12-Oxahexadecanolide

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  • Identifiers

    CAS number
    6707-60-4

    Molecular formula
    C15H28O3

    SMILES
    C1CCCCCOCCCCOC(=O)CCCC1

  • Odor profile

    Sweet 85.51%
    Musk 81.06%
    Fruity 66.56%
    Animal 61.36%
    Floral 49.23%
    Waxy 48.96%
    Woody 47.99%
    Amber 46.62%
    Oily 46.13%
    Powdery 46.12%

    Scent© AI

  • Properties

    XLogP3-AA
    4.2

    Molecular weight
    256.38 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    336°C

    Flash point est.
    161.58 ˚C

  • Synonyms

    • 1,6-Dioxacycloheptadecan-7-one
    • 12-Oxahexadecanolide
    • 6707-60-4
    • Cervolide
    • Hibiscolide
    • 12-Oxa-1,16-hexadecanolide
    • Musk 781
    • UNII-G6U2GR91JI
    • EINECS 229-755-6
    • G6U2GR91JI
    • NSC 34741
    • BRN 0158802
    • DTXSID4047705
    • NSC-34741
    • 16-Hydroxy-12 oxahexadecanoic acid, omega-lactone
    • 16-Hydroxy-12-oxahexadecanoic acid, omega-lactone
    • 1,6-DIOXACYCLOHEPTADECAN-17-ONE
    • Undecanoic acid, 11-(4-hydroxybutoxy)-, omicron-lactone
    • DTXCID2027703
    • 12-Oxahexadecan-16-olide
    • Undecanoic acid, 11-(4-hydroxybutoxy)-, .omicron.-lactone
    • NSC34741
    • 12-oxa-hexadecanolide
    • ST011693
    • Oprea1_119748
    • Oprea1_318261
    • SCHEMBL114946
    • CHEMBL3186263
    • 12-oxahexadecanolide, AldrichCPR
    • 1,6-Dioxa-7-cyclo-heptadecanone
    • Undecanoic acid, .omicron.-lactone
    • Tox21_302556
    • BBL009807
    • STL145847
    • AKOS000623162
    • NCGC00256800-01
    • VS-02192
    • CAS-6707-60-4
    • CS-0322673
    • NS00012619
    • G84789
    • A835626
    • 16-Hydroxy-12-oxahexadecanoic acid, .omega.-lactone
    • Q27278856
    • 229-755-6

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 739.4
    methanol 764.23
    isopropanol 703.4
    water 0.12
    ethyl acetate 1431.56
    n-propanol 671.85
    acetone 1416.99
    n-butanol 636.93
    acetonitrile 1141.34
    DMF 1072.7
    toluene 672.01
    isobutanol 540.21
    1,4-dioxane 1303.15
    methyl acetate 820.88
    THF 1905.11
    2-butanone 1045.28
    n-pentanol 441.63
    sec-butanol 595.26
    n-hexane 172.02
    ethylene glycol 73.4
    NMP 1075.48
    cyclohexane 410.73
    DMSO 2036.43
    n-butyl acetate 979.07
    n-octanol 252.82
    chloroform 4178.75
    n-propyl acetate 1040.82
    acetic acid 1062.6
    dichloromethane 3852.82
    cyclohexanone 1918.86
    propylene glycol 146.87
    isopropyl acetate 915.38
    DMAc 995.28
    2-ethoxyethanol 650.42
    isopentanol 636.93
    n-heptane 115.4
    ethyl formate 690.98
    1,2-dichloroethane 2231.41
    n-hexanol 407.47
    2-methoxyethanol 884.48
    isobutyl acetate 609.27
    tetrachloromethane 549.25
    n-pentyl acetate 788.59
    transcutol 2620.77
    n-heptanol 224.7
    ethylbenzene 354.05
    MIBK 701.32
    2-propoxyethanol 623.28
    tert-butanol 783.62
    MTBE 732.81
    2-butoxyethanol 521.32
    propionic acid 730.0
    o-xylene 395.14
    formic acid 222.32
    diethyl ether 1056.81
    m-xylene 403.81
    p-xylene 464.63
    chlorobenzene 1071.76
    dimethyl carbonate 271.53
    n-octane 44.95
    formamide 386.06
    cyclopentanone 1856.25
    2-pentanone 1100.32
    anisole 593.96
    cyclopentyl methyl ether 1051.42
    gamma-butyrolactone 1948.55
    1-methoxy-2-propanol 750.67
    pyridine 1859.31
    3-pentanone 776.75
    furfural 1644.05
    n-dodecane 30.14
    diethylene glycol 359.67
    diisopropyl ether 317.47
    tert-amyl alcohol 628.76
    acetylacetone 1160.51
    n-hexadecane 36.26
    acetophenone 660.65
    methyl propionate 779.63
    isopentyl acetate 756.92
    trichloroethylene 3674.92
    n-nonanol 225.67
    cyclohexanol 879.38
    benzyl alcohol 503.19
    2-ethylhexanol 321.32
    isooctanol 215.4
    dipropyl ether 609.84
    1,2-dichlorobenzene 980.15
    ethyl lactate 326.5
    propylene carbonate 1100.73
    n-methylformamide 636.15
    2-pentanol 520.32
    n-pentane 132.04
    1-propoxy-2-propanol 586.27
    1-methoxy-2-propyl acetate 671.88
    2-(2-methoxypropoxy) propanol 444.41
    mesitylene 266.36
    ε-caprolactone 1578.87
    p-cymene 219.99
    epichlorohydrin 1989.94
    1,1,1-trichloroethane 1832.07
    2-aminoethanol 234.37
    morpholine-4-carbaldehyde 1084.25
    sulfolane 2063.39
    2,2,4-trimethylpentane 63.76
    2-methyltetrahydrofuran 1461.72
    n-hexyl acetate 792.91
    isooctane 48.88
    2-(2-butoxyethoxy)ethanol 698.94
    sec-butyl acetate 646.31
    tert-butyl acetate 819.81
    decalin 136.56
    glycerin 224.15
    diglyme 1397.66
    acrylic acid 565.28
    isopropyl myristate 269.66
    n-butyric acid 1418.86
    acetyl acetate 866.82
    di(2-ethylhexyl) phthalate 228.23
    ethyl propionate 802.2
    nitromethane 1716.57
    1,2-diethoxyethane 997.79
    benzonitrile 895.79
    trioctyl phosphate 166.65
    1-bromopropane 1329.11
    gamma-valerolactone 1952.63
    n-decanol 152.25
    triethyl phosphate 296.62
    4-methyl-2-pentanol 310.8
    propionitrile 900.57
    vinylene carbonate 1017.51
    1,1,2-trichlorotrifluoroethane 1336.36
    DMS 517.15
    cumene 226.8
    2-octanol 187.3
    2-hexanone 804.8
    octyl acetate 326.75
    limonene 353.35
    1,2-dimethoxyethane 1247.68
    ethyl orthosilicate 280.35
    tributyl phosphate 238.85
    diacetone alcohol 671.11
    N,N-dimethylaniline 367.67
    acrylonitrile 1057.96
    aniline 739.21
    1,3-propanediol 453.31
    bromobenzene 1289.18
    dibromomethane 2635.16
    1,1,2,2-tetrachloroethane 2931.3
    2-methyl-cyclohexyl acetate 478.34
    tetrabutyl urea 295.99
    diisobutyl methanol 223.02
    2-phenylethanol 379.59
    styrene 518.38
    dioctyl adipate 420.45
    dimethyl sulfate 466.14
    ethyl butyrate 746.17
    methyl lactate 316.78
    butyl lactate 478.63
    diethyl carbonate 464.77
    propanediol butyl ether 459.13
    triethyl orthoformate 475.5
    p-tert-butyltoluene 193.91
    methyl 4-tert-butylbenzoate 502.55
    morpholine 1566.78
    tert-butylamine 513.85
    n-dodecanol 115.66
    dimethoxymethane 709.96
    ethylene carbonate 950.58
    cyrene 382.69
    2-ethoxyethyl acetate 823.26
    2-ethylhexyl acetate 600.97
    1,2,4-trichlorobenzene 1045.48
    4-methylpyridine 1515.75
    dibutyl ether 612.16
    2,6-dimethyl-4-heptanol 223.02
    DEF 1089.48
    dimethyl isosorbide 725.34
    tetrachloroethylene 2109.94
    eugenol 424.5
    triacetin 765.54
    span 80 463.25
    1,4-butanediol 182.25
    1,1-dichloroethane 2074.73
    2-methyl-1-pentanol 422.94
    methyl formate 434.85
    2-methyl-1-butanol 548.38
    n-decane 60.44
    butyronitrile 1016.26
    3,7-dimethyl-1-octanol 280.74
    1-chlorooctane 268.22
    1-chlorotetradecane 90.33
    n-nonane 62.06
    undecane 39.69
    tert-butylcyclohexane 101.89
    cyclooctane 113.51
    cyclopentanol 784.57
    tetrahydropyran 1784.61
    tert-amyl methyl ether 540.02
    2,5,8-trioxanonane 807.13
    1-hexene 507.22
    2-isopropoxyethanol 515.98
    2,2,2-trifluoroethanol 321.62
    methyl butyrate 1155.93

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction