2-(2-Hydroxy-1-oxopropoxy)propionic acid

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  • Identifiers

    CAS number
    617-57-2

    Molecular formula
    C6H10O5

    SMILES
    CC(C(=O)OC(C)C(=O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Buttery 60.08%
    Caramellic 58.88%
    Sour 42.67%
    Creamy 42.28%
    Milky 41.74%
    Fatty 35.7%
    Dairy 35.13%
    Fruity 33.77%
    Odorless 32.97%
    Sweet 31.1%

     

    Flavor
    Odorless 49.97%
    Fruity 43.17%
    Very mild 34.1%
    Creamy 32.11%
    Sour 30.25%
    Buttery 29.65%
    Mild 25.36%
    Caramellic 24.74%
    Sweet-like 21.24%
    Musty 21.17%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.1

    pKa est.
    5.58 (weak acid)

    Molecular weight
    162.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    273°C

    Flash point

    • 133.95 ˚C est.

  • Synonyms

    • 617-57-2
    • 2-(2-Hydroxy-1-oxopropoxy)propionic acid
    • Lactic acid lactate
    • 2-(2-hydroxypropanoyloxy)propanoic acid
    • Lactic acid dimer
    • Propanoic acid, 2-hydroxy-, 1-carboxyethyl ester
    • N37QW3EK1L
    • 2-((2-Hydroxypropanoyl)oxy)propanoic acid
    • 2-[(2-Hydroxypropanoyl)oxy]propanoic acid
    • UNII-N37QW3EK1L
    • lactylic acid
    • EINECS 210-520-1
    • DL-lactic acid lactate
    • starbld0004316
    • 2-LACTYLIC ACID
    • SCHEMBL44463
    • DTXSID30862299
    • LACTIC ACID LACTATE [MI]
    • LACTIC ACID LACTATE, DL-
    • OZZQHCBFUVFZGT-UHFFFAOYSA-N
    • 2-(2-hydroxy-propanoyloxy)-propionic acid
    • 2-(2-Hydroxy-1-Oxopropoxy) Propionic Acid
    • NS00042206
    • Q27284504
    • 65959C69-D35C-4011-BA3E-953F781E2C78
    • 617-57-2

  • Applications

    2-(2-Hydroxy-1-oxopropoxy)propionic acid (CAS 617-57-2) is primarily used as a chemical intermediate and building block in specialty synthesis. In industrial manufacturing, it may serve as a precursor for the synthesis of esters and for incorporation into novel polyesters or other polymer architectures, functioning as a functionalized monomer or compatibilizer in some formulations. It may also act as a processing aid or solvent-related component in coatings, inks, and cleaning formulations, leveraging its ester and hydroxy-keto functionalities. In fragrance and cosmetics, it may be encountered as a fragrance intermediate or fixative component in certain formulations. It is also evaluated as a synthetic intermediate in pharmaceutical and agrochemical development and, when used in polymer systems, can contribute to stabilization or plasticization depending on the formulation. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 217.19
    methanol 412.92
    isopropanol 127.96
    water 188.47
    ethyl acetate 27.78
    n-propanol 123.21
    acetone 135.75
    n-butanol 93.79
    acetonitrile 49.15
    DMF 604.47
    toluene 14.36
    isobutanol 71.74
    1,4-dioxane 184.56
    methyl acetate 39.27
    THF 120.63
    2-butanone 57.37
    n-pentanol 60.4
    sec-butanol 88.74
    n-hexane 6.13
    ethylene glycol 203.31
    NMP 390.48
    cyclohexane 13.05
    DMSO 1167.71
    n-butyl acetate 15.83
    n-octanol 36.24
    chloroform 19.14
    n-propyl acetate 15.33
    acetic acid 116.73
    dichloromethane 57.91
    cyclohexanone 75.64
    propylene glycol 119.6
    isopropyl acetate 15.76
    DMAc 480.46
    2-ethoxyethanol 197.41
    isopentanol 66.06
    n-heptane 7.78
    ethyl formate 60.67
    1,2-dichloroethane 63.74
    n-hexanol 34.48
    2-methoxyethanol 369.41
    isobutyl acetate 6.42
    tetrachloromethane 4.16
    n-pentyl acetate 19.07
    transcutol 172.09
    n-heptanol 32.32
    ethylbenzene 13.88
    MIBK 20.93
    2-propoxyethanol 94.93
    tert-butanol 134.81
    MTBE 52.91
    2-butoxyethanol 74.45
    propionic acid 64.98
    o-xylene 26.46
    formic acid 312.85
    diethyl ether 49.25
    m-xylene 15.08
    p-xylene 17.6
    chlorobenzene 12.9
    dimethyl carbonate 32.72
    n-octane 4.88
    formamide 381.71
    cyclopentanone 87.71
    2-pentanone 39.61
    anisole 33.84
    cyclopentyl methyl ether 40.42
    gamma-butyrolactone 115.85
    1-methoxy-2-propanol 176.36
    pyridine 61.43
    3-pentanone 34.31
    furfural 149.3
    n-dodecane 3.74
    diethylene glycol 147.84
    diisopropyl ether 12.44
    tert-amyl alcohol 102.04
    acetylacetone 50.91
    n-hexadecane 3.96
    acetophenone 37.62
    methyl propionate 40.98
    isopentyl acetate 14.36
    trichloroethylene 47.91
    n-nonanol 32.03
    cyclohexanol 58.23
    benzyl alcohol 51.65
    2-ethylhexanol 20.47
    isooctanol 24.49
    dipropyl ether 23.33
    1,2-dichlorobenzene 16.96
    ethyl lactate 26.26
    propylene carbonate 44.47
    n-methylformamide 259.82
    2-pentanol 46.4
    n-pentane 9.37
    1-propoxy-2-propanol 54.89
    1-methoxy-2-propyl acetate 27.92
    2-(2-methoxypropoxy) propanol 75.26
    mesitylene 12.33
    ε-caprolactone 68.82
    p-cymene 12.54
    epichlorohydrin 120.38
    1,1,1-trichloroethane 11.85
    2-aminoethanol 201.22
    morpholine-4-carbaldehyde 344.84
    sulfolane 271.13
    2,2,4-trimethylpentane 4.88
    2-methyltetrahydrofuran 71.24
    n-hexyl acetate 28.21
    isooctane 2.29
    2-(2-butoxyethoxy)ethanol 95.77
    sec-butyl acetate 8.75
    tert-butyl acetate 19.87
    decalin 5.4
    glycerin 197.44
    diglyme 171.84
    acrylic acid 77.83
    isopropyl myristate 13.01
    n-butyric acid 50.92
    acetyl acetate 17.01
    di(2-ethylhexyl) phthalate 22.52
    ethyl propionate 17.0
    nitromethane 200.03
    1,2-diethoxyethane 45.27
    benzonitrile 28.85
    trioctyl phosphate 18.78
    1-bromopropane 25.62
    gamma-valerolactone 193.79
    n-decanol 25.94
    triethyl phosphate 14.65
    4-methyl-2-pentanol 22.35
    propionitrile 30.47
    vinylene carbonate 50.08
    1,1,2-trichlorotrifluoroethane 114.59
    DMS 22.73
    cumene 12.42
    2-octanol 21.25
    2-hexanone 21.89
    octyl acetate 20.38
    limonene 16.61
    1,2-dimethoxyethane 229.35
    ethyl orthosilicate 14.35
    tributyl phosphate 16.25
    diacetone alcohol 53.23
    N,N-dimethylaniline 44.88
    acrylonitrile 50.12
    aniline 33.49
    1,3-propanediol 194.4
    bromobenzene 10.59
    dibromomethane 32.31
    1,1,2,2-tetrachloroethane 50.06
    2-methyl-cyclohexyl acetate 17.25
    tetrabutyl urea 34.14
    diisobutyl methanol 15.28
    2-phenylethanol 31.19
    styrene 13.98
    dioctyl adipate 24.14
    dimethyl sulfate 87.68
    ethyl butyrate 14.94
    methyl lactate 60.8
    butyl lactate 27.68
    diethyl carbonate 10.88
    propanediol butyl ether 74.24
    triethyl orthoformate 15.55
    p-tert-butyltoluene 12.41
    methyl 4-tert-butylbenzoate 49.25
    morpholine 187.33
    tert-butylamine 62.51
    n-dodecanol 20.6
    dimethoxymethane 198.15
    ethylene carbonate 39.86
    cyrene 86.29
    2-ethoxyethyl acetate 33.06
    2-ethylhexyl acetate 11.15
    1,2,4-trichlorobenzene 20.96
    4-methylpyridine 55.67
    dibutyl ether 20.29
    2,6-dimethyl-4-heptanol 15.28
    DEF 117.41
    dimethyl isosorbide 80.87
    tetrachloroethylene 36.2
    eugenol 53.79
    triacetin 33.94
    span 80 55.83
    1,4-butanediol 106.01
    1,1-dichloroethane 21.8
    2-methyl-1-pentanol 46.37
    methyl formate 183.83
    2-methyl-1-butanol 66.2
    n-decane 5.46
    butyronitrile 32.21
    3,7-dimethyl-1-octanol 26.82
    1-chlorooctane 13.47
    1-chlorotetradecane 6.72
    n-nonane 5.52
    undecane 4.45
    tert-butylcyclohexane 3.73
    cyclooctane 6.28
    cyclopentanol 69.21
    tetrahydropyran 67.48
    tert-amyl methyl ether 49.21
    2,5,8-trioxanonane 132.11
    1-hexene 13.21
    2-isopropoxyethanol 87.86
    2,2,2-trifluoroethanol 62.86
    methyl butyrate 28.15

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction