1,4-Cyclohexanedimethanol

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  • Identifiers

    CAS number
    105-08-8

    Molecular formula
    C8H16O2

    SMILES
    C1CC(CCC1CO)CO

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fermented 46.47%
    Alcoholic 45.04%
    Oily 42.34%
    Solvent 40.88%
    Fruity 36.94%
    Ethereal 35.88%
    Sweet 35.15%
    Mint 28.85%
    Fishy 28.57%
    Floral 28.13%

     

    Flavor
    Sweet 29.36%
    Fruit 28.33%
    Musty 26.24%
    Odorless 26.06%
    Bitter 25.91%
    Cauliflower 25.22%
    Caramel 25.2%
    Oily 24.26%
    Alkaline 22.85%
    Very slight 22.63%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    8.69 (weak base)

    Molecular weight
    144.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 43 °C (cis-isomer), 67 °C (trans-isomer)

    Boiling point

    • 286 °C (cis-isomer), 283 °C (trans-isomer)

    Flash point

    • 138.32 ˚C est.
    • 166 °C
    • 330 °F OC

    Solubility expt.

    • In water, 920,000 mg/L at 20 °C
    • Solluble in ethyl alcohol

  • Synonyms

    • 1,4-CYCLOHEXANEDIMETHANOL
    • 105-08-8
    • [4-(hydroxymethyl)cyclohexyl]methanol
    • 1,4-Bis(hydroxymethyl)cyclohexane
    • CHDM
    • 1,4-Chidm
    • Cyclohexane-1,4-dimethanol
    • Rikabinol DM
    • 1,4-Dimethylolcyclohexane
    • Cyclohex-1,4-ylenedimethanol
    • 1,4-Cyclohexamethylenebis methylol
    • DTXSID9026712
    • 8C3FKR6R1B
    • DTXCID106712
    • NSC-44508
    • (4-(hydroxymethyl)cyclohexyl)methanol
    • RefChem:6712
    • EASTMAN VERITYL AB-1000 DIOL
    • 203-268-9
    • 692-674-3
    • trans-1,4-Cyclohexanedimethanol
    • 3236-48-4
    • 3236-47-3
    • cis-1,4-Cyclohexanedimethanol
    • 1,4-Cyclohexanedimethanol, cis-
    • 1,4-Cyclohexanedimethanol, trans-
    • trans-cyclohexane-1,4-diyldimethanol
    • MFCD00066360
    • trans-1,4-Bis(hydroxymethyl)cyclohexane
    • cis-cyclohexane-1,4-diyldimethanol
    • trans-[4-(hydroxymethyl)cyclohexyl]methanol
    • MFCD00064957
    • 1,4-cyclohexane dimethanol
    • (trans-4-Hydroxymethylcyclohexyl)methanol
    • cis-[4-(hydroxymethyl)cyclohexyl]methanol
    • trans-(4-hydroxymethyl-cyclohexyl)-methanol
    • 47A69Y3G5M
    • cis-1,4-bis(hydroxymethyl)cyclohexane
    • 7I8476P8P0
    • cis-(cyclohexane-1,4-diyl)dimethanol
    • PM 1597
    • cis-CHDM
    • [4-(hydroxymethyl)cyclohexyl]methan-1-ol
    • HSDB 5364
    • EINECS 203-268-9
    • [(1r,4r)-4-(hydroxymethyl)cyclohexyl]methanol
    • MFCD00001512
    • NSC 44508
    • UNII-8C3FKR6R1B
    • BRN 1902271
    • UNII-47A69Y3G5M
    • AI3-28853
    • UNII-7I8476P8P0
    • (trans-4-Hydroxymethylcyclohexyl)methanol; trans-1,4-Bis(hydroxymethyl)cyclohexane;
    • trans-CHDM
    • (Cyclohexane-1,4-diyl)dimethanol
    • 1,4-Cyclohexanedimethanol, (Z)-
    • CHDM, trans isomer
    • CHDM, cis
    • EC-No. 203-268-9
    • AI3-26300
    • 1,4 cyclohexanedimethanol
    • 1,4 cyclohexane dimethanol
    • 1,4-cyclo-hexanedimethanol
    • 1,4-cyclohexane-dimethanol
    • EC 203-268-9
    • A1IH8
    • SCHEMBL27912
    • SCHEMBL130642
    • SCHEMBL297828
    • 1,4-dihydroxymethylcyclohexane
    • 1,4-Cyclohexanedimethanol,c&t
    • cyclohexane-1,4-diyldimethanol
    • WLN: L6TJ A1Q D1Q
    • (Z)-1,4-cyclohexanedimethanol
    • SCHEMBL1316560
    • SCHEMBL6113181
    • SCHEMBL6434055
    • 1,4-Cyclohexanedimethanol, cis
    • CHEMBL3185118
    • Cyclohexane-1,4-dimethanol,c&t
    • SCHEMBL11682560
    • SCHEMBL11723676
    • 1,4-Cyclohexanedimethanol, trans
    • DTXSID00274143
    • DTXSID60274144
    • trans-1,4-cyclohexane dimethanol
    • trans-cyclohexane-1,4-dimethanol
    • (4-Hydroxymethylcyclohexyl)methanol
    • NSC44508
    • Tox21_200433
    • trans-1,4-dihydroxymethylcyclohexane
    • 1,4-bis-(hydroxymethyl)-cyclohexane
    • AC-291
    • Cyclohex-1,4-ylenedimethanol, trans
    • MSK161335
    • SBB058762
    • AKOS009031609
    • AKOS015833096
    • AKOS028109404
    • 1,4-Bis(hydroxymethyl)cyclohexane,c&t
    • AT36023
    • CS-W016379
    • EAN 087583
    • MSK161335-100M
    • SB17942
    • 1,4-Cyclohexanedimethanol, cis + trans
    • MSK161335-1000M
    • NCGC00248612-01
    • NCGC00257987-01
    • AS-18294
    • CAS-105-08-8
    • SY024459
    • SY342154
    • [(1r,4r)-Cyclohexane-1,4-diyl]dimethanol
    • [(1s,4s)-Cyclohexane-1,4-diyl]dimethanol
    • DB-026925
    • C2234
    • NS00007618
    • ST50823930
    • EN300-19999
    • alpha,alpha'-Dihydroxy-1,4-dimethylcyclohexane
    • F87287
    • EN300-1721997
    • F093287
    • F791415
    • Q1064929
    • 105-08-8

  • Applications

    1,4-Cyclohexanedimethanol (CAS 105-08-8) is commonly used as a diol monomer/chain extender in the production of polyesters and polyurethanes. In polyester resins, it improves thermal stability, chemical resistance, and optical clarity, making it suitable for high-performance packaging films and specialty molded parts. In polyurethane systems, it serves as a diol crosslinker/chain extender to enhance hardness, heat resistance, and abrasion performance in coatings, sealants, and elastomeric foams. It is also used in UV-curable coatings and reactive resins for inks and coatings, and as a building block in specialty adhesives for electronics, automotive, and industrial applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 249.02
    methanol 379.02
    isopropanol 156.83
    water 5.25
    ethyl acetate 74.72
    n-propanol 240.95
    acetone 86.29
    n-butanol 228.27
    acetonitrile 58.56
    DMF 103.92
    toluene 16.53
    isobutanol 134.66
    1,4-dioxane 157.75
    methyl acetate 63.03
    THF 326.17
    2-butanone 75.68
    n-pentanol 70.42
    sec-butanol 113.05
    n-hexane 6.35
    ethylene glycol 95.79
    NMP 225.73
    cyclohexane 17.53
    DMSO 488.53
    n-butyl acetate 86.2
    n-octanol 38.68
    chloroform 239.35
    n-propyl acetate 51.58
    acetic acid 316.79
    dichloromethane 199.68
    cyclohexanone 207.16
    propylene glycol 107.65
    isopropyl acetate 41.33
    DMAc 58.81
    2-ethoxyethanol 116.65
    isopentanol 130.75
    n-heptane 10.56
    ethyl formate 113.93
    1,2-dichloroethane 129.19
    n-hexanol 97.48
    2-methoxyethanol 303.59
    isobutyl acetate 27.62
    tetrachloromethane 71.9
    n-pentyl acetate 50.08
    transcutol 321.31
    n-heptanol 57.11
    ethylbenzene 10.49
    MIBK 39.21
    2-propoxyethanol 152.35
    tert-butanol 161.67
    MTBE 40.13
    2-butoxyethanol 111.05
    propionic acid 248.0
    o-xylene 16.68
    formic acid 200.43
    diethyl ether 47.71
    m-xylene 15.68
    p-xylene 13.53
    chlorobenzene 53.88
    dimethyl carbonate 23.44
    n-octane 3.87
    formamide 262.62
    cyclopentanone 322.7
    2-pentanone 73.85
    anisole 28.7
    cyclopentyl methyl ether 110.22
    gamma-butyrolactone 466.79
    1-methoxy-2-propanol 173.36
    pyridine 130.74
    3-pentanone 44.91
    furfural 331.45
    n-dodecane 2.21
    diethylene glycol 137.16
    diisopropyl ether 14.49
    tert-amyl alcohol 99.84
    acetylacetone 73.74
    n-hexadecane 2.46
    acetophenone 41.5
    methyl propionate 60.35
    isopentyl acetate 68.39
    trichloroethylene 271.18
    n-nonanol 32.99
    cyclohexanol 143.43
    benzyl alcohol 44.13
    2-ethylhexanol 48.97
    isooctanol 43.4
    dipropyl ether 46.4
    1,2-dichlorobenzene 64.76
    ethyl lactate 42.01
    propylene carbonate 214.17
    n-methylformamide 209.01
    2-pentanol 87.73
    n-pentane 8.96
    1-propoxy-2-propanol 112.32
    1-methoxy-2-propyl acetate 73.15
    2-(2-methoxypropoxy) propanol 65.73
    mesitylene 13.53
    ε-caprolactone 195.86
    p-cymene 18.18
    epichlorohydrin 276.07
    1,1,1-trichloroethane 107.11
    2-aminoethanol 185.32
    morpholine-4-carbaldehyde 171.81
    sulfolane 594.67
    2,2,4-trimethylpentane 5.31
    2-methyltetrahydrofuran 189.23
    n-hexyl acetate 61.16
    isooctane 4.54
    2-(2-butoxyethoxy)ethanol 110.1
    sec-butyl acetate 27.07
    tert-butyl acetate 49.67
    decalin 6.05
    glycerin 180.01
    diglyme 190.8
    acrylic acid 225.9
    isopropyl myristate 19.8
    n-butyric acid 306.54
    acetyl acetate 49.95
    di(2-ethylhexyl) phthalate 30.38
    ethyl propionate 40.38
    nitromethane 280.69
    1,2-diethoxyethane 62.45
    benzonitrile 58.78
    trioctyl phosphate 26.96
    1-bromopropane 54.97
    gamma-valerolactone 323.71
    n-decanol 22.63
    triethyl phosphate 35.64
    4-methyl-2-pentanol 40.13
    propionitrile 77.43
    vinylene carbonate 154.44
    1,1,2-trichlorotrifluoroethane 283.92
    DMS 39.52
    cumene 10.3
    2-octanol 29.75
    2-hexanone 39.89
    octyl acetate 27.77
    limonene 28.15
    1,2-dimethoxyethane 114.38
    ethyl orthosilicate 33.83
    tributyl phosphate 31.47
    diacetone alcohol 95.61
    N,N-dimethylaniline 22.01
    acrylonitrile 104.27
    aniline 67.64
    1,3-propanediol 289.02
    bromobenzene 42.82
    dibromomethane 128.11
    1,1,2,2-tetrachloroethane 223.49
    2-methyl-cyclohexyl acetate 51.7
    tetrabutyl urea 33.47
    diisobutyl methanol 32.68
    2-phenylethanol 56.37
    styrene 12.56
    dioctyl adipate 34.47
    dimethyl sulfate 63.37
    ethyl butyrate 62.12
    methyl lactate 62.14
    butyl lactate 66.25
    diethyl carbonate 39.46
    propanediol butyl ether 93.77
    triethyl orthoformate 47.46
    p-tert-butyltoluene 18.91
    methyl 4-tert-butylbenzoate 65.51
    morpholine 219.5
    tert-butylamine 86.62
    n-dodecanol 16.0
    dimethoxymethane 70.19
    ethylene carbonate 132.91
    cyrene 85.71
    2-ethoxyethyl acetate 63.76
    2-ethylhexyl acetate 51.93
    1,2,4-trichlorobenzene 74.24
    4-methylpyridine 69.86
    dibutyl ether 30.03
    2,6-dimethyl-4-heptanol 32.68
    DEF 72.72
    dimethyl isosorbide 134.96
    tetrachloroethylene 208.93
    eugenol 62.61
    triacetin 63.34
    span 80 78.18
    1,4-butanediol 66.24
    1,1-dichloroethane 84.79
    2-methyl-1-pentanol 45.95
    methyl formate 124.7
    2-methyl-1-butanol 111.14
    n-decane 4.11
    butyronitrile 83.5
    3,7-dimethyl-1-octanol 35.48
    1-chlorooctane 18.37
    1-chlorotetradecane 6.0
    n-nonane 4.11
    undecane 2.87
    tert-butylcyclohexane 5.71
    cyclooctane 6.02
    cyclopentanol 221.86
    tetrahydropyran 154.95
    tert-amyl methyl ether 32.87
    2,5,8-trioxanonane 118.55
    1-hexene 16.39
    2-isopropoxyethanol 61.7
    2,2,2-trifluoroethanol 165.75
    methyl butyrate 65.57

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction