1,2-Hexadecanediol

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  • Identifiers

    CAS number
    6920-24-7

    Molecular formula
    C16H34O2

    SMILES
    CCCCCCCCCCCCCCC(CO)O

    Safety labels

  • Odor profile

    Fragrance
    Waxy 68.88%
    Fatty 55.86%
    Oily 48.42%
    Odorless 34.13%
    Clean 24.82%
    Citrus 24.43%
    Fruity 23.72%
    Sweet 23.59%
    Soapy 23.44%
    Coconut 22.74%

     

    Flavor
    Waxy 54.51%
    Fatty 43.94%
    Mild 39.25%
    Fat 33.21%
    Oily 31.2%
    Floral 29.61%
    Flower 29.16%
    Soapy 28.94%
    Bland 27.67%
    Coconut 26.08%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.1

    pKa est.
    7.24 (neutral)

    Molecular weight
    258.44 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    347°C

    Flash point

    • 172.23 ˚C est.

  • Synonyms

    • 1,2-Hexadecanediol
    • 6920-24-7
    • Cetyl glycol
    • 1H07JK4G0C
    • NSC-71525
    • CHEBI:75586
    • DTXSID60884343
    • RefChem:72092
    • DTXCID801023790
    • 230-030-1
    • Hexadecane-1,2-diol
    • 1,2-Dihydroxyhexadecane
    • MFCD00004727
    • UNII-1H07JK4G0C
    • NSC71525
    • EINECS 230-030-1
    • 1,2-palmityl diol
    • NSC 71525
    • 1,2-hexadecyl diol
    • hexadecan-1,2-diol
    • AI3-14193
    • SCHEMBL28807
    • 2-HYDROXYCETYL ALCOHOL
    • (+/-)-CETYL GLYCOL
    • orb1705671
    • 1,2-HEXADECYLENE GLYCOL
    • SCHEMBL10865968
    • CETYL GLYCOL, (+/-)-
    • AKOS015902888
    • FH30638
    • AS-57146
    • PD212498
    • SY051626
    • 1,2-Hexadecanediol, technical grade, 90%
    • H0993
    • NS00013443
    • EN300-73462
    • D90985
    • F815042
    • Q27105052
    • 6920-24-7

  • Applications

    1,2-Hexadecanediol (CAS 6920-24-7) is commonly used in cosmetics and personal care as an emollient and conditioning agent, and as a humectant to help retain moisture in formulations. It may serve as a solvent or carrier for fragrances and active ingredients. In polymer and materials chemistry, it acts as a diol building block (chain extender or crosslinker) for polyurethane and polyester resins, contributing to coatings, adhesives, and plastics. It can function as a plasticizer in specialty polymer systems and may be used as a processing aid or reactive diluent in coatings and inks. Additionally, it is employed as an intermediate in chemical synthesis.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 176.48
    methanol 127.34
    isopropanol 264.42
    water 0.01
    ethyl acetate 418.15
    n-propanol 227.01
    acetone 289.95
    n-butanol 291.42
    acetonitrile 88.73
    DMF 317.31
    toluene 101.77
    isobutanol 234.66
    1,4-dioxane 448.73
    methyl acetate 204.09
    THF 1436.79
    2-butanone 347.83
    n-pentanol 201.82
    sec-butanol 271.03
    n-hexane 112.46
    ethylene glycol 8.82
    NMP 504.06
    cyclohexane 342.14
    DMSO 717.31
    n-butyl acetate 716.73
    n-octanol 182.97
    chloroform 576.87
    n-propyl acetate 577.39
    acetic acid 121.34
    dichloromethane 558.86
    cyclohexanone 957.43
    propylene glycol 36.47
    isopropyl acetate 442.41
    DMAc 352.82
    2-ethoxyethanol 312.74
    isopentanol 358.92
    n-heptane 183.95
    ethyl formate 178.02
    1,2-dichloroethane 507.38
    n-hexanol 261.2
    2-methoxyethanol 372.4
    isobutyl acetate 387.61
    tetrachloromethane 197.97
    n-pentyl acetate 606.75
    transcutol 1274.92
    n-heptanol 214.05
    ethylbenzene 103.53
    MIBK 438.93
    2-propoxyethanol 396.08
    tert-butanol 497.18
    MTBE 525.98
    2-butoxyethanol 420.45
    propionic acid 148.19
    o-xylene 108.85
    formic acid 15.91
    diethyl ether 430.05
    m-xylene 103.67
    p-xylene 144.42
    chlorobenzene 177.74
    dimethyl carbonate 67.34
    n-octane 57.04
    formamide 36.78
    cyclopentanone 937.13
    2-pentanone 482.14
    anisole 199.92
    cyclopentyl methyl ether 698.8
    gamma-butyrolactone 787.28
    1-methoxy-2-propanol 419.97
    pyridine 320.01
    3-pentanone 311.64
    furfural 457.93
    n-dodecane 22.43
    diethylene glycol 136.76
    diisopropyl ether 231.97
    tert-amyl alcohol 402.95
    acetylacetone 449.78
    n-hexadecane 27.56
    acetophenone 260.15
    methyl propionate 255.26
    isopentyl acetate 634.38
    trichloroethylene 698.4
    n-nonanol 178.09
    cyclohexanol 478.6
    benzyl alcohol 137.25
    2-ethylhexanol 292.12
    isooctanol 234.9
    dipropyl ether 752.94
    1,2-dichlorobenzene 231.41
    ethyl lactate 173.78
    propylene carbonate 457.07
    n-methylformamide 108.97
    2-pentanol 283.62
    n-pentane 78.21
    1-propoxy-2-propanol 536.05
    1-methoxy-2-propyl acetate 457.34
    2-(2-methoxypropoxy) propanol 255.97
    mesitylene 99.99
    ε-caprolactone 754.68
    p-cymene 138.4
    epichlorohydrin 752.0
    1,1,1-trichloroethane 555.37
    2-aminoethanol 47.02
    morpholine-4-carbaldehyde 481.72
    sulfolane 1240.59
    2,2,4-trimethylpentane 59.39
    2-methyltetrahydrofuran 889.93
    n-hexyl acetate 506.41
    isooctane 44.84
    2-(2-butoxyethoxy)ethanol 412.82
    sec-butyl acetate 433.75
    tert-butyl acetate 606.71
    decalin 93.43
    glycerin 59.43
    diglyme 914.19
    acrylic acid 76.74
    isopropyl myristate 192.52
    n-butyric acid 476.26
    acetyl acetate 222.06
    di(2-ethylhexyl) phthalate 113.8
    ethyl propionate 416.53
    nitromethane 251.52
    1,2-diethoxyethane 699.32
    benzonitrile 181.12
    trioctyl phosphate 117.23
    1-bromopropane 425.56
    gamma-valerolactone 990.64
    n-decanol 114.26
    triethyl phosphate 238.14
    4-methyl-2-pentanol 212.35
    propionitrile 145.88
    vinylene carbonate 273.63
    1,1,2-trichlorotrifluoroethane 498.44
    DMS 194.51
    cumene 95.3
    2-octanol 186.94
    2-hexanone 476.43
    octyl acetate 211.21
    limonene 273.47
    1,2-dimethoxyethane 731.26
    ethyl orthosilicate 262.52
    tributyl phosphate 157.37
    diacetone alcohol 534.0
    N,N-dimethylaniline 160.78
    acrylonitrile 115.3
    aniline 126.37
    1,3-propanediol 148.78
    bromobenzene 203.99
    dibromomethane 433.42
    1,1,2,2-tetrachloroethane 790.66
    2-methyl-cyclohexyl acetate 417.72
    tetrabutyl urea 212.5
    diisobutyl methanol 245.93
    2-phenylethanol 162.68
    styrene 112.58
    dioctyl adipate 268.02
    dimethyl sulfate 162.79
    ethyl butyrate 650.47
    methyl lactate 116.02
    butyl lactate 357.46
    diethyl carbonate 293.51
    propanediol butyl ether 273.97
    triethyl orthoformate 482.11
    p-tert-butyltoluene 136.12
    methyl 4-tert-butylbenzoate 301.4
    morpholine 712.81
    tert-butylamine 361.43
    n-dodecanol 81.58
    dimethoxymethane 293.73
    ethylene carbonate 304.54
    cyrene 248.55
    2-ethoxyethyl acetate 500.49
    2-ethylhexyl acetate 534.08
    1,2,4-trichlorobenzene 251.61
    4-methylpyridine 297.74
    dibutyl ether 528.41
    2,6-dimethyl-4-heptanol 245.93
    DEF 486.8
    dimethyl isosorbide 536.15
    tetrachloroethylene 532.79
    eugenol 222.23
    triacetin 394.71
    span 80 268.95
    1,4-butanediol 51.84
    1,1-dichloroethane 422.35
    2-methyl-1-pentanol 224.37
    methyl formate 74.51
    2-methyl-1-butanol 285.19
    n-decane 58.89
    butyronitrile 250.86
    3,7-dimethyl-1-octanol 221.16
    1-chlorooctane 213.08
    1-chlorotetradecane 61.26
    n-nonane 64.41
    undecane 33.35
    tert-butylcyclohexane 78.31
    cyclooctane 91.25
    cyclopentanol 445.48
    tetrahydropyran 992.82
    tert-amyl methyl ether 393.04
    2,5,8-trioxanonane 487.05
    1-hexene 229.66
    2-isopropoxyethanol 297.69
    2,2,2-trifluoroethanol 52.23
    methyl butyrate 615.47

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction