1,2,3,4-Tetrahydro-1-naphthalenol

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  • Identifiers

    CAS number
    529-33-9

    Molecular formula
    C10H12O

    SMILES
    C1CC(C2=CC=CC=C2C1)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Floral 65.69%
    Sweet 51.71%
    Animal 43.75%
    Rose 42.97%
    Phenolic 42.69%
    Balsamic 33.39%
    Aromatic 30.81%
    Anisic 30.68%
    Mint 29.77%
    Powdery 29.56%

     

    Flavor
    Sweet 56.98%
    Bitter 37.7%
    Phenolic 31.76%
    Floral 31.73%
    Powdery 31.37%
    Animal 30.32%
    Medicinal 29.66%
    Balsam 26.92%
    Spicy 25.9%
    Herbal 25.76%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.8

    pKa est.
    7.98 (neutral)

    Molecular weight
    148.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    259°C

    Flash point

    • 117.03 ˚C est.

  • Synonyms

    • 1,2,3,4-Tetrahydro-1-naphthalenol
    • RefChem:77271
    • 1,2,3,4-Tetrahydro-1-naphthol
    • 529-33-9
    • 1,2,3,4-Tetrahydronaphthalen-1-ol
    • Tetralin-1-ol
    • 1-Tetralol
    • alpha-Tetralol
    • 1-Hydroxytetralin
    • 1-Naphthalenol, 1,2,3,4-tetrahydro-
    • MFCD00001739
    • .alpha.-Tetralol
    • NSC 5172
    • 1-NAPHTHOL, 1,2,3,4-TETRAHYDRO-
    • Tetrahydro-1-naphthol
    • 1,2,3,4-tetrahydronaphthol
    • DTXSID7027174
    • 1,2,3,4-tetrahydro-1-napthol
    • NSC-5172
    • 1-Hydroxy-1,2,3,4-tetrahydronaphthalene
    • 87652943HP
    • Tetrahydro-1-naphthol (VAN)
    • 5929-35-1
    • 1,2,3,4-Tetrahydro-alpha-naphthol
    • EINECS 208-459-0
    • BRN 2046227
    • a-Tetralol
    • AI3-07039
    • 1,2,3,4-Tetrahydro-naphthalen-1-ol
    • ac-alpha-Tetralol
    • 1-hydroxytetraline
    • UNII-87652943HP
    • J6.683D
    • (+/-)-1,2,3,4-Tetrahydro-1-naphthol
    • SCHEMBL59025
    • SCHEMBL59026
    • WLN: L66&TJ GQ
    • 3-06-00-02457 (Beilstein Handbook Reference)
    • SCHEMBL303530
    • 1,3,4-Tetrahydro-1-naphthol
    • CHEMBL357784
    • DTXCID607174
    • orb3030560
    • SCHEMBL1403578
    • SCHEMBL1450966
    • SCHEMBL1451058
    • SCHEMBL4142319
    • SCHEMBL6634371
    • SCHEMBL8539846
    • (+/-)-1-TETRALOL
    • SCHEMBL14697151
    • SCHEMBL29449692
    • 1-Naphthol,2,3,4-tetrahydro-
    • NSC5172
    • HMS1786A14
    • (+/-)-.ALPHA.-TETRALOL
    • 1-Naphthalenol,2,3,4-tetrahydro-
    • Tox21_200096
    • 1,3,4-Tetrahydro-.alpha.-naphthol
    • SBB056331
    • AKOS000120875
    • AKOS016843173
    • CS-W004317
    • FT54815
    • SB44859
    • SB44892
    • 1,2,3,4-Tetrahydro-.alpha.-naphthol
    • NCGC00248522-01
    • NCGC00257650-01
    • 1,2,3,4-Tetrahydro-1-naphthol, 97%
    • CAS-529-33-9
    • DS-15486
    • SY009329
    • DB-017844
    • DB-018710
    • NS00013221
    • ST50824144
    • T1111
    • 1-NAPHTHALENOL,1,2,3,4-TETRAHYDRO-
    • EN300-17243
    • F069137
    • Q27269799
    • Z56899171
    • 1,2,3,4-Tetrahydro-1-naphthol, purum, >=97.0% (GC)
    • 529-33-9

  • Applications

    1,2,3,4-Tetrahydro-1-naphthalenol is primarily used as an organic building block and intermediate in chemical manufacturing. In fragrance and flavor applications, it serves as a precursor for more complex aroma compounds and can function as a fragrance intermediate or odorant precursor. In cosmetics and personal care, it is used as an intermediate in the synthesis of fragrance-related ingredients or as part of aroma-enhanced formulations. In the dye and pigment industry, it appears as a synthetic intermediate for dye and pigment precursors. In polymers and plastics, it can be used as a starting material for specialty monomers or cross-linking agents, or as an intermediate in resin formulations for coatings. It is a versatile intermediate in various industrial manufacturing processes, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 740.49
    methanol 840.1
    isopropanol 540.47
    water 1.72
    ethyl acetate 698.45
    n-propanol 569.35
    acetone 1072.75
    n-butanol 446.96
    acetonitrile 1104.87
    DMF 941.05
    toluene 290.34
    isobutanol 358.14
    1,4-dioxane 2756.02
    methyl acetate 722.11
    THF 1744.35
    2-butanone 692.22
    n-pentanol 282.67
    sec-butanol 275.9
    n-hexane 64.9
    ethylene glycol 95.14
    NMP 608.83
    cyclohexane 78.78
    DMSO 1547.19
    n-butyl acetate 521.59
    n-octanol 164.41
    chloroform 1542.96
    n-propyl acetate 493.02
    acetic acid 417.23
    dichloromethane 1502.93
    cyclohexanone 893.45
    propylene glycol 75.41
    isopropyl acetate 320.05
    DMAc 325.05
    2-ethoxyethanol 453.75
    isopentanol 305.57
    n-heptane 53.29
    ethyl formate 544.28
    1,2-dichloroethane 1129.15
    n-hexanol 359.83
    2-methoxyethanol 711.5
    isobutyl acetate 271.18
    tetrachloromethane 245.34
    n-pentyl acetate 235.42
    transcutol 1395.92
    n-heptanol 171.56
    ethylbenzene 125.76
    MIBK 295.82
    2-propoxyethanol 585.37
    tert-butanol 433.13
    MTBE 452.58
    2-butoxyethanol 308.37
    propionic acid 408.51
    o-xylene 131.04
    formic acid 133.83
    diethyl ether 888.54
    m-xylene 159.98
    p-xylene 149.8
    chlorobenzene 426.13
    dimethyl carbonate 205.32
    n-octane 28.09
    formamide 296.49
    cyclopentanone 1058.82
    2-pentanone 554.06
    anisole 303.6
    cyclopentyl methyl ether 604.46
    gamma-butyrolactone 1268.37
    1-methoxy-2-propanol 467.17
    pyridine 956.08
    3-pentanone 371.88
    furfural 710.28
    n-dodecane 23.1
    diethylene glycol 393.44
    diisopropyl ether 161.38
    tert-amyl alcohol 232.61
    acetylacetone 516.83
    n-hexadecane 26.48
    acetophenone 231.42
    methyl propionate 453.14
    isopentyl acetate 335.64
    trichloroethylene 1392.46
    n-nonanol 140.32
    cyclohexanol 303.48
    benzyl alcohol 199.19
    2-ethylhexanol 184.42
    isooctanol 143.29
    dipropyl ether 328.18
    1,2-dichlorobenzene 283.08
    ethyl lactate 139.69
    propylene carbonate 514.14
    n-methylformamide 695.74
    2-pentanol 240.3
    n-pentane 54.51
    1-propoxy-2-propanol 366.57
    1-methoxy-2-propyl acetate 331.44
    2-(2-methoxypropoxy) propanol 212.61
    mesitylene 110.27
    ε-caprolactone 731.71
    p-cymene 80.81
    epichlorohydrin 1465.89
    1,1,1-trichloroethane 735.14
    2-aminoethanol 191.89
    morpholine-4-carbaldehyde 921.31
    sulfolane 1087.23
    2,2,4-trimethylpentane 24.69
    2-methyltetrahydrofuran 982.46
    n-hexyl acetate 299.27
    isooctane 31.15
    2-(2-butoxyethoxy)ethanol 373.81
    sec-butyl acetate 229.77
    tert-butyl acetate 316.75
    decalin 39.37
    glycerin 138.39
    diglyme 771.84
    acrylic acid 292.69
    isopropyl myristate 124.84
    n-butyric acid 529.33
    acetyl acetate 287.35
    di(2-ethylhexyl) phthalate 86.79
    ethyl propionate 324.28
    nitromethane 1173.01
    1,2-diethoxyethane 578.76
    benzonitrile 345.81
    trioctyl phosphate 80.74
    1-bromopropane 581.59
    gamma-valerolactone 1282.6
    n-decanol 110.13
    triethyl phosphate 105.99
    4-methyl-2-pentanol 140.09
    propionitrile 695.03
    vinylene carbonate 496.53
    1,1,2-trichlorotrifluoroethane 445.09
    DMS 234.98
    cumene 84.41
    2-octanol 118.23
    2-hexanone 416.95
    octyl acetate 151.64
    limonene 121.29
    1,2-dimethoxyethane 926.32
    ethyl orthosilicate 104.6
    tributyl phosphate 99.57
    diacetone alcohol 302.49
    N,N-dimethylaniline 153.74
    acrylonitrile 772.97
    aniline 307.28
    1,3-propanediol 347.4
    bromobenzene 439.39
    dibromomethane 976.22
    1,1,2,2-tetrachloroethane 902.99
    2-methyl-cyclohexyl acetate 171.23
    tetrabutyl urea 123.78
    diisobutyl methanol 120.09
    2-phenylethanol 219.71
    styrene 172.88
    dioctyl adipate 142.84
    dimethyl sulfate 274.6
    ethyl butyrate 312.0
    methyl lactate 159.96
    butyl lactate 149.46
    diethyl carbonate 177.78
    propanediol butyl ether 224.78
    triethyl orthoformate 175.33
    p-tert-butyltoluene 79.8
    methyl 4-tert-butylbenzoate 191.56
    morpholine 1994.47
    tert-butylamine 260.26
    n-dodecanol 87.28
    dimethoxymethane 799.04
    ethylene carbonate 484.04
    cyrene 186.32
    2-ethoxyethyl acetate 317.06
    2-ethylhexyl acetate 259.28
    1,2,4-trichlorobenzene 317.58
    4-methylpyridine 758.57
    dibutyl ether 272.11
    2,6-dimethyl-4-heptanol 120.09
    DEF 491.67
    dimethyl isosorbide 367.17
    tetrachloroethylene 650.56
    eugenol 189.72
    triacetin 212.65
    span 80 186.77
    1,4-butanediol 129.37
    1,1-dichloroethane 1003.16
    2-methyl-1-pentanol 190.25
    methyl formate 579.73
    2-methyl-1-butanol 247.53
    n-decane 37.44
    butyronitrile 652.25
    3,7-dimethyl-1-octanol 136.19
    1-chlorooctane 138.44
    1-chlorotetradecane 55.76
    n-nonane 37.26
    undecane 28.91
    tert-butylcyclohexane 41.75
    cyclooctane 31.65
    cyclopentanol 367.17
    tetrahydropyran 1513.43
    tert-amyl methyl ether 228.63
    2,5,8-trioxanonane 418.94
    1-hexene 233.85
    2-isopropoxyethanol 309.6
    2,2,2-trifluoroethanol 146.79
    methyl butyrate 452.03

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction