1,3-Dioxolane

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  • Identifiers

    CAS number
    646-06-0

    Molecular formula
    C3H6O2

    SMILES
    C1COCO1

    Safety labels

    Flammable
    Flammable

  • Odor profile

    sweet 70.85%
    ethereal 63.32%
    fruity 42.11%
    solvent 37.53%
    alcoholic 31.27%
    pungent 29.19%
    fermented 29.09%
    rummy 28.02%
    green 26.82%
    musty 25.56%

    Scent© AI

  • Properties

    XLogP3-AA
    -0.4 Well soluble in DPG, ETH, PG

    Molecular weight
    74.08 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -95 °C

    Boiling point

    • 78 °C

    Flash point expt.

    • 35 °F (2 °C) (Open cup)

    Solubility expt.

    • Soluble in ethanol, ether, acetone
    • Miscible in water

  • Synonyms

    • 1,3-DIOXOLANE
    • 646-06-0
    • DIOXOLANE
    • Glycolformal
    • Formal glycol
    • 1,3-Dioxacyclopentane
    • 1,3-Dioxolan
    • Dioxolan
    • 1,3-Dioxolane, Stabilized
    • Glycol formal
    • Ethylene glycol formal
    • Glycol methylene ether
    • Dioxolan [Czech]
    • 1,3-Dioxole, dihydro-
    • 1,3-Dioxlane
    • Dioxolane, 1,3-
    • 5-Crown-2
    • CCRIS 4912
    • HSDB 5737
    • UNII-Y57RBG19JL
    • EINECS 211-463-5
    • 1,3-Dioxolane (stabilized with BHT)
    • DTXSID4027284
    • CHEBI:87597
    • ELCOTAL DX
    • Y57RBG19JL
    • DTXCID107284
    • 1,3-DIOXOLANE [HSDB]
    • EC 211-463-5
    • 1,3-dioxalane
    • MFCD00003207
    • UN1166
    • Formaldehyde ethylene acetal
    • Ethylene glycol methylene ether
    • 1,3 dioxolane
    • 1,3Dioxolan
    • 1,4-dioxolane
    • [1,3]dioxolane
    • [1,3]-dioxolane
    • 1,3Dioxacyclopentane
    • dihydro-1,3-dioxole
    • 1,3Dioxole, dihydro
    • Ethylene glycol, formal
    • DIOXOLANE [INCI]
    • CHEMBL3187281
    • CHEBI:39430
    • 1,3-Dioxolane, >=99.5%
    • Tox21_300693
    • AKOS015856096
    • FD54839
    • NCGC00248143-01
    • NCGC00254601-01
    • CAS-646-06-0
    • Dioxolane [UN1166] [Flammable liquid]
    • D0861
    • D5539
    • NS00004542
    • 1,3-Dioxolane 100 microg/mL in Acetonitrile
    • 1,3-Dioxolane;Ethylene glycol methylene ether
    • D89731
    • A834826
    • Q2234483
    • 1,3-Dioxlane, 99.5%, contains ~75 ppm BHT as stabilizer
    • 1,3-Dioxacyclopentane,Anhydrous, Contains ~ 75 ppm BHT as inhibitor.
    • 1,3-Dioxolane, anhydrous, contains ~75 ppm BHT as inhibitor, 99.8%
    • 1,3-Dioxolane, ReagentPlus(R), contains ~75 ppm BHT as inhibitor, 99%
    • 1,3-Dioxlane, 99.8%,with molecular sieves, stabilized with BHT, Water
    • 25067-64-5
1 4

IFRA Standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction