1,3-Bis(2-hydroxyethoxy)benzene

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  • Identifiers

    CAS number
    102-40-9

    Molecular formula
    C10H14O4

    SMILES
    C1=CC(=CC(=C1)OCCO)OCCO

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Floral 37.77%
    Odorless 35.56%
    Balsamic 33.52%
    Sweet 33.26%
    Fresh 26.7%
    Rose 26.29%
    Fruity 25.17%
    Powdery 22.32%
    Vanilla 22.11%
    Animal 22.11%

     

    Flavor
    Sweet 52.6%
    Bitter 48.39%
    Fruity 40.71%
    Creamy 36.09%
    Floral 33.29%
    Mild 33.06%
    Musty 29.79%
    Balsam 28.41%
    Vanilla 26.06%
    Rose 25.08%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.4

    pKa est.
    7.87 (neutral)

    Molecular weight
    198.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    430°C

    Flash point

    • 189.93 ˚C est.

  • Synonyms

    • 1,3-Bis(2-hydroxyethoxy)benzene
    • 102-40-9
    • 2,2'-(m-Phenylenedioxy)diethanol
    • m-Bis(2-hydroxyethoxy)benzene
    • resorcinol bis(2-hydroxyethyl) ether
    • Ethanol, 2,2'-[1,3-phenylenebis(oxy)]bis-
    • Resorcinol bis(beta-hydroxyethyl) ether
    • G4SGN7D66B
    • Ethanol, 2,2'-(m-phenylenedioxy)di-
    • 1,3-di(2-hydroxyethoxy)benzene
    • Resorcinol bis(.beta.-hydroxyethyl) ether
    • Ethanol, 2,2'-(1,3-phenylenebis(oxy))bis-
    • EINECS 203-028-3
    • NSC 65613
    • NSC-65613
    • m-di(2-hydroxyethoxy)benzene
    • 2,2'-(1,3-Phenylenebis(oxy))bisethanol
    • 2,2'-[1,3-Phenylenebis(oxy)]bisethanol
    • 2,2'-[Benzene-1,3-diylbis(oxy)]diethanol
    • O,O-BIS(.BETA.-HYDROXYETHYL)RESORCINOL
    • 2,2'-(1,3-PHENYLENEBIS(OXY)DIETHANOL
    • 2,2'-(BENZENE-1,3-DIYLBIS(OXY))DIETHANOL
    • 1,3-DIHYDROXYBENZENE DI(2-HYDROXYETHYL) ETHER
    • 1,3-DIHYDROXYBENZENE BIS(2-HYDROXYETHYL) ETHER
    • RefChem:413954
    • O,O-BIS(BETA-HYDROXYETHYL)RESORCINOL
    • Ethanol, 2,2'-(m-phenylenedioxy)di-(8CI)
    • 2,2'-(1,3-Phenylenebis(oxy))diethanol
    • 2-[3-(2-Hydroxyethoxy)phenoxy]ethanol
    • 2-[3-(2-hydroxyethoxy)phenoxy]ethan-1-ol
    • MFCD00016566
    • DTXSID7044502
    • Resorcinol bis(2-hydroxyethyl) ether 100 microg/mL in Acetonitrile
    • 74576-84-4
    • UNII-G4SGN7D66B
    • NCIOpen2_000309
    • SCHEMBL48418
    • CHEMBL3186062
    • DTXCID5024502
    • SCHEMBL17046324
    • IAXFZZHBFXRZMT-UHFFFAOYSA-
    • Ethanol,2'-(m-phenylenedioxy)di-
    • NSC65613
    • Resorcinol bis(2-hydroxyethyl)ether
    • Resorcinol-bis(2-hydroxyethyl)ether
    • Tox21_300783
    • AKOS024323131
    • FR74802
    • NCGC00248168-01
    • NCGC00254687-01
    • AS-63195
    • CAS-102-40-9
    • SY053901
    • 2-[3-(2-Hydroxyethoxy)phenoxy]ethanol #
    • Ethanol,2'-[1,3-phenylenebis(oxy)]bis-
    • B1625
    • CS-0206635
    • NS00020914
    • E85248
    • 2,2'-[1,3-Phenylenebis(oxy)]di(ethan-1-ol)
    • Q27278752
    • InChI=1/C10H14O4/c11-4-6-13-9-2-1-3-10(8-9)14-7-5-12/h1-3,8,11-12H,4-7H2
    • 102-40-9

  • Applications

    1,3-Bis(2-hydroxyethoxy)benzene (CAS 102-40-9) is a diol used as a building block in polymer formulations. In industry, it is commonly employed as a chain extender and crosslinkable polyol for polyurethane, polyester, and polyether resins, contributing to flexibility and chemical resistance. It also serves as a specialty monomer in UV-curable coatings and adhesives, where its two hydroxyl groups enable rapid curing and network formation. In electronics and optical coating applications, it can form part of transparent resin systems for encapsulation and protection of components. Additionally, it may act as an internal plasticizer in certain polymer formulations to improve processability and flexibility. Overall, it is primarily considered an intermediate for high-performance resins and specialty polymers, with use guided by formulation needs and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 116.82
    methanol 235.8
    isopropanol 62.34
    water 5.37
    ethyl acetate 50.99
    n-propanol 64.51
    acetone 160.54
    n-butanol 44.27
    acetonitrile 94.77
    DMF 403.7
    toluene 7.86
    isobutanol 38.37
    1,4-dioxane 154.33
    methyl acetate 74.77
    THF 177.78
    2-butanone 60.07
    n-pentanol 37.13
    sec-butanol 37.15
    n-hexane 1.96
    ethylene glycol 179.89
    NMP 226.66
    cyclohexane 6.09
    DMSO 1386.65
    n-butyl acetate 34.32
    n-octanol 19.78
    chloroform 103.53
    n-propyl acetate 37.5
    acetic acid 276.33
    dichloromethane 146.41
    cyclohexanone 91.67
    propylene glycol 120.95
    isopropyl acetate 24.03
    DMAc 354.86
    2-ethoxyethanol 159.75
    isopentanol 34.3
    n-heptane 3.47
    ethyl formate 63.16
    1,2-dichloroethane 110.25
    n-hexanol 31.44
    2-methoxyethanol 274.65
    isobutyl acetate 22.39
    tetrachloromethane 13.53
    n-pentyl acetate 18.12
    transcutol 235.28
    n-heptanol 15.42
    ethylbenzene 7.75
    MIBK 23.36
    2-propoxyethanol 88.09
    tert-butanol 104.36
    MTBE 38.27
    2-butoxyethanol 44.51
    propionic acid 100.83
    o-xylene 12.08
    formic acid 200.45
    diethyl ether 32.08
    m-xylene 8.27
    p-xylene 10.75
    chlorobenzene 23.64
    dimethyl carbonate 41.83
    n-octane 1.71
    formamide 273.84
    cyclopentanone 132.36
    2-pentanone 37.51
    anisole 34.21
    cyclopentyl methyl ether 43.95
    gamma-butyrolactone 182.0
    1-methoxy-2-propanol 125.46
    pyridine 73.84
    3-pentanone 34.36
    furfural 167.98
    n-dodecane 2.03
    diethylene glycol 149.76
    diisopropyl ether 8.06
    tert-amyl alcohol 55.94
    acetylacetone 75.17
    n-hexadecane 2.17
    acetophenone 43.79
    methyl propionate 54.98
    isopentyl acetate 29.68
    trichloroethylene 159.99
    n-nonanol 18.36
    cyclohexanol 50.69
    benzyl alcohol 41.6
    2-ethylhexanol 20.19
    isooctanol 13.59
    dipropyl ether 23.63
    1,2-dichlorobenzene 30.15
    ethyl lactate 46.09
    propylene carbonate 88.4
    n-methylformamide 175.37
    2-pentanol 21.15
    n-pentane 2.07
    1-propoxy-2-propanol 58.45
    1-methoxy-2-propyl acetate 44.36
    2-(2-methoxypropoxy) propanol 66.67
    mesitylene 7.39
    ε-caprolactone 81.31
    p-cymene 11.2
    epichlorohydrin 158.75
    1,1,1-trichloroethane 48.61
    2-aminoethanol 155.34
    morpholine-4-carbaldehyde 207.49
    sulfolane 321.01
    2,2,4-trimethylpentane 2.6
    2-methyltetrahydrofuran 72.8
    n-hexyl acetate 29.35
    isooctane 1.44
    2-(2-butoxyethoxy)ethanol 79.02
    sec-butyl acetate 20.15
    tert-butyl acetate 31.77
    decalin 3.72
    glycerin 221.9
    diglyme 161.21
    acrylic acid 120.05
    isopropyl myristate 14.47
    n-butyric acid 80.97
    acetyl acetate 48.14
    di(2-ethylhexyl) phthalate 22.46
    ethyl propionate 32.27
    nitromethane 351.64
    1,2-diethoxyethane 47.55
    benzonitrile 42.74
    trioctyl phosphate 16.3
    1-bromopropane 31.54
    gamma-valerolactone 154.65
    n-decanol 14.51
    triethyl phosphate 31.25
    4-methyl-2-pentanol 13.44
    propionitrile 51.08
    vinylene carbonate 85.93
    1,1,2-trichlorotrifluoroethane 216.93
    DMS 41.43
    cumene 8.16
    2-octanol 10.18
    2-hexanone 30.96
    octyl acetate 18.72
    limonene 17.29
    1,2-dimethoxyethane 204.76
    ethyl orthosilicate 27.21
    tributyl phosphate 22.25
    diacetone alcohol 56.52
    N,N-dimethylaniline 30.58
    acrylonitrile 85.63
    aniline 32.96
    1,3-propanediol 139.41
    bromobenzene 19.25
    dibromomethane 76.83
    1,1,2,2-tetrachloroethane 135.12
    2-methyl-cyclohexyl acetate 32.63
    tetrabutyl urea 32.81
    diisobutyl methanol 14.24
    2-phenylethanol 31.79
    styrene 10.61
    dioctyl adipate 32.35
    dimethyl sulfate 116.86
    ethyl butyrate 33.87
    methyl lactate 75.03
    butyl lactate 28.94
    diethyl carbonate 32.88
    propanediol butyl ether 56.54
    triethyl orthoformate 31.1
    p-tert-butyltoluene 10.95
    methyl 4-tert-butylbenzoate 42.69
    morpholine 174.43
    tert-butylamine 43.85
    n-dodecanol 12.27
    dimethoxymethane 126.34
    ethylene carbonate 70.57
    cyrene 76.98
    2-ethoxyethyl acetate 32.99
    2-ethylhexyl acetate 23.08
    1,2,4-trichlorobenzene 40.95
    4-methylpyridine 48.72
    dibutyl ether 19.95
    2,6-dimethyl-4-heptanol 14.24
    DEF 89.84
    dimethyl isosorbide 92.6
    tetrachloroethylene 87.6
    eugenol 46.35
    triacetin 51.56
    span 80 49.82
    1,4-butanediol 73.59
    1,1-dichloroethane 52.88
    2-methyl-1-pentanol 29.54
    methyl formate 140.49
    2-methyl-1-butanol 32.37
    n-decane 2.91
    butyronitrile 40.57
    3,7-dimethyl-1-octanol 19.7
    1-chlorooctane 10.86
    1-chlorotetradecane 5.56
    n-nonane 2.64
    undecane 2.32
    tert-butylcyclohexane 3.1
    cyclooctane 2.3
    cyclopentanol 61.64
    tetrahydropyran 72.84
    tert-amyl methyl ether 30.66
    2,5,8-trioxanonane 127.85
    1-hexene 6.96
    2-isopropoxyethanol 78.23
    2,2,2-trifluoroethanol 125.32
    methyl butyrate 51.12

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction