2-(2-(2-Butoxyethoxy)ethoxy)acetic acid

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  • Identifiers

    CAS number
    75427-76-8

    Molecular formula
    C10H20O5

    SMILES
    CCCCOCCOCCOCC(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Fruity 37.8%
    Alcoholic 37.79%
    Ethereal 35.69%
    Odorless 33.91%
    Buttery 27.89%
    Oily 26.92%
    Sweet 23.77%
    Caramellic 22.79%
    Solvent 22.18%
    Fermented 21.44%

     

    Flavor
    Sweet 35.76%
    Fatty 33.58%
    Odorless 33.24%
    Musty 28.22%
    Vegetable 28.03%
    Oily 26.73%
    Creamy 24.36%
    Cheese 23.86%
    Very slight 23.24%
    Sweet-like 22.77%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    5.01 (weak acid)

    Molecular weight
    220.26 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    317°C

    Flash point

    • 159.12 ˚C est.

  • Synonyms

    • 75427-76-8
    • SCHEMBL2952562
    • UUDGIIFVQITGGK-UHFFFAOYSA-N
    • DTXSID401021304
    • 2-(2-(2-Butoxyethoxy)ethoxy)acetic acid
    • 2-[2-(2-Butoxyethoxy)ethoxy]-acetic acid
    • 75427-76-8

  • Applications

    2-(2-(2-Butoxyethoxy)ethoxy)acetic acid (CAS 75427-76-8) is an alkyl ether carboxylate with a short polyether chain that makes it useful as a surfactant and co-solvent. In practice, it is commonly used to improve wetting, emulsification and pigment dispersion in coatings, inks and cleaning formulations. It also serves as an intermediate in the synthesis of glycol ether carboxylates and specialty additives for plastics and polymers. In cosmetics and personal care, it may function as a surfactant or solubilizer. Owing to its carboxyl group and ether backbone, it can be incorporated into formulations as a functional linker or salt-forming component, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 129.06
    methanol 394.48
    isopropanol 47.36
    water 12.82
    ethyl acetate 27.13
    n-propanol 72.64
    acetone 66.68
    n-butanol 47.33
    acetonitrile 32.82
    DMF 339.61
    toluene 7.67
    isobutanol 43.01
    1,4-dioxane 58.6
    methyl acetate 30.7
    THF 91.72
    2-butanone 31.55
    n-pentanol 33.24
    sec-butanol 36.49
    n-hexane 2.03
    ethylene glycol 122.91
    NMP 307.05
    cyclohexane 6.4
    DMSO 1133.4
    n-butyl acetate 25.75
    n-octanol 16.37
    chloroform 74.86
    n-propyl acetate 27.17
    acetic acid 328.27
    dichloromethane 100.74
    cyclohexanone 92.75
    propylene glycol 101.33
    isopropyl acetate 17.05
    DMAc 250.92
    2-ethoxyethanol 126.57
    isopentanol 34.03
    n-heptane 2.74
    ethyl formate 42.58
    1,2-dichloroethane 79.61
    n-hexanol 25.99
    2-methoxyethanol 245.34
    isobutyl acetate 17.31
    tetrachloromethane 13.05
    n-pentyl acetate 17.8
    transcutol 309.71
    n-heptanol 14.24
    ethylbenzene 6.95
    MIBK 18.85
    2-propoxyethanol 76.84
    tert-butanol 57.7
    MTBE 15.42
    2-butoxyethanol 44.79
    propionic acid 120.4
    o-xylene 14.24
    formic acid 330.81
    diethyl ether 12.43
    m-xylene 11.11
    p-xylene 10.51
    chlorobenzene 18.12
    dimethyl carbonate 21.18
    n-octane 1.32
    formamide 328.52
    cyclopentanone 108.09
    2-pentanone 24.57
    anisole 21.3
    cyclopentyl methyl ether 38.14
    gamma-butyrolactone 152.4
    1-methoxy-2-propanol 120.51
    pyridine 49.73
    3-pentanone 23.05
    furfural 171.52
    n-dodecane 1.22
    diethylene glycol 124.64
    diisopropyl ether 4.99
    tert-amyl alcohol 45.06
    acetylacetone 52.47
    n-hexadecane 1.37
    acetophenone 39.49
    methyl propionate 33.88
    isopentyl acetate 24.44
    trichloroethylene 123.89
    n-nonanol 15.26
    cyclohexanol 59.15
    benzyl alcohol 39.67
    2-ethylhexanol 16.54
    isooctanol 12.83
    dipropyl ether 14.27
    1,2-dichlorobenzene 28.45
    ethyl lactate 41.56
    propylene carbonate 74.88
    n-methylformamide 172.02
    2-pentanol 19.03
    n-pentane 2.12
    1-propoxy-2-propanol 50.09
    1-methoxy-2-propyl acetate 38.18
    2-(2-methoxypropoxy) propanol 71.6
    mesitylene 10.11
    ε-caprolactone 82.82
    p-cymene 9.92
    epichlorohydrin 116.74
    1,1,1-trichloroethane 34.58
    2-aminoethanol 164.65
    morpholine-4-carbaldehyde 205.06
    sulfolane 367.67
    2,2,4-trimethylpentane 2.2
    2-methyltetrahydrofuran 45.51
    n-hexyl acetate 27.02
    isooctane 1.26
    2-(2-butoxyethoxy)ethanol 85.47
    sec-butyl acetate 14.97
    tert-butyl acetate 24.44
    decalin 3.53
    glycerin 198.68
    diglyme 152.7
    acrylic acid 136.52
    isopropyl myristate 11.95
    n-butyric acid 99.32
    acetyl acetate 32.75
    di(2-ethylhexyl) phthalate 23.81
    ethyl propionate 22.62
    nitromethane 269.76
    1,2-diethoxyethane 35.95
    benzonitrile 31.24
    trioctyl phosphate 15.55
    1-bromopropane 19.94
    gamma-valerolactone 165.92
    n-decanol 11.38
    triethyl phosphate 26.5
    4-methyl-2-pentanol 12.46
    propionitrile 27.07
    vinylene carbonate 77.0
    1,1,2-trichlorotrifluoroethane 234.02
    DMS 36.87
    cumene 8.11
    2-octanol 8.72
    2-hexanone 22.26
    octyl acetate 16.61
    limonene 14.82
    1,2-dimethoxyethane 119.29
    ethyl orthosilicate 22.56
    tributyl phosphate 21.31
    diacetone alcohol 54.41
    N,N-dimethylaniline 25.72
    acrylonitrile 51.61
    aniline 27.82
    1,3-propanediol 149.55
    bromobenzene 16.15
    dibromomethane 55.64
    1,1,2,2-tetrachloroethane 124.29
    2-methyl-cyclohexyl acetate 31.08
    tetrabutyl urea 33.34
    diisobutyl methanol 11.76
    2-phenylethanol 29.67
    styrene 7.98
    dioctyl adipate 31.55
    dimethyl sulfate 79.69
    ethyl butyrate 25.35
    methyl lactate 59.64
    butyl lactate 34.95
    diethyl carbonate 22.08
    propanediol butyl ether 67.15
    triethyl orthoformate 24.91
    p-tert-butyltoluene 9.62
    methyl 4-tert-butylbenzoate 46.89
    morpholine 103.24
    tert-butylamine 25.94
    n-dodecanol 8.97
    dimethoxymethane 76.68
    ethylene carbonate 56.6
    cyrene 92.36
    2-ethoxyethyl acetate 31.08
    2-ethylhexyl acetate 18.76
    1,2,4-trichlorobenzene 39.1
    4-methylpyridine 36.26
    dibutyl ether 13.87
    2,6-dimethyl-4-heptanol 11.76
    DEF 71.66
    dimethyl isosorbide 111.64
    tetrachloroethylene 86.35
    eugenol 51.2
    triacetin 61.88
    span 80 61.11
    1,4-butanediol 68.87
    1,1-dichloroethane 31.63
    2-methyl-1-pentanol 26.81
    methyl formate 96.68
    2-methyl-1-butanol 36.32
    n-decane 1.96
    butyronitrile 23.69
    3,7-dimethyl-1-octanol 17.96
    1-chlorooctane 8.01
    1-chlorotetradecane 3.71
    n-nonane 1.82
    undecane 1.48
    tert-butylcyclohexane 2.55
    cyclooctane 2.64
    cyclopentanol 64.42
    tetrahydropyran 38.25
    tert-amyl methyl ether 17.06
    2,5,8-trioxanonane 128.14
    1-hexene 5.68
    2-isopropoxyethanol 58.05
    2,2,2-trifluoroethanol 133.62
    methyl butyrate 38.41

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction