16-Hydroxy-10-oxohexadecanoic acid

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  • Identifiers

    CAS number
    53833-25-3

    Molecular formula
    C16H30O4

    SMILES
    C(CCCCC(=O)O)CCCC(=O)CCCCCCO

    Safety labels

  • Odor profile

    Fragrance
    Fatty 35.2%
    Odorless 33.18%
    Savory 27.45%
    Waxy 27.16%
    Oily 26.76%
    Fresh 26.35%
    Milky 24.32%
    Peach 24.08%
    Sweet 23.49%
    Meaty 23.46%

     

    Flavor
    Fatty 46.93%
    Waxy 41.58%
    Fruity 37.77%
    Oily 36.31%
    Cheese 35.64%
    Odorless 28.56%
    Sweet 26.76%
    Mild 26.5%
    Green 26.45%
    Mushroom 25.91%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.1

    pKa est.
    7.05 (neutral)

    Molecular weight
    286.41 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    442°C

    Flash point

    • 212.19 ˚C est.

  • Synonyms

    • 16-Hydroxy-10-oxohexadecanoic acid
    • 10-oxo-16-hydroxyhexadecanoic acid
    • CHEBI:142246
    • RefChem:78992
    • 10-oxo-16-Hydroxyhexadecanoate
    • 16-Hydroxy-10-oxohexadecanoate
    • 53833-25-3
    • SCHEMBL8734659
    • DTXSID601296262
    • 16-hydroxy-10-oxo-hexadecanoic acid
    • 53833-25-3

  • Applications

    16-Hydroxy-10-oxohexadecanoic acid (CAS 53833-25-3) is primarily used as a platform chemical and building block for functionalized fatty-acid derivatives. It can be employed as a functionalized monomer for the production of polyesters and polyurethanes, providing both carboxyl and hydroxyl functionalities in polymer formulations. It also serves as a precursor for coatings and inks through derivatization to specialty resins and resin components. In addition, it may be used to prepare cosmetic and personal-care ingredients as an intermediate for functionalized fatty-acid derivatives, and it can be converted into lubricant- or plasticizer-like derivatives for industrial formulations. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 57.07
    methanol 107.97
    isopropanol 33.52
    water 0.14
    ethyl acetate 13.32
    n-propanol 31.93
    acetone 29.66
    n-butanol 29.41
    acetonitrile 7.02
    DMF 137.65
    toluene 5.86
    isobutanol 23.31
    1,4-dioxane 49.24
    methyl acetate 12.56
    THF 180.85
    2-butanone 21.48
    n-pentanol 30.89
    sec-butanol 22.29
    n-hexane 1.48
    ethylene glycol 12.94
    NMP 176.36
    cyclohexane 2.42
    DMSO 448.34
    n-butyl acetate 28.51
    n-octanol 19.42
    chloroform 32.83
    n-propyl acetate 30.55
    acetic acid 48.77
    dichloromethane 33.46
    cyclohexanone 89.56
    propylene glycol 30.27
    isopropyl acetate 21.85
    DMAc 185.02
    2-ethoxyethanol 98.74
    isopentanol 35.45
    n-heptane 1.14
    ethyl formate 17.43
    1,2-dichloroethane 31.49
    n-hexanol 23.31
    2-methoxyethanol 132.9
    isobutyl acetate 25.7
    tetrachloromethane 5.83
    n-pentyl acetate 32.93
    transcutol 384.56
    n-heptanol 18.73
    ethylbenzene 8.79
    MIBK 35.18
    2-propoxyethanol 83.42
    tert-butanol 56.64
    MTBE 22.45
    2-butoxyethanol 65.4
    propionic acid 30.51
    o-xylene 10.05
    formic acid 35.01
    diethyl ether 11.1
    m-xylene 9.11
    p-xylene 11.12
    chlorobenzene 11.26
    dimethyl carbonate 10.63
    n-octane 0.91
    formamide 51.98
    cyclopentanone 109.67
    2-pentanone 26.39
    anisole 24.26
    cyclopentyl methyl ether 49.01
    gamma-butyrolactone 111.25
    1-methoxy-2-propanol 111.03
    pyridine 30.3
    3-pentanone 15.78
    furfural 98.4
    n-dodecane 0.93
    diethylene glycol 71.43
    diisopropyl ether 6.96
    tert-amyl alcohol 39.06
    acetylacetone 54.05
    n-hexadecane 1.05
    acetophenone 38.79
    methyl propionate 15.76
    isopentyl acetate 36.19
    trichloroethylene 52.17
    n-nonanol 19.26
    cyclohexanol 36.74
    benzyl alcohol 29.37
    2-ethylhexanol 17.47
    isooctanol 18.67
    dipropyl ether 15.67
    1,2-dichlorobenzene 17.07
    ethyl lactate 28.94
    propylene carbonate 57.0
    n-methylformamide 44.46
    2-pentanol 17.86
    n-pentane 0.73
    1-propoxy-2-propanol 62.31
    1-methoxy-2-propyl acetate 49.81
    2-(2-methoxypropoxy) propanol 74.72
    mesitylene 8.25
    ε-caprolactone 82.25
    p-cymene 8.06
    epichlorohydrin 92.65
    1,1,1-trichloroethane 19.0
    2-aminoethanol 40.75
    morpholine-4-carbaldehyde 141.96
    sulfolane 257.69
    2,2,4-trimethylpentane 1.53
    2-methyltetrahydrofuran 63.11
    n-hexyl acetate 41.13
    isooctane 1.17
    2-(2-butoxyethoxy)ethanol 112.17
    sec-butyl acetate 23.82
    tert-butyl acetate 43.65
    decalin 3.17
    glycerin 63.02
    diglyme 198.37
    acrylic acid 26.08
    isopropyl myristate 17.0
    n-butyric acid 51.09
    acetyl acetate 16.17
    di(2-ethylhexyl) phthalate 23.72
    ethyl propionate 21.76
    nitromethane 66.22
    1,2-diethoxyethane 54.3
    benzonitrile 21.89
    trioctyl phosphate 16.4
    1-bromopropane 11.92
    gamma-valerolactone 182.76
    n-decanol 13.21
    triethyl phosphate 21.12
    4-methyl-2-pentanol 18.03
    propionitrile 9.17
    vinylene carbonate 41.33
    1,1,2-trichlorotrifluoroethane 110.18
    DMS 27.07
    cumene 9.09
    2-octanol 13.0
    2-hexanone 34.82
    octyl acetate 20.9
    limonene 11.97
    1,2-dimethoxyethane 131.73
    ethyl orthosilicate 21.62
    tributyl phosphate 21.63
    diacetone alcohol 82.92
    N,N-dimethylaniline 25.33
    acrylonitrile 12.97
    aniline 14.75
    1,3-propanediol 62.31
    bromobenzene 10.3
    dibromomethane 20.38
    1,1,2,2-tetrachloroethane 59.15
    2-methyl-cyclohexyl acetate 36.03
    tetrabutyl urea 34.13
    diisobutyl methanol 13.27
    2-phenylethanol 27.04
    styrene 9.16
    dioctyl adipate 35.63
    dimethyl sulfate 37.04
    ethyl butyrate 25.53
    methyl lactate 32.98
    butyl lactate 43.59
    diethyl carbonate 16.67
    propanediol butyl ether 77.69
    triethyl orthoformate 28.02
    p-tert-butyltoluene 8.13
    methyl 4-tert-butylbenzoate 52.54
    morpholine 92.41
    tert-butylamine 23.97
    n-dodecanol 9.37
    dimethoxymethane 59.82
    ethylene carbonate 34.14
    cyrene 81.52
    2-ethoxyethyl acetate 49.13
    2-ethylhexyl acetate 26.18
    1,2,4-trichlorobenzene 22.43
    4-methylpyridine 28.39
    dibutyl ether 22.21
    2,6-dimethyl-4-heptanol 13.27
    DEF 51.17
    dimethyl isosorbide 123.81
    tetrachloroethylene 38.66
    eugenol 55.8
    triacetin 62.95
    span 80 66.03
    1,4-butanediol 25.84
    1,1-dichloroethane 15.48
    2-methyl-1-pentanol 32.16
    methyl formate 24.07
    2-methyl-1-butanol 26.25
    n-decane 1.73
    butyronitrile 14.1
    3,7-dimethyl-1-octanol 19.99
    1-chlorooctane 9.08
    1-chlorotetradecane 3.46
    n-nonane 1.45
    undecane 1.2
    tert-butylcyclohexane 2.72
    cyclooctane 1.04
    cyclopentanol 43.64
    tetrahydropyran 44.53
    tert-amyl methyl ether 22.46
    2,5,8-trioxanonane 140.39
    1-hexene 6.68
    2-isopropoxyethanol 65.45
    2,2,2-trifluoroethanol 21.52
    methyl butyrate 38.13

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction