1,1,4,4-Tetramethyltetralin

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  • Identifiers

    CAS number
    6683-46-1

    Molecular formula
    C14H20

    SMILES
    CC1(CCC(C2=CC=CC=C21)(C)C)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Woody 66.73%
    Sweet 49.62%
    Dry 44.06%
    Musk 42.24%
    Spicy 39.65%
    Amber 39.47%
    Fruity 36.21%
    Camphoreous 32.8%
    Earthy 29.76%
    Tobacco 29.16%

     

    Flavor
    Camphor 42.49%
    Woody 37.27%
    Dry 30.3%
    Pine 24.61%
    Sweet 23.22%
    Earthy 21.67%
    Old paper 21.23%
    Cedar 20.99%
    Fir needle 20.54%
    Plastic 20.45%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    5.0

    pKa est.
    8.32 (weak base)

    Molecular weight
    188.31 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    230°C

    Flash point

    • 109.65 ˚C est.

  • Synonyms

    • 6683-46-1
    • 1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene
    • 1,2,3,4-Tetrahydro-1,1,4,4-tetramethylnaphthalene
    • 1,1,4,4-tetramethyltetralin
    • NSC 17400
    • YKU41EDL5Y
    • Naphthalene, 1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-
    • EINECS 229-723-1
    • NSC-17400
    • DTXSID6064452
    • RefChem:409660
    • DTXCID2044846
    • 229-723-1
    • MFCD00052728
    • 1,1,4,4-tetramethyl-2,3-dihydronaphthalene
    • Naphthalene,1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-
    • 1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-naphthalene
    • 1,1,4,4-Tetramethyl-1,2,3,4-tetrahydronaphthalene; 1,1,4,4-Tetramethyltetralin
    • NSC17400
    • UNII-YKU41EDL5Y
    • SCHEMBL501768
    • CHEMBL540753
    • SCHEMBL1599532
    • SCHEMBL2014128
    • SCHEMBL8308882
    • SCHEMBL29608943
    • CS-B1804
    • SBB090834
    • AKOS006227803
    • GS-3790
    • AC-25626
    • SY101066
    • DB-005610
    • NS00036071
    • ST50407273
    • C11440
    • EN300-142446
    • F210048
    • 1,2,3,4-tetrahydro-1,1,4,4tetramethylnaphthalene
    • 1,1,4,4-tetramethyl-1,2,3,4-tetrahydro naphthalene
    • 1,1,4,4-tetramethyl-1,2,3,4-tetrahydro-naphthalene
    • 1,1,4,4-tetramethyl1,2,3,4-tetrahydro naphthalene
    • 5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalene
    • 5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-naphthalene
    • 5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalene
    • 6683-46-1

  • Applications

    1,1,4,4-Tetramethyltetralin (CAS 6683-46-1) is a non-polar hydrocarbon primarily used as an industrial solvent and processing aid. In coatings, inks, and adhesives it can act as a diluent or co-solvent to improve wetting and control viscosity during formulation. It is commonly evaluated as an intermediate in organic synthesis, providing a rigid, hydrogen-rich tetralin-derived scaffold for building more complex molecules. In polymer and plastics processing it may serve as a processing solvent or carrier for additives. The fragrance industry may consider it as a potential fragrance ingredient or fixative due to its alicyclic hydrocarbon character, while in laboratory settings it can function as a non-polar reference compound or solvent for physicochemical studies. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 55.73
    methanol 41.67
    isopropanol 65.85
    water 0.08
    ethyl acetate 355.94
    n-propanol 84.17
    acetone 339.16
    n-butanol 96.52
    acetonitrile 142.0
    DMF 581.84
    toluene 462.26
    isobutanol 84.29
    1,4-dioxane 654.39
    methyl acetate 319.9
    THF 1343.07
    2-butanone 393.12
    n-pentanol 87.04
    sec-butanol 86.92
    n-hexane 230.57
    ethylene glycol 11.23
    NMP 717.13
    cyclohexane 279.4
    DMSO 203.81
    n-butyl acetate 609.28
    n-octanol 182.84
    chloroform 728.05
    n-propyl acetate 300.83
    acetic acid 46.66
    dichloromethane 640.24
    cyclohexanone 863.29
    propylene glycol 21.02
    isopropyl acetate 339.8
    DMAc 527.41
    2-ethoxyethanol 111.24
    isopentanol 107.48
    n-heptane 248.01
    ethyl formate 163.41
    1,2-dichloroethane 518.59
    n-hexanol 268.58
    2-methoxyethanol 135.63
    isobutyl acetate 307.37
    tetrachloromethane 204.11
    n-pentyl acetate 342.42
    transcutol 323.68
    n-heptanol 160.5
    ethylbenzene 357.17
    MIBK 325.49
    2-propoxyethanol 339.26
    tert-butanol 118.33
    MTBE 361.09
    2-butoxyethanol 202.01
    propionic acid 84.48
    o-xylene 347.96
    formic acid 8.5
    diethyl ether 384.32
    m-xylene 389.87
    p-xylene 422.59
    chlorobenzene 439.78
    dimethyl carbonate 228.79
    n-octane 130.21
    formamide 21.21
    cyclopentanone 1104.54
    2-pentanone 399.76
    anisole 439.89
    cyclopentyl methyl ether 805.4
    gamma-butyrolactone 868.57
    1-methoxy-2-propanol 156.61
    pyridine 476.35
    3-pentanone 440.34
    furfural 513.69
    n-dodecane 89.18
    diethylene glycol 122.13
    diisopropyl ether 252.88
    tert-amyl alcohol 130.32
    acetylacetone 462.91
    n-hexadecane 106.58
    acetophenone 369.1
    methyl propionate 355.84
    isopentyl acetate 557.47
    trichloroethylene 840.71
    n-nonanol 175.39
    cyclohexanol 204.04
    benzyl alcohol 167.75
    2-ethylhexanol 265.83
    isooctanol 143.81
    dipropyl ether 561.05
    1,2-dichlorobenzene 448.52
    ethyl lactate 128.28
    propylene carbonate 492.56
    n-methylformamide 131.91
    2-pentanol 104.68
    n-pentane 127.94
    1-propoxy-2-propanol 306.3
    1-methoxy-2-propyl acetate 531.06
    2-(2-methoxypropoxy) propanol 213.96
    mesitylene 317.37
    ε-caprolactone 632.88
    p-cymene 300.51
    epichlorohydrin 790.73
    1,1,1-trichloroethane 667.96
    2-aminoethanol 24.19
    morpholine-4-carbaldehyde 664.16
    sulfolane 877.38
    2,2,4-trimethylpentane 83.35
    2-methyltetrahydrofuran 808.82
    n-hexyl acetate 496.57
    isooctane 77.98
    2-(2-butoxyethoxy)ethanol 230.52
    sec-butyl acetate 277.87
    tert-butyl acetate 425.43
    decalin 194.25
    glycerin 28.48
    diglyme 502.52
    acrylic acid 71.05
    isopropyl myristate 272.6
    n-butyric acid 138.34
    acetyl acetate 269.65
    di(2-ethylhexyl) phthalate 163.98
    ethyl propionate 332.66
    nitromethane 175.27
    1,2-diethoxyethane 410.63
    benzonitrile 279.97
    trioctyl phosphate 156.29
    1-bromopropane 429.57
    gamma-valerolactone 901.28
    n-decanol 147.35
    triethyl phosphate 251.43
    4-methyl-2-pentanol 97.67
    propionitrile 198.43
    vinylene carbonate 401.7
    1,1,2-trichlorotrifluoroethane 280.57
    DMS 472.54
    cumene 273.3
    2-octanol 142.19
    2-hexanone 338.92
    octyl acetate 297.4
    limonene 410.13
    1,2-dimethoxyethane 432.61
    ethyl orthosilicate 230.2
    tributyl phosphate 192.39
    diacetone alcohol 257.46
    N,N-dimethylaniline 371.27
    acrylonitrile 213.71
    aniline 226.01
    1,3-propanediol 45.35
    bromobenzene 604.12
    dibromomethane 477.05
    1,1,2,2-tetrachloroethane 745.83
    2-methyl-cyclohexyl acetate 415.91
    tetrabutyl urea 273.71
    diisobutyl methanol 189.05
    2-phenylethanol 300.63
    styrene 364.43
    dioctyl adipate 282.66
    dimethyl sulfate 347.73
    ethyl butyrate 442.69
    methyl lactate 134.7
    butyl lactate 200.18
    diethyl carbonate 302.13
    propanediol butyl ether 136.53
    triethyl orthoformate 324.81
    p-tert-butyltoluene 315.96
    methyl 4-tert-butylbenzoate 363.01
    morpholine 537.19
    tert-butylamine 110.52
    n-dodecanol 128.02
    dimethoxymethane 439.02
    ethylene carbonate 361.62
    cyrene 253.54
    2-ethoxyethyl acetate 341.93
    2-ethylhexyl acetate 565.06
    1,2,4-trichlorobenzene 467.52
    4-methylpyridine 557.44
    dibutyl ether 458.85
    2,6-dimethyl-4-heptanol 189.05
    DEF 463.89
    dimethyl isosorbide 580.33
    tetrachloroethylene 445.67
    eugenol 253.87
    triacetin 348.22
    span 80 203.57
    1,4-butanediol 27.04
    1,1-dichloroethane 497.69
    2-methyl-1-pentanol 105.05
    methyl formate 154.18
    2-methyl-1-butanol 105.81
    n-decane 140.75
    butyronitrile 207.91
    3,7-dimethyl-1-octanol 192.13
    1-chlorooctane 321.86
    1-chlorotetradecane 157.94
    n-nonane 152.27
    undecane 110.59
    tert-butylcyclohexane 178.38
    cyclooctane 188.76
    cyclopentanol 208.2
    tetrahydropyran 757.91
    tert-amyl methyl ether 343.44
    2,5,8-trioxanonane 342.29
    1-hexene 333.38
    2-isopropoxyethanol 121.9
    2,2,2-trifluoroethanol 34.97
    methyl butyrate 397.29

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction