1,1,2,2-Tetrachloroethane

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  • Identifiers

    CAS number
    79-34-5

    Molecular formula
    C2H2Cl4

    SMILES
    C(C(Cl)Cl)(Cl)Cl

    Safety labels

    Acute Toxic
    Acute Toxic

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 52.19%
    Fishy 33.25%
    Woody 24.55%
    Sweet 22.73%
    Animal 18.65%
    Oily 18.02%
    Balsamic 17.78%
    Cooling 16.75%
    Waxy 16.13%
    Ripe 15.67%

     

    Flavor
    Odorless 34.21%
    Sulfurous 25.07%
    Sulfury 20.33%
    Meaty 19.31%
    Bloody 18.92%
    Glue 18.88%
    Mild 18.51%
    Bland 18.27%
    Skunky 18.15%
    Bouillon 17.96%

     

    Odor impact est.
    Medium

    Odor threshold

    • Odor Threshold Low: 0.23 [mmHg]. Odor Threshold High: 7.9 [mmHg]. Detection odor threshold from AIHA (mean = 7.3 ppm)
    • The odor threshold in air is 1.5 ppm.
    • Low: 21.0 mg/cu m; High: 35.0 mg/cu m.
    • The odor warning when the exposure limit value is exceeded is insufficient.

  • Properties

    XLogP3-AA
    2.4

    pKa est.
    4.25 (weak acid)

    Molecular weight
    167.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -33 °F (NTP, 1992)
    • -42.3 °C
    • Liquid molar volume = 0.105754 cu m/kmol; Heat of fusion at melting point = 9.172X10+06 J/kmol
    • -42,5 °C
    • -33 °F

    Boiling point

    • 295 °F at 760 mmHg (NTP, 1992)
    • 146.0 °C
    • 146 °C
    • 295 °F
    • 296 °F

    Flash point

    • 56.21 ˚C est.

    Solubility expt.

    • less than 0.1 mg/mL at 72 °F (NTP, 1992)
    • For more Solubility (Complete) data for 1,1,2,2-TETRACHLOROETHANE (9 total), please visit the HSDB record page.
    • In water, 2,830 mg/L at 25 °C
    • In water, 2,900 mg/L at 20 °C.
    • One gram dissolves in 350 mL of water at 25 °C
    • Soluble in acetone; miscible in ether and ethanol
    • Miscible with methanol, benzene, petroleum ether, carbon tetrachloride, chloroform, carbon disulfide, dimethylformamide and oils
    • Solubility in water, g/100ml at 20 °C: 0.29
    • 0.3%

  • Synonyms

    • 1,1,2,2-TETRACHLOROETHANE
    • 79-34-5
    • Tetrachloroethane
    • s-Tetrachloroethane
    • Acetylene tetrachloride
    • Ethane, 1,1,2,2-tetrachloro-
    • sym-Tetrachloroethane
    • Bonoform
    • Cellon
    • Tetrachlorethane
    • Westron
    • 1,1,2,2-Tetrachlorethane
    • 1,1,2,2-Tetrachloraethan
    • 1,1-Dichloro-2,2-dichloroethane
    • Tetrachlorure d'acetylene
    • RCRA waste number U209
    • NCI-C03554
    • Dichloro-2,2-dichloroethane
    • Tetrachloroethane [ISO]
    • Tetrachloroethane, 1,1,2,2-
    • 1,1,2,2-Tetracloroetano
    • 1,1,2,2-Czterochloroetan
    • NSC 60912
    • 1,1,2,2-Tetrachloorethaan
    • 1,1,2,2-Tetrachloro-Ethane
    • 1L6BI049XV
    • DTXSID7021318
    • CHEBI:36026
    • NSC-60912
    • TCE (ambiguous)
    • Caswell No. 826
    • Acetosol
    • Tetrachloroethane (VAN)
    • CCRIS 578
    • HSDB 123
    • Tetrachlorure d'acetylene [French]
    • EINECS 201-197-8
    • 1,1,2,2-Czterochloroetan [Polish]
    • 1,1,2,2-Tetrachloorethaan [Dutch]
    • 1,1,2,2-Tetrachloraethan [German]
    • 1,1,2,2-Tetrachlorethane [French]
    • 1,1,2,2-Tetracloroetano [Italian]
    • RCRA waste no. U209
    • EPA Pesticide Chemical Code 078601
    • BRN 0969206
    • UNII-1L6BI049XV
    • AI3-04597
    • sym-tetrachlorethane
    • MFCD00000848
    • CHCl2CHCl2
    • WLN: GYGYGG
    • R 130 (refrigerant)
    • 1,2,2-Tetracloroetano
    • 1,2,2-Czterochloroetan
    • 1,2,2-Tetrachloraethan
    • 1,2,2-Tetrachlorethane
    • 1,2,2-Tetrachloorethaan
    • 1,2,2-Tetrachloroethane
    • SCHEMBL2564
    • (CHCl2)2
    • Ethane,1,2,2-tetrachloro-
    • 4-01-00-00144 (Beilstein Handbook Reference)
    • CHEMBL47258
    • TETRACHLOROETHANE [MI]
    • 1,1,2,2,-tetrachloroethane
    • 1,1,2,2-tetra chloroethane
    • DTXCID201318
    • TETRACHLOROETHANE [HSDB]
    • NSC60912
    • 1,1,2,2-tetrakis(chloranyl)ethane
    • Tox21_200074
    • AKOS009029114
    • ETHANE,1,1,2,2-TETRACHLORO
    • UN 1702
    • 1,1,2,2-TCE
    • CAS-79-34-5
    • NCGC00091543-01
    • NCGC00091543-02
    • NCGC00257628-01
    • 1,1,2,2-TETRACHLOROETHANE [IARC]
    • NS00010827
    • S0654
    • T0063
    • EN300-19275
    • C19534
    • 1,1,2,2-Tetrachloroethane, analytical standard
    • 1,1,2,2-Tetrachloroethane, reagent grade, 97%
    • A839654
    • Q161275
    • InChI=1/C2H2Cl4/c3-1(4)2(5)6/h1-2
    • 1 pound not1 pound not2 pound not2-tetrachloroethane
    • 1,1,2,2-Tetrachloroethane, reagent grade, >=98.0%
    • 1,1,2,2-Tetrachloroethane 100 microg/mL in Methanol
    • F0001-2074
    • 1,1,2,2-Tetrachloroethane, JIS special grade, >=97.0%

  • Applications

    1,1,2,2-Tetrachloroethane is primarily used as a chlorinated organic solvent and as an intermediate in the manufacture of other chlorinated compounds. In industry, it has been employed as a solvent for resins, waxes, oils, and specialty coatings, as well as a processing solvent for adhesives and inks. It can serve as a feedstock or reagent in the synthesis of halogenated derivatives used in polymers and electronics-related chemistries. Historically it has been evaluated for degreasing and cleaning applications in manufacturing, though its handling is subject to local regulations due to toxicity and environmental concerns. In some contexts it may be used in production of specialty chemicals or chlorinated solvents, depending on formulation requirements and regulatory limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 16.63
    methanol 17.6
    isopropanol 13.44
    water 1.84
    ethyl acetate 36.73
    n-propanol 15.47
    acetone 73.65
    n-butanol 15.45
    acetonitrile 37.54
    DMF 153.42
    toluene 36.17
    isobutanol 12.46
    1,4-dioxane 88.88
    methyl acetate 48.33
    THF 136.33
    2-butanone 53.59
    n-pentanol 15.56
    sec-butanol 15.96
    n-hexane 11.05
    ethylene glycol 10.39
    NMP 244.5
    cyclohexane 34.64
    DMSO 181.17
    n-butyl acetate 52.18
    n-octanol 21.72
    chloroform 110.45
    n-propyl acetate 38.43
    acetic acid 38.99
    dichloromethane 106.02
    cyclohexanone 107.04
    propylene glycol 8.46
    isopropyl acetate 30.81
    DMAc 154.38
    2-ethoxyethanol 37.12
    isopentanol 15.19
    n-heptane 26.23
    ethyl formate 35.06
    1,2-dichloroethane 75.39
    n-hexanol 21.58
    2-methoxyethanol 45.98
    isobutyl acetate 26.05
    tetrachloromethane 32.9
    n-pentyl acetate 38.36
    transcutol 112.64
    n-heptanol 18.1
    ethylbenzene 25.97
    MIBK 33.81
    2-propoxyethanol 43.67
    tert-butanol 19.58
    MTBE 32.25
    2-butoxyethanol 33.23
    propionic acid 22.3
    o-xylene 40.74
    formic acid 18.79
    diethyl ether 38.78
    m-xylene 27.6
    p-xylene 38.83
    chlorobenzene 52.88
    dimethyl carbonate 30.02
    n-octane 11.62
    formamide 37.27
    cyclopentanone 125.02
    2-pentanone 45.86
    anisole 48.66
    cyclopentyl methyl ether 74.77
    gamma-butyrolactone 119.65
    1-methoxy-2-propanol 36.39
    pyridine 91.94
    3-pentanone 48.58
    furfural 141.02
    n-dodecane 8.11
    diethylene glycol 36.69
    diisopropyl ether 19.86
    tert-amyl alcohol 20.9
    acetylacetone 74.08
    n-hexadecane 9.16
    acetophenone 69.38
    methyl propionate 38.29
    isopentyl acetate 43.73
    trichloroethylene 139.85
    n-nonanol 21.98
    cyclohexanol 34.57
    benzyl alcohol 36.32
    2-ethylhexanol 25.93
    isooctanol 16.88
    dipropyl ether 52.86
    1,2-dichlorobenzene 60.85
    ethyl lactate 23.5
    propylene carbonate 61.91
    n-methylformamide 46.91
    2-pentanol 14.62
    n-pentane 12.41
    1-propoxy-2-propanol 44.27
    1-methoxy-2-propyl acetate 55.05
    2-(2-methoxypropoxy) propanol 48.1
    mesitylene 24.69
    ε-caprolactone 81.59
    p-cymene 37.62
    epichlorohydrin 105.26
    1,1,1-trichloroethane 67.23
    2-aminoethanol 13.03
    morpholine-4-carbaldehyde 160.61
    sulfolane 197.05
    2,2,4-trimethylpentane 8.09
    2-methyltetrahydrofuran 89.47
    n-hexyl acetate 41.22
    isooctane 5.5
    2-(2-butoxyethoxy)ethanol 51.19
    sec-butyl acetate 28.52
    tert-butyl acetate 39.46
    decalin 14.66
    glycerin 16.7
    diglyme 118.14
    acrylic acid 28.22
    isopropyl myristate 27.05
    n-butyric acid 26.76
    acetyl acetate 36.66
    di(2-ethylhexyl) phthalate 26.77
    ethyl propionate 34.37
    nitromethane 85.28
    1,2-diethoxyethane 64.84
    benzonitrile 53.96
    trioctyl phosphate 20.7
    1-bromopropane 42.5
    gamma-valerolactone 135.46
    n-decanol 18.49
    triethyl phosphate 36.89
    4-methyl-2-pentanol 12.14
    propionitrile 26.35
    vinylene carbonate 58.35
    1,1,2-trichlorotrifluoroethane 91.62
    DMS 47.86
    cumene 22.17
    2-octanol 16.64
    2-hexanone 44.11
    octyl acetate 30.44
    limonene 57.72
    1,2-dimethoxyethane 94.62
    ethyl orthosilicate 36.24
    tributyl phosphate 25.52
    diacetone alcohol 42.08
    N,N-dimethylaniline 57.59
    acrylonitrile 37.39
    aniline 37.55
    1,3-propanediol 16.21
    bromobenzene 53.12
    dibromomethane 79.26
    1,1,2,2-tetrachloroethane 117.43
    2-methyl-cyclohexyl acetate 47.75
    tetrabutyl urea 46.29
    diisobutyl methanol 24.3
    2-phenylethanol 40.0
    styrene 32.57
    dioctyl adipate 42.84
    dimethyl sulfate 69.15
    ethyl butyrate 52.7
    methyl lactate 26.31
    butyl lactate 31.79
    diethyl carbonate 36.34
    propanediol butyl ether 30.42
    triethyl orthoformate 46.65
    p-tert-butyltoluene 36.34
    methyl 4-tert-butylbenzoate 60.74
    morpholine 82.47
    tert-butylamine 16.33
    n-dodecanol 16.45
    dimethoxymethane 68.33
    ethylene carbonate 44.29
    cyrene 66.9
    2-ethoxyethyl acetate 48.21
    2-ethylhexyl acetate 42.98
    1,2,4-trichlorobenzene 80.76
    4-methylpyridine 81.51
    dibutyl ether 39.83
    2,6-dimethyl-4-heptanol 24.3
    DEF 80.96
    dimethyl isosorbide 108.21
    tetrachloroethylene 91.96
    eugenol 52.42
    triacetin 58.75
    span 80 42.12
    1,4-butanediol 10.84
    1,1-dichloroethane 53.37
    2-methyl-1-pentanol 16.05
    methyl formate 47.68
    2-methyl-1-butanol 14.87
    n-decane 12.59
    butyronitrile 26.38
    3,7-dimethyl-1-octanol 24.12
    1-chlorooctane 27.98
    1-chlorotetradecane 15.33
    n-nonane 13.29
    undecane 9.73
    tert-butylcyclohexane 10.94
    cyclooctane 17.09
    cyclopentanol 39.29
    tetrahydropyran 71.82
    tert-amyl methyl ether 36.69
    2,5,8-trioxanonane 93.2
    1-hexene 19.81
    2-isopropoxyethanol 30.25
    2,2,2-trifluoroethanol 28.42
    methyl butyrate 45.3

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction