11-Hydroxydodecanoic acid

Overview IFRA Request a quote

  • Identifiers

    CAS number
    32459-66-8

    Molecular formula
    C12H24O3

    SMILES
    CC(CCCCCCCCCC(=O)O)O

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Fragrance
    Fatty 50.18%
    Waxy 39.8%
    Citrus 34.48%
    Oily 34.15%
    Fresh 32.39%
    Milky 31.05%
    Odorless 30.27%
    Creamy 29.28%
    Sweet 28.92%
    Dairy 27.87%

     

    Flavor
    Waxy 57.66%
    Fatty 55.28%
    Green 47.68%
    Oily 41.84%
    Fruity 41.08%
    Cheese 36.02%
    Fat 32.48%
    Soapy 31.63%
    Floral 31.43%
    Creamy 30.57%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.3

    pKa est.
    7.24 (neutral)

    Molecular weight
    216.32 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    332°C

    Flash point

    • 172.48 ˚C est.

  • Synonyms

    • 11-Hydroxydodecanoic acid
    • 32459-66-8
    • DTXSID00954211
    • RefChem:437252
    • DTXCID601382237
    • 977-078-6
    • 11-HYDROXYLAURIC ACID
    • 11-HYDROXY LAURIC ACID
    • Dodecanoic acid, 11-hydroxy-
    • 11-hydroxy-dodecanoic acid
    • Dodecanoic acid,11-hydroxy-
    • SCHEMBL1882126
    • CHEMBL4291425
    • CHEBI:76937
    • LMFA01050165
    • MFCD08063666
    • AKOS027447761
    • DB-291303
    • F77105
    • Q27146452
    • 32459-66-8

  • Applications

    11-Hydroxydodecanoic acid (CAS 32459-66-8) is a hydroxy fatty acid that serves as a versatile building block in multiple industrial segments; as a chemical intermediate it is used to synthesize ester derivatives for polymers and resins, notably in polyester and polyurethane chemistries; in cosmetics and personal care it is evaluated as an emollient or as a precursor for ester-based conditioning agents; in coatings and inks it can act as a reactive starter or plasticizer component to tailor film properties; in detergents and cleaning formulations it may function as a surfactant precursor or as an ester-based surfactant component; in lubrication and industrial formulations it may serve as a lubricant additive or internal plasticizer; and in pharmaceutical manufacturing it can be used as an intermediate for the synthesis of more complex molecules.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 548.53
    methanol 729.28
    isopropanol 382.44
    water 0.18
    ethyl acetate 105.26
    n-propanol 308.16
    acetone 235.69
    n-butanol 280.39
    acetonitrile 46.48
    DMF 406.92
    toluene 25.45
    isobutanol 231.29
    1,4-dioxane 237.88
    methyl acetate 67.22
    THF 833.34
    2-butanone 135.34
    n-pentanol 239.82
    sec-butanol 207.18
    n-hexane 34.69
    ethylene glycol 74.13
    NMP 313.22
    cyclohexane 20.61
    DMSO 1026.5
    n-butyl acetate 173.22
    n-octanol 95.69
    chloroform 105.05
    n-propyl acetate 153.63
    acetic acid 186.19
    dichloromethane 84.02
    cyclohexanone 307.69
    propylene glycol 187.11
    isopropyl acetate 133.07
    DMAc 276.34
    2-ethoxyethanol 365.68
    isopentanol 287.23
    n-heptane 13.78
    ethyl formate 75.07
    1,2-dichloroethane 104.03
    n-hexanol 226.4
    2-methoxyethanol 544.46
    isobutyl acetate 127.22
    tetrachloromethane 23.72
    n-pentyl acetate 116.58
    transcutol 930.78
    n-heptanol 107.61
    ethylbenzene 31.86
    MIBK 182.42
    2-propoxyethanol 369.77
    tert-butanol 519.26
    MTBE 206.56
    2-butoxyethanol 230.46
    propionic acid 151.24
    o-xylene 35.27
    formic acid 89.17
    diethyl ether 124.86
    m-xylene 39.92
    p-xylene 41.08
    chlorobenzene 38.79
    dimethyl carbonate 29.61
    n-octane 6.13
    formamide 107.99
    cyclopentanone 373.15
    2-pentanone 190.37
    anisole 80.66
    cyclopentyl methyl ether 270.93
    gamma-butyrolactone 344.77
    1-methoxy-2-propanol 490.04
    pyridine 102.19
    3-pentanone 83.35
    furfural 229.18
    n-dodecane 4.52
    diethylene glycol 262.58
    diisopropyl ether 57.69
    tert-amyl alcohol 294.02
    acetylacetone 205.44
    n-hexadecane 5.12
    acetophenone 95.62
    methyl propionate 82.01
    isopentyl acetate 178.79
    trichloroethylene 149.17
    n-nonanol 83.98
    cyclohexanol 221.27
    benzyl alcohol 92.09
    2-ethylhexanol 124.69
    isooctanol 93.37
    dipropyl ether 122.52
    1,2-dichlorobenzene 48.77
    ethyl lactate 88.88
    propylene carbonate 174.02
    n-methylformamide 160.55
    2-pentanol 182.6
    n-pentane 13.07
    1-propoxy-2-propanol 293.72
    1-methoxy-2-propyl acetate 188.81
    2-(2-methoxypropoxy) propanol 188.71
    mesitylene 34.79
    ε-caprolactone 253.47
    p-cymene 29.16
    epichlorohydrin 301.89
    1,1,1-trichloroethane 75.12
    2-aminoethanol 249.47
    morpholine-4-carbaldehyde 320.52
    sulfolane 574.88
    2,2,4-trimethylpentane 11.74
    2-methyltetrahydrofuran 376.93
    n-hexyl acetate 154.49
    isooctane 11.45
    2-(2-butoxyethoxy)ethanol 303.42
    sec-butyl acetate 113.78
    tert-butyl acetate 202.17
    decalin 16.8
    glycerin 235.81
    diglyme 470.74
    acrylic acid 94.04
    isopropyl myristate 58.05
    n-butyric acid 293.52
    acetyl acetate 65.06
    di(2-ethylhexyl) phthalate 62.98
    ethyl propionate 101.96
    nitromethane 192.68
    1,2-diethoxyethane 194.96
    benzonitrile 71.28
    trioctyl phosphate 51.74
    1-bromopropane 63.66
    gamma-valerolactone 445.34
    n-decanol 58.6
    triethyl phosphate 59.54
    4-methyl-2-pentanol 135.02
    propionitrile 62.33
    vinylene carbonate 109.38
    1,1,2-trichlorotrifluoroethane 261.8
    DMS 74.23
    cumene 33.13
    2-octanol 70.01
    2-hexanone 190.15
    octyl acetate 72.3
    limonene 50.3
    1,2-dimethoxyethane 457.95
    ethyl orthosilicate 63.88
    tributyl phosphate 63.54
    diacetone alcohol 303.5
    N,N-dimethylaniline 70.18
    acrylonitrile 63.67
    aniline 64.37
    1,3-propanediol 351.78
    bromobenzene 34.79
    dibromomethane 67.91
    1,1,2,2-tetrachloroethane 172.69
    2-methyl-cyclohexyl acetate 118.9
    tetrabutyl urea 83.67
    diisobutyl methanol 71.74
    2-phenylethanol 103.26
    styrene 31.23
    dioctyl adipate 97.0
    dimethyl sulfate 80.99
    ethyl butyrate 117.35
    methyl lactate 98.12
    butyl lactate 127.27
    diethyl carbonate 61.46
    propanediol butyl ether 239.74
    triethyl orthoformate 93.64
    p-tert-butyltoluene 31.76
    methyl 4-tert-butylbenzoate 119.46
    morpholine 435.98
    tert-butylamine 260.1
    n-dodecanol 41.49
    dimethoxymethane 220.56
    ethylene carbonate 102.79
    cyrene 167.92
    2-ethoxyethyl acetate 141.1
    2-ethylhexyl acetate 125.85
    1,2,4-trichlorobenzene 60.78
    4-methylpyridine 104.33
    dibutyl ether 104.97
    2,6-dimethyl-4-heptanol 71.74
    DEF 187.52
    dimethyl isosorbide 286.44
    tetrachloroethylene 119.48
    eugenol 124.56
    triacetin 149.98
    span 80 182.94
    1,4-butanediol 140.4
    1,1-dichloroethane 75.76
    2-methyl-1-pentanol 194.54
    methyl formate 73.89
    2-methyl-1-butanol 207.87
    n-decane 9.12
    butyronitrile 109.71
    3,7-dimethyl-1-octanol 100.8
    1-chlorooctane 42.01
    1-chlorotetradecane 14.62
    n-nonane 8.84
    undecane 6.06
    tert-butylcyclohexane 18.28
    cyclooctane 8.23
    cyclopentanol 286.68
    tetrahydropyran 312.95
    tert-amyl methyl ether 150.62
    2,5,8-trioxanonane 318.83
    1-hexene 106.49
    2-isopropoxyethanol 274.03
    2,2,2-trifluoroethanol 52.25
    methyl butyrate 164.62

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction