12-Hydroxydodecanoic Acid

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  • Identifiers

    CAS number
    505-95-3

    Molecular formula
    C12H24O3

    SMILES
    C(CCCCCC(=O)O)CCCCCO

    Safety labels

  • Odor profile

    Fragrance
    Fatty 50.13%
    Waxy 47.9%
    Odorless 34.66%
    Oily 33.09%
    Citrus 31.34%
    Fresh 29.52%
    Sweet 28.41%
    Clean 24.99%
    Soapy 24.15%
    Milky 24.08%

     

    Flavor
    Waxy 66.62%
    Fatty 63.55%
    Oily 40.8%
    Green 40.58%
    Fat 38.64%
    Cheese 38.18%
    Soapy 37.63%
    Coconut 35.84%
    Creamy 33.6%
    Fruity 33.55%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.6

    pKa est.
    6.91 (neutral)

    Molecular weight
    216.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    341°C

    Melting point expt.

    • 85.00 to 88.00 °C. @ 760.00 mm Hg

    Flash point

    • 180.48 ˚C est.

  • Synonyms

    • 12-Hydroxydodecanoic acid
    • 505-95-3
    • 12-hydroxylauric acid
    • omega-hydroxylauric acid
    • SUH3LR2K9D
    • CHEBI:39567
    • DTXSID90198521
    • NSC-159293
    • NSC-664211
    • RefChem:437341
    • DTXCID50121012
    • 208-025-0
    • Dodecanoic acid,12-hydroxy-
    • Dodecanoic acid, 12-hydroxy-
    • Sabinic acid
    • MFCD00002739
    • 12-hydroxy-dodecanoic acid
    • 12-hydroxy lauric acid
    • omega-Hydroxydodecanoic acid
    • omega-hydroxydodecanoate
    • CHEMBL55068
    • NSC664211
    • 12-HYDROXYDODECANOICACID
    • 12H
    • 27925-01-5
    • EINECS 208-025-0
    • omega-OH lauric acid
    • NSC 159293
    • NSC 664211
    • omega hydroxy dodecanoate
    • omega-OH dodecanoic acid
    • omega-hydroxy lauric acid
    • UNII-SUH3LR2K9D
    • 12-hydroxy dodecanoic acid
    • omega hydroxy dodecanoic acid
    • omega-hydroxy dodecanoic acid
    • SCHEMBL154530
    • GTPL6922
    • orb1302486
    • SCHEMBL1006815
    • HO-(CH2)11-CO2H
    • 12-Hydroxydodecanoic acid, 97%
    • BDBM50511009
    • LMFA01050039
    • NSC159293
    • s3089
    • SBB061512
    • AKOS015893931
    • DB03704
    • EBC-616170
    • BP-12860
    • DS-15787
    • SY022052
    • DB-030561
    • HY-128743
    • CS-0102534
    • NS00014775
    • ST51047515
    • C08317
    • O10368
    • Q27070761
    • 505-95-3

  • Applications

    12-Hydroxydodecanoic Acid (CAS 505-95-3) is an omega-hydroxy fatty acid widely used as a building block for polymers and specialty esters; as a diol/functional unit it enables polyesters and polyurethanes for coatings and adhesives; it also serves as a surfactant or emulsifier in cosmetics and personal care; in industrial manufacturing it is used as a processing aid and lubricant to improve handling and processing; it can be transformed into specialty esters or polymer modifiers to tune material properties; and its use in cleaning formulations may be explored, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 308.23
    methanol 453.26
    isopropanol 230.18
    water 0.1
    ethyl acetate 68.54
    n-propanol 202.3
    acetone 125.35
    n-butanol 187.86
    acetonitrile 29.42
    DMF 324.68
    toluene 21.15
    isobutanol 161.09
    1,4-dioxane 159.73
    methyl acetate 45.38
    THF 584.04
    2-butanone 87.45
    n-pentanol 161.87
    sec-butanol 143.97
    n-hexane 24.74
    ethylene glycol 46.71
    NMP 303.99
    cyclohexane 22.84
    DMSO 965.33
    n-butyl acetate 134.57
    n-octanol 65.76
    chloroform 98.79
    n-propyl acetate 124.63
    acetic acid 129.64
    dichloromethane 87.99
    cyclohexanone 262.86
    propylene glycol 115.77
    isopropyl acetate 87.96
    DMAc 217.79
    2-ethoxyethanol 266.37
    isopentanol 193.12
    n-heptane 12.87
    ethyl formate 58.98
    1,2-dichloroethane 105.13
    n-hexanol 147.19
    2-methoxyethanol 404.02
    isobutyl acetate 95.36
    tetrachloromethane 24.17
    n-pentyl acetate 104.2
    transcutol 712.08
    n-heptanol 75.7
    ethylbenzene 25.81
    MIBK 126.29
    2-propoxyethanol 263.56
    tert-butanol 318.04
    MTBE 120.97
    2-butoxyethanol 184.55
    propionic acid 112.66
    o-xylene 29.77
    formic acid 64.63
    diethyl ether 85.99
    m-xylene 31.39
    p-xylene 33.09
    chlorobenzene 35.46
    dimethyl carbonate 23.62
    n-octane 5.57
    formamide 93.1
    cyclopentanone 312.29
    2-pentanone 130.18
    anisole 62.28
    cyclopentyl methyl ether 207.77
    gamma-butyrolactone 297.0
    1-methoxy-2-propanol 360.78
    pyridine 94.37
    3-pentanone 62.86
    furfural 213.28
    n-dodecane 3.86
    diethylene glycol 182.26
    diisopropyl ether 41.04
    tert-amyl alcohol 193.35
    acetylacetone 147.91
    n-hexadecane 4.41
    acetophenone 83.16
    methyl propionate 61.01
    isopentyl acetate 136.77
    trichloroethylene 150.57
    n-nonanol 60.33
    cyclohexanol 179.37
    benzyl alcohol 74.74
    2-ethylhexanol 90.19
    isooctanol 70.64
    dipropyl ether 100.07
    1,2-dichlorobenzene 47.3
    ethyl lactate 72.71
    propylene carbonate 149.94
    n-methylformamide 129.36
    2-pentanol 126.51
    n-pentane 11.69
    1-propoxy-2-propanol 219.54
    1-methoxy-2-propyl acetate 136.4
    2-(2-methoxypropoxy) propanol 140.55
    mesitylene 28.24
    ε-caprolactone 214.0
    p-cymene 25.58
    epichlorohydrin 262.92
    1,1,1-trichloroethane 68.21
    2-aminoethanol 164.81
    morpholine-4-carbaldehyde 268.71
    sulfolane 573.34
    2,2,4-trimethylpentane 9.68
    2-methyltetrahydrofuran 267.18
    n-hexyl acetate 123.95
    isooctane 8.64
    2-(2-butoxyethoxy)ethanol 227.77
    sec-butyl acetate 86.97
    tert-butyl acetate 140.96
    decalin 15.06
    glycerin 167.13
    diglyme 394.3
    acrylic acid 75.88
    isopropyl myristate 45.8
    n-butyric acid 221.83
    acetyl acetate 49.18
    di(2-ethylhexyl) phthalate 49.78
    ethyl propionate 82.91
    nitromethane 144.6
    1,2-diethoxyethane 157.11
    benzonitrile 60.54
    trioctyl phosphate 41.57
    1-bromopropane 63.05
    gamma-valerolactone 386.75
    n-decanol 41.29
    triethyl phosphate 53.46
    4-methyl-2-pentanol 89.39
    propionitrile 45.44
    vinylene carbonate 94.41
    1,1,2-trichlorotrifluoroethane 244.49
    DMS 62.75
    cumene 26.9
    2-octanol 50.58
    2-hexanone 135.45
    octyl acetate 56.96
    limonene 43.37
    1,2-dimethoxyethane 326.58
    ethyl orthosilicate 57.06
    tributyl phosphate 51.99
    diacetone alcohol 222.16
    N,N-dimethylaniline 58.68
    acrylonitrile 50.23
    aniline 49.72
    1,3-propanediol 241.75
    bromobenzene 32.96
    dibromomethane 69.84
    1,1,2,2-tetrachloroethane 177.93
    2-methyl-cyclohexyl acetate 100.45
    tetrabutyl urea 72.31
    diisobutyl methanol 55.96
    2-phenylethanol 77.65
    styrene 26.58
    dioctyl adipate 80.55
    dimethyl sulfate 73.85
    ethyl butyrate 98.75
    methyl lactate 75.89
    butyl lactate 110.07
    diethyl carbonate 53.03
    propanediol butyl ether 179.54
    triethyl orthoformate 82.7
    p-tert-butyltoluene 26.81
    methyl 4-tert-butylbenzoate 101.06
    morpholine 320.41
    tert-butylamine 169.28
    n-dodecanol 29.57
    dimethoxymethane 168.49
    ethylene carbonate 87.36
    cyrene 138.54
    2-ethoxyethyl acetate 119.29
    2-ethylhexyl acetate 98.29
    1,2,4-trichlorobenzene 58.4
    4-methylpyridine 85.06
    dibutyl ether 83.4
    2,6-dimethyl-4-heptanol 55.96
    DEF 157.08
    dimethyl isosorbide 228.21
    tetrachloroethylene 126.37
    eugenol 104.85
    triacetin 129.27
    span 80 137.52
    1,4-butanediol 93.49
    1,1-dichloroethane 65.66
    2-methyl-1-pentanol 134.09
    methyl formate 57.63
    2-methyl-1-butanol 147.81
    n-decane 7.79
    butyronitrile 77.68
    3,7-dimethyl-1-octanol 71.63
    1-chlorooctane 35.66
    1-chlorotetradecane 12.23
    n-nonane 7.47
    undecane 5.14
    tert-butylcyclohexane 14.54
    cyclooctane 8.18
    cyclopentanol 225.21
    tetrahydropyran 238.72
    tert-amyl methyl ether 99.31
    2,5,8-trioxanonane 255.33
    1-hexene 70.4
    2-isopropoxyethanol 196.84
    2,2,2-trifluoroethanol 43.78
    methyl butyrate 134.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction