1,4-Piperazinedipropanamine

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  • Identifiers

    CAS number
    7209-38-3

    Molecular formula
    C10H24N4

    SMILES
    C1CN(CCN1CCCN)CCCN

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 86.59%
    Cheesy 50.8%
    Ripe 44.4%
    Odorless 43.28%
    Animal 37.09%
    Meaty 22.32%
    Savory 18.19%
    Popcorn 15.77%
    Cooked 15.11%
    Cooling 15.11%

     

    Flavor
    Odorless 28.45%
    Ammoniacal 23.88%
    Alkaline 21.95%
    Roasted 21.24%
    Bitter 21.05%
    Bland 20.65%
    Sweet-like 20.34%
    Shrimp 19.93%
    Bouillon 19.93%
    Skunky 19.84%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.4

    pKa est.
    7.67 (neutral)

    Molecular weight
    200.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    342°C

    Flash point

    • 159.76 ˚C est.

  • Synonyms

    • 1,4-Bis(3-aminopropyl)piperazine
    • 7209-38-3
    • 1,4-Piperazinedipropanamine
    • 3,3'-(Piperazine-1,4-diyl)bis(propan-1-amine)
    • N,N'-Bis(3-aminopropyl)piperazine
    • 3-[4-(3-aminopropyl)piperazin-1-yl]propan-1-amine
    • Bis(aminopropyl)piperazine
    • 1,4-Di(3-aminopropyl)piperazine
    • CCRIS 8915
    • EINECS 230-589-1
    • MFCD00006161
    • Piperazine, 1,4-bis(3-aminopropyl)-
    • 7GVX6C734B
    • DTXSID8022246
    • DTXCID202246
    • N,N'-Bis(p-aminopropyl)piperazine
    • 1,4-bis(3'-aminopropyl)piperazine
    • 1,4-Bis(3-aminoprop-1-yl)piperazine
    • BIS(3-AMINOPROPYL)PIPERAZINE, 1,4-
    • N,N'-BIS(.GAMMA.-AMINOPROPYL)PIPERAZINE
    • BAPP
    • UNII-7GVX6C734B
    • 3,3'-piperazine-1,4-diyldipropan-1-amine
    • CHEMBL41307
    • SCHEMBL101501
    • BCP30875
    • STR10932
    • Tox21_301407
    • 1,4-bis-(3-aminopropyl)-piperazine
    • AKOS000120347
    • FB75432
    • NCGC00255268-01
    • NCGC00326597-01
    • 7809-38-3
    • 1 pound not4-Bis(3-aminopropyl)piperazine
    • CAS-7209-38-3
    • DB-055608
    • 1,4-Bis(3-aminopropyl)piperazine, >=99%
    • B1041
    • N,N'-BIS(GAMMA-AMINOPROPYL)PIPERAZINE
    • NS00081179
    • EN300-20682
    • 3,3'-(Piperazine-1,4-diyl)dipropan-1-amine
    • A10993
    • 3-[4-(3-Aminopropyl)-1-piperazinyl]propylamine
    • AB01161391-03
    • Q27268267
    • F2191-0282
    • Z104479786
    • 1,4-Piperazinedipropanamine pound>>3,3'-(Piperazine-1,4-diyl)bis(propan-1-amine) pound>>N,N'-Bis(3-aminopropyl)piperazine
    • 230-589-1

  • Applications

    1,4-Piperazinedipropanamine (CAS 7209-38-3) is a diamine with a piperazine core that is commonly used as a curing agent for epoxy resins in coatings and adhesive systems, promoting crosslinking and improved thermal and mechanical properties. It is also employed as a crosslinker or hardener for polyurethane and polyurea systems in coatings, sealants, and elastomeric materials. Because of its two primary amino groups, it often serves as a synthetic building block or intermediate for piperazine-containing compounds in pharmaceutical synthesis. In addition, 1,4-Piperazinedipropanamine can participate in polymer synthesis such as polyamides or other networks, serving as a starting material in R&D for specialty chemicals. In summary, it is a functional curing agent and intermediate with applications in plastics/coatings, polymer development, and pharmaceutical and specialty-chemical research.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 57.74
    methanol 188.47
    isopropanol 15.31
    water 177.56
    ethyl acetate 14.99
    n-propanol 47.46
    acetone 8.48
    n-butanol 29.78
    acetonitrile 14.24
    DMF 54.45
    toluene 3.04
    isobutanol 25.3
    1,4-dioxane 23.25
    methyl acetate 16.02
    THF 34.56
    2-butanone 10.1
    n-pentanol 14.6
    sec-butanol 15.2
    n-hexane 0.68
    ethylene glycol 155.14
    NMP 126.48
    cyclohexane 2.29
    DMSO 150.61
    n-butyl acetate 11.97
    n-octanol 4.75
    chloroform 94.36
    n-propyl acetate 8.82
    acetic acid 383.58
    dichloromethane 77.6
    cyclohexanone 35.36
    propylene glycol 93.53
    isopropyl acetate 6.09
    DMAc 51.23
    2-ethoxyethanol 55.9
    isopentanol 13.96
    n-heptane 1.48
    ethyl formate 46.62
    1,2-dichloroethane 31.03
    n-hexanol 16.42
    2-methoxyethanol 138.53
    isobutyl acetate 5.14
    tetrachloromethane 29.14
    n-pentyl acetate 6.42
    transcutol 57.2
    n-heptanol 9.34
    ethylbenzene 1.36
    MIBK 3.08
    2-propoxyethanol 57.88
    tert-butanol 11.18
    MTBE 3.0
    2-butoxyethanol 34.44
    propionic acid 136.53
    o-xylene 3.51
    formic acid 620.24
    diethyl ether 4.13
    m-xylene 2.65
    p-xylene 2.11
    chlorobenzene 11.5
    dimethyl carbonate 9.8
    n-octane 0.55
    formamide 335.17
    cyclopentanone 48.53
    2-pentanone 6.36
    anisole 3.57
    cyclopentyl methyl ether 13.43
    gamma-butyrolactone 125.93
    1-methoxy-2-propanol 47.36
    pyridine 29.33
    3-pentanone 7.69
    furfural 162.3
    n-dodecane 0.34
    diethylene glycol 99.98
    diisopropyl ether 1.11
    tert-amyl alcohol 12.45
    acetylacetone 11.79
    n-hexadecane 0.36
    acetophenone 8.5
    methyl propionate 17.8
    isopentyl acetate 9.04
    trichloroethylene 73.9
    n-nonanol 4.65
    cyclohexanol 24.98
    benzyl alcohol 16.3
    2-ethylhexanol 8.44
    isooctanol 6.54
    dipropyl ether 5.54
    1,2-dichlorobenzene 15.96
    ethyl lactate 20.7
    propylene carbonate 72.24
    n-methylformamide 119.55
    2-pentanol 7.66
    n-pentane 0.99
    1-propoxy-2-propanol 29.9
    1-methoxy-2-propyl acetate 17.7
    2-(2-methoxypropoxy) propanol 17.44
    mesitylene 1.91
    ε-caprolactone 50.52
    p-cymene 3.59
    epichlorohydrin 67.12
    1,1,1-trichloroethane 23.96
    2-aminoethanol 156.97
    morpholine-4-carbaldehyde 90.69
    sulfolane 218.92
    2,2,4-trimethylpentane 0.74
    2-methyltetrahydrofuran 19.31
    n-hexyl acetate 6.24
    isooctane 0.3
    2-(2-butoxyethoxy)ethanol 27.85
    sec-butyl acetate 4.3
    tert-butyl acetate 5.39
    decalin 0.86
    glycerin 225.08
    diglyme 45.07
    acrylic acid 188.58
    isopropyl myristate 2.29
    n-butyric acid 124.1
    acetyl acetate 18.2
    di(2-ethylhexyl) phthalate 8.49
    ethyl propionate 8.28
    nitromethane 179.41
    1,2-diethoxyethane 7.58
    benzonitrile 14.56
    trioctyl phosphate 6.15
    1-bromopropane 8.81
    gamma-valerolactone 102.0
    n-decanol 3.25
    triethyl phosphate 12.61
    4-methyl-2-pentanol 3.67
    propionitrile 15.62
    vinylene carbonate 80.44
    1,1,2-trichlorotrifluoroethane 227.46
    DMS 10.3
    cumene 1.62
    2-octanol 3.21
    2-hexanone 4.2
    octyl acetate 3.85
    limonene 4.48
    1,2-dimethoxyethane 24.08
    ethyl orthosilicate 11.05
    tributyl phosphate 8.1
    diacetone alcohol 14.22
    N,N-dimethylaniline 3.43
    acrylonitrile 27.68
    aniline 17.83
    1,3-propanediol 120.5
    bromobenzene 8.46
    dibromomethane 38.06
    1,1,2,2-tetrachloroethane 64.92
    2-methyl-cyclohexyl acetate 10.59
    tetrabutyl urea 7.95
    diisobutyl methanol 3.66
    2-phenylethanol 16.54
    styrene 1.77
    dioctyl adipate 5.94
    dimethyl sulfate 35.69
    ethyl butyrate 10.84
    methyl lactate 39.75
    butyl lactate 16.7
    diethyl carbonate 10.34
    propanediol butyl ether 27.13
    triethyl orthoformate 11.69
    p-tert-butyltoluene 3.44
    methyl 4-tert-butylbenzoate 12.42
    morpholine 41.26
    tert-butylamine 5.49
    n-dodecanol 2.42
    dimethoxymethane 15.74
    ethylene carbonate 57.0
    cyrene 39.9
    2-ethoxyethyl acetate 11.05
    2-ethylhexyl acetate 7.79
    1,2,4-trichlorobenzene 22.98
    4-methylpyridine 14.92
    dibutyl ether 2.68
    2,6-dimethyl-4-heptanol 3.66
    DEF 21.8
    dimethyl isosorbide 38.0
    tetrachloroethylene 72.24
    eugenol 17.55
    triacetin 14.15
    span 80 21.43
    1,4-butanediol 48.4
    1,1-dichloroethane 15.91
    2-methyl-1-pentanol 9.88
    methyl formate 78.58
    2-methyl-1-butanol 19.78
    n-decane 0.54
    butyronitrile 12.79
    3,7-dimethyl-1-octanol 4.24
    1-chlorooctane 1.91
    1-chlorotetradecane 0.85
    n-nonane 0.52
    undecane 0.41
    tert-butylcyclohexane 0.68
    cyclooctane 0.92
    cyclopentanol 40.84
    tetrahydropyran 13.65
    tert-amyl methyl ether 3.81
    2,5,8-trioxanonane 32.4
    1-hexene 1.51
    2-isopropoxyethanol 21.9
    2,2,2-trifluoroethanol 242.32
    methyl butyrate 12.6

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction