1,7-Dioxacycloheptadecan-8-one

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  • Identifiers

    CAS number
    3391-83-1

    Molecular formula
    C15H28O3

    SMILES
    C1CCCCC(=O)OCCCCCOCCCC1

  • Odor profile

    Fragrance
    Sweet 85.61%
    Musk 76.86%
    Fruity 68.9%
    Animal 58.99%
    Floral 49.41%
    Oily 47.31%
    Woody 47.18%
    Waxy 45.88%
    Amber 43.51%
    Powdery 42.41%

     

    Flavor
    Fruity 51.34%
    Animal 35.21%
    Minty 26.54%
    Natural 26.25%
    Musk 23.63%
    Powdery 22.97%
    Shrimp 22.19%
    Alkaline 21.23%
    Caramel 20.72%
    Beet 20.65%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    4.0

    pKa est.
    11.56 (strong base)

    Molecular weight
    256.38 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    336°C

    Flash point

    • 160.72 ˚C est.

  • Synonyms

    • 1,7-Dioxacycloheptadecan-8-one
    • 3391-83-1
    • 11-Oxahexadecanolide
    • 11-Oxahexadecan-16-olide
    • Musk R 1
    • Musk R-1
    • EINECS 222-225-5
    • 1,7-DIOXACYCLOHEPTADECAN-17-ONE
    • 16-Hydroxy-11-oxahexadecanoic acid, omega-lactone
    • Decanoic acid, 10-((5-hydroxypentyl)oxy)-, o-lactone
    • DTXSID2052023
    • 11-Oxa-16-hexadecanolid
    • Musk R 1 98%
    • Oprea1_015798
    • Oprea1_226323
    • SCHEMBL111476
    • DTXCID0030588
    • 11-Oxa-16-hexadecanolide 98%
    • CHEBI:230424
    • MKEIDVFLAWJKMY-UHFFFAOYSA-N
    • AKOS000622958
    • AC-9865
    • AC-18262
    • DS-021012
    • NS00013013
    • AG-664/31380009
    • Decanoic acid, 10-[(5-hydroxypentyl)oxy]-, omicron-lactone
    • Musk R1

  • Applications

    1,7-Dioxacycloheptadecan-8-one is typically considered an intermediate in organic synthesis and a building block for macrocyclic carbonate and polyester derivatives. In polymer and plastics applications, it can serve as a precursor for polyester-type polymers or cyclic carbonate building blocks used in specialty polymer chemistries. In coatings and inks, it may function as a solvent or processing aid for high-performance formulations, enabling dissolution and viscosity control. In electronics, it is evaluated as a specialty solvent or electrolyte component for niche formulations. Additionally, with the potential to act as a reactive diluent or crosslinking agent, it may be used in adhesives and related coating formulations, depending on formulation constraints and regulatory considerations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 885.95
    methanol 1007.6
    isopropanol 786.24
    water 0.16
    ethyl acetate 1322.76
    n-propanol 744.63
    acetone 1467.03
    n-butanol 679.13
    acetonitrile 1040.74
    DMF 1042.48
    toluene 654.13
    isobutanol 566.9
    1,4-dioxane 1322.6
    methyl acetate 753.96
    THF 1944.51
    2-butanone 958.95
    n-pentanol 464.6
    sec-butanol 603.72
    n-hexane 161.94
    ethylene glycol 89.38
    NMP 1062.88
    cyclohexane 404.62
    DMSO 2025.01
    n-butyl acetate 908.57
    n-octanol 253.89
    chloroform 3935.87
    n-propyl acetate 965.53
    acetic acid 1202.97
    dichloromethane 3533.28
    cyclohexanone 1845.41
    propylene glycol 167.61
    isopropyl acetate 860.37
    DMAc 899.99
    2-ethoxyethanol 662.66
    isopentanol 636.32
    n-heptane 111.51
    ethyl formate 665.73
    1,2-dichloroethane 2017.39
    n-hexanol 416.43
    2-methoxyethanol 951.1
    isobutyl acetate 566.52
    tetrachloromethane 497.22
    n-pentyl acetate 748.74
    transcutol 2752.15
    n-heptanol 228.61
    ethylbenzene 326.07
    MIBK 651.83
    2-propoxyethanol 627.9
    tert-butanol 809.69
    MTBE 675.54
    2-butoxyethanol 517.88
    propionic acid 751.06
    o-xylene 372.59
    formic acid 266.89
    diethyl ether 1042.06
    m-xylene 386.17
    p-xylene 438.37
    chlorobenzene 1021.35
    dimethyl carbonate 248.99
    n-octane 43.05
    formamide 439.27
    cyclopentanone 1773.64
    2-pentanone 1037.28
    anisole 544.53
    cyclopentyl methyl ether 1018.59
    gamma-butyrolactone 1919.74
    1-methoxy-2-propanol 770.24
    pyridine 1779.6
    3-pentanone 707.31
    furfural 1588.49
    n-dodecane 29.14
    diethylene glycol 392.82
    diisopropyl ether 303.65
    tert-amyl alcohol 597.31
    acetylacetone 1068.62
    n-hexadecane 34.75
    acetophenone 602.97
    methyl propionate 722.14
    isopentyl acetate 692.35
    trichloroethylene 3415.85
    n-nonanol 226.68
    cyclohexanol 909.6
    benzyl alcohol 481.04
    2-ethylhexanol 312.31
    isooctanol 214.15
    dipropyl ether 576.91
    1,2-dichlorobenzene 889.94
    ethyl lactate 307.98
    propylene carbonate 1052.16
    n-methylformamide 651.76
    2-pentanol 523.67
    n-pentane 130.81
    1-propoxy-2-propanol 581.84
    1-methoxy-2-propyl acetate 624.53
    2-(2-methoxypropoxy) propanol 427.46
    mesitylene 256.6
    ε-caprolactone 1527.71
    p-cymene 203.15
    epichlorohydrin 1890.73
    1,1,1-trichloroethane 1631.14
    2-aminoethanol 270.45
    morpholine-4-carbaldehyde 1085.43
    sulfolane 1989.76
    2,2,4-trimethylpentane 59.56
    2-methyltetrahydrofuran 1427.35
    n-hexyl acetate 755.16
    isooctane 46.96
    2-(2-butoxyethoxy)ethanol 692.92
    sec-butyl acetate 586.66
    tert-butyl acetate 761.95
    decalin 126.7
    glycerin 255.14
    diglyme 1363.78
    acrylic acid 596.93
    isopropyl myristate 252.99
    n-butyric acid 1455.14
    acetyl acetate 814.59
    di(2-ethylhexyl) phthalate 220.18
    ethyl propionate 725.88
    nitromethane 1737.05
    1,2-diethoxyethane 969.94
    benzonitrile 839.87
    trioctyl phosphate 160.18
    1-bromopropane 1200.02
    gamma-valerolactone 1919.28
    n-decanol 151.64
    triethyl phosphate 272.81
    4-methyl-2-pentanol 306.03
    propionitrile 833.81
    vinylene carbonate 973.84
    1,1,2-trichlorotrifluoroethane 1298.01
    DMS 483.0
    cumene 207.66
    2-octanol 185.27
    2-hexanone 737.65
    octyl acetate 311.1
    limonene 331.0
    1,2-dimethoxyethane 1202.17
    ethyl orthosilicate 260.83
    tributyl phosphate 228.58
    diacetone alcohol 647.8
    N,N-dimethylaniline 337.42
    acrylonitrile 989.01
    aniline 733.75
    1,3-propanediol 513.58
    bromobenzene 1217.57
    dibromomethane 2424.85
    1,1,2,2-tetrachloroethane 2700.73
    2-methyl-cyclohexyl acetate 446.73
    tetrabutyl urea 279.49
    diisobutyl methanol 211.78
    2-phenylethanol 371.67
    styrene 473.59
    dioctyl adipate 398.29
    dimethyl sulfate 429.45
    ethyl butyrate 681.08
    methyl lactate 313.89
    butyl lactate 462.46
    diethyl carbonate 420.58
    propanediol butyl ether 473.02
    triethyl orthoformate 444.02
    p-tert-butyltoluene 180.01
    methyl 4-tert-butylbenzoate 479.43
    morpholine 1584.41
    tert-butylamine 513.07
    n-dodecanol 115.35
    dimethoxymethane 708.1
    ethylene carbonate 916.34
    cyrene 378.69
    2-ethoxyethyl acetate 772.13
    2-ethylhexyl acetate 543.9
    1,2,4-trichlorobenzene 950.84
    4-methylpyridine 1437.99
    dibutyl ether 583.29
    2,6-dimethyl-4-heptanol 211.78
    DEF 1006.54
    dimethyl isosorbide 682.79
    tetrachloroethylene 1971.87
    eugenol 406.06
    triacetin 745.13
    span 80 462.1
    1,4-butanediol 198.76
    1,1-dichloroethane 1904.2
    2-methyl-1-pentanol 419.1
    methyl formate 441.02
    2-methyl-1-butanol 543.03
    n-decane 58.15
    butyronitrile 962.36
    3,7-dimethyl-1-octanol 268.38
    1-chlorooctane 254.82
    1-chlorotetradecane 85.01
    n-nonane 59.43
    undecane 38.27
    tert-butylcyclohexane 95.57
    cyclooctane 110.59
    cyclopentanol 822.41
    tetrahydropyran 1796.07
    tert-amyl methyl ether 491.92
    2,5,8-trioxanonane 798.29
    1-hexene 479.58
    2-isopropoxyethanol 511.66
    2,2,2-trifluoroethanol 338.85
    methyl butyrate 1048.81

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction