl phosphate 24.54
    1-bromopropane 143.66
    gamma-valerolactone 251.95
    n-decanol 28.1
    triethyl phosphate 59.8
    4-methyl-2-pentanol 40.0
    propionitrile 157.9
    vinylene carbonate 132.83
    1,1,2-trichlorotrifluoroethane 360.75
    DMS 83.97
    cumene 18.86
    2-octanol 19.76
    2-hexanone 78.54
    octyl acetate 38.66
    limonene 36.77
    1,2-dimethoxyethane 423.41
    ethyl orthosilicate 56.26
    tributyl phosphate 38.09
    diacetone alcohol 109.1
    N,N-dimethylaniline 53.98
    acrylonitrile 187.29
    aniline 90.21
    1,3-propanediol 330.33
    bromobenzene 66.16
    dibromomethane 307.5
    1,1,2,2-tetrachloroethane 400.58
    2-methyl-cyclohexyl acetate 65.66
    tetrabutyl urea 50.26
    diisobutyl methanol 33.59
    2-phenylethanol 61.25
    styrene 30.37
    dioctyl adipate 65.45
    dimethyl sulfate 129.99
    ethyl butyrate 91.53
    methyl lactate 107.8
    butyl lactate 50.96
    diethyl carbonate 80.2
    propanediol butyl ether 98.58
    triethyl orthoformate 80.42
    p-tert-butyltoluene 21.85
    methyl 4-tert-butylbenzoate 70.55
    morpholine 519.78
    tert-butylamine 107.97
    n-dodecanol 23.28
    dimethoxymethane 245.49
    ethylene carbonate 118.49
    cyrene 111.37
    2-ethoxyethyl acetate 81.02
    2-ethylhexyl acetate 57.85
    1,2,4-trichlorobenzene 93.23
    4-methylpyridine 108.35
    dibutyl ether 62.38
    2,6-dimethyl-4-heptanol 33.59
    DEF 148.63
    dimethyl isosorbide 177.85
    tetrachloroethylene 265.72
    eugenol 81.93
    triacetin 107.91
    span 80 97.09
    1,4-butanediol 143.07
    1,1-dichloroethane 207.7
    2-methyl-1-pentanol 80.52
    methyl formate 156.13
    2-methyl-1-butanol 96.91
    n-decane 7.84
    butyronitrile 128.86
    3,7-dimethyl-1-octanol 41.76
    1-chlorooctane 26.43
    1-chlorotetradecane 12.52
    n-nonane 7.34
    undecane 5.96
    tert-butylcyclohexane 8.98
    cyclooctane 10.27
    cyclopentanol 120.93
    tetrahydropyran 301.92
    tert-amyl methyl ether 77.57
    2,5,8-trioxanonane 282.9
    1-hexene 32.96
    2-isopropoxyethanol 184.46
    2,2,2-trifluoroethanol 192.88
    methyl butyrate 115.99

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction