1,2-Dichloro-1,1,2,3,3-pentafluoropropane

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  • Identifiers

    CAS number
    422-44-6

    Molecular formula
    C3HCl2F5

    SMILES
    C(C(C(F)(F)Cl)(F)Cl)(F)F

  • Odor profile

    Fragrance
    Odorless 56.37%
    Fishy 26.77%
    Woody 23.71%
    Sweet 22.42%
    Cooling 21.35%
    Balsamic 17.88%
    Animal 16.81%
    Mint 15.57%
    Savory 15.53%
    Dry 15.33%

     

    Flavor
    Odorless 32.28%
    Bland 21.52%
    Sulfurous 21.14%
    Mild 18.12%
    Sweet-like 17.82%
    Bloody 17.71%
    Glue 17.58%
    Bitter 17.52%
    Bouillon 17.37%
    Skunky 17.06%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.4

    pKa est.
    4.4 (weak acid)

    Molecular weight
    202.93 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    57°C

    Flash point

    • 1.38 ˚C est.

  • Synonyms

    • 1,2-DICHLORO-1,1,2,3,3-PENTAFLUOROPROPANE
    • 422-44-6
    • HCFC-225bb
    • UNII-PV9W4A71T4
    • PV9W4A71T4
    • DTXSID6042026
    • R-225BA
    • Propane, 1,2-dichloro-1,1,2,3,3-pentafluoro-
    • 1,2-DICHLORO-1,1,2,3,3-PENTAFLUORO-PROPANE
    • SCHEMBL94227
    • DTXCID4022026
    • GDSQRBLILFKERU-UHFFFAOYSA-N
    • NS00121570
    • Q27286774

  • Applications

    1,2-Dichloro-1,1,2,3,3-pentafluoropropane is used chiefly as a specialty intermediate and solvent in fluorinated chemical manufacturing; it can serve as a precursor for fluorinated polymers and related materials. It is evaluated as a cleaning and degreasing solvent for electronics and precision components due to its chemical stability and solvency properties. It may be employed as a reactive intermediate in coatings and inks formulations to impart fluorinated surface characteristics such as chemical resistance and low surface energy. In some processes it can be explored as a building block for performance fluids or lubricants based on fluorinated chemistries. Usage is typically subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 470.11
    methanol 876.1
    isopropanol 323.25
    water 107.42
    ethyl acetate 196.99
    n-propanol 305.97
    acetone 725.32
    n-butanol 235.48
    acetonitrile 464.73
    DMF 1619.1
    toluene 70.01
    isobutanol 213.36
    1,4-dioxane 315.56
    methyl acetate 251.64
    THF 630.76
    2-butanone 425.98
    n-pentanol 209.99
    sec-butanol 260.76
    n-hexane 30.25
    ethylene glycol 253.54
    NMP 1132.27
    cyclohexane 51.67
    DMSO 2315.34
    n-butyl acetate 98.68
    n-octanol 88.15
    chloroform 126.2
    n-propyl acetate 162.91
    acetic acid 275.42
    dichloromethane 197.31
    cyclohexanone 320.06
    propylene glycol 171.73
    isopropyl acetate 146.13
    DMAc 1425.35
    2-ethoxyethanol 556.52
    isopentanol 202.99
    n-heptane 41.02
    ethyl formate 181.97
    1,2-dichloroethane 200.54
    n-hexanol 115.82
    2-methoxyethanol 756.38
    isobutyl acetate 73.93
    tetrachloromethane 30.39
    n-pentyl acetate 75.02
    transcutol 578.56
    n-heptanol 71.92
    ethylbenzene 52.2
    MIBK 211.65
    2-propoxyethanol 285.18
    tert-butanol 345.64
    MTBE 239.0
    2-butoxyethanol 154.98
    propionic acid 145.39
    o-xylene 87.27
    formic acid 337.99
    diethyl ether 304.59
    m-xylene 65.69
    p-xylene 60.15
    chlorobenzene 34.08
    dimethyl carbonate 164.52
    n-octane 17.27
    formamide 748.62
    cyclopentanone 429.87
    2-pentanone 357.62
    anisole 155.71
    cyclopentyl methyl ether 291.33
    gamma-butyrolactone 366.58
    1-methoxy-2-propanol 531.07
    pyridine 242.35
    3-pentanone 289.49
    furfural 327.85
    n-dodecane 11.67
    diethylene glycol 297.48
    diisopropyl ether 95.86
    tert-amyl alcohol 279.06
    acetylacetone 328.85
    n-hexadecane 12.5
    acetophenone 197.65
    methyl propionate 243.64
    isopentyl acetate 72.13
    trichloroethylene 188.94
    n-nonanol 81.21
    cyclohexanol 185.55
    benzyl alcohol 146.32
    2-ethylhexanol 72.09
    isooctanol 56.91
    dipropyl ether 154.49
    1,2-dichlorobenzene 33.44
    ethyl lactate 142.23
    propylene carbonate 138.08
    n-methylformamide 708.35
    2-pentanol 195.03
    n-pentane 59.14
    1-propoxy-2-propanol 205.31
    1-methoxy-2-propyl acetate 148.81
    2-(2-methoxypropoxy) propanol 204.89
    mesitylene 52.43
    ε-caprolactone 218.06
    p-cymene 49.51
    epichlorohydrin 376.18
    1,1,1-trichloroethane 88.11
    2-aminoethanol 327.2
    morpholine-4-carbaldehyde 797.9
    sulfolane 641.03
    2,2,4-trimethylpentane 23.82
    2-methyltetrahydrofuran 360.37
    n-hexyl acetate 93.24
    isooctane 16.38
    2-(2-butoxyethoxy)ethanol 231.11
    sec-butyl acetate 101.67
    tert-butyl acetate 148.06
    decalin 18.94
    glycerin 252.13
    diglyme 444.1
    acrylic acid 156.96
    isopropyl myristate 52.1
    n-butyric acid 143.92
    acetyl acetate 106.71
    di(2-ethylhexyl) phthalate 45.11
    ethyl propionate 157.36
    nitromethane 717.37
    1,2-diethoxyethane 191.96
    benzonitrile 107.28
    trioctyl phosphate 39.67
    1-bromopropane 137.79
    gamma-valerolactone 494.98
    n-decanol 62.94
    triethyl phosphate 65.14
    4-methyl-2-pentanol 118.33
    propionitrile 250.9
    vinylene carbonate 113.01
    1,1,2-trichlorotrifluoroethane 279.91
    DMS 91.39
    cumene 44.42
    2-octanol 57.59
    2-hexanone 235.11
    octyl acetate 64.77
    limonene 80.85
    1,2-dimethoxyethane 711.42
    ethyl orthosilicate 61.99
    tributyl phosphate 45.65
    diacetone alcohol 270.38
    N,N-dimethylaniline 202.1
    acrylonitrile 294.53
    aniline 123.53
    1,3-propanediol 305.46
    bromobenzene 27.49
    dibromomethane 142.56
    1,1,2,2-tetrachloroethane 172.51
    2-methyl-cyclohexyl acetate 81.24
    tetrabutyl urea 115.69
    diisobutyl methanol 60.69
    2-phenylethanol 92.89
    styrene 57.33
    dioctyl adipate 79.59
    dimethyl sulfate 289.38
    ethyl butyrate 121.21
    methyl lactate 207.27
    butyl lactate 83.58
    diethyl carbonate 71.26
    propanediol butyl ether 153.07
    triethyl orthoformate 84.77
    p-tert-butyltoluene 45.05
    methyl 4-tert-butylbenzoate 135.26
    morpholine 501.89
    tert-butylamine 233.9
    n-dodecanol 48.99
    dimethoxymethane 723.92
    ethylene carbonate 99.2
    cyrene 270.49
    2-ethoxyethyl acetate 103.41
    2-ethylhexyl acetate 60.19
    1,2,4-trichlorobenzene 45.34
    4-methylpyridine 230.52
    dibutyl ether 92.76
    2,6-dimethyl-4-heptanol 60.69
    DEF 546.08
    dimethyl isosorbide 306.21
    tetrachloroethylene 113.79
    eugenol 140.65
    triacetin 122.42
    span 80 119.68
    1,4-butanediol 190.04
    1,1-dichloroethane 130.27
    2-methyl-1-pentanol 153.08
    methyl formate 429.19
    2-methyl-1-butanol 195.78
    n-decane 19.23
    butyronitrile 211.73
    3,7-dimethyl-1-octanol 74.64
    1-chlorooctane 44.16
    1-chlorotetradecane 21.02
    n-nonane 19.73
    undecane 14.47
    tert-butylcyclohexane 16.0
    cyclooctane 25.54
    cyclopentanol 226.15
    tetrahydropyran 261.49
    tert-amyl methyl ether 223.43
    2,5,8-trioxanonane 353.05
    1-hexene 74.23
    2-isopropoxyethanol 330.3
    2,2,2-trifluoroethanol 175.23
    methyl butyrate 218.96

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction