10-Hydroxy-2-decenoic acid

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  • Identifiers

    CAS number
    765-01-5

    Molecular formula
    C10H18O3

    SMILES
    C(CCC/C=C/C(=O)O)CCCO

    Safety labels

    Irritant
    Irritant

  • Properties

    XLogP3-AA
    2.2

    Molecular weight
    186.25 g/mol

  • Synonyms

    • 10-Hydroxy-2-decenoic acid
    • 765-01-5
    • 76B519G7TJ
    • DTXSID601045504
    • 10-Hdec
    • RefChem:437035
    • DTXCID301527430
    • 14113-05-4
    • Royal jelly acid
    • (E)-10-hydroxydec-2-enoic acid
    • (E)-10-Hydroxy-2-decenoic acid
    • trans-10-Hydroxy-2-decenoic acid
    • 2-Decenoic acid, 10-hydroxy-, (2E)-
    • 10-Hydroxydecenoic acid
    • MFCD00204506
    • 10-HDA
    • 10-hydroxy-trans-2-decenoic acid
    • 10-hydroxy-2E-decenoic acid
    • (2E)-10-hydroxydec-2-enoic acid
    • CHEMBL5630743
    • NSC-87516
    • 10-Hydroxy-2-decylenic acid
    • Royaljellyacid
    • UNII-76B519G7TJ
    • NSC87516
    • NSC 87516
    • 2-Decenoic acid, 10-hydroxy-, (E)-
    • Queen Bee Acid;(E)-10-Hydroxy-2-decenoic acid
    • SCHEMBL285440
    • 10-HAD
    • orb1304383
    • orb3025110
    • SCHEMBL8040564
    • CHEBI:78668
    • 10-Hydroxy-2(E)-decenoic acid
    • trans-10-hydroxydec-2-enoic acid
    • (E)-10-oxidanyldec-2-enoic acid
    • HY-N1363
    • MSK40115
    • LMFA01050157
    • MSK157411
    • s3827
    • AKOS006282270
    • AKOS025310134
    • (2E)-10-Hydroxy-2-decenoic acid #
    • CCG-266478
    • EBC-153136
    • FH65555
    • FH74146
    • HY-W592871
    • AC-15652
    • AC-34577
    • AS-13924
    • AS-58742
    • SY053098
    • 10-HYDROXY-DEC-(E)-2-ENOIC ACID
    • CS-0016772
    • CS-0648816
    • H1337
    • NS00096511
    • O10366
    • EN300-1704333
    • 113H054
    • A838726
    • F861872
    • Q16908844
    • Z1198152019
    • 10-hydroxy-2E-decenoic acid; (E)-10-hydroxydec-2-enoic acid
    • 14113-05-4

  • Applications

    10-Hydroxy-2-decenoic acid (CAS 765-01-5) is a C10 hydroxy fatty acid derived from royal jelly, primarily used in cosmetics and personal care as a skin-conditioning and moisturizing active ingredient. It is also employed as a chemical intermediate and monomer in the synthesis of biobased polymers and in specialty coatings and adhesives. In pharmaceutical and medicinal chemistry contexts, it is evaluated as a building block for the synthesis of bioactive compounds. The compound has been explored for antimicrobial and anti-inflammatory properties, supporting potential applications in agricultural formulations as a bioactive component for crop protection. In household and cleaning products, it may be incorporated as a fatty-acid derivative contributing to formulation stability and performance, subject to local regulations and formulation limits.

    gpt-5-nano

1 3

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction