1-Phenoxy-2-propanol

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  • Identifiers

    CAS number
    770-35-4

    Molecular formula
    C9H12O2

    SMILES
    CC(COC1=CC=CC=C1)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Floral 63.57%
    Fruity 49.2%
    Sweet 46.17%
    Rose 43.03%
    Balsamic 38.7%
    Fresh 33.15%
    Honey 33.08%
    Vanilla 27.38%
    Hyacinth 26.72%
    Aromatic 26.38%

     

    Flavor
    Sweet 77.73%
    Floral 57.93%
    Fruity 52.94%
    Bitter 38.79%
    Rose 36.56%
    Balsam 34.91%
    Spicy 31.98%
    Honey 31.37%
    Mild 31.22%
    Hyacinth 31.02%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.7

    pKa est.
    7.62 (neutral)

    Molecular weight
    152.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Melting point expt.

    • 11.4 °C

    Boiling point

    • 241.2 °C

    Flash point

    • 110.21 ˚C est.

    Solubility expt.

    • In water, 15.1 g/L at 20 °C

  • Synonyms

    • 1-Phenoxy-2-propanol
    • 770-35-4
    • Propylene phenoxetol
    • 2-Propanol, 1-phenoxy-
    • Propylene glycol phenyl ether
    • 2-Phenoxy-1-methylethanol
    • beta-Phenoxyisopropanol
    • DTXSID9027312
    • 87CZY0NY1A
    • racemic-1-Phenoxy-2-propanol
    • (+-)-1-Phenoxy-2-propanol
    • DTXCID407312
    • RefChem:869821
    • DTXSID30274171
    • 1-Phenoxypropan-2-ol
    • Phenoxyisopropanol
    • 130879-97-9
    • Propylenephenoxythol
    • MFCD00016861
    • (S)-1-Phenoxy-2-Propanol
    • 1-phenoxy-propan-2-ol
    • Phenyl-.beta.-hydroxypropyl ether
    • NSC-24015
    • NCGC00164375-01
    • Propylene phenoxytol
    • 1-Phenoxy-2-propanol 100 microg/mL in Acetonitrile
    • CAS-770-35-4
    • EINECS 212-222-7
    • NSC 24015
    • UNII-87CZY0NY1A
    • AI3-14682
    • HSDB 8185
    • Propylene Glycol 1-Monophenyl Ether
    • 3-phenoxy-2-propanol
    • 2-hydroxy-3-phenoxypropane
    • EC 212-222-7
    • (S)-1-Phenoxypropan-2-ol
    • SCHEMBL50453
    • SCHEMBL124652
    • 1-Phenoxy-2-propanol, tech.
    • SCHEMBL1262500
    • SCHEMBL3267172
    • SCHEMBL6622827
    • SCHEMBL9681057
    • (+/-)-1-phenoxy-2-propanol
    • CHEMBL1327532
    • SCHEMBL27386501
    • 1-Phenoxy-2-propanol, >=93%
    • PHENOXYISOPROPANOL [MART.]
    • 1-PHENOXY-2-HYDROXYPROPANE
    • PHENOXYISOPROPANOL [WHO-DD]
    • NSC24015
    • Tox21_112108
    • Tox21_201710
    • Tox21_303078
    • AKOS000120974
    • AKOS017278201
    • Tox21_112108_1
    • CS-W001255
    • FP71646
    • MSK001832-100M
    • NCGC00164375-02
    • NCGC00164375-03
    • NCGC00256986-01
    • NCGC00259259-01
    • AS-57392
    • SY017804
    • NS00003943
    • P0118
    • ST50824348
    • EN300-20169
    • D77637
    • SBI-0654052.0001
    • 1-Phenoxy-2-propanol, technical, >=80% (GC)
    • F790553
    • Phenoxyisopropanol Solution in Methanol, 100ug/mL
    • SR-01000944764
    • SR-01000944764-1
    • Q20054546
    • 770-35-4

  • Applications

    1-Phenoxy-2-propanol, CAS 770-35-4, is primarily used as a solvent and fragrance ingredient in the cosmetics and perfumery industries, where it can serve to dissolve fragrance components and other actives in formulations. In cosmetics and personal care, it is commonly used as a solvent for active ingredients and fragrances. In household cleaning products, it can act as a solvent or co-solvent for cleaning formulations. In coatings and inks, it serves as a solvent or processing aid in the production of films and printed materials. In adhesives, it can function as a processing solvent and softening agent. In industrial manufacturing, it is often used as an intermediate in chemical syntheses and as a processing aid in various manufacturing processes.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1135.94
    methanol 1394.43
    isopropanol 692.94
    water 8.63
    ethyl acetate 313.08
    n-propanol 667.1
    acetone 536.98
    n-butanol 540.66
    acetonitrile 462.39
    DMF 526.3
    toluene 73.12
    isobutanol 395.44
    1,4-dioxane 754.85
    methyl acetate 378.61
    THF 684.35
    2-butanone 347.82
    n-pentanol 380.43
    sec-butanol 481.62
    n-hexane 37.02
    ethylene glycol 494.61
    NMP 279.88
    cyclohexane 53.73
    DMSO 1167.07
    n-butyl acetate 288.39
    n-octanol 180.63
    chloroform 682.44
    n-propyl acetate 228.14
    acetic acid 883.48
    dichloromethane 690.72
    cyclohexanone 337.55
    propylene glycol 564.08
    isopropyl acetate 139.08
    DMAc 464.65
    2-ethoxyethanol 640.72
    isopentanol 358.8
    n-heptane 45.87
    ethyl formate 280.51
    1,2-dichloroethane 370.26
    n-hexanol 402.62
    2-methoxyethanol 924.76
    isobutyl acetate 150.27
    tetrachloromethane 67.91
    n-pentyl acetate 121.91
    transcutol 1363.34
    n-heptanol 152.69
    ethylbenzene 63.89
    MIBK 140.13
    2-propoxyethanol 519.35
    tert-butanol 694.03
    MTBE 331.56
    2-butoxyethanol 280.06
    propionic acid 495.76
    o-xylene 67.83
    formic acid 342.34
    diethyl ether 352.52
    m-xylene 57.79
    p-xylene 85.46
    chlorobenzene 131.08
    dimethyl carbonate 102.92
    n-octane 16.84
    formamide 389.32
    cyclopentanone 367.13
    2-pentanone 243.26
    anisole 199.21
    cyclopentyl methyl ether 216.42
    gamma-butyrolactone 408.62
    1-methoxy-2-propanol 555.46
    pyridine 328.38
    3-pentanone 168.83
    furfural 406.28
    n-dodecane 18.33
    diethylene glycol 556.09
    diisopropyl ether 71.19
    tert-amyl alcohol 462.17
    acetylacetone 235.85
    n-hexadecane 19.32
    acetophenone 174.24
    methyl propionate 214.71
    isopentyl acetate 225.18
    trichloroethylene 599.51
    n-nonanol 149.57
    cyclohexanol 289.64
    benzyl alcohol 195.44
    2-ethylhexanol 204.67
    isooctanol 117.84
    dipropyl ether 242.11
    1,2-dichlorobenzene 125.26
    ethyl lactate 160.1
    propylene carbonate 261.43
    n-methylformamide 344.49
    2-pentanol 306.17
    n-pentane 35.43
    1-propoxy-2-propanol 369.9
    1-methoxy-2-propyl acetate 224.92
    2-(2-methoxypropoxy) propanol 285.6
    mesitylene 44.38
    ε-caprolactone 290.91
    p-cymene 63.84
    epichlorohydrin 494.88
    1,1,1-trichloroethane 233.96
    2-aminoethanol 634.77
    morpholine-4-carbaldehyde 466.81
    sulfolane 489.5
    2,2,4-trimethylpentane 23.73
    2-methyltetrahydrofuran 390.09
    n-hexyl acetate 197.22
    isooctane 18.03
    2-(2-butoxyethoxy)ethanol 403.24
    sec-butyl acetate 132.11
    tert-butyl acetate 147.91
    decalin 28.3
    glycerin 587.87
    diglyme 669.33
    acrylic acid 382.95
    isopropyl myristate 90.01
    n-butyric acid 513.08
    acetyl acetate 173.25
    di(2-ethylhexyl) phthalate 96.32
    ethyl propionate 163.7
    nitromethane 771.1
    1,2-diethoxyethane 359.53
    benzonitrile 187.3
    trioctyl phosphate 74.59
    1-bromopropane 229.81
    gamma-valerolactone 427.06
    n-decanol 119.18
    triethyl phosphate 102.32
    4-methyl-2-pentanol 149.16
    propionitrile 317.77
    vinylene carbonate 245.65
    1,1,2-trichlorotrifluoroethane 468.88
    DMS 149.8
    cumene 54.76
    2-octanol 93.02
    2-hexanone 236.7
    octyl acetate 118.0
    limonene 100.79
    1,2-dimethoxyethane 754.89
    ethyl orthosilicate 101.38
    tributyl phosphate 95.87
    diacetone alcohol 235.33
    N,N-dimethylaniline 133.32
    acrylonitrile 344.18
    aniline 164.34
    1,3-propanediol 638.31
    bromobenzene 118.53
    dibromomethane 432.86
    1,1,2,2-tetrachloroethane 485.41
    2-methyl-cyclohexyl acetate 153.08
    tetrabutyl urea 121.73
    diisobutyl methanol 110.6
    2-phenylethanol 181.1
    styrene 85.75
    dioctyl adipate 145.9
    dimethyl sulfate 159.92
    ethyl butyrate 203.54
    methyl lactate 176.46
    butyl lactate 140.29
    diethyl carbonate 150.13
    propanediol butyl ether 334.03
    triethyl orthoformate 149.29
    p-tert-butyltoluene 60.78
    methyl 4-tert-butylbenzoate 155.6
    morpholine 743.13
    tert-butylamine 395.33
    n-dodecanol 97.85
    dimethoxymethane 339.44
    ethylene carbonate 207.38
    cyrene 202.59
    2-ethoxyethyl acetate 181.82
    2-ethylhexyl acetate 165.32
    1,2,4-trichlorobenzene 158.6
    4-methylpyridine 243.01
    dibutyl ether 184.22
    2,6-dimethyl-4-heptanol 110.6
    DEF 280.43
    dimethyl isosorbide 295.37
    tetrachloroethylene 319.62
    eugenol 180.34
    triacetin 224.52
    span 80 245.26
    1,4-butanediol 347.11
    1,1-dichloroethane 331.71
    2-methyl-1-pentanol 280.4
    methyl formate 281.41
    2-methyl-1-butanol 338.13
    n-decane 27.3
    butyronitrile 346.21
    3,7-dimethyl-1-octanol 165.41
    1-chlorooctane 94.92
    1-chlorotetradecane 43.51
    n-nonane 26.49
    undecane 21.69
    tert-butylcyclohexane 28.97
    cyclooctane 18.26
    cyclopentanol 314.08
    tetrahydropyran 495.42
    tert-amyl methyl ether 211.38
    2,5,8-trioxanonane 480.21
    1-hexene 141.41
    2-isopropoxyethanol 379.6
    2,2,2-trifluoroethanol 203.19
    methyl butyrate 243.86

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction