2-(2-Hydroxypropoxy)propan-1-ol

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  • Identifiers

    CAS number
    25322-69-4

    Molecular formula
    C6H14O3

    SMILES
    CC(CO)OCC(C)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 43.92%
    Fruity 39.43%
    Alcoholic 38.76%
    Buttery 34.61%
    Ethereal 28.68%
    Sweet 25.8%
    Oily 21.3%
    Solvent 20.68%
    Caramellic 20.6%
    Milky 20.51%

     

    Flavor
    Odorless 47.38%
    Fruity 40.59%
    Alcoholic 35.27%
    Creamy 33.16%
    Onion 32.5%
    Buttery 32.41%
    Fruit 30.46%
    Bitter 29.93%
    Musty 28.12%
    Very slight 26.13%

     

    Odor impact est.
    Low

    Odor threshold

    • 340 ppm

  • Properties

    XLogP3-AA
    -0.7

    pKa est.
    7.75 (neutral)

    Molecular weight
    134.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    225°C

    Melting point expt.

    • -58 °F (USCG, 1999)

    Flash point

    • 113.11 ˚C est.
    • 390 to 495 °F (USCG, 1999)
    • Flash Point varies from 390 to 495 °F, depending on molecular weight

    Solubility expt.

    • Lower molecular weight members are sol in water
    • Infinite
    • In water: PPG 425, >10,000 mg/L; PPG 1000, >1,000 mg/L; PPG 2000, 250 mg/L; PPG 2700, 15 mg/L

  • Synonyms

    • 2-(2-hydroxypropoxy)propan-1-ol
    • 2-(2-HYDROXYPROPOXY)-1-PROPANOL
    • 25322-69-4
    • 106-62-7
    • 1-Propanol, 2-(2-hydroxypropoxy)-
    • 2-(2-Hydroxypropoxy)propanol
    • WNY0H4G53Q
    • EINECS 203-416-2
    • DTXSID30861722
    • Emkapyl
    • Lineartop E
    • Niax ppg
    • Desmophen 360C
    • Poly[oxy(methyl-1,2-ethanediyl)], a-hydro-w-hydroxy-
    • Niax ppg 425
    • Jeffox PPG 400
    • Voranol P 1010
    • Laprol 2002
    • Niax ppg 1025
    • Niax ppg 3025
    • Napter E 8075
    • Laprol 702
    • UNII-WNY0H4G53Q
    • PPG?
    • PPG-3
    • SCHEMBL15111
    • CHEBI:53262
    • DTXCID20810608
    • CHEBI:179442
    • AKOS015899603
    • Dipropylene glycol(mixture of isomers)
    • BS-23535
    • NS00008462
    • F71159
    • Q26863457
    • 203-416-2

  • Applications

    2-(2-Hydroxypropoxy)propan-1-ol is a versatile solvent and chemical intermediate used in various industrial formulations. It serves as a processing aid and can act as a plasticizer or reactive diluent in coatings, inks, and polymer systems, notably polyurethanes and epoxy resins. It can function as a humectant and solvent in cosmetics and personal care products. It provides a building block for the synthesis of polyol polyethers and related surfactants and specialty chemicals. It is used in cleaning formulations and degreasers for industrial and household applications, and may be evaluated for use in electronics cleaning or as a processing aid in adhesives.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 280.09
    methanol 596.57
    isopropanol 165.16
    water 184.01
    ethyl acetate 21.62
    n-propanol 185.72
    acetone 53.1
    n-butanol 133.48
    acetonitrile 49.27
    DMF 292.44
    toluene 4.34
    isobutanol 111.66
    1,4-dioxane 139.99
    methyl acetate 33.69
    THF 133.13
    2-butanone 34.12
    n-pentanol 67.37
    sec-butanol 112.18
    n-hexane 3.11
    ethylene glycol 369.2
    NMP 234.19
    cyclohexane 7.46
    DMSO 411.82
    n-butyl acetate 21.44
    n-octanol 40.56
    chloroform 52.61
    n-propyl acetate 19.21
    acetic acid 364.09
    dichloromethane 58.97
    cyclohexanone 81.09
    propylene glycol 314.78
    isopropyl acetate 13.18
    DMAc 209.66
    2-ethoxyethanol 172.45
    isopentanol 69.76
    n-heptane 7.03
    ethyl formate 50.13
    1,2-dichloroethane 29.94
    n-hexanol 68.19
    2-methoxyethanol 364.3
    isobutyl acetate 13.96
    tetrachloromethane 11.76
    n-pentyl acetate 18.09
    transcutol 202.26
    n-heptanol 41.69
    ethylbenzene 5.35
    MIBK 15.86
    2-propoxyethanol 140.71
    tert-butanol 146.09
    MTBE 33.99
    2-butoxyethanol 84.65
    propionic acid 169.17
    o-xylene 9.15
    formic acid 385.19
    diethyl ether 22.08
    m-xylene 6.43
    p-xylene 7.93
    chlorobenzene 11.44
    dimethyl carbonate 16.3
    n-octane 2.84
    formamide 232.86
    cyclopentanone 96.29
    2-pentanone 22.71
    anisole 21.6
    cyclopentyl methyl ether 40.25
    gamma-butyrolactone 129.96
    1-methoxy-2-propanol 183.35
    pyridine 42.15
    3-pentanone 17.81
    furfural 147.92
    n-dodecane 2.71
    diethylene glycol 218.57
    diisopropyl ether 7.0
    tert-amyl alcohol 105.38
    acetylacetone 29.07
    n-hexadecane 2.86
    acetophenone 27.47
    methyl propionate 28.8
    isopentyl acetate 21.61
    trichloroethylene 52.85
    n-nonanol 33.9
    cyclohexanol 95.45
    benzyl alcohol 41.9
    2-ethylhexanol 34.52
    isooctanol 31.19
    dipropyl ether 24.1
    1,2-dichlorobenzene 15.32
    ethyl lactate 41.83
    propylene carbonate 67.45
    n-methylformamide 181.38
    2-pentanol 51.44
    n-pentane 3.97
    1-propoxy-2-propanol 93.88
    1-methoxy-2-propyl acetate 33.42
    2-(2-methoxypropoxy) propanol 85.86
    mesitylene 6.57
    ε-caprolactone 81.13
    p-cymene 10.88
    epichlorohydrin 92.02
    1,1,1-trichloroethane 17.75
    2-aminoethanol 389.84
    morpholine-4-carbaldehyde 241.71
    sulfolane 211.32
    2,2,4-trimethylpentane 4.05
    2-methyltetrahydrofuran 74.87
    n-hexyl acetate 31.22
    isooctane 2.56
    2-(2-butoxyethoxy)ethanol 99.54
    sec-butyl acetate 11.8
    tert-butyl acetate 18.06
    decalin 4.33
    glycerin 454.71
    diglyme 159.5
    acrylic acid 186.12
    isopropyl myristate 16.0
    n-butyric acid 121.1
    acetyl acetate 18.1
    di(2-ethylhexyl) phthalate 29.05
    ethyl propionate 17.76
    nitromethane 189.93
    1,2-diethoxyethane 31.56
    benzonitrile 29.54
    trioctyl phosphate 23.96
    1-bromopropane 15.13
    gamma-valerolactone 161.26
    n-decanol 25.54
    triethyl phosphate 21.95
    4-methyl-2-pentanol 26.02
    propionitrile 40.56
    vinylene carbonate 69.06
    1,1,2-trichlorotrifluoroethane 178.22
    DMS 24.28
    cumene 7.17
    2-octanol 22.86
    2-hexanone 19.68
    octyl acetate 22.94
    limonene 17.39
    1,2-dimethoxyethane 151.28
    ethyl orthosilicate 21.46
    tributyl phosphate 23.25
    diacetone alcohol 52.85
    N,N-dimethylaniline 24.55
    acrylonitrile 60.94
    aniline 26.99
    1,3-propanediol 320.56
    bromobenzene 7.92
    dibromomethane 32.69
    1,1,2,2-tetrachloroethane 53.64
    2-methyl-cyclohexyl acetate 29.9
    tetrabutyl urea 35.38
    diisobutyl methanol 20.66
    2-phenylethanol 35.72
    styrene 5.96
    dioctyl adipate 32.7
    dimethyl sulfate 45.6
    ethyl butyrate 22.28
    methyl lactate 67.97
    butyl lactate 38.24
    diethyl carbonate 17.73
    propanediol butyl ether 108.11
    triethyl orthoformate 25.62
    p-tert-butyltoluene 11.28
    methyl 4-tert-butylbenzoate 44.75
    morpholine 184.66
    tert-butylamine 69.02
    n-dodecanol 20.21
    dimethoxymethane 73.33
    ethylene carbonate 52.16
    cyrene 94.42
    2-ethoxyethyl acetate 26.31
    2-ethylhexyl acetate 16.51
    1,2,4-trichlorobenzene 22.52
    4-methylpyridine 32.15
    dibutyl ether 18.36
    2,6-dimethyl-4-heptanol 20.66
    DEF 67.31
    dimethyl isosorbide 105.66
    tetrachloroethylene 40.38
    eugenol 57.24
    triacetin 47.43
    span 80 87.34
    1,4-butanediol 151.73
    1,1-dichloroethane 20.49
    2-methyl-1-pentanol 48.79
    methyl formate 104.4
    2-methyl-1-butanol 80.24
    n-decane 4.0
    butyronitrile 39.29
    3,7-dimethyl-1-octanol 34.48
    1-chlorooctane 11.63
    1-chlorotetradecane 5.98
    n-nonane 3.8
    undecane 3.15
    tert-butylcyclohexane 4.25
    cyclooctane 3.24
    cyclopentanol 136.41
    tetrahydropyran 71.35
    tert-amyl methyl ether 30.34
    2,5,8-trioxanonane 137.86
    1-hexene 7.71
    2-isopropoxyethanol 88.83
    2,2,2-trifluoroethanol 129.03
    methyl butyrate 30.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction