1,1,1,5,5,5-Hexamethyl-3-propyl-3-[(trimethylsilyl)oxy]trisiloxane

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  • Identifiers

    CAS number
    60111-46-8

    Molecular formula
    C12H34O3Si4

    SMILES
    CCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

    Safety labels

  • Odor profile

    Fragrance
    Green 35.57%
    Mint 31.79%
    Odorless 30.67%
    Alcoholic 27.13%
    Cooling 24.31%
    Fresh 24.18%
    Ethereal 22.33%
    Fermented 22.11%
    Camphoreous 21.93%
    Woody 21.73%

     

    Flavor
    Green 36.59%
    Mild 25.18%
    Pungent 22.85%
    Fruity 22.78%
    Sweet 22.77%
    Earthy 22.4%
    Bitter 21.63%
    Rose acetate 21.08%
    Catty 20.62%
    Citrus 20.49%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    8.01 (weak base)

    Molecular weight
    338.74 g/mol

    Flash point

    • 77.43 ˚C est.

  • Synonyms

    • 60111-46-8
    • propyltris(trimethylsiloxy)silane
    • 1,1,1,5,5,5-hexamethyl-3-propyl-3-[(trimethylsilyl)oxy]trisiloxane
    • trimethyl-[propyl-bis(trimethylsilyloxy)silyl]oxysilane
    • SCHEMBL226428
    • SCHEMBL339637
    • SCHEMBL373209
    • SCHEMBL5397307
    • DTXSID00462462
    • DB-256020
    • 60111-46-8

  • Applications

    Chemical name: 1,1,1,5,5,5-Hexamethyl-3-propyl-3-[(trimethylsilyl)oxy]trisiloxane; CAS number: 60111-46-8 is a siloxane-based molecule commonly used as an intermediate in silicone polymer synthesis and as a crosslinking/chain-extending agent for silicone elastomers and resins, helping tailor cure behavior, mechanical properties, and thermal stability. It also serves as a surface modifier and adhesion promoter in coatings, inks, and adhesives to improve wetting, adhesion, and surface durability. As a siloxane with an OTMS-protected alcohol functionality, it provides a handle for post-synthesis functionalization and may be used as a precursor for controlled surface treatments in electronics and optics to achieve targeted wettability. Additionally, it can act as a processing additive in polymer formulations to influence rheology and processing, serving as a building block for specialty silicone formulations in industrial manufacturing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 385.8
    methanol 336.13
    isopropanol 439.55
    water 8.02
    ethyl acetate 421.63
    n-propanol 464.02
    acetone 610.46
    n-butanol 449.44
    acetonitrile 227.04
    DMF 992.84
    toluene 515.92
    isobutanol 386.32
    1,4-dioxane 683.71
    methyl acetate 401.36
    THF 1932.0
    2-butanone 564.71
    n-pentanol 394.71
    sec-butanol 485.74
    n-hexane 297.43
    ethylene glycol 120.05
    NMP 1486.85
    cyclohexane 518.25
    DMSO 879.69
    n-butyl acetate 515.97
    n-octanol 514.52
    chloroform 1346.37
    n-propyl acetate 411.46
    acetic acid 370.44
    dichloromethane 987.44
    cyclohexanone 1159.06
    propylene glycol 292.25
    isopropyl acetate 389.05
    DMAc 856.15
    2-ethoxyethanol 348.62
    isopentanol 360.56
    n-heptane 287.63
    ethyl formate 321.5
    1,2-dichloroethane 607.96
    n-hexanol 537.34
    2-methoxyethanol 527.36
    isobutyl acetate 358.03
    tetrachloromethane 280.64
    n-pentyl acetate 542.57
    transcutol 563.79
    n-heptanol 425.29
    ethylbenzene 339.0
    MIBK 417.35
    2-propoxyethanol 625.1
    tert-butanol 495.99
    MTBE 379.91
    2-butoxyethanol 480.11
    propionic acid 414.24
    o-xylene 335.06
    formic acid 122.55
    diethyl ether 417.49
    m-xylene 380.52
    p-xylene 425.48
    chlorobenzene 560.17
    dimethyl carbonate 280.61
    n-octane 181.55
    formamide 185.29
    cyclopentanone 1540.33
    2-pentanone 544.95
    anisole 468.99
    cyclopentyl methyl ether 925.54
    gamma-butyrolactone 1379.38
    1-methoxy-2-propanol 639.64
    pyridine 800.36
    3-pentanone 428.06
    furfural 1035.11
    n-dodecane 135.82
    diethylene glycol 330.36
    diisopropyl ether 240.48
    tert-amyl alcohol 455.93
    acetylacetone 607.61
    n-hexadecane 148.25
    acetophenone 498.32
    methyl propionate 456.46
    isopentyl acetate 449.82
    trichloroethylene 1051.55
    n-nonanol 465.47
    cyclohexanol 679.14
    benzyl alcohol 391.99
    2-ethylhexanol 372.83
    isooctanol 348.55
    dipropyl ether 478.89
    1,2-dichlorobenzene 483.34
    ethyl lactate 310.6
    propylene carbonate 874.19
    n-methylformamide 424.02
    2-pentanol 418.24
    n-pentane 272.16
    1-propoxy-2-propanol 614.71
    1-methoxy-2-propyl acetate 516.01
    2-(2-methoxypropoxy) propanol 400.06
    mesitylene 292.66
    ε-caprolactone 951.85
    p-cymene 257.92
    epichlorohydrin 996.87
    1,1,1-trichloroethane 654.65
    2-aminoethanol 255.17
    morpholine-4-carbaldehyde 966.47
    sulfolane 1871.46
    2,2,4-trimethylpentane 121.72
    2-methyltetrahydrofuran 1089.8
    n-hexyl acetate 718.07
    isooctane 117.4
    2-(2-butoxyethoxy)ethanol 543.37
    sec-butyl acetate 335.31
    tert-butyl acetate 432.73
    decalin 221.29
    glycerin 316.25
    diglyme 681.48
    acrylic acid 354.29
    isopropyl myristate 373.89
    n-butyric acid 537.73
    acetyl acetate 346.47
    di(2-ethylhexyl) phthalate 326.12
    ethyl propionate 386.7
    nitromethane 489.49
    1,2-diethoxyethane 391.18
    benzonitrile 441.51
    trioctyl phosphate 304.71
    1-bromopropane 569.35
    gamma-valerolactone 1431.64
    n-decanol 357.87
    triethyl phosphate 261.85
    4-methyl-2-pentanol 288.76
    propionitrile 310.82
    vinylene carbonate 698.94
    1,1,2-trichlorotrifluoroethane 731.87
    DMS 433.98
    cumene 243.01
    2-octanol 413.77
    2-hexanone 480.04
    octyl acetate 471.37
    limonene 404.62
    1,2-dimethoxyethane 596.92
    ethyl orthosilicate 261.01
    tributyl phosphate 307.07
    diacetone alcohol 494.08
    N,N-dimethylaniline 409.91
    acrylonitrile 330.77
    aniline 474.34
    1,3-propanediol 315.74
    bromobenzene 602.31
    dibromomethane 836.06
    1,1,2,2-tetrachloroethane 1036.15
    2-methyl-cyclohexyl acetate 514.19
    tetrabutyl urea 446.15
    diisobutyl methanol 273.48
    2-phenylethanol 443.93
    styrene 387.57
    dioctyl adipate 453.19
    dimethyl sulfate 460.01
    ethyl butyrate 437.89
    methyl lactate 373.63
    butyl lactate 492.32
    diethyl carbonate 282.77
    propanediol butyl ether 525.57
    triethyl orthoformate 372.09
    p-tert-butyltoluene 283.45
    methyl 4-tert-butylbenzoate 526.07
    morpholine 881.69
    tert-butylamine 397.71
    n-dodecanol 291.06
    dimethoxymethane 622.44
    ethylene carbonate 593.86
    cyrene 564.83
    2-ethoxyethyl acetate 457.29
    2-ethylhexyl acetate 419.36
    1,2,4-trichlorobenzene 618.35
    4-methylpyridine 784.74
    dibutyl ether 469.62
    2,6-dimethyl-4-heptanol 273.48
    DEF 556.58
    dimethyl isosorbide 774.44
    tetrachloroethylene 581.52
    eugenol 500.32
    triacetin 554.2
    span 80 650.13
    1,4-butanediol 179.98
    1,1-dichloroethane 631.36
    2-methyl-1-pentanol 327.69
    methyl formate 345.21
    2-methyl-1-butanol 367.26
    n-decane 216.88
    butyronitrile 355.8
    3,7-dimethyl-1-octanol 375.75
    1-chlorooctane 428.55
    1-chlorotetradecane 222.37
    n-nonane 227.81
    undecane 163.39
    tert-butylcyclohexane 194.02
    cyclooctane 261.12
    cyclopentanol 879.06
    tetrahydropyran 1071.75
    tert-amyl methyl ether 362.17
    2,5,8-trioxanonane 564.31
    1-hexene 459.28
    2-isopropoxyethanol 305.78
    2,2,2-trifluoroethanol 173.34
    methyl butyrate 483.72

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction