1-Ethoxy-2-propanol

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  • Identifiers

    CAS number
    1569-02-4

    Molecular formula
    C5H12O2

    SMILES
    CCOCC(C)O

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Ethereal 62.3%
    Alcoholic 56.35%
    Sweet 53.92%
    Fruity 49.58%
    Solvent 41.33%
    Fermented 37.62%
    Buttery 34.35%
    Oily 33.21%
    Caramellic 30.81%
    Musty 28.24%

     

    Flavor
    Alcoholic 46.01%
    Sweet 34.62%
    Bitter 33.27%
    Musty 32.76%
    Fruit 32.23%
    Fusel 29.4%
    Vegetable 29.23%
    Oily 28.51%
    Ether 27.84%
    Odorless 27.24%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.2

    pKa est.
    8.26 (weak base)

    Molecular weight
    104.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    129°C

    Flash point

    • 40.94 ˚C est.

  • Synonyms

    • 1-Ethoxy-2-propanol
    • 1569-02-4
    • 1-Ethoxypropan-2-ol
    • 2-PROPANOL, 1-ETHOXY-
    • Propylene glycol monoethyl ether
    • Propylene glycol ethyl ether
    • 1-ethoxy-propan-2-ol
    • ROT9EQO32E
    • DTXSID1041267
    • NSC-2404
    • NSC 2404
    • EINECS 216-374-5
    • UNII-ROT9EQO32E
    • MFCD00067050
    • BRN 1732213
    • NSC2404
    • EC 216-374-5
    • SCHEMBL15671
    • propyleneglycol monoethyl ether
    • DTXCID404283
    • WLN: QY1&1O2
    • CHEMBL3188294
    • 1-Ethoxy-2-propanol, >=95%
    • Tox21_301831
    • AKOS006039439
    • NCGC00255623-01
    • LS-13093
    • CAS-1569-02-4
    • E0446
    • NS00009843
    • EN300-177730
    • Q27288224

  • Applications

    1-Ethoxy-2-propanol (CAS 1569-02-4) is primarily used as a solvent in coatings, sealants, and inks, aiding the dissolution of resins and colorants in formulations. It also serves as a processing solvent and surface-prep aid in adhesive and plastics manufacturing, and is commonly used as an intermediate solvent in the synthesis of polymers and rubber. Additionally, it is employed in industrial cleaning formulations and degreasers, and may act as a co-solvent or intermediate solvent in polymer and plastics processing. These uses cover typical industrial sectors such as coatings and inks, adhesives, cleaning, and polymer processing.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 899.52
    methanol 1575.51
    isopropanol 587.39
    water 67.25
    ethyl acetate 124.88
    n-propanol 637.69
    acetone 269.42
    n-butanol 512.35
    acetonitrile 247.34
    DMF 484.76
    toluene 37.41
    isobutanol 386.01
    1,4-dioxane 356.08
    methyl acetate 175.43
    THF 405.33
    2-butanone 194.41
    n-pentanol 277.75
    sec-butanol 487.32
    n-hexane 38.42
    ethylene glycol 547.94
    NMP 359.5
    cyclohexane 43.12
    DMSO 526.85
    n-butyl acetate 129.95
    n-octanol 147.62
    chloroform 369.7
    n-propyl acetate 84.52
    acetic acid 864.67
    dichloromethane 307.55
    cyclohexanone 255.36
    propylene glycol 548.79
    isopropyl acetate 70.07
    DMAc 356.18
    2-ethoxyethanol 408.09
    isopentanol 282.91
    n-heptane 43.88
    ethyl formate 148.87
    1,2-dichloroethane 152.05
    n-hexanol 330.91
    2-methoxyethanol 805.03
    isobutyl acetate 66.15
    tetrachloromethane 91.4
    n-pentyl acetate 82.1
    transcutol 581.07
    n-heptanol 135.77
    ethylbenzene 27.06
    MIBK 76.93
    2-propoxyethanol 449.54
    tert-butanol 533.81
    MTBE 213.8
    2-butoxyethanol 220.02
    propionic acid 460.13
    o-xylene 40.86
    formic acid 536.2
    diethyl ether 174.32
    m-xylene 35.42
    p-xylene 39.77
    chlorobenzene 73.13
    dimethyl carbonate 44.69
    n-octane 14.14
    formamide 284.82
    cyclopentanone 277.77
    2-pentanone 128.28
    anisole 80.08
    cyclopentyl methyl ether 166.18
    gamma-butyrolactone 287.09
    1-methoxy-2-propanol 457.16
    pyridine 167.57
    3-pentanone 94.95
    furfural 310.46
    n-dodecane 12.55
    diethylene glycol 494.41
    diisopropyl ether 40.73
    tert-amyl alcohol 401.11
    acetylacetone 115.32
    n-hexadecane 13.21
    acetophenone 81.75
    methyl propionate 112.34
    isopentyl acetate 109.78
    trichloroethylene 280.31
    n-nonanol 117.64
    cyclohexanol 295.56
    benzyl alcohol 124.75
    2-ethylhexanol 156.07
    isooctanol 99.1
    dipropyl ether 123.54
    1,2-dichlorobenzene 78.06
    ethyl lactate 95.59
    propylene carbonate 161.64
    n-methylformamide 321.22
    2-pentanol 259.47
    n-pentane 44.14
    1-propoxy-2-propanol 307.96
    1-methoxy-2-propyl acetate 121.92
    2-(2-methoxypropoxy) propanol 184.6
    mesitylene 26.57
    ε-caprolactone 220.42
    p-cymene 41.74
    epichlorohydrin 257.89
    1,1,1-trichloroethane 142.52
    2-aminoethanol 666.2
    morpholine-4-carbaldehyde 389.87
    sulfolane 371.61
    2,2,4-trimethylpentane 26.48
    2-methyltetrahydrofuran 299.88
    n-hexyl acetate 130.78
    isooctane 16.04
    2-(2-butoxyethoxy)ethanol 234.01
    sec-butyl acetate 57.49
    tert-butyl acetate 82.39
    decalin 20.14
    glycerin 651.14
    diglyme 364.39
    acrylic acid 394.86
    isopropyl myristate 53.8
    n-butyric acid 400.11
    acetyl acetate 84.34
    di(2-ethylhexyl) phthalate 70.54
    ethyl propionate 68.64
    nitromethane 448.0
    1,2-diethoxyethane 142.48
    benzonitrile 122.39
    trioctyl phosphate 58.18
    1-bromopropane 125.45
    gamma-valerolactone 341.64
    n-decanol 84.06
    triethyl phosphate 59.92
    4-methyl-2-pentanol 108.86
    propionitrile 205.7
    vinylene carbonate 154.41
    1,1,2-trichlorotrifluoroethane 381.09
    DMS 82.91
    cumene 28.49
    2-octanol 90.84
    2-hexanone 104.24
    octyl acetate 74.51
    limonene 74.95
    1,2-dimethoxyethane 397.67
    ethyl orthosilicate 61.15
    tributyl phosphate 66.83
    diacetone alcohol 159.43
    N,N-dimethylaniline 67.12
    acrylonitrile 233.44
    aniline 116.07
    1,3-propanediol 619.19
    bromobenzene 58.25
    dibromomethane 210.46
    1,1,2,2-tetrachloroethane 261.85
    2-methyl-cyclohexyl acetate 88.32
    tetrabutyl urea 83.32
    diisobutyl methanol 79.34
    2-phenylethanol 118.69
    styrene 36.15
    dioctyl adipate 84.44
    dimethyl sulfate 91.71
    ethyl butyrate 90.47
    methyl lactate 146.35
    butyl lactate 104.26
    diethyl carbonate 62.16
    propanediol butyl ether 253.92
    triethyl orthoformate 80.9
    p-tert-butyltoluene 43.36
    methyl 4-tert-butylbenzoate 103.27
    morpholine 458.55
    tert-butylamine 308.64
    n-dodecanol 64.27
    dimethoxymethane 194.35
    ethylene carbonate 122.04
    cyrene 150.19
    2-ethoxyethyl acetate 98.48
    2-ethylhexyl acetate 86.29
    1,2,4-trichlorobenzene 101.56
    4-methylpyridine 154.02
    dibutyl ether 96.54
    2,6-dimethyl-4-heptanol 79.34
    DEF 187.5
    dimethyl isosorbide 208.4
    tetrachloroethylene 207.24
    eugenol 125.99
    triacetin 138.28
    span 80 184.19
    1,4-butanediol 295.34
    1,1-dichloroethane 174.01
    2-methyl-1-pentanol 194.27
    methyl formate 193.73
    2-methyl-1-butanol 303.88
    n-decane 20.7
    butyronitrile 210.15
    3,7-dimethyl-1-octanol 123.7
    1-chlorooctane 63.68
    1-chlorotetradecane 26.46
    n-nonane 21.82
    undecane 15.25
    tert-butylcyclohexane 24.5
    cyclooctane 15.8
    cyclopentanol 359.9
    tetrahydropyran 303.86
    tert-amyl methyl ether 154.5
    2,5,8-trioxanonane 272.09
    1-hexene 89.07
    2-isopropoxyethanol 243.81
    2,2,2-trifluoroethanol 229.79
    methyl butyrate 109.68

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction