1-Naphthaleneacetamide

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  • Identifiers

    CAS number
    86-86-2

    Molecular formula
    C12H11NO

    SMILES
    C1=CC=C2C(=C1)C=CC=C2CC(=O)N

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Floral 60.42%
    Honey 47.47%
    Sweet 44.66%
    Fruity 36.18%
    Grape 35.04%
    Powdery 32.69%
    Rose 29.55%
    Animal 29.12%
    Neroli 28.53%
    Balsamic 28.01%

     

    Flavor
    Sweet 38.11%
    Mild 37.71%
    Honey 37.2%
    Floral 33.43%
    Fruity 32.47%
    Balsam 25.7%
    Odorless 25.53%
    Phenolic 23.7%
    Honeysuckle 23.11%
    Rose 22.94%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.1

    pKa est.
    6.75 (neutral)

    Molecular weight
    185.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    406°C

    Melting point expt.

    • 184 °C

    Flash point

    • 198.89 ˚C est.

    Solubility expt.

    • 0.039 mg/mL at 40 °C

  • Synonyms

    • 1-NAPHTHALENEACETAMIDE
    • 86-86-2
    • 1-Naphthylacetamide
    • 2-(1-Naphthyl)acetamide
    • Naphthaleneacetamide
    • Frufix
    • Amid-Thin
    • 2-(naphthalen-1-yl)acetamide
    • NAAm
    • Dirigol N
    • Amid-Thin W
    • alpha-Naphthylacetamide
    • alpha-NAA amide
    • alpha-Naphthaleneacetamide
    • 1-Naphthylamine, N-acetyl-
    • alpha-Naphthaleneacetic acid amide
    • 11KAX3RJ28
    • DTXSID3020914
    • NSC-34862
    • DTXCID30914
    • CHEBI:81810
    • Naamide
    • RefChem:451192
    • alpha-naphthalene acetamide
    • 201-704-2
    • 1-Naphthalene acetamide
    • 2-naphthalen-1-ylacetamide
    • 1-Naphthyl acetamide
    • 31093-43-3
    • .alpha.-Naphthaleneacetamide
    • MFCD00004047
    • Rosetone
    • .alpha.-Naphthylacetamide
    • Amid kyseliny 1-naftyloctove
    • NSC 34862
    • Naphthalene acetamide
    • 2(1-Naphthyl)acetamide
    • .alpha.-Naphthaleneacetic acid amide
    • (Naphthalen-1-yl)acetamide (1-Naphthylacetamide)
    • Caswell No. 588
    • 1-Naphthyl-acetamide
    • EINECS 201-704-2
    • Amid kyseliny 1-naftyloctove [Czech]
    • 2-(1-Naphthyl)acetamide [BSI:ISO]
    • EPA Pesticide Chemical Code 056001
    • BRN 1945547
    • UNII-11KAX3RJ28
    • AI3-52514
    • Dirigol-N
    • a-Naphthaleneacetamide
    • 2-(1-naphthyl)ethanamide
    • .ALPHA.-NAA AMIDE
    • SCHEMBL66670
    • WLN: L66J B1VZ
    • 4-09-00-02426 (Beilstein Handbook Reference)
    • SCHEMBL1086540
    • SCHEMBL1386762
    • SCHEMBL9678690
    • SCHEMBL9678693
    • 2-(1-Naphthyl)acetamide, ISO
    • CHEMBL3186653
    • SCHEMBL27525101
    • XFNJVKMNNVCYEK-UHFFFAOYSA-
    • MSK24033
    • NSC34862
    • NAPHTHYL)ACETAMIDE, 2-(1-
    • Tox21_200049
    • AKOS003421730
    • AC-5791
    • CS-W023166
    • FS-3193
    • CAS-86-86-2
    • NCGC00164051-01
    • NCGC00164051-02
    • NCGC00257603-01
    • FN140351
    • ST082241
    • SY021125
    • DB-010854
    • N0624
    • NS00006557
    • C18533
    • D70476
    • F079058
    • 1-Naphthyl acetamide 100 microg/mL in Acetonitrile
    • Q4545795
    • 1-Naphthylacetamide, PESTANAL(R), analytical standard
    • 1-Naphthaleneacetamide; (Naphthalen-1-yl)acetamide; 1-Naphthylacetamide
    • InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)
    • 86-86-2

  • Applications

    Chemical name: 1-Naphthaleneacetamide, CAS 86-86-2. 1-Naphthaleneacetamide is used primarily as an organic synthesis intermediate to access a range of naphthalene-based amide derivatives in the field of organic chemistry. In pharmaceutical research, it is commonly employed as a building block for designing naphthylamide-containing compounds and other naphthalene scaffolds for drug development. In dye and pigment chemistry, it may serve as a precursor to naphthyl-based dyes or related intermediates. In polymer science and materials, it provides an aryl-amide scaffold for functionalized polymers and material concepts. In coatings, paints, and inks, it can function as a specialty reagent for formulating advanced material systems. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 57.33
    methanol 193.58
    isopropanol 9.17
    water 0.57
    ethyl acetate 73.96
    n-propanol 32.3
    acetone 251.58
    n-butanol 18.1
    acetonitrile 99.86
    DMF 351.89
    toluene 11.13
    isobutanol 13.17
    1,4-dioxane 280.87
    methyl acetate 84.34
    THF 297.14
    2-butanone 94.05
    n-pentanol 18.91
    sec-butanol 9.1
    n-hexane 0.44
    ethylene glycol 37.49
    NMP 226.97
    cyclohexane 0.3
    DMSO 490.26
    n-butyl acetate 37.94
    n-octanol 9.86
    chloroform 25.15
    n-propyl acetate 41.86
    acetic acid 67.63
    dichloromethane 51.17
    cyclohexanone 110.91
    propylene glycol 19.26
    isopropyl acetate 25.42
    DMAc 193.0
    2-ethoxyethanol 68.45
    isopentanol 15.48
    n-heptane 0.91
    ethyl formate 60.52
    1,2-dichloroethane 56.94
    n-hexanol 26.59
    2-methoxyethanol 163.1
    isobutyl acetate 22.91
    tetrachloromethane 3.05
    n-pentyl acetate 19.98
    transcutol 153.92
    n-heptanol 12.84
    ethylbenzene 8.21
    MIBK 27.52
    2-propoxyethanol 81.02
    tert-butanol 14.91
    MTBE 11.18
    2-butoxyethanol 38.61
    propionic acid 44.8
    o-xylene 7.52
    formic acid 56.77
    diethyl ether 28.51
    m-xylene 8.55
    p-xylene 9.71
    chlorobenzene 17.28
    dimethyl carbonate 49.69
    n-octane 0.44
    formamide 126.39
    cyclopentanone 267.49
    2-pentanone 64.71
    anisole 38.47
    cyclopentyl methyl ether 57.57
    gamma-butyrolactone 309.66
    1-methoxy-2-propanol 62.62
    pyridine 94.68
    3-pentanone 47.45
    furfural 148.29
    n-dodecane 0.49
    diethylene glycol 83.84
    diisopropyl ether 4.58
    tert-amyl alcohol 11.33
    acetylacetone 94.94
    n-hexadecane 0.55
    acetophenone 37.73
    methyl propionate 84.31
    isopentyl acetate 28.43
    trichloroethylene 91.95
    n-nonanol 9.76
    cyclohexanol 13.1
    benzyl alcohol 30.74
    2-ethylhexanol 14.63
    isooctanol 10.82
    dipropyl ether 23.03
    1,2-dichlorobenzene 17.48
    ethyl lactate 25.58
    propylene carbonate 84.75
    n-methylformamide 232.59
    2-pentanol 6.71
    n-pentane 0.21
    1-propoxy-2-propanol 39.38
    1-methoxy-2-propyl acetate 48.69
    2-(2-methoxypropoxy) propanol 34.16
    mesitylene 4.34
    ε-caprolactone 92.53
    p-cymene 7.26
    epichlorohydrin 276.99
    1,1,1-trichloroethane 18.61
    2-aminoethanol 45.31
    morpholine-4-carbaldehyde 219.33
    sulfolane 263.01
    2,2,4-trimethylpentane 0.38
    2-methyltetrahydrofuran 97.73
    n-hexyl acetate 25.39
    isooctane 0.33
    2-(2-butoxyethoxy)ethanol 49.48
    sec-butyl acetate 19.98
    tert-butyl acetate 24.45
    decalin 0.89
    glycerin 46.47
    diglyme 114.77
    acrylic acid 50.3
    isopropyl myristate 10.22
    n-butyric acid 44.44
    acetyl acetate 38.31
    di(2-ethylhexyl) phthalate 14.95
    ethyl propionate 38.11
    nitromethane 289.82
    1,2-diethoxyethane 43.32
    benzonitrile 33.26
    trioctyl phosphate 10.56
    1-bromopropane 11.11
    gamma-valerolactone 289.26
    n-decanol 7.92
    triethyl phosphate 18.55
    4-methyl-2-pentanol 6.87
    propionitrile 46.38
    vinylene carbonate 73.06
    1,1,2-trichlorotrifluoroethane 87.01
    DMS 39.06
    cumene 6.82
    2-octanol 7.15
    2-hexanone 41.56
    octyl acetate 14.38
    limonene 9.01
    1,2-dimethoxyethane 149.21
    ethyl orthosilicate 16.48
    tributyl phosphate 13.01
    diacetone alcohol 41.02
    N,N-dimethylaniline 23.19
    acrylonitrile 81.28
    aniline 24.65
    1,3-propanediol 43.52
    bromobenzene 13.51
    dibromomethane 20.56
    1,1,2,2-tetrachloroethane 51.2
    2-methyl-cyclohexyl acetate 25.68
    tetrabutyl urea 18.9
    diisobutyl methanol 8.04
    2-phenylethanol 30.35
    styrene 9.02
    dioctyl adipate 18.44
    dimethyl sulfate 79.0
    ethyl butyrate 30.3
    methyl lactate 38.88
    butyl lactate 20.78
    diethyl carbonate 24.24
    propanediol butyl ether 30.56
    triethyl orthoformate 20.71
    p-tert-butyltoluene 6.22
    methyl 4-tert-butylbenzoate 32.27
    morpholine 227.8
    tert-butylamine 6.37
    n-dodecanol 6.19
    dimethoxymethane 187.43
    ethylene carbonate 62.13
    cyrene 47.93
    2-ethoxyethyl acetate 38.64
    2-ethylhexyl acetate 22.44
    1,2,4-trichlorobenzene 24.41
    4-methylpyridine 64.46
    dibutyl ether 12.87
    2,6-dimethyl-4-heptanol 8.04
    DEF 74.1
    dimethyl isosorbide 69.65
    tetrachloroethylene 33.12
    eugenol 35.31
    triacetin 33.8
    span 80 26.62
    1,4-butanediol 20.34
    1,1-dichloroethane 21.03
    2-methyl-1-pentanol 15.91
    methyl formate 182.52
    2-methyl-1-butanol 13.78
    n-decane 0.75
    butyronitrile 33.87
    3,7-dimethyl-1-octanol 10.01
    1-chlorooctane 4.53
    1-chlorotetradecane 2.13
    n-nonane 0.61
    undecane 0.6
    tert-butylcyclohexane 1.0
    cyclooctane 0.19
    cyclopentanol 24.96
    tetrahydropyran 80.91
    tert-amyl methyl ether 11.18
    2,5,8-trioxanonane 65.3
    1-hexene 4.13
    2-isopropoxyethanol 39.51
    2,2,2-trifluoroethanol 32.02
    methyl butyrate 51.59

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction