1,2-Dichloro-1,1-difluoroethane

Overview IFRA Request a quote

  • Identifiers

    CAS number
    1649-08-7

    Molecular formula
    C2H2Cl2F2

    SMILES
    C(C(F)(F)Cl)Cl

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 45.7%
    Fishy 31.31%
    Sweet 29.08%
    Woody 23.5%
    Floral 21.92%
    Animal 20.58%
    Balsamic 20.14%
    Fresh 18.93%
    Cooling 18.85%
    Clean 18.36%

     

    Flavor
    Odorless 30.86%
    Sulfurous 28.42%
    Sulfury 24.18%
    Meaty 24.06%
    Mild 19.79%
    Bloody 18.92%
    Glue 18.8%
    Bouillon 18.37%
    Skunky 18.34%
    Fishy 18.03%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    5.89 (weak acid)

    Molecular weight
    134.94 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -101.2 °C

    Boiling point

    • 46.8 °C @ 760 mm Hg

    Flash point

    • -11.03 ˚C est.

    Solubility expt.

    • In water, 850 mg/l @ 24 °C

  • Synonyms

    • 1,2-DICHLORO-1,1-DIFLUOROETHANE
    • 1649-08-7
    • HCFC-132b
    • Ethane, 1,2-dichloro-1,1-difluoro-
    • DICHLORODIFLUOROETHANE
    • HSDB 6758
    • Ethane, dichlorodifluoro-
    • 1,1-Difluoro-1,2-dichloroethane
    • 1,2-dichloro-1,1-difluoro-ethane
    • EINECS 216-714-2
    • K90K8VM1NQ
    • BRN 1733206
    • 1,2-dichloro-2,2-difluoroethane
    • DTXSID5031393
    • 25915-78-0
    • 1,2-DICHLORO-1,1-DIFLUOROMETHANE
    • 1,2-DICHLORO-1,1-DIFLUOROETHANE [HSDB]
    • CF2ClCH2Cl
    • UNII-K90K8VM1NQ
    • HCFC132b
    • 1,2-DCDFE
    • SCHEMBL201982
    • DTXCID3011393
    • Ethane, 1,2dichloro1,1difluoro
    • DTXSID701019237
    • MFCD00042125
    • AKOS006230231
    • DB-043604
    • NS00048189
    • A810601
    • Q27282103
    • 216-714-2

  • Applications

    1,2-Dichloro-1,1-difluoroethane is used as a specialty chemical in industrial processing. It may serve as a solvent for niche applications such as electronics cleaning and precision surface preparation; as an intermediate in the synthesis of halogenated organic compounds; as a processing solvent or diluent in coatings, inks, and adhesives; and as a processing aid or reactive diluent in polymer and plastics manufacturing. In some cases, it may be evaluated for use as a refrigerant, a blowing agent for polymer foams, or other niche applications subject to regulatory controls.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 747.48
    methanol 1270.13
    isopropanol 513.81
    water 314.51
    ethyl acetate 453.28
    n-propanol 446.77
    acetone 1678.47
    n-butanol 340.01
    acetonitrile 1171.57
    DMF 3217.47
    toluene 251.82
    isobutanol 334.5
    1,4-dioxane 965.57
    methyl acetate 617.65
    THF 1070.23
    2-butanone 758.19
    n-pentanol 290.57
    sec-butanol 373.88
    n-hexane 130.34
    ethylene glycol 406.12
    NMP 1801.36
    cyclohexane 123.89
    DMSO 2887.61
    n-butyl acetate 208.2
    n-octanol 197.37
    chloroform 438.37
    n-propyl acetate 382.92
    acetic acid 685.21
    dichloromethane 680.33
    cyclohexanone 632.93
    propylene glycol 246.46
    isopropyl acetate 276.37
    DMAc 2165.04
    2-ethoxyethanol 810.41
    isopentanol 289.38
    n-heptane 83.04
    ethyl formate 496.22
    1,2-dichloroethane 622.42
    n-hexanol 180.13
    2-methoxyethanol 1243.86
    isobutyl acetate 192.89
    tetrachloromethane 111.85
    n-pentyl acetate 174.62
    transcutol 1182.03
    n-heptanol 112.77
    ethylbenzene 197.42
    MIBK 344.32
    2-propoxyethanol 489.48
    tert-butanol 552.55
    MTBE 461.52
    2-butoxyethanol 265.42
    propionic acid 337.94
    o-xylene 273.39
    formic acid 677.03
    diethyl ether 612.03
    m-xylene 216.09
    p-xylene 231.42
    chlorobenzene 180.0
    dimethyl carbonate 411.64
    n-octane 42.62
    formamide 1265.27
    cyclopentanone 812.05
    2-pentanone 574.73
    anisole 527.51
    cyclopentyl methyl ether 510.4
    gamma-butyrolactone 813.97
    1-methoxy-2-propanol 798.3
    pyridine 661.41
    3-pentanone 537.45
    furfural 956.87
    n-dodecane 38.43
    diethylene glycol 537.88
    diisopropyl ether 198.37
    tert-amyl alcohol 412.87
    acetylacetone 743.47
    n-hexadecane 40.24
    acetophenone 498.98
    methyl propionate 489.24
    isopentyl acetate 160.01
    trichloroethylene 638.31
    n-nonanol 177.25
    cyclohexanol 313.51
    benzyl alcohol 351.28
    2-ethylhexanol 135.69
    isooctanol 97.92
    dipropyl ether 297.4
    1,2-dichlorobenzene 183.37
    ethyl lactate 246.01
    propylene carbonate 361.11
    n-methylformamide 1349.61
    2-pentanol 266.45
    n-pentane 147.97
    1-propoxy-2-propanol 321.4
    1-methoxy-2-propyl acetate 267.1
    2-(2-methoxypropoxy) propanol 406.16
    mesitylene 165.32
    ε-caprolactone 479.95
    p-cymene 113.66
    epichlorohydrin 859.9
    1,1,1-trichloroethane 321.57
    2-aminoethanol 481.15
    morpholine-4-carbaldehyde 1796.87
    sulfolane 1058.82
    2,2,4-trimethylpentane 56.27
    2-methyltetrahydrofuran 596.58
    n-hexyl acetate 261.14
    isooctane 38.98
    2-(2-butoxyethoxy)ethanol 453.04
    sec-butyl acetate 217.7
    tert-butyl acetate 278.57
    decalin 66.45
    glycerin 378.38
    diglyme 977.27
    acrylic acid 393.63
    isopropyl myristate 145.11
    n-butyric acid 306.11
    acetyl acetate 306.37
    di(2-ethylhexyl) phthalate 128.86
    ethyl propionate 368.06
    nitromethane 1695.59
    1,2-diethoxyethane 443.02
    benzonitrile 351.53
    trioctyl phosphate 99.99
    1-bromopropane 363.11
    gamma-valerolactone 1155.51
    n-decanol 142.14
    triethyl phosphate 148.34
    4-methyl-2-pentanol 165.97
    propionitrile 527.13
    vinylene carbonate 385.71
    1,1,2-trichlorotrifluoroethane 549.76
    DMS 278.65
    cumene 159.79
    2-octanol 106.79
    2-hexanone 439.53
    octyl acetate 173.46
    limonene 157.87
    1,2-dimethoxyethane 1679.61
    ethyl orthosilicate 145.26
    tributyl phosphate 126.75
    diacetone alcohol 392.56
    N,N-dimethylaniline 531.9
    acrylonitrile 695.04
    aniline 328.5
    1,3-propanediol 455.68
    bromobenzene 156.42
    dibromomethane 467.75
    1,1,2,2-tetrachloroethane 501.93
    2-methyl-cyclohexyl acetate 179.93
    tetrabutyl urea 246.05
    diisobutyl methanol 110.39
    2-phenylethanol 206.78
    styrene 236.69
    dioctyl adipate 211.34
    dimethyl sulfate 648.9
    ethyl butyrate 253.61
    methyl lactate 355.51
    butyl lactate 166.9
    diethyl carbonate 185.12
    propanediol butyl ether 282.08
    triethyl orthoformate 192.27
    p-tert-butyltoluene 110.75
    methyl 4-tert-butylbenzoate 310.72
    morpholine 987.05
    tert-butylamine 408.74
    n-dodecanol 121.39
    dimethoxymethane 1519.45
    ethylene carbonate 316.59
    cyrene 414.96
    2-ethoxyethyl acetate 261.56
    2-ethylhexyl acetate 133.27
    1,2,4-trichlorobenzene 212.78
    4-methylpyridine 670.82
    dibutyl ether 249.99
    2,6-dimethyl-4-heptanol 110.39
    DEF 931.13
    dimethyl isosorbide 542.45
    tetrachloroethylene 359.22
    eugenol 324.76
    triacetin 316.27
    span 80 265.58
    1,4-butanediol 263.58
    1,1-dichloroethane 427.85
    2-methyl-1-pentanol 239.94
    methyl formate 1104.04
    2-methyl-1-butanol 292.88
    n-decane 57.16
    butyronitrile 432.18
    3,7-dimethyl-1-octanol 172.53
    1-chlorooctane 133.74
    1-chlorotetradecane 71.97
    n-nonane 57.11
    undecane 45.14
    tert-butylcyclohexane 57.53
    cyclooctane 60.35
    cyclopentanol 338.56
    tetrahydropyran 577.08
    tert-amyl methyl ether 408.96
    2,5,8-trioxanonane 756.97
    1-hexene 256.99
    2-isopropoxyethanol 498.52
    2,2,2-trifluoroethanol 420.83
    methyl butyrate 482.02

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction