1-Ethoxy-2-methylpropane

Overview IFRA Request a quote

  • Identifiers

    CAS number
    627-02-1

    Molecular formula
    C6H14O

    SMILES
    CCOCC(C)C

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Ethereal 88.06%
    Alcoholic 67.3%
    Fermented 61.28%
    Fruity 52.05%
    Solvent 50.35%
    Sweet 45.18%
    Green 38.49%
    Winey 38.45%
    Cognac 37.91%
    Pungent 36.02%

     

    Flavor
    Fruity 58.62%
    Ether 44.3%
    Green 42.75%
    Sweet 42.49%
    Ethereal 38.5%
    Wine 34.36%
    Alcoholic 32.97%
    Fusel 31.48%
    Fruit 29.49%
    Solvent 27.33%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.8

    pKa est.
    8.14 (weak base)

    Molecular weight
    102.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    80°C

    Flash point

    • -11.99 ˚C est.

  • Synonyms

    • 1-Ethoxy-2-methylpropane
    • 627-02-1
    • DTXSID4074934
    • RefChem:432226
    • DTXCID4043486
    • Ethyl isobutyl ether
    • Isobutyl ethyl ether
    • Ether, ethyl isobutyl
    • Propane, 1-ethoxy-2-methyl-
    • Propane,1-ethoxy-2-methyl-
    • iso-Butyl ethyl ether
    • BRN 1731175
    • (CH3)2CHCH2OC2H5
    • 1-ethoxy-2-methyl-propane
    • SCHEMBL19305
    • SCHEMBL43710
    • 1-Ethoxy-2-methylpropane #
    • SCHEMBL128483
    • SCHEMBL129174
    • SCHEMBL293468
    • SCHEMBL295113
    • SCHEMBL1034500
    • SCHEMBL8728530
    • SCHEMBL8728533
    • SCHEMBL11792073
    • SCHEMBL14150404
    • RQUBQBFVDOLUKC-UHFFFAOYSA-N
    • MFCD00038317
    • AKOS006272327
    • AS-76117
    • DB-080830
    • D93520
    • Q29653286
    • 627-02-1

  • Applications

    1-Ethoxy-2-methylpropane (CAS 627-02-1) is commonly used as an ether solvent in industry, particularly for coatings, inks and adhesives, offering good solubility for resins and polymers; it is also employed as a cleaning and degreasing solvent in industrial formulations; it can serve as a reaction medium or process solvent in organic synthesis and plastics processing, and may act as a co-solvent in polymer and coating formulations to optimize solubility and evaporation characteristics; as an intermediate in chemical synthesis, it enables the preparation of other ethers and related organic products.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1000.81
    methanol 862.3
    isopropanol 889.01
    water 1.7
    ethyl acetate 657.12
    n-propanol 914.65
    acetone 685.53
    n-butanol 1104.75
    acetonitrile 609.94
    DMF 468.21
    toluene 452.9
    isobutanol 788.81
    1,4-dioxane 988.64
    methyl acetate 597.12
    THF 1400.26
    2-butanone 804.87
    n-pentanol 731.71
    sec-butanol 1107.76
    n-hexane 899.6
    ethylene glycol 186.89
    NMP 707.97
    cyclohexane 792.69
    DMSO 523.46
    n-butyl acetate 1304.01
    n-octanol 744.37
    chloroform 2520.85
    n-propyl acetate 568.57
    acetic acid 854.72
    dichloromethane 1724.96
    cyclohexanone 1199.5
    propylene glycol 364.39
    isopropyl acetate 513.27
    DMAc 550.35
    2-ethoxyethanol 642.39
    isopentanol 1016.89
    n-heptane 975.21
    ethyl formate 424.91
    1,2-dichloroethane 855.44
    n-hexanol 1545.99
    2-methoxyethanol 881.15
    isobutyl acetate 452.12
    tetrachloromethane 869.29
    n-pentyl acetate 675.61
    transcutol 1760.92
    n-heptanol 706.74
    ethylbenzene 353.18
    MIBK 460.32
    2-propoxyethanol 1216.92
    tert-butanol 1233.86
    MTBE 1150.39
    2-butoxyethanol 741.17
    propionic acid 703.71
    o-xylene 364.15
    formic acid 184.83
    diethyl ether 975.89
    m-xylene 354.89
    p-xylene 479.66
    chlorobenzene 602.58
    dimethyl carbonate 129.24
    n-octane 286.25
    formamide 142.78
    cyclopentanone 1018.11
    2-pentanone 642.4
    anisole 466.47
    cyclopentyl methyl ether 950.79
    gamma-butyrolactone 887.48
    1-methoxy-2-propanol 725.65
    pyridine 740.44
    3-pentanone 513.6
    furfural 790.83
    n-dodecane 177.12
    diethylene glycol 631.99
    diisopropyl ether 418.6
    tert-amyl alcohol 1278.28
    acetylacetone 485.01
    n-hexadecane 189.7
    acetophenone 414.95
    methyl propionate 411.53
    isopentyl acetate 1121.6
    trichloroethylene 1657.14
    n-nonanol 620.31
    cyclohexanol 1097.69
    benzyl alcohol 403.89
    2-ethylhexanol 1232.05
    isooctanol 605.94
    dipropyl ether 1193.82
    1,2-dichlorobenzene 607.99
    ethyl lactate 274.15
    propylene carbonate 651.35
    n-methylformamide 293.49
    2-pentanol 899.4
    n-pentane 618.87
    1-propoxy-2-propanol 1252.45
    1-methoxy-2-propyl acetate 684.66
    2-(2-methoxypropoxy) propanol 607.88
    mesitylene 278.25
    ε-caprolactone 1011.36
    p-cymene 472.25
    epichlorohydrin 967.25
    1,1,1-trichloroethane 1421.92
    2-aminoethanol 385.3
    morpholine-4-carbaldehyde 710.58
    sulfolane 976.85
    2,2,4-trimethylpentane 323.48
    2-methyltetrahydrofuran 1532.4
    n-hexyl acetate 942.12
    isooctane 236.63
    2-(2-butoxyethoxy)ethanol 779.62
    sec-butyl acetate 456.49
    tert-butyl acetate 575.28
    decalin 352.09
    glycerin 397.42
    diglyme 1202.57
    acrylic acid 495.43
    isopropyl myristate 437.59
    n-butyric acid 1097.56
    acetyl acetate 400.62
    di(2-ethylhexyl) phthalate 336.1
    ethyl propionate 437.33
    nitromethane 652.02
    1,2-diethoxyethane 915.76
    benzonitrile 624.5
    trioctyl phosphate 299.77
    1-bromopropane 1101.09
    gamma-valerolactone 1016.78
    n-decanol 456.24
    triethyl phosphate 349.87
    4-methyl-2-pentanol 515.57
    propionitrile 675.78
    vinylene carbonate 519.88
    1,1,2-trichlorotrifluoroethane 902.32
    DMS 365.38
    cumene 320.15
    2-octanol 556.91
    2-hexanone 701.13
    octyl acetate 496.77
    limonene 816.64
    1,2-dimethoxyethane 1021.45
    ethyl orthosilicate 404.08
    tributyl phosphate 365.57
    diacetone alcohol 604.42
    N,N-dimethylaniline 356.84
    acrylonitrile 611.68
    aniline 472.08
    1,3-propanediol 568.96
    bromobenzene 666.34
    dibromomethane 1548.64
    1,1,2,2-tetrachloroethane 1524.08
    2-methyl-cyclohexyl acetate 710.43
    tetrabutyl urea 388.85
    diisobutyl methanol 640.39
    2-phenylethanol 581.4
    styrene 399.67
    dioctyl adipate 513.37
    dimethyl sulfate 199.67
    ethyl butyrate 816.91
    methyl lactate 257.13
    butyl lactate 520.43
    diethyl carbonate 463.88
    propanediol butyl ether 663.02
    triethyl orthoformate 655.29
    p-tert-butyltoluene 462.4
    methyl 4-tert-butylbenzoate 502.7
    morpholine 1089.62
    tert-butylamine 1060.38
    n-dodecanol 369.02
    dimethoxymethane 364.11
    ethylene carbonate 460.41
    cyrene 384.35
    2-ethoxyethyl acetate 567.23
    2-ethylhexyl acetate 981.52
    1,2,4-trichlorobenzene 704.67
    4-methylpyridine 814.46
    dibutyl ether 998.73
    2,6-dimethyl-4-heptanol 640.39
    DEF 632.74
    dimethyl isosorbide 791.09
    tetrachloroethylene 1125.85
    eugenol 441.42
    triacetin 630.94
    span 80 716.78
    1,4-butanediol 303.64
    1,1-dichloroethane 1231.42
    2-methyl-1-pentanol 752.22
    methyl formate 224.47
    2-methyl-1-butanol 974.4
    n-decane 296.37
    butyronitrile 889.25
    3,7-dimethyl-1-octanol 796.3
    1-chlorooctane 656.04
    1-chlorotetradecane 277.31
    n-nonane 348.1
    undecane 216.5
    tert-butylcyclohexane 408.97
    cyclooctane 331.77
    cyclopentanol 977.14
    tetrahydropyran 1456.63
    tert-amyl methyl ether 929.69
    2,5,8-trioxanonane 777.68
    1-hexene 1239.28
    2-isopropoxyethanol 549.65
    2,2,2-trifluoroethanol 226.14
    methyl butyrate 625.16

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction