(1R*,4R*)-1-hydroxy-1,4,7,7,9,9-hexamethylspiro[4.5]decan-2-one

Overview IFRA Request a quote

  • Identifiers

    Molecular formula
    C16H28O2

    SMILES
    C[C@@H]1CC(=O)[C@](C12CC(CC(C2)(C)C)(C)C)(C)O

  • Odor profile

    Fragrance
    Woody 83.6%
    Amber 51.62%
    Dry 49.07%
    Cedar 45.07%
    Camphoreous 43.89%
    Musk 43.7%
    Tobacco 41.85%
    Earthy 39.77%
    Spicy 32.66%
    Powdery 30.9%

     

    Flavor
    Woody 67.66%
    Camphor 53.44%
    Herbal 52.58%
    Sweet 48.42%
    Pine 37.41%
    Tobacco 36.6%
    Earthy 34.33%
    Dry 33.71%
    Minty 33.55%
    Spicy 33.18%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.6

    pKa est.
    8.16 (weak base)

    Molecular weight
    252.39 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    344°C

    Flash point

    • 132.62 ˚C est.

  • Synonyms

    • SCHEMBL4396406
    • DLFATRPSUKNSKP-ABAIWWIYSA-N
    • (1R*,4R*)-1-hydroxy-1,4,7,7,9,9-hexamethylspiro[4.5]decan-2-one

  • Applications

    For the compound (1R*,4R*)-1-hydroxy-1,4,7,7,9,9-hexamethylspiro[4.5]decan-2-one, practical applications span fragrance and consumer-care domains: it is used as an odorant and fixative in perfumery; it may serve as a fragrance ingredient in cosmetics and personal care formulations; it can be employed in household deodorizing products and air fresheners; it is commonly evaluated as an intermediate in industrial fragrance synthesis; and it may be incorporated into coatings and inks as a fragrance additive. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 251.96
    methanol 290.82
    isopropanol 343.12
    water 2.14
    ethyl acetate 595.27
    n-propanol 309.07
    acetone 762.9
    n-butanol 309.38
    acetonitrile 385.75
    DMF 1166.44
    toluene 581.55
    isobutanol 292.91
    1,4-dioxane 886.06
    methyl acetate 563.0
    THF 2278.03
    2-butanone 664.12
    n-pentanol 186.81
    sec-butanol 294.32
    n-hexane 44.11
    ethylene glycol 104.53
    NMP 988.75
    cyclohexane 88.37
    DMSO 609.67
    n-butyl acetate 411.48
    n-octanol 207.05
    chloroform 1315.05
    n-propyl acetate 331.52
    acetic acid 262.2
    dichloromethane 808.76
    cyclohexanone 1030.26
    propylene glycol 173.06
    isopropyl acetate 539.37
    DMAc 792.99
    2-ethoxyethanol 275.75
    isopentanol 275.01
    n-heptane 41.85
    ethyl formate 349.71
    1,2-dichloroethane 584.1
    n-hexanol 324.01
    2-methoxyethanol 532.91
    isobutyl acetate 286.57
    tetrachloromethane 268.34
    n-pentyl acetate 339.3
    transcutol 411.16
    n-heptanol 207.24
    ethylbenzene 268.71
    MIBK 475.12
    2-propoxyethanol 558.61
    tert-butanol 421.72
    MTBE 467.41
    2-butoxyethanol 349.2
    propionic acid 305.89
    o-xylene 335.93
    formic acid 114.82
    diethyl ether 410.39
    m-xylene 458.93
    p-xylene 330.64
    chlorobenzene 559.23
    dimethyl carbonate 384.94
    n-octane 27.37
    formamide 175.23
    cyclopentanone 1586.89
    2-pentanone 639.12
    anisole 437.79
    cyclopentyl methyl ether 868.97
    gamma-butyrolactone 1503.34
    1-methoxy-2-propanol 584.33
    pyridine 706.98
    3-pentanone 486.77
    furfural 983.46
    n-dodecane 22.08
    diethylene glycol 343.62
    diisopropyl ether 203.83
    tert-amyl alcohol 307.71
    acetylacetone 821.18
    n-hexadecane 26.38
    acetophenone 437.82
    methyl propionate 554.88
    isopentyl acetate 434.53
    trichloroethylene 1223.66
    n-nonanol 182.36
    cyclohexanol 420.22
    benzyl alcohol 306.66
    2-ethylhexanol 190.78
    isooctanol 174.04
    dipropyl ether 242.17
    1,2-dichlorobenzene 531.14
    ethyl lactate 216.14
    propylene carbonate 841.96
    n-methylformamide 465.32
    2-pentanol 254.36
    n-pentane 55.26
    1-propoxy-2-propanol 396.52
    1-methoxy-2-propyl acetate 541.03
    2-(2-methoxypropoxy) propanol 263.64
    mesitylene 280.47
    ε-caprolactone 834.12
    p-cymene 182.05
    epichlorohydrin 1285.59
    1,1,1-trichloroethane 859.69
    2-aminoethanol 175.3
    morpholine-4-carbaldehyde 931.09
    sulfolane 1382.02
    2,2,4-trimethylpentane 39.43
    2-methyltetrahydrofuran 1059.49
    n-hexyl acetate 471.39
    isooctane 38.17
    2-(2-butoxyethoxy)ethanol 310.51
    sec-butyl acetate 280.61
    tert-butyl acetate 579.17
    decalin 61.48
    glycerin 234.12
    diglyme 614.65
    acrylic acid 286.04
    isopropyl myristate 187.18
    n-butyric acid 429.96
    acetyl acetate 478.77
    di(2-ethylhexyl) phthalate 174.19
    ethyl propionate 355.02
    nitromethane 705.13
    1,2-diethoxyethane 258.28
    benzonitrile 469.58
    trioctyl phosphate 146.89
    1-bromopropane 380.14
    gamma-valerolactone 1514.93
    n-decanol 135.6
    triethyl phosphate 166.62
    4-methyl-2-pentanol 191.05
    propionitrile 424.32
    vinylene carbonate 709.38
    1,1,2-trichlorotrifluoroethane 691.08
    DMS 443.93
    cumene 189.58
    2-octanol 176.3
    2-hexanone 323.6
    octyl acetate 234.4
    limonene 216.4
    1,2-dimethoxyethane 552.53
    ethyl orthosilicate 151.75
    tributyl phosphate 155.75
    diacetone alcohol 509.16
    N,N-dimethylaniline 306.61
    acrylonitrile 485.01
    aniline 451.04
    1,3-propanediol 264.97
    bromobenzene 616.54
    dibromomethane 561.04
    1,1,2,2-tetrachloroethane 1011.31
    2-methyl-cyclohexyl acetate 290.68
    tetrabutyl urea 202.92
    diisobutyl methanol 137.24
    2-phenylethanol 375.75
    styrene 279.5
    dioctyl adipate 229.54
    dimethyl sulfate 594.4
    ethyl butyrate 303.8
    methyl lactate 336.46
    butyl lactate 274.27
    diethyl carbonate 210.6
    propanediol butyl ether 302.42
    triethyl orthoformate 211.87
    p-tert-butyltoluene 198.12
    methyl 4-tert-butylbenzoate 432.23
    morpholine 891.95
    tert-butylamine 257.02
    n-dodecanol 101.5
    dimethoxymethane 793.26
    ethylene carbonate 600.13
    cyrene 362.96
    2-ethoxyethyl acetate 404.3
    2-ethylhexyl acetate 337.23
    1,2,4-trichlorobenzene 555.91
    4-methylpyridine 825.21
    dibutyl ether 187.04
    2,6-dimethyl-4-heptanol 137.24
    DEF 542.63
    dimethyl isosorbide 581.47
    tetrachloroethylene 622.36
    eugenol 350.44
    triacetin 385.37
    span 80 266.7
    1,4-butanediol 117.4
    1,1-dichloroethane 729.41
    2-methyl-1-pentanol 163.1
    methyl formate 476.68
    2-methyl-1-butanol 255.5
    n-decane 40.58
    butyronitrile 419.23
    3,7-dimethyl-1-octanol 184.83
    1-chlorooctane 167.91
    1-chlorotetradecane 65.35
    n-nonane 38.02
    undecane 29.12
    tert-butylcyclohexane 57.82
    cyclooctane 44.22
    cyclopentanol 533.04
    tetrahydropyran 898.98
    tert-amyl methyl ether 340.27
    2,5,8-trioxanonane 387.82
    1-hexene 144.52
    2-isopropoxyethanol 238.79
    2,2,2-trifluoroethanol 208.33
    methyl butyrate 416.38

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction