2-(2-(2-Methoxy-1-methyl-ethoxy)-1-methyl-ethoxy)propan-1-OL

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  • Identifiers

    Molecular formula
    C10H22O4

    SMILES
    CC(CO)OC(C)COC(C)COC

  • Odor profile

    Fragrance
    Fruity 50.27%
    Alcoholic 40.44%
    Ethereal 37.68%
    Odorless 31.53%
    Buttery 29.2%
    Solvent 20.98%
    Fermented 20.84%
    Sweet 20.26%
    Oily 19.28%
    Nutty 17.37%

     

    Flavor
    Fruity 42.91%
    Onion 31.27%
    Alcoholic 28.61%
    Vegetable 27.64%
    Musty 26.09%
    Oily 25.81%
    Creamy 25.6%
    Bitter 25.23%
    Sulfurous 24.59%
    Fatty 23.92%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    0.2

    pKa est.
    6.22 (neutral)

    Molecular weight
    206.28 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    242°C

    Flash point

    • 111.21 ˚C est.

  • Synonyms

    • Dowanol TPM
    • 20V3X25LZO
    • (2-(2-METHOXYMETHYLETHOXY)METHYLETHOXY)PROPANOL
    • 2-(2-(2-methoxy-1-methyl-ethoxy)-1-methyl-ethoxy)propan-1-ol
    • Tripropylene Glycol Monomethyl Ether (mixture of isomer)
    • Arcosolv TPM
    • PPG-3 Methyl ether
    • [2-(2-Methoxymethylethoxy)methylethoxy]propanol
    • O-Methyltripropylene glycol
    • EINECS 247-045-4
    • Tripropylenglykolmonomethylether [Czech]
    • Propanol, 3-(3-(3-methoxypropoxy)propoxy)-
    • Tripropylenglykolmonomethylether
    • SCHEMBL2847449
    • UNII-1827NY57O3
    • 1827NY57O3
    • NCGC00249047-01
    • AS-86501
    • NS00009976
    • EC 247-045-4
    • Q27896602

  • Applications

    Commonly evaluated as a solvent and processing aid in industrial manufacturing, the compound 2-(2-(2-Methoxy-1-methyl-ethoxy)-1-methyl-ethoxy)propan-1-OL can act as a plasticizer for polymers and coatings, enhancing flexibility and film formation. It may function as a nonionic surfactant or co-surfactant in coatings, inks, and cleaning formulations due to its multiple ether groups. In cosmetics and personal care, it can serve as an emollient and solvent, supporting formulation stability and texture. It is also used as an intermediate in the synthesis of specialty chemicals and tailored ethers, enabling further chemical elaboration. Additionally, it can find use in household cleaning formulations as a solvent and solubilizer for active ingredients, and in general formulation contexts where a polar, low-volatile solvent is desirable.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1340.67
    methanol 2383.76
    isopropanol 801.82
    water 113.44
    ethyl acetate 446.48
    n-propanol 947.66
    acetone 560.38
    n-butanol 688.68
    acetonitrile 469.25
    DMF 843.57
    toluene 103.74
    isobutanol 573.26
    1,4-dioxane 859.79
    methyl acetate 510.46
    THF 724.92
    2-butanone 372.25
    n-pentanol 369.1
    sec-butanol 636.09
    n-hexane 39.4
    ethylene glycol 650.27
    NMP 675.97
    cyclohexane 117.79
    DMSO 1025.91
    n-butyl acetate 243.81
    n-octanol 120.34
    chloroform 1052.13
    n-propyl acetate 233.23
    acetic acid 2830.31
    dichloromethane 872.79
    cyclohexanone 606.68
    propylene glycol 551.14
    isopropyl acetate 222.47
    DMAc 800.64
    2-ethoxyethanol 893.62
    isopentanol 399.12
    n-heptane 34.42
    ethyl formate 430.45
    1,2-dichloroethane 511.65
    n-hexanol 295.77
    2-methoxyethanol 1488.49
    isobutyl acetate 146.62
    tetrachloromethane 244.61
    n-pentyl acetate 137.58
    transcutol 982.88
    n-heptanol 121.97
    ethylbenzene 56.83
    MIBK 139.61
    2-propoxyethanol 529.35
    tert-butanol 809.46
    MTBE 448.38
    2-butoxyethanol 273.13
    propionic acid 972.92
    o-xylene 102.55
    formic acid 1958.99
    diethyl ether 402.1
    m-xylene 79.55
    p-xylene 88.62
    chlorobenzene 176.47
    dimethyl carbonate 124.15
    n-octane 12.71
    formamide 1192.06
    cyclopentanone 516.8
    2-pentanone 243.63
    anisole 135.1
    cyclopentyl methyl ether 383.89
    gamma-butyrolactone 657.7
    1-methoxy-2-propanol 688.53
    pyridine 420.03
    3-pentanone 223.91
    furfural 668.44
    n-dodecane 10.02
    diethylene glycol 619.25
    diisopropyl ether 90.87
    tert-amyl alcohol 616.47
    acetylacetone 281.13
    n-hexadecane 11.07
    acetophenone 166.95
    methyl propionate 316.3
    isopentyl acetate 204.35
    trichloroethylene 940.5
    n-nonanol 102.71
    cyclohexanol 627.73
    benzyl alcohol 195.48
    2-ethylhexanol 155.96
    isooctanol 96.59
    dipropyl ether 156.28
    1,2-dichlorobenzene 184.52
    ethyl lactate 171.1
    propylene carbonate 370.69
    n-methylformamide 714.85
    2-pentanol 353.17
    n-pentane 49.78
    1-propoxy-2-propanol 333.56
    1-methoxy-2-propyl acetate 220.03
    2-(2-methoxypropoxy) propanol 220.56
    mesitylene 56.1
    ε-caprolactone 600.66
    p-cymene 60.75
    epichlorohydrin 656.8
    1,1,1-trichloroethane 438.4
    2-aminoethanol 873.06
    morpholine-4-carbaldehyde 757.54
    sulfolane 734.17
    2,2,4-trimethylpentane 42.18
    2-methyltetrahydrofuran 585.19
    n-hexyl acetate 184.88
    isooctane 18.82
    2-(2-butoxyethoxy)ethanol 293.79
    sec-butyl acetate 152.52
    tert-butyl acetate 207.45
    decalin 36.43
    glycerin 830.84
    diglyme 584.16
    acrylic acid 840.64
    isopropyl myristate 69.93
    n-butyric acid 991.21
    acetyl acetate 349.67
    di(2-ethylhexyl) phthalate 87.52
    ethyl propionate 182.57
    nitromethane 1758.63
    1,2-diethoxyethane 254.85
    benzonitrile 195.02
    trioctyl phosphate 65.93
    1-bromopropane 286.97
    gamma-valerolactone 776.26
    n-decanol 70.62
    triethyl phosphate 123.73
    4-methyl-2-pentanol 145.17
    propionitrile 337.56
    vinylene carbonate 391.17
    1,1,2-trichlorotrifluoroethane 1023.49
    DMS 168.44
    cumene 50.29
    2-octanol 75.91
    2-hexanone 169.03
    octyl acetate 92.18
    limonene 109.1
    1,2-dimethoxyethane 810.19
    ethyl orthosilicate 121.92
    tributyl phosphate 89.62
    diacetone alcohol 264.35
    N,N-dimethylaniline 114.0
    acrylonitrile 394.24
    aniline 243.43
    1,3-propanediol 1095.74
    bromobenzene 143.77
    dibromomethane 573.07
    1,1,2,2-tetrachloroethane 785.59
    2-methyl-cyclohexyl acetate 167.43
    tetrabutyl urea 102.48
    diisobutyl methanol 85.28
    2-phenylethanol 161.29
    styrene 72.42
    dioctyl adipate 127.02
    dimethyl sulfate 244.96
    ethyl butyrate 175.5
    methyl lactate 235.69
    butyl lactate 152.2
    diethyl carbonate 136.09
    propanediol butyl ether 253.04
    triethyl orthoformate 162.24
    p-tert-butyltoluene 60.15
    methyl 4-tert-butylbenzoate 172.13
    morpholine 1073.97
    tert-butylamine 457.79
    n-dodecanol 53.16
    dimethoxymethane 393.93
    ethylene carbonate 352.39
    cyrene 240.64
    2-ethoxyethyl acetate 202.36
    2-ethylhexyl acetate 169.24
    1,2,4-trichlorobenzene 237.82
    4-methylpyridine 334.84
    dibutyl ether 120.44
    2,6-dimethyl-4-heptanol 85.28
    DEF 408.19
    dimethyl isosorbide 310.26
    tetrachloroethylene 710.77
    eugenol 170.75
    triacetin 249.1
    span 80 205.45
    1,4-butanediol 443.61
    1,1-dichloroethane 469.02
    2-methyl-1-pentanol 257.0
    methyl formate 537.46
    2-methyl-1-butanol 455.03
    n-decane 18.26
    butyronitrile 305.23
    3,7-dimethyl-1-octanol 115.29
    1-chlorooctane 67.96
    1-chlorotetradecane 26.29
    n-nonane 18.51
    undecane 12.64
    tert-butylcyclohexane 33.62
    cyclooctane 30.75
    cyclopentanol 599.37
    tetrahydropyran 738.35
    tert-amyl methyl ether 332.02
    2,5,8-trioxanonane 370.16
    1-hexene 97.37
    2-isopropoxyethanol 440.08
    2,2,2-trifluoroethanol 1067.67
    methyl butyrate 276.54

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction