1-Hexacosanol

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  • Identifiers

    CAS number
    506-52-5

    Molecular formula
    C26H54O

    SMILES
    CCCCCCCCCCCCCCCCCCCCCCCCCCO

    Safety labels

  • Odor profile

    Fragrance
    Waxy 80.29%
    Fatty 53.32%
    Oily 44.38%
    Odorless 30.8%
    Clean 19.66%
    Sweet 17.87%
    Fishy 17.77%
    Orris 16.27%
    Balsamic 15.77%
    Creamy 15.42%

     

    Flavor
    Waxy 61.26%
    Alkane 46.08%
    Mild 35.02%
    Fatty 30.17%
    Bland 28.76%
    Wax 25.64%
    Fat 24.96%
    Slightly waxy 24.26%
    Faint 23.14%
    Delicate 22.81%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    12.7

    pKa est.
    8.82 (weak base)

    Molecular weight
    382.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    509°C

    Flash point

    • 225.14 ˚C est.

  • Synonyms

    • 1-Hexacosanol
    • 506-52-5
    • Hexacosan-1-ol
    • CERYL ALCOHOL
    • n-Hexacosanol
    • Hexacosyl alcohol
    • Cerylic alcohol
    • M7SD300NNB
    • DTXSID3027162
    • NSC-4058
    • CHEBI:28415
    • RefChem:25806
    • DTXCID507162
    • 208-044-4
    • Hexacosanol
    • MFCD00002940
    • NSC4058
    • 1-Hexacosanol 10 microg/mL in Methyl-tert-butyl ether
    • UNII-M7SD300NNB
    • Cerylalkohol
    • C26H54O
    • NSC 4058
    • EINECS 208-044-4
    • 1-Hexacosanol (>90%)
    • SCHEMBL15830
    • HEXACOSANOL [USP-RS]
    • orb1296997
    • SCHEMBL1612066
    • SCHEMBL4755732
    • SCHEMBL4755734
    • LMFA05000002
    • AKOS015839859
    • EBC-615927
    • HY-W127493
    • 1-Hexacosanol, >=97% (capillary GC)
    • TS-10157
    • 1-Hexacosanol, synthetic, >=97.0% (GC)
    • CS-0185721
    • H0342
    • NS00019402
    • ST45022110
    • C08381
    • T72543
    • F828253
    • Q4545790
    • HEXACOSANOL (CONSTITUENT OF SAW PALMETTO) [DSC]
    • Hexacosanol, United States Pharmacopeia (USP) Reference Standard
    • 506-52-5

  • Applications

    1-Hexacosanol (CAS 506-52-5) is a long-chain fatty alcohol widely used in cosmetics and personal care as an emollient and conditioning agent, and as a thickener or rheology modifier in certain formulations. It also serves as a nonionic surfactant/emulsifier in household cleaners and other cleaning products. As a waxy component, it is employed in polishes, coatings and related products to improve gloss and slip. In industrial manufacturing and polymers, it can act as a processing aid and lubricating agent to facilitate extrusion or molding, and may serve as a waxy lubricant/anti-blocking additive in plastics and blends. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.82
    methanol 1.95
    isopropanol 2.37
    water 0.01
    ethyl acetate 28.65
    n-propanol 3.5
    acetone 12.34
    n-butanol 5.38
    acetonitrile 3.23
    DMF 21.97
    toluene 10.53
    isobutanol 4.63
    1,4-dioxane 37.78
    methyl acetate 15.36
    THF 136.7
    2-butanone 21.88
    n-pentanol 5.55
    sec-butanol 5.36
    n-hexane 7.35
    ethylene glycol 0.27
    NMP 123.24
    cyclohexane 43.31
    DMSO 45.83
    n-butyl acetate 63.25
    n-octanol 18.01
    chloroform 115.99
    n-propyl acetate 52.44
    acetic acid 7.98
    dichloromethane 101.95
    cyclohexanone 114.4
    propylene glycol 0.98
    isopropyl acetate 41.35
    DMAc 67.95
    2-ethoxyethanol 14.7
    isopentanol 9.74
    n-heptane 20.2
    ethyl formate 11.61
    1,2-dichloroethane 61.54
    n-hexanol 7.79
    2-methoxyethanol 12.5
    isobutyl acetate 44.02
    tetrachloromethane 41.84
    n-pentyl acetate 114.94
    transcutol 176.2
    n-heptanol 15.44
    ethylbenzene 13.39
    MIBK 41.92
    2-propoxyethanol 21.34
    tert-butanol 9.66
    MTBE 28.85
    2-butoxyethanol 42.17
    propionic acid 9.17
    o-xylene 16.11
    formic acid 1.4
    diethyl ether 16.42
    m-xylene 12.26
    p-xylene 20.3
    chlorobenzene 24.93
    dimethyl carbonate 9.59
    n-octane 9.05
    formamide 2.8
    cyclopentanone 112.11
    2-pentanone 28.53
    anisole 29.44
    cyclopentyl methyl ether 85.22
    gamma-butyrolactone 104.0
    1-methoxy-2-propanol 17.43
    pyridine 31.79
    3-pentanone 29.94
    furfural 69.07
    n-dodecane 3.81
    diethylene glycol 6.46
    diisopropyl ether 19.56
    tert-amyl alcohol 16.13
    acetylacetone 48.19
    n-hexadecane 4.79
    acetophenone 45.72
    methyl propionate 22.19
    isopentyl acetate 80.62
    trichloroethylene 118.0
    n-nonanol 21.36
    cyclohexanol 22.84
    benzyl alcohol 11.68
    2-ethylhexanol 19.51
    isooctanol 22.69
    dipropyl ether 72.07
    1,2-dichlorobenzene 45.94
    ethyl lactate 21.37
    propylene carbonate 72.12
    n-methylformamide 6.06
    2-pentanol 6.56
    n-pentane 4.18
    1-propoxy-2-propanol 39.32
    1-methoxy-2-propyl acetate 71.54
    2-(2-methoxypropoxy) propanol 54.86
    mesitylene 15.27
    ε-caprolactone 111.68
    p-cymene 25.7
    epichlorohydrin 96.64
    1,1,1-trichloroethane 100.72
    2-aminoethanol 1.27
    morpholine-4-carbaldehyde 72.69
    sulfolane 255.43
    2,2,4-trimethylpentane 8.52
    2-methyltetrahydrofuran 94.76
    n-hexyl acetate 92.57
    isooctane 5.15
    2-(2-butoxyethoxy)ethanol 61.82
    sec-butyl acetate 53.06
    tert-butyl acetate 91.18
    decalin 16.95
    glycerin 2.62
    diglyme 183.75
    acrylic acid 6.26
    isopropyl myristate 40.27
    n-butyric acid 26.2
    acetyl acetate 27.48
    di(2-ethylhexyl) phthalate 25.9
    ethyl propionate 49.67
    nitromethane 20.03
    1,2-diethoxyethane 90.66
    benzonitrile 16.76
    trioctyl phosphate 21.27
    1-bromopropane 39.14
    gamma-valerolactone 140.24
    n-decanol 13.39
    triethyl phosphate 69.96
    4-methyl-2-pentanol 9.12
    propionitrile 5.84
    vinylene carbonate 44.52
    1,1,2-trichlorotrifluoroethane 74.73
    DMS 38.13
    cumene 14.7
    2-octanol 18.16
    2-hexanone 40.3
    octyl acetate 39.84
    limonene 49.84
    1,2-dimethoxyethane 67.3
    ethyl orthosilicate 74.52
    tributyl phosphate 31.21
    diacetone alcohol 59.52
    N,N-dimethylaniline 30.0
    acrylonitrile 5.26
    aniline 10.42
    1,3-propanediol 3.47
    bromobenzene 35.03
    dibromomethane 69.68
    1,1,2,2-tetrachloroethane 143.19
    2-methyl-cyclohexyl acetate 91.44
    tetrabutyl urea 49.69
    diisobutyl methanol 27.59
    2-phenylethanol 14.84
    styrene 13.4
    dioctyl adipate 68.24
    dimethyl sulfate 35.02
    ethyl butyrate 97.66
    methyl lactate 11.58
    butyl lactate 61.32
    diethyl carbonate 52.36
    propanediol butyl ether 27.76
    triethyl orthoformate 109.3
    p-tert-butyltoluene 25.33
    methyl 4-tert-butylbenzoate 90.68
    morpholine 47.72
    tert-butylamine 8.83
    n-dodecanol 9.56
    dimethoxymethane 21.6
    ethylene carbonate 42.76
    cyrene 55.85
    2-ethoxyethyl acetate 98.76
    2-ethylhexyl acetate 77.17
    1,2,4-trichlorobenzene 57.62
    4-methylpyridine 29.1
    dibutyl ether 81.56
    2,6-dimethyl-4-heptanol 27.59
    DEF 48.87
    dimethyl isosorbide 160.18
    tetrachloroethylene 87.77
    eugenol 55.74
    triacetin 110.12
    span 80 50.29
    1,4-butanediol 1.72
    1,1-dichloroethane 43.66
    2-methyl-1-pentanol 10.1
    methyl formate 5.52
    2-methyl-1-butanol 8.75
    n-decane 10.27
    butyronitrile 8.6
    3,7-dimethyl-1-octanol 26.56
    1-chlorooctane 35.32
    1-chlorotetradecane 10.43
    n-nonane 10.36
    undecane 5.68
    tert-butylcyclohexane 13.16
    cyclooctane 15.19
    cyclopentanol 21.55
    tetrahydropyran 69.03
    tert-amyl methyl ether 39.22
    2,5,8-trioxanonane 103.19
    1-hexene 11.15
    2-isopropoxyethanol 16.74
    2,2,2-trifluoroethanol 6.41
    methyl butyrate 66.89

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction