1H-Indol-2-ol

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    16990-73-1

    Molecular formula
    C8H7NO

    SMILES
    C1=CC=C2C(=C1)C=C(N2)O

  • Odor profile

    Phenolic 47.97%
    Animal 40.57%
    Burnt 38.06%
    Fruity 33.78%
    Meaty 33.52%
    Musty 27.05%
    Odorless 26.73%
    Cheesy 26.26%
    Smoky 24.1%
    Medicinal 23.7%

    Scent© AI

  • Properties

    XLogP3-AA
    2.4

    pKa est.
    9.37 (weak base)

    Molecular weight
    133.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    361°C

    Flash point est.
    170.79 ˚C

  • Synonyms

    • 1H-Indol-2-ol
    • 2-HYDROXYINDOLE
    • 16990-73-1
    • EINECS 241-069-9
    • DTXSID10937712
    • hydroxy-indole
    • SCHEMBL186718
    • SCHEMBL10788658
    • CHEBI:195171
    • DTXCID001156628
    • MFCD00151677
    • AKOS006272440
    • FH156178
    • DB-064758
    • CS-0213354
    • NS00086744
    • F76024

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 24.27
    methanol 26.33
    isopropanol 17.21
    water 1.58
    ethyl acetate 9.99
    n-propanol 18.83
    acetone 27.52
    n-butanol 14.2
    acetonitrile 4.64
    DMF 84.23
    toluene 0.12
    isobutanol 14.36
    1,4-dioxane 20.71
    methyl acetate 15.59
    THF 101.36
    2-butanone 22.41
    n-pentanol 20.47
    sec-butanol 15.61
    n-hexane 0.22
    ethylene glycol 34.71
    NMP 61.7
    cyclohexane 0.02
    DMSO 106.21
    n-butyl acetate 13.1
    n-octanol 15.62
    chloroform 1.47
    n-propyl acetate 14.82
    acetic acid 24.35
    dichloromethane 1.1
    cyclohexanone 13.33
    propylene glycol 33.7
    isopropyl acetate 7.93
    DMAc 87.7
    2-ethoxyethanol 81.37
    isopentanol 15.24
    n-heptane 0.39
    ethyl formate 8.86
    1,2-dichloroethane 1.23
    n-hexanol 25.33
    2-methoxyethanol 99.76
    isobutyl acetate 11.49
    tetrachloromethane 0.85
    n-pentyl acetate 13.28
    transcutol 67.39
    n-heptanol 18.85
    ethylbenzene 0.47
    MIBK 14.72
    2-propoxyethanol 101.65
    tert-butanol 23.7
    MTBE 8.57
    2-butoxyethanol 63.3
    propionic acid 20.82
    o-xylene 0.32
    formic acid 25.12
    diethyl ether 3.74
    m-xylene 0.45
    p-xylene 0.9
    chlorobenzene 0.61
    dimethyl carbonate 13.0
    n-octane 0.27
    formamide 34.94
    cyclopentanone 49.07
    2-pentanone 16.71
    anisole 7.18
    cyclopentyl methyl ether 12.15
    gamma-butyrolactone 57.3
    1-methoxy-2-propanol 77.2
    pyridine 3.43
    3-pentanone 7.92
    furfural 30.01
    n-dodecane 0.4
    diethylene glycol 106.63
    diisopropyl ether 2.13
    tert-amyl alcohol 21.43
    acetylacetone 22.93
    n-hexadecane 0.42
    acetophenone 9.6
    methyl propionate 15.91
    isopentyl acetate 13.29
    trichloroethylene 3.04
    n-nonanol 14.82
    cyclohexanol 4.66
    benzyl alcohol 8.82
    2-ethylhexanol 11.94
    isooctanol 16.26
    dipropyl ether 9.83
    1,2-dichlorobenzene 1.35
    ethyl lactate 21.67
    propylene carbonate 17.98
    n-methylformamide 34.9
    2-pentanol 9.48
    n-pentane 0.08
    1-propoxy-2-propanol 51.21
    1-methoxy-2-propyl acetate 24.08
    2-(2-methoxypropoxy) propanol 46.84
    mesitylene 0.53
    ε-caprolactone 15.94
    p-cymene 1.76
    epichlorohydrin 40.13
    1,1,1-trichloroethane 1.77
    2-aminoethanol 48.63
    morpholine-4-carbaldehyde 61.53
    sulfolane 78.52
    2,2,4-trimethylpentane 0.22
    2-methyltetrahydrofuran 26.88
    n-hexyl acetate 19.01
    isooctane 0.28
    2-(2-butoxyethoxy)ethanol 61.59
    sec-butyl acetate 8.99
    tert-butyl acetate 11.64
    decalin 0.17
    glycerin 73.03
    diglyme 84.26
    acrylic acid 18.37
    isopropyl myristate 9.34
    n-butyric acid 16.88
    acetyl acetate 5.38
    di(2-ethylhexyl) phthalate 12.18
    ethyl propionate 13.42
    nitromethane 42.79
    1,2-diethoxyethane 15.84
    benzonitrile 4.28
    trioctyl phosphate 11.54
    1-bromopropane 0.62
    gamma-valerolactone 58.74
    n-decanol 11.35
    triethyl phosphate 8.6
    4-methyl-2-pentanol 10.2
    propionitrile 5.55
    vinylene carbonate 11.15
    1,1,2-trichlorotrifluoroethane 37.81
    DMS 13.38
    cumene 1.15
    2-octanol 11.97
    2-hexanone 22.19
    octyl acetate 13.29
    limonene 2.14
    1,2-dimethoxyethane 81.52
    ethyl orthosilicate 8.03
    tributyl phosphate 11.03
    diacetone alcohol 35.73
    N,N-dimethylaniline 7.07
    acrylonitrile 8.02
    aniline 1.31
    1,3-propanediol 45.92
    bromobenzene 0.36
    dibromomethane 0.53
    1,1,2,2-tetrachloroethane 3.55
    2-methyl-cyclohexyl acetate 12.06
    tetrabutyl urea 17.11
    diisobutyl methanol 7.83
    2-phenylethanol 13.15
    styrene 0.38
    dioctyl adipate 13.63
    dimethyl sulfate 30.86
    ethyl butyrate 11.15
    methyl lactate 28.33
    butyl lactate 20.77
    diethyl carbonate 7.54
    propanediol butyl ether 44.13
    triethyl orthoformate 10.16
    p-tert-butyltoluene 1.76
    methyl 4-tert-butylbenzoate 22.02
    morpholine 27.19
    tert-butylamine 7.25
    n-dodecanol 8.46
    dimethoxymethane 44.7
    ethylene carbonate 9.18
    cyrene 41.87
    2-ethoxyethyl acetate 20.55
    2-ethylhexyl acetate 9.46
    1,2,4-trichlorobenzene 2.11
    4-methylpyridine 3.14
    dibutyl ether 7.73
    2,6-dimethyl-4-heptanol 7.83
    DEF 18.35
    dimethyl isosorbide 54.38
    tetrachloroethylene 2.75
    eugenol 34.73
    triacetin 19.17
    span 80 31.23
    1,4-butanediol 33.41
    1,1-dichloroethane 1.07
    2-methyl-1-pentanol 19.02
    methyl formate 22.28
    2-methyl-1-butanol 14.08
    n-decane 0.53
    butyronitrile 5.53
    3,7-dimethyl-1-octanol 12.7
    1-chlorooctane 3.07
    1-chlorotetradecane 1.51
    n-nonane 0.43
    undecane 0.45
    tert-butylcyclohexane 0.38
    cyclooctane 0.03
    cyclopentanol 15.99
    tetrahydropyran 6.42
    tert-amyl methyl ether 8.34
    2,5,8-trioxanonane 67.16
    1-hexene 1.2
    2-isopropoxyethanol 53.46
    2,2,2-trifluoroethanol 15.35
    methyl butyrate 16.69

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Jasmine sambac (France) concrete Jasminum sambac (L.) Aiton, fam. Oleaceae 0.5%