1,1,1,2-Tetrachloro-2,2-difluoroethane

Overview IFRA Request a quote

  • Identifiers

    CAS number
    76-11-9

    Molecular formula
    C2Cl4F2

    SMILES
    C(C(Cl)(Cl)Cl)(F)(F)Cl

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 49.88%
    Woody 29.28%
    Sweet 26.41%
    Balsamic 23.32%
    Fishy 21.66%
    Dry 19.36%
    Clean 18.82%
    Animal 17.7%
    Amber 17.06%
    Cooling 16.94%

     

    Flavor
    Odorless 32.48%
    Sulfurous 20.9%
    Bland 19.92%
    Mild 18.38%
    Glue 17.84%
    Bloody 17.8%
    Sweet-like 17.62%
    Sulfury 17.62%
    Bouillon 17.51%
    Skunky 17.42%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    3.4

    pKa est.
    2.59 (strong acid)

    Molecular weight
    203.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • 105 °F (NIOSH, 2024)
    • 41 °C
    • 40.6 °C
    • 105 °F

    Boiling point

    • 197 °F at 760 mmHg (NIOSH, 2024)
    • 92.8 °C
    • 91.5 °C
    • 197 °F

    Flash point

    • 3.07 ˚C est.

    Solubility expt.

    • 0.01 % (NIOSH, 2024)
    • In water, 100 mg/L at 25 °C
    • Soluble in ethanol, ethyl ether, chloroform
    • Solubility in water: none
    • 0.01%

  • Synonyms

    • 1,1-Difluorotetrachloroethane
    • 1,1,1,2-TETRACHLORO-2,2-DIFLUOROETHANE
    • 76-11-9
    • Halocarbon 112a
    • Refrigerant 112a
    • Fluorocarbon 112a
    • CFC 112a
    • Ethane, 1,1,1,2-tetrachloro-2,2-difluoro-
    • Tetrachlorodifluoroethane
    • 1,1,1,2-Tetrachlorodifluoroethane
    • 2,2-Difluoro-1,1,1,2-tetrachloroethane
    • Freon BU
    • R 112a
    • CFC-112a
    • 2,2-Difluorotetrachloroethane
    • F 112a
    • HSDB 1092
    • UNII-76ZK8AK9CJ
    • EINECS 200-934-0
    • BRN 1699461
    • 1,1-Difluoro-1,2,2,2-tetrachloroethane
    • Ethane, 1,1-difluoro-1,2,2,2-tetrachloro-
    • Ethane, 2,2-difluoro-1,1,1,2-tetrachloro-
    • 76ZK8AK9CJ
    • 1,2,2,2-Tetrachloro-1,1-difluoroethane
    • DTXSID90861622
    • 4-01-00-00146 (Beilstein Handbook Reference)
    • R-112A
    • 1,1,1,2-TETRACHLORO-2,2-DIFLUOROETHANE [HSDB]
    • 1,1-Difluoroperchloroethane
    • Ethane, tetrachlorodifluoro-
    • 28605-74-5
    • Freon(R) 112a
    • 1,1Difluoroperchloroethane
    • 2,2Difluorotetrachloroethane
    • FREON 112A
    • SCHEMBL74196
    • 1,1-difluoro-tetrachloroethane
    • tetrachloro-1,1-difluoroethane
    • DTXCID60810521
    • 1,1Difluoro1,2,2,2tetrachloroethane
    • 2,2Difluoro1,1,1,2tetrachloroethane
    • AKOS015853074
    • Ethane, 1,1difluoro1,2,2,2tetrachloro
    • FT102427
    • DB-005607
    • NS00041085
    • 1,1,1,2-TETRACHLORO-2,2-DIFLUOROETANE
    • Q2806545
    • 1,1,1,2-Tetrachloro-2,2-difluoroethane (ACGIH:OSHA)

  • Applications

    1,1,1,2-Tetrachloro-2,2-difluoroethane (CAS 76-11-9) is a highly halogenated ethane used in industry as a specialty solvent and as a chemical intermediate. In practice, it may serve as a cleaning/degreasing solvent for metal surfaces, polymers, and electronics components. It is also used as a precursor for halogenated compounds in fluorinated plastics and resin additives, including flame retardants and stabilizers. It can function as a processing solvent or reaction medium in polymer manufacturing, and as a feedstock for the synthesis of other fluorinated or chlorinated materials. Its use is subject to local regulations and formulation limits, with strict handling and environmental controls.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 225.88
    methanol 328.39
    isopropanol 159.59
    water 44.93
    ethyl acetate 114.98
    n-propanol 152.74
    acetone 266.17
    n-butanol 132.22
    acetonitrile 169.96
    DMF 688.14
    toluene 64.33
    isobutanol 110.85
    1,4-dioxane 192.52
    methyl acetate 125.88
    THF 403.96
    2-butanone 166.89
    n-pentanol 115.09
    sec-butanol 141.84
    n-hexane 52.91
    ethylene glycol 121.29
    NMP 485.43
    cyclohexane 55.53
    DMSO 712.78
    n-butyl acetate 82.02
    n-octanol 90.13
    chloroform 125.21
    n-propyl acetate 110.86
    acetic acid 128.01
    dichloromethane 151.81
    cyclohexanone 161.88
    propylene glycol 84.3
    isopropyl acetate 98.32
    DMAc 492.94
    2-ethoxyethanol 258.97
    isopentanol 107.68
    n-heptane 60.37
    ethyl formate 99.59
    1,2-dichloroethane 124.48
    n-hexanol 100.41
    2-methoxyethanol 371.57
    isobutyl acetate 60.16
    tetrachloromethane 39.75
    n-pentyl acetate 77.4
    transcutol 315.13
    n-heptanol 75.34
    ethylbenzene 55.95
    MIBK 131.03
    2-propoxyethanol 209.62
    tert-butanol 178.25
    MTBE 146.11
    2-butoxyethanol 128.95
    propionic acid 79.28
    o-xylene 73.34
    formic acid 142.05
    diethyl ether 207.94
    m-xylene 70.64
    p-xylene 59.99
    chlorobenzene 34.91
    dimethyl carbonate 101.06
    n-octane 28.99
    formamide 275.71
    cyclopentanone 225.0
    2-pentanone 175.98
    anisole 123.05
    cyclopentyl methyl ether 219.51
    gamma-butyrolactone 199.45
    1-methoxy-2-propanol 300.69
    pyridine 143.32
    3-pentanone 146.97
    furfural 173.3
    n-dodecane 18.17
    diethylene glycol 194.43
    diisopropyl ether 90.95
    tert-amyl alcohol 154.66
    acetylacetone 171.04
    n-hexadecane 19.22
    acetophenone 127.66
    methyl propionate 137.33
    isopentyl acetate 66.47
    trichloroethylene 128.32
    n-nonanol 83.63
    cyclohexanol 118.38
    benzyl alcohol 98.09
    2-ethylhexanol 76.33
    isooctanol 62.92
    dipropyl ether 153.77
    1,2-dichlorobenzene 36.68
    ethyl lactate 89.37
    propylene carbonate 90.63
    n-methylformamide 273.93
    2-pentanol 131.36
    n-pentane 80.24
    1-propoxy-2-propanol 163.08
    1-methoxy-2-propyl acetate 114.91
    2-(2-methoxypropoxy) propanol 134.12
    mesitylene 58.67
    ε-caprolactone 129.27
    p-cymene 57.18
    epichlorohydrin 189.31
    1,1,1-trichloroethane 71.58
    2-aminoethanol 156.35
    morpholine-4-carbaldehyde 372.68
    sulfolane 310.35
    2,2,4-trimethylpentane 28.69
    2-methyltetrahydrofuran 213.61
    n-hexyl acetate 90.43
    isooctane 24.11
    2-(2-butoxyethoxy)ethanol 156.53
    sec-butyl acetate 77.98
    tert-butyl acetate 106.89
    decalin 25.34
    glycerin 128.11
    diglyme 284.79
    acrylic acid 80.7
    isopropyl myristate 57.28
    n-butyric acid 87.56
    acetyl acetate 66.84
    di(2-ethylhexyl) phthalate 45.3
    ethyl propionate 109.99
    nitromethane 255.15
    1,2-diethoxyethane 148.07
    benzonitrile 73.21
    trioctyl phosphate 42.99
    1-bromopropane 117.93
    gamma-valerolactone 240.53
    n-decanol 66.91
    triethyl phosphate 59.12
    4-methyl-2-pentanol 89.01
    propionitrile 121.1
    vinylene carbonate 75.57
    1,1,2-trichlorotrifluoroethane 158.17
    DMS 73.15
    cumene 50.26
    2-octanol 68.05
    2-hexanone 133.17
    octyl acetate 65.04
    limonene 78.8
    1,2-dimethoxyethane 377.5
    ethyl orthosilicate 62.19
    tributyl phosphate 43.87
    diacetone alcohol 156.27
    N,N-dimethylaniline 161.68
    acrylonitrile 133.3
    aniline 89.76
    1,3-propanediol 152.66
    bromobenzene 30.0
    dibromomethane 128.19
    1,1,2,2-tetrachloroethane 125.34
    2-methyl-cyclohexyl acetate 75.06
    tetrabutyl urea 87.66
    diisobutyl methanol 67.94
    2-phenylethanol 82.87
    styrene 57.98
    dioctyl adipate 72.21
    dimethyl sulfate 164.58
    ethyl butyrate 97.56
    methyl lactate 116.69
    butyl lactate 72.28
    diethyl carbonate 60.32
    propanediol butyl ether 110.37
    triethyl orthoformate 80.63
    p-tert-butyltoluene 56.95
    methyl 4-tert-butylbenzoate 113.34
    morpholine 256.04
    tert-butylamine 148.58
    n-dodecanol 54.59
    dimethoxymethane 442.85
    ethylene carbonate 67.61
    cyrene 149.25
    2-ethoxyethyl acetate 86.44
    2-ethylhexyl acetate 57.96
    1,2,4-trichlorobenzene 45.69
    4-methylpyridine 137.55
    dibutyl ether 95.69
    2,6-dimethyl-4-heptanol 67.94
    DEF 265.22
    dimethyl isosorbide 198.6
    tetrachloroethylene 93.39
    eugenol 111.41
    triacetin 90.0
    span 80 97.18
    1,4-butanediol 89.88
    1,1-dichloroethane 97.19
    2-methyl-1-pentanol 91.95
    methyl formate 188.25
    2-methyl-1-butanol 109.3
    n-decane 29.81
    butyronitrile 112.61
    3,7-dimethyl-1-octanol 75.96
    1-chlorooctane 55.91
    1-chlorotetradecane 28.37
    n-nonane 31.24
    undecane 22.48
    tert-butylcyclohexane 24.15
    cyclooctane 33.23
    cyclopentanol 144.49
    tetrahydropyran 172.05
    tert-amyl methyl ether 154.71
    2,5,8-trioxanonane 224.73
    1-hexene 92.93
    2-isopropoxyethanol 170.63
    2,2,2-trifluoroethanol 90.11
    methyl butyrate 133.49

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction