11-Keto-beta-boswellic acid

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  • Identifiers

    CAS number
    17019-92-0

    Molecular formula
    C30H46O4

    SMILES
    C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)O)C)C)[C@@H]2[C@H]1C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 80.75%
    Amber 50.25%
    Cedar 48.71%
    Dry 45.16%
    Spicy 39.2%
    Balsamic 36.15%
    Musk 31.97%
    Vetiver 31.25%
    Sandalwood 30.43%
    Animal 28.93%

     

    Flavor
    Bitter 46.92%
    Woody 43.52%
    Camphor 36.44%
    Pine 31.66%
    Balsam 28.56%
    Herbal 28.52%
    Minty 27.21%
    Cedarleaf 23.76%
    Ripe apricot 23.04%
    Fir needle 22.9%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.2

    pKa est.
    5.54 (weak acid)

    Molecular weight
    470.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    321°C

    Melting point expt.

    • 190 - 191 °C

    Flash point

    • 269.66 ˚C est.

  • Synonyms

    • 11-Keto-beta-boswellic acid
    • 17019-92-0
    • 11-Oxo-beta-boswellic acid
    • Keto-b-boswellic acid
    • 0S3BIF6H0Q
    • DTXSID401313244
    • (4R)-3alpha-hydroxy-11-oxo-urs-12-en-23-oic acid
    • (3alpha,4beta)-3-Hydroxy-11-oxours-12-en-23-oic acid
    • (3R,4R,4AR,6AR,6BS,8AR,11R,12S,12AR,14AR,14BS)-3-HYDROXY-4,6A,6B,8A,11,12,14B-HEPTAMETHYL-14-OXO-1,2,3,4A,5,6,7,8,9,10,11,12,12A,14A-TETRADECAHYDROPICENE-4-CARBOXYLIC ACID
    • RefChem:25877
    • DTXCID001743065
    • 11-Keto Boswellic Acid
    • 11-keto-beta-boswellicacid
    • 11-?Keto-?beta-?boswellic acid
    • 3alpha-Hydroxy-11-oxours-12-en-24-oic acid
    • BETA-BOSWELLIC ACID,11-KETO
    • MFCD06656312
    • CHEMBL437964
    • (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-hydroxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid
    • 11-Keto beta-Boswellic Acid
    • 11-Oxo-.beta.-boswellic acid
    • UNII-0S3BIF6H0Q
    • 11-Keto-.beta.-boswellic acid
    • beta-boswellic acid?
    • 3.alpha.-Hydroxy-11-oxours-12-en-24-oic acid
    • 11-Oxo-b-boswellic acid
    • 11-Keto-b-boswellic acid
    • 11-Keto-ss-boswellic Acid
    • orb1297519
    • SCHEMBL4388405
    • 11-Keto-I(2)-boswellic acid
    • HY-N2056R
    • 11- Keto- beta- boswellic acid
    • HY-N2056
    • BDBM50241261
    • MSK159375
    • AKOS037514519
    • EBC-616761
    • LMPR0106180008
    • MS-28710
    • PD125596
    • 3a-Hydroxy-11-oxo-12-ursen-24-oic acid
    • 11-?Keto-?beta-?boswellic acid (Standard)
    • CS-0018545
    • 11-KETO-.BETA.-BOSWELLIC ACID [DSC]
    • 11-Keto-beta-boswellic acid, analytical standard
    • 11-Keto-beta-boswellic acid11-keto-beta-boswellicacid
    • Q27237166
    • (3|_,4|_)-3-Hydroxy-11-oxours-12-en-23-oic acid
    • 3-Hydroxy-11-oxo-(3alpha,4beta)-Urs-12-en-23-oic acid
    • Urs-12-en-24-oic acid, 3alpha-hydroxy-11-oxo- (8CI)
    • (3.ALPHA.,4.BETA.)-3-HYDROXY-11-OXOURS-12-EN-23-OIC ACID
    • 11-KETO-.BETA.-BOSWELLIC ACID (CONSTITUENT OF BOSWELLIA SERRATA) [DSC]
    • 17019-92-0

  • Applications

    11-Keto-beta-boswellic acid, CAS number: 17019-92-0, is a pentacyclic triterpenoid derived from Boswellia serrata that is primarily studied for anti-inflammatory activity; in pharmaceuticals it is viewed as an active constituent with potential or as part of Boswellia extracts used in dietary supplements, and in cosmetics and personal care it may serve as a natural-extract-derived active ingredient; industrially, it is often considered a marker for quality control of botanical extracts and can function as an intermediate in the synthesis of other boswellic acids.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 21.72
    methanol 17.85
    isopropanol 23.7
    water 0.0
    ethyl acetate 6.34
    n-propanol 30.82
    acetone 13.32
    n-butanol 23.36
    acetonitrile 3.93
    DMF 75.1
    toluene 8.78
    isobutanol 17.99
    1,4-dioxane 37.05
    methyl acetate 7.1
    THF 81.99
    2-butanone 17.23
    n-pentanol 14.11
    sec-butanol 13.91
    n-hexane 0.46
    ethylene glycol 2.1
    NMP 38.02
    cyclohexane 0.61
    DMSO 26.03
    n-butyl acetate 7.16
    n-octanol 4.48
    chloroform 20.63
    n-propyl acetate 5.07
    acetic acid 7.3
    dichloromethane 11.54
    cyclohexanone 23.13
    propylene glycol 6.11
    isopropyl acetate 5.89
    DMAc 40.83
    2-ethoxyethanol 20.36
    isopentanol 12.68
    n-heptane 0.3
    ethyl formate 4.79
    1,2-dichloroethane 9.02
    n-hexanol 14.1
    2-methoxyethanol 36.88
    isobutyl acetate 4.55
    tetrachloromethane 3.09
    n-pentyl acetate 9.82
    transcutol 22.33
    n-heptanol 8.59
    ethylbenzene 3.55
    MIBK 7.81
    2-propoxyethanol 44.98
    tert-butanol 12.94
    MTBE 7.14
    2-butoxyethanol 22.81
    propionic acid 7.03
    o-xylene 4.26
    formic acid 3.29
    diethyl ether 12.1
    m-xylene 5.03
    p-xylene 3.87
    chlorobenzene 6.76
    dimethyl carbonate 6.44
    n-octane 0.14
    formamide 5.38
    cyclopentanone 34.11
    2-pentanone 12.76
    anisole 7.64
    cyclopentyl methyl ether 16.21
    gamma-butyrolactone 23.46
    1-methoxy-2-propanol 38.76
    pyridine 26.48
    3-pentanone 9.84
    furfural 16.77
    n-dodecane 0.06
    diethylene glycol 20.27
    diisopropyl ether 2.2
    tert-amyl alcohol 8.06
    acetylacetone 10.44
    n-hexadecane 0.08
    acetophenone 8.1
    methyl propionate 9.58
    isopentyl acetate 7.8
    trichloroethylene 16.99
    n-nonanol 4.9
    cyclohexanol 10.72
    benzyl alcohol 10.64
    2-ethylhexanol 4.63
    isooctanol 6.01
    dipropyl ether 5.2
    1,2-dichlorobenzene 5.4
    ethyl lactate 4.85
    propylene carbonate 7.94
    n-methylformamide 19.57
    2-pentanol 9.69
    n-pentane 0.6
    1-propoxy-2-propanol 26.38
    1-methoxy-2-propyl acetate 13.77
    2-(2-methoxypropoxy) propanol 12.69
    mesitylene 2.65
    ε-caprolactone 16.54
    p-cymene 2.18
    epichlorohydrin 31.24
    1,1,1-trichloroethane 6.45
    2-aminoethanol 10.41
    morpholine-4-carbaldehyde 46.25
    sulfolane 28.02
    2,2,4-trimethylpentane 0.3
    2-methyltetrahydrofuran 20.34
    n-hexyl acetate 9.7
    isooctane 0.26
    2-(2-butoxyethoxy)ethanol 17.49
    sec-butyl acetate 3.8
    tert-butyl acetate 6.52
    decalin 0.42
    glycerin 8.8
    diglyme 28.0
    acrylic acid 6.17
    isopropyl myristate 2.65
    n-butyric acid 11.15
    acetyl acetate 3.96
    di(2-ethylhexyl) phthalate 5.57
    ethyl propionate 4.67
    nitromethane 10.33
    1,2-diethoxyethane 8.45
    benzonitrile 7.29
    trioctyl phosphate 3.92
    1-bromopropane 6.21
    gamma-valerolactone 49.09
    n-decanol 2.62
    triethyl phosphate 3.21
    4-methyl-2-pentanol 4.99
    propionitrile 8.3
    vinylene carbonate 8.57
    1,1,2-trichlorotrifluoroethane 19.88
    DMS 6.9
    cumene 2.27
    2-octanol 3.96
    2-hexanone 8.62
    octyl acetate 4.16
    limonene 2.6
    1,2-dimethoxyethane 25.47
    ethyl orthosilicate 3.46
    tributyl phosphate 3.11
    diacetone alcohol 11.32
    N,N-dimethylaniline 6.2
    acrylonitrile 9.05
    aniline 11.36
    1,3-propanediol 18.98
    bromobenzene 6.11
    dibromomethane 8.26
    1,1,2,2-tetrachloroethane 15.95
    2-methyl-cyclohexyl acetate 6.16
    tetrabutyl urea 5.52
    diisobutyl methanol 2.48
    2-phenylethanol 13.47
    styrene 3.73
    dioctyl adipate 4.92
    dimethyl sulfate 9.4
    ethyl butyrate 4.64
    methyl lactate 9.18
    butyl lactate 10.51
    diethyl carbonate 2.87
    propanediol butyl ether 16.09
    triethyl orthoformate 5.13
    p-tert-butyltoluene 2.16
    methyl 4-tert-butylbenzoate 11.48
    morpholine 57.98
    tert-butylamine 5.4
    n-dodecanol 1.36
    dimethoxymethane 43.58
    ethylene carbonate 7.29
    cyrene 15.36
    2-ethoxyethyl acetate 14.07
    2-ethylhexyl acetate 6.0
    1,2,4-trichlorobenzene 8.23
    4-methylpyridine 19.25
    dibutyl ether 2.29
    2,6-dimethyl-4-heptanol 2.48
    DEF 14.04
    dimethyl isosorbide 19.96
    tetrachloroethylene 10.96
    eugenol 13.31
    triacetin 7.88
    span 80 11.74
    1,4-butanediol 7.01
    1,1-dichloroethane 7.59
    2-methyl-1-pentanol 7.64
    methyl formate 9.42
    2-methyl-1-butanol 12.31
    n-decane 0.18
    butyronitrile 8.16
    3,7-dimethyl-1-octanol 3.35
    1-chlorooctane 1.36
    1-chlorotetradecane 0.31
    n-nonane 0.15
    undecane 0.1
    tert-butylcyclohexane 0.37
    cyclooctane 0.24
    cyclopentanol 16.34
    tetrahydropyran 28.28
    tert-amyl methyl ether 5.14
    2,5,8-trioxanonane 16.1
    1-hexene 2.17
    2-isopropoxyethanol 12.29
    2,2,2-trifluoroethanol 2.9
    methyl butyrate 6.04

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction