1,4-Dichlorobenzene

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  • Identifiers

    CAS number
    106-46-7

    Molecular formula
    C6H4Cl2

    SMILES
    C1=CC(=CC=C1Cl)Cl

    Safety labels

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Floral 64.75%
    Sweet 42.86%
    Phenolic 39.29%
    Animal 36.68%
    Woody 35.59%
    Rose 34.87%
    Green 29.16%
    Musty 26.18%
    Fruity 25.95%
    Medicinal 25.21%

    Scent© AI

    Odor threshold>

    • Odor Threshold Low: 0.12 [mmHg]. Odor Threshold High: 15.0 [mmHg]. Detection odor threshold from AIHA (mean = 0.12 ppm)

  • Properties

    XLogP3-AA
    3.4

    Molecular weight
    147.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Melting point expt.

    • 127 °F (NTP, 1992)
    • 53 °C
    • 53.1 °C
    • 52.7 °C
    • 128 °F

    Boiling point

    • 345 °F at 760 mmHg (NTP, 1992)
    • 173.9 °C
    • 174 °C
    • 345 °F

    Flash point est.
    75.33 ˚C

    Flash point expt.

    • 150 °F (NTP, 1992)
    • 66.0 °C (150.8 °F) - closed cup
    • 150 °F (66 °C) (closed cup)
    • 66 °C c.c.
    • 150 °F

    Solubility expt.

    • less than 1 mg/mL at 73 °F (NTP, 1992)
    • In water, 81.3 mg/L at 25 °C
    • Practically insoluble in water
    • Soluble in chloroform, carbon disulfide, benzene, ether, alcohol
    • Miscible with ethanol, acetone, benzene; soluble in ethyl ether, chloroform
    • 0.0813 mg/mL at 25 °C
    • Solubility in water, mg/l at 20 °C: 49 (practically insoluble)
    • 0.008%

  • Synonyms

    • 1,4-DICHLOROBENZENE
    • 106-46-7
    • p-Dichlorobenzene
    • paradichlorobenzene
    • Paracide
    • Paramoth
    • para-Dichlorobenzene
    • Paranuggets
    • Santochlor
    • Paradow
    • Evola
    • Persia-perazol
    • Benzene, 1,4-dichloro-
    • p-Dichlorobenzol
    • p-Chlorophenyl chloride
    • Globol
    • Paradi
    • p-Dichlorbenzol
    • Para crystals
    • Dichlorocide
    • Di-chloricide
    • Paradichlorbenzol
    • p-Diclorobenzene
    • p-Dichloorbenzeen
    • Paradichlorobenzol
    • PDCB
    • 1,4-Dichloorbenzeen
    • 1,4-Dichlor-benzol
    • dichloricide
    • 1,4-Diclorobenzene
    • Benzene, p-dichloro-
    • 1,4-dichloro-benzene
    • Parazene
    • Para-zene
    • RCRA waste number U070
    • 4-Dichlorobenzene
    • Dichlorobenzene, p-
    • RCRA waste number U071
    • RCRA waste number U072
    • Kaydox
    • p-DCB
    • Caswell No. 632
    • NCI-C54955
    • p-Dichlorbenzol [German]
    • 1,4-chlorobenzene
    • p-Dichloorbenzeen [Dutch]
    • Paradichlorbenzol [German]
    • p-Diclorobenzene [Italian]
    • CCRIS 307
    • 1,4-Dichloorbenzeen [Dutch]
    • NSC 36935
    • 1,4-Dichlor-benzol [German]
    • 1,4-Diclorobenzene [Italian]
    • HSDB 523
    • p-Dichlorbenzene
    • p-dichloro-benzene
    • EINECS 203-400-5
    • PDB
    • D149TYB5MK
    • EPA Pesticide Chemical Code 061501
    • Dichlorobenzene, para
    • AI3-0050
    • DTXSID1020431
    • CHEBI:28618
    • 1, 4-Dichlorobenzene
    • AI3-00050
    • MFCD00000604
    • NSC-36935
    • 1,3-Cyclohexadien-5-yne,1,4-dichloro-
    • DTXCID30431
    • P-DICHLOROBENZENE [MI]
    • CHEMBL190982
    • EC 203-400-5
    • PARADICHLOROBENZENE [VANDF]
    • PARADICHLOROBENZENE [MART.]
    • NSC36935
    • 1,4-DICHLOROBENZENE [HSDB]
    • PARADICHLOROBENZENE [WHO-DD]
    • NCGC00094540-01
    • p-Dichlorbenzol (German)
    • p-Dichloorbenzeen (Dutch)
    • Paradichlorbenzol (German)
    • p-Diclorobenzene (Italian)
    • 1,4-Dichloorbenzeen (Dutch)
    • 1,4-Dichlor-benzol (German)
    • 1,4-Diclorobenzene (Italian)
    • PARADICHLOROBENZENE (MART.)
    • 1,4-DICHLOROBENZENE, (SOLID)
    • 1,4-DICHLOROBENZENE, [SOLID]
    • CAS-106-46-7
    • 1,4 dichlorobenzene
    • RCRA waste no. D027
    • RCRA waste no. U072
    • UNII-D149TYB5MK
    • diclorobenzene
    • p-dichlorobenzen
    • para-DCB
    • 1,4dichlorobenzene
    • Benzene,4-dichloro-
    • Caswell No 632
    • 1,4-Dichlor-B
    • Dichlorobenzene, solid
    • Spectrum_001891
    • SpecPlus_000512
    • Benzene, 1,4-dichloro-, radical ion(1-)
    • Spectrum2_001869
    • Spectrum3_000846
    • Spectrum4_000686
    • Spectrum5_002008
    • p-Dichlorbenzol(GERMAN)
    • para-Chlorophenyl chloride
    • p-Dichloorbenzeen(DUTCH)
    • WLN: GR DG
    • p-Diclorobenzene(ITALIAN)
    • Dichlorobenzene, p-, solid
    • SCHEMBL5191
    • BSPBio_002431
    • KBioGR_001151
    • KBioSS_002421
    • SPECTRUM330055
    • 1,4-Dichlorobenzene (MAK)
    • BIDD:ER0278
    • DivK1c_006608
    • Pesticide Code: 061501.
    • SPBio_001718
    • 1, 4-Dichloorbenzeen(DUTCH)
    • 1,4-Dichlor-benzol(GERMAN)
    • 1,4-Diclorobenzene(ITALIAN)

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 13.93
    methanol 11.35
    isopropanol 12.02
    water 0.14
    ethyl acetate 91.55
    n-propanol 14.67
    acetone 109.6
    n-butanol 14.75
    acetonitrile 71.0
    DMF 108.9
    toluene 65.19
    isobutanol 11.01
    1,4-dioxane 164.25
    methyl acetate 134.91
    THF 159.48
    2-butanone 125.38
    n-pentanol 17.26
    sec-butanol 20.22
    n-hexane 6.55
    ethylene glycol 2.89
    NMP 125.43
    cyclohexane 7.35
    DMSO 69.2
    n-butyl acetate 90.01
    n-octanol 17.4
    chloroform 276.31
    n-propyl acetate 90.84
    acetic acid 30.75
    dichloromethane 243.71
    cyclohexanone 110.89
    propylene glycol 4.42
    isopropyl acetate 67.65
    DMAc 217.14
    2-ethoxyethanol 45.69
    isopentanol 16.68
    n-heptane 11.53
    ethyl formate 47.99
    1,2-dichloroethane 123.95
    n-hexanol 18.75
    2-methoxyethanol 39.44
    isobutyl acetate 60.35
    tetrachloromethane 52.72
    n-pentyl acetate 58.35
    transcutol 206.02
    n-heptanol 15.22
    ethylbenzene 66.36
    MIBK 52.01
    2-propoxyethanol 42.26
    tert-butanol 21.11
    MTBE 65.72
    2-butoxyethanol 36.88
    propionic acid 26.57
    o-xylene 63.19
    formic acid 8.78
    diethyl ether 54.05
    m-xylene 47.37
    p-xylene 94.93
    chlorobenzene 84.75
    dimethyl carbonate 40.11
    n-octane 6.12
    formamide 31.75
    cyclopentanone 139.42
    2-pentanone 70.71
    anisole 168.09
    cyclopentyl methyl ether 59.51
    gamma-butyrolactone 149.96
    1-methoxy-2-propanol 33.12
    pyridine 168.74
    3-pentanone 76.18
    furfural 181.23
    n-dodecane 5.0
    diethylene glycol 20.94
    diisopropyl ether 28.61
    tert-amyl alcohol 30.7
    acetylacetone 137.67
    n-hexadecane 5.85
    acetophenone 168.26
    methyl propionate 63.21
    isopentyl acetate 82.66
    trichloroethylene 382.76
    n-nonanol 18.51
    cyclohexanol 17.68
    benzyl alcohol 52.66
    2-ethylhexanol 24.71
    isooctanol 16.37
    dipropyl ether 55.97
    1,2-dichlorobenzene 110.62
    ethyl lactate 27.94
    propylene carbonate 88.05
    n-methylformamide 41.02
    2-pentanol 15.74
    n-pentane 4.31
    1-propoxy-2-propanol 38.88
    1-methoxy-2-propyl acetate 95.14
    2-(2-methoxypropoxy) propanol 73.83
    mesitylene 35.54
    ε-caprolactone 109.24
    p-cymene 46.33
    epichlorohydrin 193.26
    1,1,1-trichloroethane 205.57
    2-aminoethanol 6.73
    morpholine-4-carbaldehyde 174.32
    sulfolane 123.43
    2,2,4-trimethylpentane 6.89
    2-methyltetrahydrofuran 114.5
    n-hexyl acetate 63.7
    isooctane 4.42
    2-(2-butoxyethoxy)ethanol 68.54
    sec-butyl acetate 77.89
    tert-butyl acetate 89.47
    decalin 12.53
    glycerin 7.99
    diglyme 196.28
    acrylic acid 27.34
    isopropyl myristate 39.29
    n-butyric acid 30.97
    acetyl acetate 95.59
    di(2-ethylhexyl) phthalate 31.45
    ethyl propionate 75.53
    nitromethane 133.62
    1,2-diethoxyethane 148.07
    benzonitrile 87.67
    trioctyl phosphate 17.2
    1-bromopropane 63.68
    gamma-valerolactone 199.77
    n-decanol 14.69
    triethyl phosphate 59.08
    4-methyl-2-pentanol 14.15
    propionitrile 43.39
    vinylene carbonate 93.33
    1,1,2-trichlorotrifluoroethane 116.25
    DMS 95.03
    cumene 45.18
    2-octanol 14.66
    2-hexanone 97.36
    octyl acetate 38.68
    limonene 52.25
    1,2-dimethoxyethane 163.96
    ethyl orthosilicate 57.49
    tributyl phosphate 28.12
    diacetone alcohol 57.87
    N,N-dimethylaniline 111.77
    acrylonitrile 65.58
    aniline 46.53
    1,3-propanediol 12.19
    bromobenzene 113.22
    dibromomethane 135.27
    1,1,2,2-tetrachloroethane 243.22
    2-methyl-cyclohexyl acetate 85.51
    tetrabutyl urea 39.74
    diisobutyl methanol 24.45
    2-phenylethanol 51.16
    styrene 77.78
    dioctyl adipate 61.62
    dimethyl sulfate 76.9
    ethyl butyrate 94.1
    methyl lactate 22.73
    butyl lactate 33.65
    diethyl carbonate 71.67
    propanediol butyl ether 27.04
    triethyl orthoformate 74.31
    p-tert-butyltoluene 46.06
    methyl 4-tert-butylbenzoate 81.95
    morpholine 123.15
    tert-butylamine 15.51
    n-dodecanol 12.49
    dimethoxymethane 67.37
    ethylene carbonate 60.25
    cyrene 76.31
    2-ethoxyethyl acetate 106.55
    2-ethylhexyl acetate 84.46
    1,2,4-trichlorobenzene 160.08
    4-methylpyridine 146.82
    dibutyl ether 60.05
    2,6-dimethyl-4-heptanol 24.45
    DEF 92.37
    dimethyl isosorbide 186.5
    tetrachloroethylene 153.97
    eugenol 74.83
    triacetin 109.67
    span 80 46.32
    1,4-butanediol 6.89
    1,1-dichloroethane 119.49
    2-methyl-1-pentanol 24.52
    methyl formate 38.23
    2-methyl-1-butanol 16.83
    n-decane 7.78
    butyronitrile 38.3
    3,7-dimethyl-1-octanol 25.58
    1-chlorooctane 26.4
    1-chlorotetradecane 13.05
    n-nonane 7.09
    undecane 5.95
    tert-butylcyclohexane 13.5
    cyclooctane 5.25
    cyclopentanol 20.28
    tetrahydropyran 89.45
    tert-amyl methyl ether 64.5
    2,5,8-trioxanonane 149.86
    1-hexene 22.37
    2-isopropoxyethanol 42.41
    2,2,2-trifluoroethanol 21.84
    methyl butyrate 93.26

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction