1,2-Diaminopropane

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  • Identifiers

    CAS number
    78-90-0

    Molecular formula
    C3H10N2

    SMILES
    CC(CN)N

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 86.47%
    Cheesy 56.48%
    Ripe 48.55%
    Odorless 41.51%
    Animal 25.38%
    Meaty 17.68%
    Savory 15.46%
    Pungent 15.12%
    Musty 13.23%
    Cooked 12.9%

     

    Flavor
    Fishy 45.24%
    Ammoniacal 40.59%
    Sulfurous 31.2%
    Meaty 29.06%
    Ammonia 24.3%
    Sulfury 24.01%
    Glue 20.11%
    Odorless 20.04%
    Onion 19.97%
    Bloody 19.97%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    -1.2

    pKa est.
    5.66 (weak acid)

    Molecular weight
    74.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -35 °F (NTP, 1992)
    • -12 °C

    Boiling point

    • 248.9 °F at 760 mmHg (NTP, 1992)
    • 119 °C

    Flash point

    • 34.01 ˚C est.
    • 92 °F (NFPA, 2010)
    • 33 °C c.c.

    Solubility expt.

    • Very soluble (NTP, 1992)
    • Solubility in water: miscible

  • Synonyms

    • 1,2-DIAMINOPROPANE
    • Propylenediamine
    • 1,2-Propanediamine
    • 78-90-0
    • propane-1,2-diamine
    • Propylene diamine
    • 2,3-Diaminopropane
    • 1,2-Propylenediamine
    • 1-methylethylenediamine
    • CCRIS 4863
    • 10424-38-1
    • EINECS 201-155-9
    • NSC 175731
    • 1,2 Diaminopropane
    • BRN 0605274
    • 2A4P522UGO
    • DTXSID4021761
    • CHEBI:30630
    • AI3-11523
    • rac 1,2-Diaminopropane
    • Propane, 1,2-diamino-
    • (R)-Propane-1,2-diamine
    • NSC-175731
    • PROPYLENEDIAMINE [MI]
    • DTXCID701761
    • EC 201-155-9
    • N,N'-Dimethyl-1,2-diaminopropane
    • 4-04-00-01255 (Beilstein Handbook Reference)
    • MFCD00008089
    • (+/-)-1,2-DIAMINOPROPANE
    • 1,2-propane diamine
    • 2-methylethylenediamine
    • UNII-2A4P522UGO
    • 1,2diaminopropane
    • 1,2propanediamine
    • 2,3Diaminopropane
    • 2-Aminopropylamine
    • 1,2propylenediamine
    • 1,2-diamino-propane
    • 1,2-propylene diamine
    • 1,2-Trimethylenediamine
    • DL-1,2-Propanediamine
    • 1,2-Diamino-n-propane
    • methyl-ethane-1,2-diamine
    • (RS)-1,2-Propanediamine
    • 1-methyl-1,2-ethanediamine
    • 1,2-Diaminopropane, 99%
    • 1-Methyl-1,2-diaminoethane
    • WLN: ZY1&1Z
    • CHEMBL1319459
    • DL-1,2-PROPYLENEDIAMINE
    • (+-)-1,2-DIAMINOPROPANE
    • Tox21_202135
    • 1,2-Propanediamine, (.+/-.)-
    • BBL027674
    • NSC175731
    • STL372705
    • AKOS000119821
    • AKOS016042091
    • (.+-.)-1,2-DIAMINOPROPANE
    • SB33984
    • SB38321
    • UN 2258
    • CAS-78-90-0
    • 1,2-Diaminopropane 1,2-Proplenediamine
    • NCGC00090951-01
    • NCGC00090951-02
    • NCGC00259684-01
    • FD138906
    • DB-056342
    • D0113
    • NS00007190
    • EN300-19622
    • 1,2-Propylenediamine [UN2258] [Corrosive]
    • Q161461
    • B007CB1E-9CAC-43C8-A500-624DA1818ADC
    • F2191-0283
    • Z104474490
    • 201-155-9

  • Applications

    1,2-Diaminopropane (CAS 78-90-0) is commonly used as an epoxy resin curing agent and as a crosslinker for polyurethane/polyurea systems, supporting coatings, adhesives, and electronic encapsulation materials; it serves as a key intermediate in the synthesis of specialty chemicals for pharmaceuticals and agrochemicals; and it provides a building block for the preparation of chiral ligands used in metal-catalyzed asymmetric synthesis, as well as a precursor for polymer and plastic formulations in industrial applications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 39.75
    methanol 131.34
    isopropanol 10.77
    water 746.5
    ethyl acetate 6.64
    n-propanol 25.39
    acetone 6.89
    n-butanol 16.03
    acetonitrile 11.13
    DMF 27.81
    toluene 1.07
    isobutanol 12.98
    1,4-dioxane 6.32
    methyl acetate 7.83
    THF 20.76
    2-butanone 7.16
    n-pentanol 7.6
    sec-butanol 10.25
    n-hexane 0.47
    ethylene glycol 119.2
    NMP 103.34
    cyclohexane 0.76
    DMSO 41.04
    n-butyl acetate 10.9
    n-octanol 2.78
    chloroform 8.45
    n-propyl acetate 4.41
    acetic acid 344.71
    dichloromethane 5.38
    cyclohexanone 16.25
    propylene glycol 84.53
    isopropyl acetate 3.26
    DMAc 33.12
    2-ethoxyethanol 27.66
    isopentanol 8.11
    n-heptane 1.24
    ethyl formate 22.7
    1,2-dichloroethane 2.23
    n-hexanol 13.65
    2-methoxyethanol 69.72
    isobutyl acetate 2.43
    tetrachloromethane 5.52
    n-pentyl acetate 4.67
    transcutol 24.48
    n-heptanol 8.42
    ethylbenzene 0.48
    MIBK 2.1
    2-propoxyethanol 42.08
    tert-butanol 7.56
    MTBE 2.01
    2-butoxyethanol 27.9
    propionic acid 96.77
    o-xylene 1.13
    formic acid 699.47
    diethyl ether 1.9
    m-xylene 1.02
    p-xylene 0.93
    chlorobenzene 2.63
    dimethyl carbonate 4.9
    n-octane 0.33
    formamide 265.46
    cyclopentanone 34.63
    2-pentanone 4.74
    anisole 1.49
    cyclopentyl methyl ether 7.75
    gamma-butyrolactone 64.39
    1-methoxy-2-propanol 26.85
    pyridine 10.48
    3-pentanone 4.03
    furfural 74.99
    n-dodecane 0.16
    diethylene glycol 64.69
    diisopropyl ether 0.64
    tert-amyl alcohol 9.54
    acetylacetone 5.8
    n-hexadecane 0.16
    acetophenone 3.32
    methyl propionate 8.13
    isopentyl acetate 6.82
    trichloroethylene 7.62
    n-nonanol 2.55
    cyclohexanol 12.02
    benzyl alcohol 6.35
    2-ethylhexanol 6.87
    isooctanol 5.2
    dipropyl ether 3.42
    1,2-dichlorobenzene 2.61
    ethyl lactate 9.65
    propylene carbonate 32.45
    n-methylformamide 76.06
    2-pentanol 5.22
    n-pentane 0.53
    1-propoxy-2-propanol 25.2
    1-methoxy-2-propyl acetate 9.71
    2-(2-methoxypropoxy) propanol 10.14
    mesitylene 0.68
    ε-caprolactone 22.97
    p-cymene 1.54
    epichlorohydrin 15.88
    1,1,1-trichloroethane 2.77
    2-aminoethanol 125.23
    morpholine-4-carbaldehyde 45.29
    sulfolane 88.69
    2,2,4-trimethylpentane 0.43
    2-methyltetrahydrofuran 10.92
    n-hexyl acetate 3.51
    isooctane 0.19
    2-(2-butoxyethoxy)ethanol 16.09
    sec-butyl acetate 2.05
    tert-butyl acetate 2.67
    decalin 0.33
    glycerin 184.27
    diglyme 20.13
    acrylic acid 134.07
    isopropyl myristate 1.03
    n-butyric acid 81.28
    acetyl acetate 6.85
    di(2-ethylhexyl) phthalate 4.06
    ethyl propionate 3.45
    nitromethane 106.19
    1,2-diethoxyethane 2.78
    benzonitrile 6.09
    trioctyl phosphate 3.26
    1-bromopropane 1.2
    gamma-valerolactone 50.45
    n-decanol 1.85
    triethyl phosphate 4.0
    4-methyl-2-pentanol 2.53
    propionitrile 7.71
    vinylene carbonate 27.04
    1,1,2-trichlorotrifluoroethane 84.7
    DMS 3.92
    cumene 0.57
    2-octanol 2.65
    2-hexanone 2.78
    octyl acetate 2.16
    limonene 2.24
    1,2-dimethoxyethane 10.1
    ethyl orthosilicate 3.96
    tributyl phosphate 3.62
    diacetone alcohol 10.2
    N,N-dimethylaniline 1.63
    acrylonitrile 15.17
    aniline 8.15
    1,3-propanediol 87.96
    bromobenzene 1.55
    dibromomethane 3.12
    1,1,2,2-tetrachloroethane 6.13
    2-methyl-cyclohexyl acetate 5.1
    tetrabutyl urea 3.88
    diisobutyl methanol 2.21
    2-phenylethanol 8.13
    styrene 0.66
    dioctyl adipate 2.29
    dimethyl sulfate 12.31
    ethyl butyrate 6.71
    methyl lactate 25.36
    butyl lactate 12.41
    diethyl carbonate 3.85
    propanediol butyl ether 21.09
    triethyl orthoformate 5.47
    p-tert-butyltoluene 1.39
    methyl 4-tert-butylbenzoate 6.98
    morpholine 13.64
    tert-butylamine 3.48
    n-dodecanol 1.33
    dimethoxymethane 6.23
    ethylene carbonate 18.94
    cyrene 21.13
    2-ethoxyethyl acetate 5.94
    2-ethylhexyl acetate 5.4
    1,2,4-trichlorobenzene 3.67
    4-methylpyridine 6.66
    dibutyl ether 1.2
    2,6-dimethyl-4-heptanol 2.21
    DEF 11.17
    dimethyl isosorbide 18.44
    tetrachloroethylene 10.7
    eugenol 10.7
    triacetin 6.27
    span 80 16.81
    1,4-butanediol 31.71
    1,1-dichloroethane 1.91
    2-methyl-1-pentanol 5.32
    methyl formate 41.82
    2-methyl-1-butanol 11.11
    n-decane 0.27
    butyronitrile 7.38
    3,7-dimethyl-1-octanol 2.22
    1-chlorooctane 0.63
    1-chlorotetradecane 0.28
    n-nonane 0.27
    undecane 0.2
    tert-butylcyclohexane 0.32
    cyclooctane 0.38
    cyclopentanol 26.88
    tetrahydropyran 4.76
    tert-amyl methyl ether 2.3
    2,5,8-trioxanonane 15.4
    1-hexene 0.92
    2-isopropoxyethanol 11.16
    2,2,2-trifluoroethanol 171.48
    methyl butyrate 6.05

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction