1,1,2,2-Tetrachloro-1,2-difluoroethane

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  • Identifiers

    CAS number
    76-12-0

    Molecular formula
    C2Cl4F2

    SMILES
    C(C(F)(Cl)Cl)(F)(Cl)Cl

    Safety labels

    Irritant
    Irritant

  • Odor profile

    odorless 49.4%
    woody 29.29%
    sweet 26.78%
    balsamic 23.66%
    fishy 21.39%
    dry 19.71%
    clean 19.04%
    animal 17.6%
    amber 17.19%
    waxy 17.11%

    Scent© AI

  • Properties

    XLogP3-AA
    3.4 Well soluble in BB, DEP, IAA

    Molecular weight
    203.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • 77 °F (NIOSH, 2024)
    • 26 °C
    • 77 °F

    Boiling point

    • 199 °F at 760 mmHg (NIOSH, 2024)
    • 92.8 °C
    • 93 °C
    • 199 °F

    Solubility expt.

    • 0.01 % at 77 °F (NIOSH, 2024)
    • In water, 120 mg/L at 25 °C
    • Soluble in ethanol, ethyl ether, chloroform
    • Solubility in water, g/100ml: 0.012
    • (77 °F): 0.01%

  • Synonyms

    • 76-12-0
    • 1,1,2,2-Tetrachloro-1,2-difluoroethane
    • 1,2-Difluorotetrachloroethane
    • Freon R 112
    • Daiflon 112
    • Daiflon S2
    • Refrigerant 112
    • Halocarbon 112
    • Genetron 112
    • Tetrachloro-1,2-difluoroethane
    • sym-Tetrachlorodifluoroethane
    • 1,2-Difluoro-1,1,2,2-tetrachloroethane
    • Fluorocarbon 112
    • Ucon 112
    • FREON 112
    • R 112
    • CFC-112
    • Ethane, 1,1,2,2-tetrachloro-1,2-difluoro-
    • FC 112
    • HSDB 144
    • F-112
    • EINECS 200-935-6
    • Ethane, 1,2-difluoro-1,1,2,2-tetrachloro-
    • BRN 1740336
    • H155PU1V8F
    • DTXSID5026091
    • Ethane,1,1,2,2-tetrachloro-1,2-difluoro-
    • 1,1,2,2-Tetrachlorodifluoroethane
    • s-Tetrachlorodifluoroethane
    • DTXCID706091
    • EC 200-935-6
    • 1,1,2,2-TETRACHLORO-1,2-DIFLUOROETHANE [HSDB]
    • UNII-H155PU1V8F
    • Freon112
    • CFCl2CFCl2
    • Difluorotetrachloroethane
    • DAIFLON S 2
    • symTetrachlorodifluoroethane
    • Tetrachloro1,2difluoroethane
    • SCHEMBL74197
    • CFC112
    • FRON 112
    • CHEMBL3186694
    • UGCSPKPEHQEOSR-UHFFFAOYSA-
    • CFC 112
    • Tox21_200566
    • MFCD00039322
    • 1,2Difluoro1,1,2,2tetrachloroethane
    • CAS-76-12-0
    • NCGC00248707-01
    • NCGC00258120-01
    • 1,2-Difluorotetrachloroethane (CFC-112)
    • DB-056024
    • F 112
    • NS00003480
    • A838615
    • InChI=1/C2Cl4F2/c3-1(4,7)2(5,6)8
    • Q2806548
    • 1,1,2,2-Tetrachloro-1,2-difluoroethane (ACGIH:OSHA)
    • 1,1,2,2-tetrakis(chloranyl)-1,2-bis(fluoranyl)ethane
    • 200-935-6
1 4

IFRA Standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction