2-(2-(2-Hydroxypropoxy)propoxy)-1-propanol

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  • Identifiers

    CAS number
    24800-44-0

    Molecular formula
    C9H20O4

    SMILES
    CC(CO)OCC(C)OCC(C)O

  • Odor profile

    Fragrance
    Odorless 42.56%
    Fruity 39.9%
    Alcoholic 35.99%
    Buttery 31.7%
    Ethereal 25.42%
    Sweet 19.69%
    Milky 19.12%
    Oily 18.71%
    Creamy 17.74%
    Solvent 17.39%

     

    Flavor
    Fruity 44.26%
    Odorless 37.2%
    Onion 32.86%
    Creamy 32.67%
    Alcoholic 30.22%
    Buttery 28.7%
    Fruit 28.18%
    Musty 26.84%
    Oily 25.48%
    Bitter 25.3%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.4

    pKa est.
    7.28 (neutral)

    Molecular weight
    192.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    266°C

    Flash point

    • 131.09 ˚C est.

  • Synonyms

    • 24800-44-0
    • 2-[2-(2-hydroxypropoxy)propoxy]propan-1-ol
    • 2-(2-(2-Hydroxypropoxy)propoxy)propan-1-ol
    • ((Methylethylene)bis(oxy))dipropanol
    • 2-(2-(2-Hydroxypropoxy)propoxy)-1-propanol
    • 45096-22-8
    • 5U049772F7
    • 1-Propanol, 2-(2-(2-hydroxypropoxy)propoxy)-
    • HSDB 2655
    • EINECS 246-466-0
    • BRN 2235421
    • AI3-14657
    • EC 246-466-0
    • SCHEMBL15169
    • UNII-3C8845E7C1
    • DTXSID90871342
    • UNII-5U049772F7
    • AKOS015899581
    • 3C8845E7C1
    • SB83838
    • NCGC00164417-02
    • LS-13724
    • NS00077386
    • 1,4,7-TRIMETHYL-3,6-DIOXAOCTANE-1,8-DIOL
    • Q27262866

  • Applications

    2-(2-(2-Hydroxypropoxy)propoxy)-1-propanol (CAS 24800-44-0) is a triol ether commonly used as a reactive polyol in polyurethane and polyether polyol formulations, where it can act as a crosslinking or chain-extending component in adhesives, coatings, and elastomer systems. It is also employed as a plasticizer and processing aid to improve flexibility and handleability of polymers, and as a humectant or surfactant in cosmetics and personal care products, as well as a functional additive in household cleaning formulations. In industrial manufacturing, it may serve as an intermediate for the synthesis of customized polyether platforms and can function as a solvent or co-solvent in formulation blends, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 284.84
    methanol 656.17
    isopropanol 164.93
    water 71.78
    ethyl acetate 37.92
    n-propanol 194.7
    acetone 68.93
    n-butanol 132.31
    acetonitrile 48.2
    DMF 287.83
    toluene 7.54
    isobutanol 120.66
    1,4-dioxane 136.26
    methyl acetate 50.43
    THF 169.67
    2-butanone 48.56
    n-pentanol 76.94
    sec-butanol 124.57
    n-hexane 3.86
    ethylene glycol 274.38
    NMP 230.33
    cyclohexane 9.37
    DMSO 514.81
    n-butyl acetate 33.82
    n-octanol 43.53
    chloroform 91.1
    n-propyl acetate 33.05
    acetic acid 532.72
    dichloromethane 85.21
    cyclohexanone 116.28
    propylene glycol 275.58
    isopropyl acetate 25.2
    DMAc 257.51
    2-ethoxyethanol 227.06
    isopentanol 81.58
    n-heptane 5.72
    ethyl formate 65.93
    1,2-dichloroethane 49.84
    n-hexanol 67.2
    2-methoxyethanol 414.13
    isobutyl acetate 25.55
    tetrachloromethane 17.05
    n-pentyl acetate 27.67
    transcutol 328.32
    n-heptanol 40.31
    ethylbenzene 8.27
    MIBK 26.52
    2-propoxyethanol 146.51
    tert-butanol 181.72
    MTBE 52.82
    2-butoxyethanol 93.5
    propionic acid 202.82
    o-xylene 13.86
    formic acid 470.91
    diethyl ether 29.9
    m-xylene 10.17
    p-xylene 13.15
    chlorobenzene 17.82
    dimethyl carbonate 22.13
    n-octane 3.0
    formamide 267.86
    cyclopentanone 129.75
    2-pentanone 31.74
    anisole 27.12
    cyclopentyl methyl ether 57.78
    gamma-butyrolactone 170.39
    1-methoxy-2-propanol 202.67
    pyridine 51.46
    3-pentanone 28.21
    furfural 177.42
    n-dodecane 2.96
    diethylene glycol 222.88
    diisopropyl ether 10.03
    tert-amyl alcohol 135.17
    acetylacetone 49.03
    n-hexadecane 3.16
    acetophenone 41.59
    methyl propionate 41.41
    isopentyl acetate 35.51
    trichloroethylene 98.17
    n-nonanol 37.94
    cyclohexanol 116.7
    benzyl alcohol 53.04
    2-ethylhexanol 37.1
    isooctanol 32.97
    dipropyl ether 26.18
    1,2-dichlorobenzene 25.83
    ethyl lactate 54.71
    propylene carbonate 98.16
    n-methylformamide 174.19
    2-pentanol 58.41
    n-pentane 4.11
    1-propoxy-2-propanol 98.27
    1-methoxy-2-propyl acetate 50.54
    2-(2-methoxypropoxy) propanol 102.53
    mesitylene 9.76
    ε-caprolactone 117.91
    p-cymene 13.57
    epichlorohydrin 130.39
    1,1,1-trichloroethane 33.62
    2-aminoethanol 309.63
    morpholine-4-carbaldehyde 240.9
    sulfolane 282.2
    2,2,4-trimethylpentane 5.29
    2-methyltetrahydrofuran 96.66
    n-hexyl acetate 47.34
    isooctane 3.04
    2-(2-butoxyethoxy)ethanol 122.21
    sec-butyl acetate 21.61
    tert-butyl acetate 35.07
    decalin 5.73
    glycerin 394.76
    diglyme 203.09
    acrylic acid 195.54
    isopropyl myristate 20.69
    n-butyric acid 178.11
    acetyl acetate 39.97
    di(2-ethylhexyl) phthalate 34.96
    ethyl propionate 28.42
    nitromethane 280.72
    1,2-diethoxyethane 48.95
    benzonitrile 40.44
    trioctyl phosphate 27.33
    1-bromopropane 23.19
    gamma-valerolactone 200.83
    n-decanol 27.65
    triethyl phosphate 30.98
    4-methyl-2-pentanol 32.28
    propionitrile 44.93
    vinylene carbonate 91.69
    1,1,2-trichlorotrifluoroethane 248.5
    DMS 37.44
    cumene 10.37
    2-octanol 24.85
    2-hexanone 30.85
    octyl acetate 28.15
    limonene 21.87
    1,2-dimethoxyethane 198.04
    ethyl orthosilicate 29.26
    tributyl phosphate 31.31
    diacetone alcohol 77.19
    N,N-dimethylaniline 30.62
    acrylonitrile 66.84
    aniline 34.3
    1,3-propanediol 319.73
    bromobenzene 13.53
    dibromomethane 51.89
    1,1,2,2-tetrachloroethane 100.29
    2-methyl-cyclohexyl acetate 43.43
    tetrabutyl urea 40.74
    diisobutyl methanol 23.53
    2-phenylethanol 41.49
    styrene 9.07
    dioctyl adipate 43.38
    dimethyl sulfate 64.2
    ethyl butyrate 32.15
    methyl lactate 79.81
    butyl lactate 52.62
    diethyl carbonate 25.66
    propanediol butyl ether 123.8
    triethyl orthoformate 33.57
    p-tert-butyltoluene 14.01
    methyl 4-tert-butylbenzoate 58.67
    morpholine 197.09
    tert-butylamine 77.59
    n-dodecanol 21.44
    dimethoxymethane 81.51
    ethylene carbonate 74.26
    cyrene 108.89
    2-ethoxyethyl acetate 40.5
    2-ethylhexyl acetate 26.95
    1,2,4-trichlorobenzene 37.0
    4-methylpyridine 44.74
    dibutyl ether 26.12
    2,6-dimethyl-4-heptanol 23.53
    DEF 82.46
    dimethyl isosorbide 127.78
    tetrachloroethylene 79.0
    eugenol 66.54
    triacetin 74.54
    span 80 95.1
    1,4-butanediol 142.86
    1,1-dichloroethane 33.47
    2-methyl-1-pentanol 59.44
    methyl formate 116.84
    2-methyl-1-butanol 91.74
    n-decane 4.51
    butyronitrile 44.62
    3,7-dimethyl-1-octanol 40.56
    1-chlorooctane 15.15
    1-chlorotetradecane 7.07
    n-nonane 4.32
    undecane 3.47
    tert-butylcyclohexane 5.59
    cyclooctane 4.12
    cyclopentanol 137.43
    tetrahydropyran 88.63
    tert-amyl methyl ether 44.58
    2,5,8-trioxanonane 161.26
    1-hexene 10.07
    2-isopropoxyethanol 118.01
    2,2,2-trifluoroethanol 205.68
    methyl butyrate 47.45

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction