1,3-Dichloro-1,1,2,2,3-pentafluoropropane

Overview IFRA Request a quote

  • Identifiers

    CAS number
    507-55-1

    Molecular formula
    C3HCl2F5

    SMILES
    C(C(C(F)(F)Cl)(F)F)(F)Cl

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 57.29%
    Fishy 26.72%
    Sweet 23.16%
    Woody 21.96%
    Cooling 21.1%
    Balsamic 17.24%
    Animal 16.09%
    Savory 15.39%
    Mint 15.07%
    Dry 14.76%

     

    Flavor
    Odorless 32.41%
    Bland 21.54%
    Sulfurous 21.03%
    Mild 18.15%
    Sweet-like 17.83%
    Bitter 17.72%
    Bloody 17.71%
    Glue 17.58%
    Bouillon 17.36%
    Skunky 17.06%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.4

    pKa est.
    4.21 (weak acid)

    Molecular weight
    202.93 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -97 °C

    Boiling point

    • 56.1 °C

    Flash point

    • 2.01 ˚C est.

  • Synonyms

    • 1,3-Dichloro-1,1,2,2,3-pentafluoropropane
    • HCFC-225cb
    • 507-55-1
    • HCFC 225cb
    • Propane, 1,3-dichloro-1,1,2,2,3-pentafluoro-
    • HSDB 6977
    • EINECS 208-076-9
    • UNII-G6975BUY8I
    • CCRIS 8667
    • G6975BUY8I
    • ASAHIKLIN AK 225G
    • HFC-225BC
    • AK-225CB
    • DTXSID6042028
    • AK-225G
    • R-225CB
    • R-225A
    • 1,1,2,2,3-pentafluoro-1,3-dichloropropane
    • HCFC 225bc
    • R 225cb
    • R 225a
    • 1,3-DICHLORO-1,2,2,3,3-PENTAFLUOROPROPANE
    • ClCF2CF2CHClF
    • SCHEMBL64666
    • DTXCID4022028
    • 1,3Dichloro1,2,2,3,3pentafluoropropane
    • Dichloropentafluoropropanes (HCFC-225ca/cb)
    • NS00043484
    • Propane, 1,3dichloro1,1,2,2,3pentafluoro
    • 1,3-Dichloro-1,1,2,2,3-pentafluoropropane #
    • 1,3-DICHLORO-1,1,1,2,3-PENTAFLUOROPROPANE
    • Q27278838
    • 1,3-DICHLORO-1,2,2,3,3-PENTAFLUOROPROPANE [HSDB]
    • 208-076-9

  • Applications

    1,3-Dichloro-1,1,2,2,3-pentafluoropropane (CAS 507-55-1) is used as an intermediate in the synthesis of fluorinated specialty chemicals and may also function as a solvent or processing aid in polymer and coating manufacturing. It can serve as a precursor for fluorinated plastics and as a cleaning or surface-prep solvent in electronics manufacturing. In adhesive and coating formulations, it may act as a reactive diluent or solvent component, depending on formulation and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 299.35
    methanol 562.06
    isopropanol 179.38
    water 75.29
    ethyl acetate 164.29
    n-propanol 183.62
    acetone 523.5
    n-butanol 138.79
    acetonitrile 317.99
    DMF 1122.11
    toluene 76.68
    isobutanol 122.89
    1,4-dioxane 282.67
    methyl acetate 205.15
    THF 460.35
    2-butanone 283.94
    n-pentanol 133.76
    sec-butanol 155.05
    n-hexane 29.07
    ethylene glycol 165.13
    NMP 841.75
    cyclohexane 58.54
    DMSO 1885.8
    n-butyl acetate 84.54
    n-octanol 86.65
    chloroform 108.92
    n-propyl acetate 130.98
    acetic acid 202.76
    dichloromethane 195.39
    cyclohexanone 247.53
    propylene glycol 88.31
    isopropyl acetate 109.7
    DMAc 991.07
    2-ethoxyethanol 400.49
    isopentanol 118.98
    n-heptane 43.49
    ethyl formate 141.06
    1,2-dichloroethane 191.0
    n-hexanol 85.02
    2-methoxyethanol 516.24
    isobutyl acetate 52.82
    tetrachloromethane 24.93
    n-pentyl acetate 70.72
    transcutol 594.53
    n-heptanol 61.59
    ethylbenzene 53.43
    MIBK 138.55
    2-propoxyethanol 211.69
    tert-butanol 185.11
    MTBE 158.91
    2-butoxyethanol 133.49
    propionic acid 107.12
    o-xylene 90.94
    formic acid 264.9
    diethyl ether 234.7
    m-xylene 63.25
    p-xylene 56.31
    chlorobenzene 36.76
    dimethyl carbonate 133.92
    n-octane 20.36
    formamide 586.04
    cyclopentanone 317.63
    2-pentanone 234.62
    anisole 141.02
    cyclopentyl methyl ether 227.59
    gamma-butyrolactone 289.71
    1-methoxy-2-propanol 326.32
    pyridine 229.65
    3-pentanone 207.03
    furfural 278.46
    n-dodecane 13.83
    diethylene glycol 227.0
    diisopropyl ether 75.23
    tert-amyl alcohol 164.89
    acetylacetone 268.05
    n-hexadecane 14.88
    acetophenone 174.35
    methyl propionate 193.54
    isopentyl acetate 59.72
    trichloroethylene 185.78
    n-nonanol 79.83
    cyclohexanol 140.56
    benzyl alcohol 126.21
    2-ethylhexanol 59.61
    isooctanol 49.52
    dipropyl ether 127.29
    1,2-dichlorobenzene 36.96
    ethyl lactate 102.95
    propylene carbonate 104.9
    n-methylformamide 490.43
    2-pentanol 119.63
    n-pentane 53.44
    1-propoxy-2-propanol 152.09
    1-methoxy-2-propyl acetate 124.35
    2-(2-methoxypropoxy) propanol 180.62
    mesitylene 49.88
    ε-caprolactone 184.0
    p-cymene 50.45
    epichlorohydrin 292.71
    1,1,1-trichloroethane 69.2
    2-aminoethanol 195.67
    morpholine-4-carbaldehyde 624.36
    sulfolane 490.04
    2,2,4-trimethylpentane 20.75
    2-methyltetrahydrofuran 263.29
    n-hexyl acetate 90.84
    isooctane 12.41
    2-(2-butoxyethoxy)ethanol 216.93
    sec-butyl acetate 76.4
    tert-butyl acetate 110.34
    decalin 19.76
    glycerin 145.83
    diglyme 407.15
    acrylic acid 118.67
    isopropyl myristate 50.03
    n-butyric acid 99.13
    acetyl acetate 96.77
    di(2-ethylhexyl) phthalate 42.12
    ethyl propionate 124.03
    nitromethane 573.17
    1,2-diethoxyethane 188.64
    benzonitrile 97.26
    trioctyl phosphate 35.85
    1-bromopropane 122.38
    gamma-valerolactone 382.97
    n-decanol 62.77
    triethyl phosphate 54.56
    4-methyl-2-pentanol 74.21
    propionitrile 172.79
    vinylene carbonate 94.43
    1,1,2-trichlorotrifluoroethane 210.11
    DMS 88.28
    cumene 42.2
    2-octanol 53.91
    2-hexanone 159.41
    octyl acetate 62.9
    limonene 79.46
    1,2-dimethoxyethane 552.32
    ethyl orthosilicate 50.77
    tributyl phosphate 40.25
    diacetone alcohol 182.6
    N,N-dimethylaniline 174.36
    acrylonitrile 214.71
    aniline 111.87
    1,3-propanediol 188.11
    bromobenzene 31.48
    dibromomethane 140.73
    1,1,2,2-tetrachloroethane 152.37
    2-methyl-cyclohexyl acetate 70.4
    tetrabutyl urea 99.61
    diisobutyl methanol 47.85
    2-phenylethanol 84.02
    styrene 61.95
    dioctyl adipate 76.94
    dimethyl sulfate 241.48
    ethyl butyrate 98.83
    methyl lactate 146.33
    butyl lactate 72.25
    diethyl carbonate 61.01
    propanediol butyl ether 127.48
    triethyl orthoformate 72.75
    p-tert-butyltoluene 45.39
    methyl 4-tert-butylbenzoate 126.86
    morpholine 389.59
    tert-butylamine 128.68
    n-dodecanol 49.76
    dimethoxymethane 517.57
    ethylene carbonate 83.5
    cyrene 200.34
    2-ethoxyethyl acetate 101.69
    2-ethylhexyl acetate 50.29
    1,2,4-trichlorobenzene 48.8
    4-methylpyridine 209.78
    dibutyl ether 92.22
    2,6-dimethyl-4-heptanol 47.85
    DEF 385.36
    dimethyl isosorbide 236.41
    tetrachloroethylene 114.62
    eugenol 123.57
    triacetin 115.76
    span 80 106.2
    1,4-butanediol 124.11
    1,1-dichloroethane 105.16
    2-methyl-1-pentanol 101.78
    methyl formate 328.36
    2-methyl-1-butanol 120.12
    n-decane 23.35
    butyronitrile 139.76
    3,7-dimethyl-1-octanol 69.43
    1-chlorooctane 47.95
    1-chlorotetradecane 23.79
    n-nonane 23.62
    undecane 17.67
    tert-butylcyclohexane 14.02
    cyclooctane 28.69
    cyclopentanol 149.92
    tetrahydropyran 210.0
    tert-amyl methyl ether 160.22
    2,5,8-trioxanonane 325.13
    1-hexene 64.33
    2-isopropoxyethanol 232.95
    2,2,2-trifluoroethanol 127.18
    methyl butyrate 158.59

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction