2-(2-Octoxyethoxy)acetic acid

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  • Identifiers

    CAS number
    53563-70-5

    Molecular formula
    C12H24O4

    SMILES
    CCCCCCCCOCCOCC(=O)O

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fruity 43.14%
    Sweet 41.95%
    Oily 41.08%
    Fresh 41.03%
    Fatty 39.42%
    Waxy 34.12%
    Citrus 29.57%
    Green 27.53%
    Buttery 26.05%
    Peach 25.67%

     

    Flavor
    Fatty 47.92%
    Waxy 44.23%
    Oily 38.81%
    Cheese 34.33%
    Green 32.99%
    Mushroom 32.23%
    Fruity 30.53%
    Sweet 29.72%
    Creamy 29.15%
    Vegetable 27.59%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.9

    pKa est.
    5.6 (weak acid)

    Molecular weight
    232.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    322°C

    Flash point

    • 160.92 ˚C est.

  • Synonyms

    • 53563-70-5
    • SCHEMBL18140628
    • ICDFAVDDYZOXIU-UHFFFAOYSA-N
    • H55021
    • 53563-70-5

  • Applications

    2-(2-Octoxyethoxy)acetic acid (CAS 53563-70-5) is a glycol ether–type carboxylic acid that is commonly used as a solvent and surfactant precursor in industrial formulations; it can function as a co-solvent in coatings, inks, and cleaning products. It is often employed as an intermediate to synthesize other glycol ether derivatives, enabling the production of specialty surfactants and plasticizers for polymers. In cosmetics and personal care, it may serve as a solvent or emulsifier component in formulations, while in household products it can act as a surfactant/co-solvent that enhances cleaning performance. In polymer and coatings applications, it can act as a processing aid, dispersant, or stabilizer to improve dispersion and processability of resins and formulations. Overall, its use is usually formulation-specific and subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 537.01
    methanol 1137.1
    isopropanol 277.2
    water 0.63
    ethyl acetate 180.79
    n-propanol 329.18
    acetone 356.62
    n-butanol 246.08
    acetonitrile 100.54
    DMF 521.19
    toluene 35.86
    isobutanol 229.32
    1,4-dioxane 236.19
    methyl acetate 125.39
    THF 547.01
    2-butanone 169.73
    n-pentanol 197.91
    sec-butanol 198.19
    n-hexane 12.87
    ethylene glycol 123.64
    NMP 489.62
    cyclohexane 30.78
    DMSO 2069.41
    n-butyl acetate 172.52
    n-octanol 62.03
    chloroform 249.13
    n-propyl acetate 181.57
    acetic acid 508.1
    dichloromethane 303.58
    cyclohexanone 442.33
    propylene glycol 192.78
    isopropyl acetate 141.69
    DMAc 375.07
    2-ethoxyethanol 397.37
    isopentanol 213.68
    n-heptane 10.48
    ethyl formate 129.81
    1,2-dichloroethane 287.32
    n-hexanol 152.46
    2-methoxyethanol 655.01
    isobutyl acetate 118.76
    tetrachloromethane 47.93
    n-pentyl acetate 114.79
    transcutol 1030.88
    n-heptanol 66.06
    ethylbenzene 30.88
    MIBK 157.37
    2-propoxyethanol 301.54
    tert-butanol 367.11
    MTBE 137.18
    2-butoxyethanol 176.43
    propionic acid 255.26
    o-xylene 48.91
    formic acid 268.64
    diethyl ether 116.47
    m-xylene 49.9
    p-xylene 43.57
    chlorobenzene 71.4
    dimethyl carbonate 54.65
    n-octane 4.84
    formamide 342.87
    cyclopentanone 446.88
    2-pentanone 203.6
    anisole 80.07
    cyclopentyl methyl ether 242.97
    gamma-butyrolactone 474.71
    1-methoxy-2-propanol 446.83
    pyridine 164.93
    3-pentanone 122.54
    furfural 387.91
    n-dodecane 3.69
    diethylene glycol 280.55
    diisopropyl ether 42.74
    tert-amyl alcohol 243.46
    acetylacetone 279.06
    n-hexadecane 4.25
    acetophenone 126.96
    methyl propionate 142.37
    isopentyl acetate 159.77
    trichloroethylene 427.31
    n-nonanol 55.6
    cyclohexanol 272.67
    benzyl alcohol 114.38
    2-ethylhexanol 89.26
    isooctanol 62.0
    dipropyl ether 88.8
    1,2-dichlorobenzene 92.91
    ethyl lactate 117.63
    propylene carbonate 240.1
    n-methylformamide 280.54
    2-pentanol 143.57
    n-pentane 9.62
    1-propoxy-2-propanol 242.68
    1-methoxy-2-propyl acetate 195.78
    2-(2-methoxypropoxy) propanol 178.57
    mesitylene 43.31
    ε-caprolactone 332.28
    p-cymene 35.87
    epichlorohydrin 457.36
    1,1,1-trichloroethane 163.4
    2-aminoethanol 296.28
    morpholine-4-carbaldehyde 413.56
    sulfolane 888.59
    2,2,4-trimethylpentane 10.45
    2-methyltetrahydrofuran 304.92
    n-hexyl acetate 139.31
    isooctane 7.93
    2-(2-butoxyethoxy)ethanol 259.16
    sec-butyl acetate 113.75
    tert-butyl acetate 200.85
    decalin 15.36
    glycerin 274.77
    diglyme 493.94
    acrylic acid 194.37
    isopropyl myristate 49.51
    n-butyric acid 393.36
    acetyl acetate 131.82
    di(2-ethylhexyl) phthalate 62.32
    ethyl propionate 132.49
    nitromethane 540.56
    1,2-diethoxyethane 195.14
    benzonitrile 103.32
    trioctyl phosphate 47.51
    1-bromopropane 105.4
    gamma-valerolactone 573.07
    n-decanol 38.73
    triethyl phosphate 74.73
    4-methyl-2-pentanol 83.72
    propionitrile 99.47
    vinylene carbonate 189.07
    1,1,2-trichlorotrifluoroethane 479.92
    DMS 111.32
    cumene 32.22
    2-octanol 45.06
    2-hexanone 164.19
    octyl acetate 63.46
    limonene 61.43
    1,2-dimethoxyethane 424.92
    ethyl orthosilicate 74.41
    tributyl phosphate 65.27
    diacetone alcohol 279.48
    N,N-dimethylaniline 74.95
    acrylonitrile 135.77
    aniline 87.4
    1,3-propanediol 390.86
    bromobenzene 69.27
    dibromomethane 187.97
    1,1,2,2-tetrachloroethane 418.38
    2-methyl-cyclohexyl acetate 124.08
    tetrabutyl urea 90.31
    diisobutyl methanol 58.26
    2-phenylethanol 103.28
    styrene 34.68
    dioctyl adipate 100.15
    dimethyl sulfate 158.57
    ethyl butyrate 128.84
    methyl lactate 131.59
    butyl lactate 136.85
    diethyl carbonate 81.32
    propanediol butyl ether 199.19
    triethyl orthoformate 100.05
    p-tert-butyltoluene 35.86
    methyl 4-tert-butylbenzoate 135.66
    morpholine 417.93
    tert-butylamine 159.28
    n-dodecanol 28.38
    dimethoxymethane 264.0
    ethylene carbonate 168.91
    cyrene 191.64
    2-ethoxyethyl acetate 163.95
    2-ethylhexyl acetate 114.25
    1,2,4-trichlorobenzene 117.78
    4-methylpyridine 143.58
    dibutyl ether 77.58
    2,6-dimethyl-4-heptanol 58.26
    DEF 259.13
    dimethyl isosorbide 300.77
    tetrachloroethylene 286.32
    eugenol 130.6
    triacetin 195.53
    span 80 167.35
    1,4-butanediol 166.28
    1,1-dichloroethane 163.11
    2-methyl-1-pentanol 155.13
    methyl formate 158.03
    2-methyl-1-butanol 191.61
    n-decane 6.7
    butyronitrile 119.51
    3,7-dimethyl-1-octanol 72.37
    1-chlorooctane 36.49
    1-chlorotetradecane 13.12
    n-nonane 6.53
    undecane 4.64
    tert-butylcyclohexane 12.7
    cyclooctane 9.74
    cyclopentanol 289.62
    tetrahydropyran 289.67
    tert-amyl methyl ether 113.52
    2,5,8-trioxanonane 324.19
    1-hexene 44.53
    2-isopropoxyethanol 247.99
    2,2,2-trifluoroethanol 152.32
    methyl butyrate 210.32

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction