1-Ethoxy-1-methoxypropane

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  • Identifiers

    CAS number
    127248-84-4

    Molecular formula
    C6H14O2

    SMILES
    CCC(OC)OCC

  • Odor profile

    Fragrance
    Ethereal 89.58%
    Alcoholic 66.49%
    Fruity 58.68%
    Cognac 58.02%
    Green 57.43%
    Fermented 49.16%
    Brandy 39.93%
    Fresh 38.78%
    Rummy 38.19%
    Pungent 36.92%

     

    Flavor
    Sweet 71.18%
    Green 65.79%
    Ether 51.79%
    Earthy 44.34%
    Vegetable 43.44%
    Alcoholic 40.58%
    Alcohol 40.33%
    Fruit 38.58%
    Ethereal 35.07%
    Fruity 33.36%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    8.12 (weak base)

    Molecular weight
    118.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    106°C

    Flash point

    • 1.18 ˚C est.

  • Synonyms

    • 1-ETHOXY-1-METHOXYPROPANE
    • 127248-84-4
    • DTXSID50601526
    • SCHEMBL441395
    • DTXCID70552283
    • propionaldehyde ethyl methyl acetal
    • propionaldehyde methyl ethyl acetal
    • NS00120623

  • Applications

    1-Ethoxy-1-methoxypropane (CAS 127248-84-4) is a specialty solvent and an intermediate in organic synthesis. It is commonly used as a solvent or reaction medium for a range of synthetic processes and can serve as an intermediate for the preparation of other ethers. It is also employed as a co-solvent in coatings, inks, and adhesives formulations, helping dissolve formulation components in industrial applications. In the polymer and plastics field, the compound may act as a solvent or processing additive in manufacture. Additionally, it may be considered for cleaning formulations and electronics/optical-related processes as a pretreatment or surface-cleaning solvent, subject to local regulations and formulation limits. Compliance with local regulations and formulation limits is essential.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5249.62
    methanol 7065.06
    isopropanol 3856.01
    water 46.78
    ethyl acetate 3042.34
    n-propanol 4123.89
    acetone 3563.35
    n-butanol 3897.25
    acetonitrile 5367.4
    DMF 3101.85
    toluene 1415.33
    isobutanol 3306.39
    1,4-dioxane 4406.54
    methyl acetate 3024.36
    THF 4659.89
    2-butanone 3336.49
    n-pentanol 2831.72
    sec-butanol 4008.69
    n-hexane 1496.02
    ethylene glycol 1262.83
    NMP 2874.04
    cyclohexane 1784.67
    DMSO 3579.37
    n-butyl acetate 2782.84
    n-octanol 1539.03
    chloroform 11037.45
    n-propyl acetate 2231.77
    acetic acid 6460.07
    dichloromethane 10983.16
    cyclohexanone 4017.07
    propylene glycol 1340.3
    isopropyl acetate 1657.29
    DMAc 2605.0
    2-ethoxyethanol 3292.97
    isopentanol 3087.91
    n-heptane 926.7
    ethyl formate 2233.23
    1,2-dichloroethane 4959.13
    n-hexanol 2667.8
    2-methoxyethanol 4396.75
    isobutyl acetate 1238.79
    tetrachloromethane 3476.02
    n-pentyl acetate 1615.91
    transcutol 4556.28
    n-heptanol 1287.46
    ethylbenzene 969.26
    MIBK 1380.95
    2-propoxyethanol 3002.33
    tert-butanol 4267.33
    MTBE 3669.84
    2-butoxyethanol 1745.22
    propionic acid 3398.02
    o-xylene 1028.9
    formic acid 2282.62
    diethyl ether 4081.65
    m-xylene 901.85
    p-xylene 1458.36
    chlorobenzene 2350.55
    dimethyl carbonate 637.6
    n-octane 366.57
    formamide 1995.34
    cyclopentanone 3576.34
    2-pentanone 2495.05
    anisole 1591.24
    cyclopentyl methyl ether 2869.86
    gamma-butyrolactone 3684.92
    1-methoxy-2-propanol 2730.1
    pyridine 3624.81
    3-pentanone 2039.91
    furfural 3331.85
    n-dodecane 233.02
    diethylene glycol 1946.08
    diisopropyl ether 1148.42
    tert-amyl alcohol 4250.28
    acetylacetone 1830.19
    n-hexadecane 253.61
    acetophenone 1402.8
    methyl propionate 1903.17
    isopentyl acetate 2028.41
    trichloroethylene 8103.47
    n-nonanol 1184.07
    cyclohexanol 3531.69
    benzyl alcohol 1527.03
    2-ethylhexanol 1803.47
    isooctanol 1085.62
    dipropyl ether 2139.36
    1,2-dichlorobenzene 2095.7
    ethyl lactate 843.73
    propylene carbonate 2058.48
    n-methylformamide 2406.78
    2-pentanol 2777.38
    n-pentane 1298.69
    1-propoxy-2-propanol 2193.18
    1-methoxy-2-propyl acetate 1382.6
    2-(2-methoxypropoxy) propanol 1090.44
    mesitylene 648.19
    ε-caprolactone 3558.6
    p-cymene 836.23
    epichlorohydrin 4254.44
    1,1,1-trichloroethane 5254.34
    2-aminoethanol 2149.39
    morpholine-4-carbaldehyde 3035.78
    sulfolane 3782.32
    2,2,4-trimethylpentane 658.58
    2-methyltetrahydrofuran 4883.83
    n-hexyl acetate 2148.26
    isooctane 375.72
    2-(2-butoxyethoxy)ethanol 1546.63
    sec-butyl acetate 1363.14
    tert-butyl acetate 1565.3
    decalin 630.31
    glycerin 1629.93
    diglyme 3052.62
    acrylic acid 2801.62
    isopropyl myristate 717.1
    n-butyric acid 4069.01
    acetyl acetate 1773.97
    di(2-ethylhexyl) phthalate 589.46
    ethyl propionate 1643.46
    nitromethane 5292.69
    1,2-diethoxyethane 2406.55
    benzonitrile 2477.19
    trioctyl phosphate 499.83
    1-bromopropane 4236.38
    gamma-valerolactone 3764.08
    n-decanol 781.36
    triethyl phosphate 713.66
    4-methyl-2-pentanol 1351.94
    propionitrile 3770.5
    vinylene carbonate 2150.14
    1,1,2-trichlorotrifluoroethane 3522.77
    DMS 1023.68
    cumene 764.73
    2-octanol 1115.52
    2-hexanone 2137.48
    octyl acetate 905.73
    limonene 1339.93
    1,2-dimethoxyethane 4724.2
    ethyl orthosilicate 760.21
    tributyl phosphate 661.27
    diacetone alcohol 1541.65
    N,N-dimethylaniline 1185.23
    acrylonitrile 3801.42
    aniline 1928.08
    1,3-propanediol 2731.64
    bromobenzene 2545.21
    dibromomethane 7560.61
    1,1,2,2-tetrachloroethane 6275.31
    2-methyl-cyclohexyl acetate 1142.01
    tetrabutyl urea 736.29
    diisobutyl methanol 945.2
    2-phenylethanol 1368.32
    styrene 1229.78
    dioctyl adipate 890.56
    dimethyl sulfate 950.11
    ethyl butyrate 1840.65
    methyl lactate 900.73
    butyl lactate 1051.56
    diethyl carbonate 1092.69
    propanediol butyl ether 1434.57
    triethyl orthoformate 1194.73
    p-tert-butyltoluene 774.16
    methyl 4-tert-butylbenzoate 1077.73
    morpholine 4903.15
    tert-butylamine 3411.01
    n-dodecanol 584.45
    dimethoxymethane 2067.58
    ethylene carbonate 1794.38
    cyrene 978.81
    2-ethoxyethyl acetate 1434.42
    2-ethylhexyl acetate 1692.51
    1,2,4-trichlorobenzene 2349.55
    4-methylpyridine 3582.93
    dibutyl ether 1961.99
    2,6-dimethyl-4-heptanol 945.2
    DEF 2993.94
    dimethyl isosorbide 1559.58
    tetrachloroethylene 5250.88
    eugenol 1044.73
    triacetin 1364.57
    span 80 1129.23
    1,4-butanediol 1534.28
    1,1-dichloroethane 5580.26
    2-methyl-1-pentanol 2478.29
    methyl formate 1807.01
    2-methyl-1-butanol 3440.14
    n-decane 421.54
    butyronitrile 4107.14
    3,7-dimethyl-1-octanol 1423.29
    1-chlorooctane 1221.77
    1-chlorotetradecane 430.94
    n-nonane 491.13
    undecane 293.63
    tert-butylcyclohexane 667.11
    cyclooctane 564.22
    cyclopentanol 3378.03
    tetrahydropyran 5024.16
    tert-amyl methyl ether 2741.26
    2,5,8-trioxanonane 1629.65
    1-hexene 2805.12
    2-isopropoxyethanol 2340.16
    2,2,2-trifluoroethanol 1684.2
    methyl butyrate 2524.57

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction