1-Dodecyl glycidyl ether

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  • Identifiers

    CAS number
    2461-18-9

    Molecular formula
    C15H30O2

    SMILES
    CCCCCCCCCCCCOCC1CO1

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Waxy 52.0%
    Fatty 48.44%
    Fruity 48.34%
    Oily 47.09%
    Fresh 36.74%
    Floral 35.43%
    Citrus 35.17%
    Sweet 29.77%
    Clean 28.96%
    Rose 23.78%

     

    Flavor
    Waxy 53.83%
    Fatty 47.91%
    Oily 39.46%
    Floral 34.33%
    Mild 32.57%
    Mushroom 32.17%
    Fat 30.39%
    Coconut 29.07%
    Creamy 27.68%
    Flower 27.04%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    5.4

    pKa est.
    5.5 (weak acid)

    Molecular weight
    242.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    311°C

    Flash point

    • 124.76 ˚C est.

    Solubility expt.

    • less than 1 mg/mL at 66 °F (NTP, 1992)

  • Synonyms

    • 1-Dodecyl glycidyl ether
    • C12Ge cpd
    • RefChem:590303
    • 2461-18-9
    • Lauryl glycidyl ether
    • DODECYL GLYCIDYL ETHER
    • Glycidyl Lauryl Ether
    • 2-(dodecoxymethyl)oxirane
    • 2-[(Dodecyloxy)methyl]oxirane
    • laurylglycidylether
    • N-Dodecyl glycidyl ether
    • Oxirane, 2-[(dodecyloxy)methyl]-
    • Ether, dodecyl 2,3-epoxypropyl
    • ((Dodecyloxy)methyl)oxirane
    • Propane, 1-(dodecyloxy)-2,3-epoxy-
    • Oxirane, ((dodecyloxy)methyl)-
    • [(Dodecyloxy)methyl]oxirane
    • MFCD00022344
    • 2-((Dodecyloxy)methyl)oxirane
    • DTXSID0025494
    • Oxirane, [(dodecyloxy)methyl]-
    • Oxirane, 2-((dodecyloxy)methyl)-
    • 84653J97E3
    • dodecylglycidyl ether
    • CCRIS 2635
    • HSDB 5462
    • EINECS 219-554-1
    • UNII-84653J97E3
    • glycidyl dodecyl ether
    • DSSTox_CID_5494
    • DENACOL EX 192
    • DSSTox_RID_78656
    • DSSTox_GSID_28774
    • SCHEMBL15970
    • DTXCID605494
    • SCHEMBL6036747
    • SCHEMBL7152967
    • GLYCIDYL N-DODECYL ETHER
    • 2-[(dodecyloxy)methyl]-Oxirane
    • CHEMBL1574716
    • 2-[(Dodecyloxy)methyl]oxirane #
    • DTXSID301370281
    • Tox21_200787
    • Tox21_303452
    • [(DODECYLOXY)METHYL] OXIRANE
    • MSK170119
    • STL453740
    • DODECYL ALCOHOL GLYCIDYL ETHER
    • AKOS024332807
    • DODECYL 2,3-EPOXYPROPYL ETHER
    • 1-DODECYL GLYCIDYL ETHER [HSDB]
    • NCGC00091870-01
    • NCGC00091870-02
    • NCGC00257384-01
    • NCGC00258341-01
    • 1,2-EPOXY-3-(DODECYLOXY)PROPANE
    • AS-60945
    • SY056407
    • CAS-2461-18-9
    • CAS-68609-97-2
    • CS-0320613
    • G0448
    • NS00020611
    • T72150
    • Q27269499
    • 122608-93-9
    • 2461-18-9

  • Applications

    1-Dodecyl glycidyl ether (CAS 2461-18-9) is primarily used as a reactive diluent for epoxy resin systems, reducing formulation viscosity while becoming covalently incorporated during cure. It also serves as a flexibilizing modifier in epoxy-based coatings and adhesives, improving film flexibility and impact resistance. As an intermediate, it is used in the synthesis of specialty epoxy resins and related polymers, enabling tailored performance. In electronics-related coatings and encapsulation, it may form part of potting and protective epoxy formulations. Additionally, it can act as a precursor to surface-active or surfactant-like materials derived from fatty-chain glycidyl ethers, expanding options for formulated cleaners and coatings.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 618.12
    methanol 366.9
    isopropanol 622.32
    water 0.02
    ethyl acetate 1829.34
    n-propanol 629.12
    acetone 1295.26
    n-butanol 735.26
    acetonitrile 662.59
    DMF 470.48
    toluene 563.28
    isobutanol 509.02
    1,4-dioxane 1919.93
    methyl acetate 924.38
    THF 3116.2
    2-butanone 1161.94
    n-pentanol 513.83
    sec-butanol 630.45
    n-hexane 294.13
    ethylene glycol 41.83
    NMP 640.12
    cyclohexane 1110.45
    DMSO 1155.96
    n-butyl acetate 1564.24
    n-octanol 235.12
    chloroform 3802.42
    n-propyl acetate 1538.83
    acetic acid 598.24
    dichloromethane 3879.41
    cyclohexanone 2424.0
    propylene glycol 105.66
    isopropyl acetate 1367.09
    DMAc 585.64
    2-ethoxyethanol 795.93
    isopentanol 741.82
    n-heptane 340.83
    ethyl formate 581.46
    1,2-dichloroethane 2654.37
    n-hexanol 540.4
    2-methoxyethanol 817.35
    isobutyl acetate 902.84
    tetrachloromethane 731.94
    n-pentyl acetate 912.07
    transcutol 2691.2
    n-heptanol 259.17
    ethylbenzene 358.6
    MIBK 973.03
    2-propoxyethanol 864.68
    tert-butanol 840.24
    MTBE 1293.44
    2-butoxyethanol 570.21
    propionic acid 481.04
    o-xylene 372.2
    formic acid 75.93
    diethyl ether 1685.56
    m-xylene 374.98
    p-xylene 447.54
    chlorobenzene 853.39
    dimethyl carbonate 201.15
    n-octane 91.59
    formamide 152.1
    cyclopentanone 1892.03
    2-pentanone 1416.22
    anisole 668.48
    cyclopentyl methyl ether 1619.27
    gamma-butyrolactone 1631.08
    1-methoxy-2-propanol 840.87
    pyridine 1483.04
    3-pentanone 959.95
    furfural 1106.45
    n-dodecane 40.73
    diethylene glycol 346.7
    diisopropyl ether 630.11
    tert-amyl alcohol 683.52
    acetylacetone 1421.67
    n-hexadecane 49.81
    acetophenone 659.44
    methyl propionate 843.33
    isopentyl acetate 1262.02
    trichloroethylene 3585.95
    n-nonanol 229.49
    cyclohexanol 998.44
    benzyl alcohol 429.54
    2-ethylhexanol 498.85
    isooctanol 277.57
    dipropyl ether 1431.38
    1,2-dichlorobenzene 836.56
    ethyl lactate 380.07
    propylene carbonate 976.75
    n-methylformamide 271.1
    2-pentanol 631.78
    n-pentane 253.8
    1-propoxy-2-propanol 914.3
    1-methoxy-2-propyl acetate 1089.89
    2-(2-methoxypropoxy) propanol 422.04
    mesitylene 293.24
    ε-caprolactone 1845.56
    p-cymene 307.42
    epichlorohydrin 2512.58
    1,1,1-trichloroethane 2389.13
    2-aminoethanol 152.27
    morpholine-4-carbaldehyde 869.33
    sulfolane 1593.46
    2,2,4-trimethylpentane 113.51
    2-methyltetrahydrofuran 2306.07
    n-hexyl acetate 831.72
    isooctane 105.24
    2-(2-butoxyethoxy)ethanol 657.91
    sec-butyl acetate 1055.69
    tert-butyl acetate 1304.82
    decalin 225.7
    glycerin 130.45
    diglyme 1666.25
    acrylic acid 287.49
    isopropyl myristate 319.15
    n-butyric acid 1190.15
    acetyl acetate 999.69
    di(2-ethylhexyl) phthalate 189.0
    ethyl propionate 1177.83
    nitromethane 1065.69
    1,2-diethoxyethane 1638.9
    benzonitrile 631.21
    trioctyl phosphate 161.45
    1-bromopropane 1925.59
    gamma-valerolactone 2112.91
    n-decanol 154.14
    triethyl phosphate 441.2
    4-methyl-2-pentanol 406.89
    propionitrile 691.26
    vinylene carbonate 714.65
    1,1,2-trichlorotrifluoroethane 1249.77
    DMS 484.08
    cumene 249.56
    2-octanol 197.96
    2-hexanone 1123.99
    octyl acetate 336.85
    limonene 568.49
    1,2-dimethoxyethane 1779.64
    ethyl orthosilicate 448.27
    tributyl phosphate 240.25
    diacetone alcohol 891.86
    N,N-dimethylaniline 373.46
    acrylonitrile 585.4
    aniline 480.28
    1,3-propanediol 352.97
    bromobenzene 1066.97
    dibromomethane 2807.59
    1,1,2,2-tetrachloroethane 3143.91
    2-methyl-cyclohexyl acetate 765.92
    tetrabutyl urea 289.76
    diisobutyl methanol 378.86
    2-phenylethanol 435.59
    styrene 458.05
    dioctyl adipate 439.22
    dimethyl sulfate 308.88
    ethyl butyrate 1382.65
    methyl lactate 234.44
    butyl lactate 474.07
    diethyl carbonate 736.3
    propanediol butyl ether 373.08
    triethyl orthoformate 895.49
    p-tert-butyltoluene 278.18
    methyl 4-tert-butylbenzoate 458.75
    morpholine 2268.28
    tert-butylamine 630.71
    n-dodecanol 117.38
    dimethoxymethane 690.85
    ethylene carbonate 788.24
    cyrene 381.95
    2-ethoxyethyl acetate 1020.18
    2-ethylhexyl acetate 1033.2
    1,2,4-trichlorobenzene 909.51
    4-methylpyridine 1101.95
    dibutyl ether 832.6
    2,6-dimethyl-4-heptanol 378.86
    DEF 1145.75
    dimethyl isosorbide 828.95
    tetrachloroethylene 2010.27
    eugenol 352.18
    triacetin 745.18
    span 80 409.32
    1,4-butanediol 143.53
    1,1-dichloroethane 2413.25
    2-methyl-1-pentanol 492.07
    methyl formate 206.59
    2-methyl-1-butanol 591.32
    n-decane 93.63
    butyronitrile 922.67
    3,7-dimethyl-1-octanol 344.5
    1-chlorooctane 334.36
    1-chlorotetradecane 112.02
    n-nonane 99.67
    undecane 56.66
    tert-butylcyclohexane 167.57
    cyclooctane 264.97
    cyclopentanol 822.11
    tetrahydropyran 3149.34
    tert-amyl methyl ether 874.29
    2,5,8-trioxanonane 819.62
    1-hexene 704.68
    2-isopropoxyethanol 670.8
    2,2,2-trifluoroethanol 176.67
    methyl butyrate 1531.59

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction