1-Ethylpiperidine

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  • Identifiers

    CAS number
    766-09-6

    Molecular formula
    C7H15N

    SMILES
    CCN1CCCCC1

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Fishy 81.26%
    Cheesy 67.82%
    Animal 46.59%
    Ripe 45.69%
    Nutty 34.34%
    Roasted 31.07%
    Popcorn 28.83%
    Musty 27.44%
    Oily 22.72%
    Sweet 22.55%

     

    Flavor
    Sweet 41.11%
    Floral 36.64%
    Animal 31.45%
    Bitter 29.41%
    Ammoniacal 27.24%
    Alkaline 26.49%
    Fruity 24.87%
    Spicy 24.16%
    Shrimp 23.38%
    Earthy 23.17%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.0

    pKa est.
    8.74 (weak base)

    Molecular weight
    113.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    131°C

    Flash point

    • 17.99 ˚C est.

  • Synonyms

    • 1-Ethylpiperidine
    • N-ETHYLPIPERIDINE
    • 766-09-6
    • Piperidine, 1-ethyl-
    • N-Aethylpiperidin
    • N-Ethyl piperidine
    • 1-ethyl piperidine
    • 1-ethyl-piperidine
    • NSC 2090
    • 1-Ethylpiperidene
    • EINECS 212-161-6
    • UNII-7IE43L0926
    • CHEBI:39017
    • AI3-22780
    • NSC-2090
    • DTXSID1061102
    • EC 212-161-6
    • 7IE43L0926
    • UN 2386
    • ethylpiperidine
    • N-Aethylpiperidin [German]
    • UN2386
    • 138222-44-3
    • ethyl piperidine
    • EPHP cpd
    • MFCD00006507
    • 1-Ethylpiperidine, 99%
    • SCHEMBL944
    • WLN: T6NTJ A2
    • 966-09-6
    • CHEMBL25053
    • SCHEMBL2703210
    • DTXCID5047900
    • NSC2090
    • AKOS015838625
    • LS-13358
    • DB-056095
    • A9707
    • E0166
    • NS00005670
    • 1-Ethylpiperidine [UN2386] [Flammable liquid]
    • A807350
    • Q22829159

  • Applications

    1-Ethylpiperidine (CAS 766-09-6) is commonly used as an intermediate in the synthesis of pharmaceutical and agrochemical compounds, providing a piperidine scaffold for a range of bioactive molecules. It also acts as a base and nucleophile in various organic transformations. In polymer and coating applications, it can serve as a reactive amine to participate in crosslinking reactions and tailor formulation properties. Additionally, it may be used as a building block for other piperidine-containing intermediates in specialty chemicals. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 806.26
    methanol 723.59
    isopropanol 645.13
    water 1.3
    ethyl acetate 933.16
    n-propanol 849.48
    acetone 757.49
    n-butanol 845.63
    acetonitrile 700.06
    DMF 509.47
    toluene 573.39
    isobutanol 592.91
    1,4-dioxane 1255.18
    methyl acetate 728.89
    THF 1625.32
    2-butanone 853.25
    n-pentanol 481.54
    sec-butanol 685.31
    n-hexane 312.45
    ethylene glycol 143.48
    NMP 794.32
    cyclohexane 567.53
    DMSO 758.86
    n-butyl acetate 1199.5
    n-octanol 262.12
    chloroform 3167.35
    n-propyl acetate 472.2
    acetic acid 816.67
    dichloromethane 2448.38
    cyclohexanone 1222.85
    propylene glycol 235.11
    isopropyl acetate 505.84
    DMAc 433.35
    2-ethoxyethanol 479.02
    isopentanol 599.29
    n-heptane 418.53
    ethyl formate 547.83
    1,2-dichloroethane 1212.11
    n-hexanol 876.07
    2-methoxyethanol 752.04
    isobutyl acetate 292.34
    tetrachloromethane 971.83
    n-pentyl acetate 451.39
    transcutol 1269.57
    n-heptanol 311.46
    ethylbenzene 200.22
    MIBK 345.42
    2-propoxyethanol 960.17
    tert-butanol 650.71
    MTBE 674.02
    2-butoxyethanol 435.54
    propionic acid 723.05
    o-xylene 294.63
    formic acid 176.98
    diethyl ether 1047.36
    m-xylene 292.29
    p-xylene 241.2
    chlorobenzene 809.96
    dimethyl carbonate 147.44
    n-octane 113.57
    formamide 179.42
    cyclopentanone 1192.94
    2-pentanone 637.16
    anisole 307.38
    cyclopentyl methyl ether 911.47
    gamma-butyrolactone 1289.31
    1-methoxy-2-propanol 591.69
    pyridine 1176.44
    3-pentanone 580.43
    furfural 999.79
    n-dodecane 67.01
    diethylene glycol 491.72
    diisopropyl ether 284.25
    tert-amyl alcohol 593.1
    acetylacetone 517.63
    n-hexadecane 74.89
    acetophenone 265.01
    methyl propionate 548.99
    isopentyl acetate 758.84
    trichloroethylene 2040.01
    n-nonanol 232.73
    cyclohexanol 799.06
    benzyl alcohol 289.55
    2-ethylhexanol 579.78
    isooctanol 238.97
    dipropyl ether 892.15
    1,2-dichlorobenzene 639.92
    ethyl lactate 189.33
    propylene carbonate 772.13
    n-methylformamide 388.73
    2-pentanol 568.87
    n-pentane 376.25
    1-propoxy-2-propanol 794.61
    1-methoxy-2-propyl acetate 572.12
    2-(2-methoxypropoxy) propanol 294.91
    mesitylene 185.95
    ε-caprolactone 1026.29
    p-cymene 250.04
    epichlorohydrin 1239.09
    1,1,1-trichloroethane 1574.59
    2-aminoethanol 329.08
    morpholine-4-carbaldehyde 723.58
    sulfolane 1139.78
    2,2,4-trimethylpentane 134.09
    2-methyltetrahydrofuran 1506.82
    n-hexyl acetate 493.46
    isooctane 93.95
    2-(2-butoxyethoxy)ethanol 431.79
    sec-butyl acetate 306.8
    tert-butyl acetate 440.62
    decalin 141.31
    glycerin 253.64
    diglyme 791.01
    acrylic acid 537.3
    isopropyl myristate 202.45
    n-butyric acid 1068.91
    acetyl acetate 550.66
    di(2-ethylhexyl) phthalate 164.67
    ethyl propionate 393.93
    nitromethane 847.6
    1,2-diethoxyethane 796.18
    benzonitrile 512.69
    trioctyl phosphate 130.73
    1-bromopropane 1214.31
    gamma-valerolactone 1109.94
    n-decanol 180.2
    triethyl phosphate 225.96
    4-methyl-2-pentanol 267.02
    propionitrile 844.87
    vinylene carbonate 670.05
    1,1,2-trichlorotrifluoroethane 802.13
    DMS 253.3
    cumene 138.33
    2-octanol 206.86
    2-hexanone 448.8
    octyl acetate 244.66
    limonene 452.27
    1,2-dimethoxyethane 712.69
    ethyl orthosilicate 231.78
    tributyl phosphate 184.82
    diacetone alcohol 368.56
    N,N-dimethylaniline 191.82
    acrylonitrile 728.01
    aniline 640.9
    1,3-propanediol 450.95
    bromobenzene 901.21
    dibromomethane 1873.5
    1,1,2,2-tetrachloroethane 1645.68
    2-methyl-cyclohexyl acetate 381.59
    tetrabutyl urea 199.11
    diisobutyl methanol 282.8
    2-phenylethanol 393.87
    styrene 282.11
    dioctyl adipate 243.06
    dimethyl sulfate 201.75
    ethyl butyrate 697.38
    methyl lactate 213.01
    butyl lactate 305.97
    diethyl carbonate 356.02
    propanediol butyl ether 302.93
    triethyl orthoformate 433.6
    p-tert-butyltoluene 236.2
    methyl 4-tert-butylbenzoate 260.69
    morpholine 1312.39
    tert-butylamine 522.78
    n-dodecanol 147.87
    dimethoxymethane 416.74
    ethylene carbonate 608.47
    cyrene 233.18
    2-ethoxyethyl acetate 471.77
    2-ethylhexyl acetate 658.66
    1,2,4-trichlorobenzene 714.05
    4-methylpyridine 912.88
    dibutyl ether 556.88
    2,6-dimethyl-4-heptanol 282.8
    DEF 638.27
    dimethyl isosorbide 484.74
    tetrachloroethylene 1235.21
    eugenol 240.72
    triacetin 342.85
    span 80 336.72
    1,4-butanediol 173.84
    1,1-dichloroethane 1445.01
    2-methyl-1-pentanol 398.21
    methyl formate 285.77
    2-methyl-1-butanol 622.73
    n-decane 114.42
    butyronitrile 886.92
    3,7-dimethyl-1-octanol 313.66
    1-chlorooctane 292.82
    1-chlorotetradecane 120.65
    n-nonane 130.4
    undecane 84.25
    tert-butylcyclohexane 130.43
    cyclooctane 187.7
    cyclopentanol 809.51
    tetrahydropyran 1588.14
    tert-amyl methyl ether 525.56
    2,5,8-trioxanonane 481.02
    1-hexene 599.45
    2-isopropoxyethanol 344.58
    2,2,2-trifluoroethanol 239.35
    methyl butyrate 508.27

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction