1,5-Dihydroxynaphthalene

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  • Identifiers

    CAS number
    83-56-7

    Molecular formula
    C10H8O2

    SMILES
    C1=CC2=C(C=CC=C2O)C(=C1)O

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Phenolic 87.96%
    Medicinal 62.41%
    Smoky 46.77%
    Burnt 41.69%
    Spicy 36.42%
    Sweet 33.27%
    Leathery 30.99%
    Animal 30.82%
    Musty 30.23%
    Woody 30.21%

     

    Flavor
    Bitter 71.46%
    Phenolic 48.08%
    Medicinal 29.2%
    Medical 28.95%
    Phenol 23.45%
    Very strong 23.15%
    Smoke 23.07%
    Mild 23.05%
    Flat 22.87%
    Indole 22.41%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.8

    pKa est.
    10.82 (weak base)

    Molecular weight
    160.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    329°C

    Flash point

    • 183.84 ˚C est.
    • 252 °C
    • 252 °C c.c.

    Solubility expt.

    • Solubility in water, g/100ml at 20 °C: 0.06

  • Synonyms

    • 1,5-DIHYDROXYNAPHTHALENE
    • 83-56-7
    • 1,5-Naphthalenediol
    • Oxidation Base
    • Durafur Developer E
    • CI 76625
    • C.I. 76625
    • DTXSID2052574
    • NSC-7202
    • P25HC23VH6
    • DTXCID9031147
    • RefChem:73484
    • 201-487-4
    • naphthalene-1,5-diol
    • 1,5-Dihydroxy naphthalene
    • 1,5-Dihydroxynapthalene
    • MFCD00003980
    • 1,5-dihydroxynaphtalene
    • NSC 7202
    • EINECS 201-487-4
    • BRN 2044951
    • UNII-P25HC23VH6
    • AI3-16636
    • 1,5-DIHYDROXYNAPHTHALINE
    • 1,5-Naphthalindiol
    • 1.5-naphthalenediol
    • 1,5-dihydroxy-naphthalene
    • EC 201-487-4
    • SCHEMBL28327
    • 4-06-00-06554 (Beilstein Handbook Reference)
    • BIDD:GT0202
    • CHEMBL204658
    • orb2893266
    • SCHEMBL2145668
    • SCHEMBL5031421
    • SCHEMBL6631055
    • SCHEMBL6631223
    • 1,5-NAPHTHOHYDROQUINONE
    • SCHEMBL29351230
    • 1,5-Dihydroxynaphthalene, 97%
    • BDBM36287
    • NSC7202
    • Tox21_303746
    • SBB059460
    • STL290515
    • AKOS005287408
    • EBC-153102
    • FN67456
    • CAS-83-56-7
    • NCGC00357051-01
    • AC-11727
    • AS-12844
    • SY014336
    • CS-0015800
    • D0590
    • NS00005084
    • ST45053928
    • EN300-52581
    • D72512
    • F216672
    • Q19842073
    • F0001-2128
    • Z276600344
    • InChI=1/C10H8O2/c11-9-5-1-3-7-8(9)4-2-6-10(7)12/h1-6,11-12
    • 1,5-Dihydroxynaphthaline; 1,5-Naphthohydroquinone; C.I. 76625; Durafur Developer E; NSC 7202; Oxidation Base
    • 83-56-7

  • Applications

    1,5-Dihydroxynaphthalene (CAS 83-56-7) is primarily used as an organic synthesis intermediate for producing higher-value aromatic compounds. In industry, it serves as a building block for dyes and pigments (naphthalene-based chromophores), for specialty polymers and coatings where its two phenolic OH groups enable crosslinking and functionalization, and as a precursor in the synthesis of naphthoquinone-type derivatives used in pigments and electronic materials. It is also explored as a starting material in pharmaceutical and agrochemical research for constructing functionalized naphthalene scaffolds, and may be evaluated for use in photoinitiators or resin formulations in coatings. The exact applications depend on local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 28.7
    methanol 32.75
    isopropanol 21.94
    water 0.52
    ethyl acetate 38.34
    n-propanol 22.57
    acetone 94.7
    n-butanol 20.92
    acetonitrile 37.23
    DMF 268.67
    toluene 5.41
    isobutanol 14.56
    1,4-dioxane 243.52
    methyl acetate 49.0
    THF 336.38
    2-butanone 60.02
    n-pentanol 21.97
    sec-butanol 16.34
    n-hexane 4.43
    ethylene glycol 11.94
    NMP 103.65
    cyclohexane 1.75
    DMSO 301.46
    n-butyl acetate 54.01
    n-octanol 30.08
    chloroform 37.08
    n-propyl acetate 44.63
    acetic acid 26.95
    dichloromethane 39.5
    cyclohexanone 74.47
    propylene glycol 6.0
    isopropyl acetate 31.77
    DMAc 135.54
    2-ethoxyethanol 61.81
    isopentanol 19.25
    n-heptane 7.49
    ethyl formate 29.9
    1,2-dichloroethane 59.43
    n-hexanol 37.93
    2-methoxyethanol 91.5
    isobutyl acetate 26.29
    tetrachloromethane 13.25
    n-pentyl acetate 43.06
    transcutol 101.63
    n-heptanol 30.69
    ethylbenzene 13.46
    MIBK 38.32
    2-propoxyethanol 87.76
    tert-butanol 39.71
    MTBE 40.01
    2-butoxyethanol 62.91
    propionic acid 18.35
    o-xylene 9.18
    formic acid 12.3
    diethyl ether 48.2
    m-xylene 8.94
    p-xylene 16.98
    chlorobenzene 11.67
    dimethyl carbonate 31.82
    n-octane 6.16
    formamide 42.33
    cyclopentanone 164.88
    2-pentanone 52.53
    anisole 38.58
    cyclopentyl methyl ether 65.31
    gamma-butyrolactone 168.39
    1-methoxy-2-propanol 60.94
    pyridine 49.89
    3-pentanone 39.93
    furfural 83.92
    n-dodecane 4.41
    diethylene glycol 73.39
    diisopropyl ether 16.66
    tert-amyl alcohol 27.08
    acetylacetone 70.29
    n-hexadecane 5.09
    acetophenone 36.65
    methyl propionate 37.72
    isopentyl acetate 41.96
    trichloroethylene 80.86
    n-nonanol 28.64
    cyclohexanol 16.25
    benzyl alcohol 20.11
    2-ethylhexanol 25.65
    isooctanol 24.81
    dipropyl ether 44.9
    1,2-dichlorobenzene 18.24
    ethyl lactate 23.05
    propylene carbonate 52.51
    n-methylformamide 73.8
    2-pentanol 15.8
    n-pentane 2.07
    1-propoxy-2-propanol 55.38
    1-methoxy-2-propyl acetate 51.71
    2-(2-methoxypropoxy) propanol 39.62
    mesitylene 9.15
    ε-caprolactone 64.34
    p-cymene 13.57
    epichlorohydrin 187.21
    1,1,1-trichloroethane 36.45
    2-aminoethanol 17.54
    morpholine-4-carbaldehyde 144.28
    sulfolane 191.95
    2,2,4-trimethylpentane 2.21
    2-methyltetrahydrofuran 106.95
    n-hexyl acetate 53.58
    isooctane 2.52
    2-(2-butoxyethoxy)ethanol 63.84
    sec-butyl acetate 26.7
    tert-butyl acetate 44.73
    decalin 3.88
    glycerin 18.9
    diglyme 142.84
    acrylic acid 16.15
    isopropyl myristate 24.88
    n-butyric acid 29.25
    acetyl acetate 25.94
    di(2-ethylhexyl) phthalate 15.94
    ethyl propionate 36.33
    nitromethane 107.92
    1,2-diethoxyethane 59.03
    benzonitrile 22.52
    trioctyl phosphate 18.13
    1-bromopropane 21.68
    gamma-valerolactone 161.28
    n-decanol 22.74
    triethyl phosphate 24.19
    4-methyl-2-pentanol 13.89
    propionitrile 30.52
    vinylene carbonate 42.56
    1,1,2-trichlorotrifluoroethane 66.25
    DMS 41.82
    cumene 12.8
    2-octanol 24.49
    2-hexanone 55.36
    octyl acetate 30.72
    limonene 16.7
    1,2-dimethoxyethane 165.35
    ethyl orthosilicate 24.12
    tributyl phosphate 18.53
    diacetone alcohol 53.48
    N,N-dimethylaniline 30.72
    acrylonitrile 42.2
    aniline 10.68
    1,3-propanediol 33.42
    bromobenzene 10.76
    dibromomethane 23.67
    1,1,2,2-tetrachloroethane 65.11
    2-methyl-cyclohexyl acetate 30.5
    tetrabutyl urea 28.78
    diisobutyl methanol 19.69
    2-phenylethanol 31.75
    styrene 11.71
    dioctyl adipate 27.62
    dimethyl sulfate 74.02
    ethyl butyrate 36.68
    methyl lactate 23.62
    butyl lactate 27.93
    diethyl carbonate 24.9
    propanediol butyl ether 36.71
    triethyl orthoformate 28.24
    p-tert-butyltoluene 14.04
    methyl 4-tert-butylbenzoate 43.15
    morpholine 167.47
    tert-butylamine 21.36
    n-dodecanol 17.93
    dimethoxymethane 141.15
    ethylene carbonate 39.2
    cyrene 39.51
    2-ethoxyethyl acetate 55.12
    2-ethylhexyl acetate 35.15
    1,2,4-trichlorobenzene 20.71
    4-methylpyridine 33.98
    dibutyl ether 37.91
    2,6-dimethyl-4-heptanol 19.69
    DEF 65.47
    dimethyl isosorbide 81.85
    tetrachloroethylene 51.72
    eugenol 41.72
    triacetin 37.63
    span 80 30.71
    1,4-butanediol 15.52
    1,1-dichloroethane 30.06
    2-methyl-1-pentanol 18.2
    methyl formate 59.86
    2-methyl-1-butanol 15.2
    n-decane 7.68
    butyronitrile 28.26
    3,7-dimethyl-1-octanol 22.45
    1-chlorooctane 23.72
    1-chlorotetradecane 10.68
    n-nonane 7.34
    undecane 5.65
    tert-butylcyclohexane 4.72
    cyclooctane 1.43
    cyclopentanol 30.37
    tetrahydropyran 90.74
    tert-amyl methyl ether 29.8
    2,5,8-trioxanonane 87.08
    1-hexene 15.4
    2-isopropoxyethanol 44.61
    2,2,2-trifluoroethanol 20.95
    methyl butyrate 47.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction