1-Decanethiol

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  • Identifiers

    CAS number
    143-10-2

    Molecular formula
    C10H22S

    SMILES
    CCCCCCCCCCS

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Sulfurous 87.03%
    Meaty 79.58%
    Fatty 73.81%
    Savory 58.1%
    Roasted 57.13%
    Vegetable 52.92%
    Onion 40.67%
    Alliaceous 40.17%
    Burnt 39.67%
    Mushroom 36.93%

     

    Flavor
    Fatty 45.32%
    Waxy 34.34%
    Fat 31.67%
    Meaty 31.51%
    Sulfurous 30.82%
    Burnt 27.48%
    Alkane 27.17%
    Fishy 26.93%
    Sulfury 26.54%
    Skunky 25.53%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    5.5

    pKa est.
    9.14 (weak base)

    Molecular weight
    174.35 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Melting point expt.

    • -15 °F (NIOSH, 2024)
    • -26 °C
    • -15 °F

    Boiling point

    • 465 °F at 760 mmHg (NIOSH, 2024)
    • 241 °C
    • 465 °F

    Flash point

    • 88.85 ˚C est.
    • 209 °F (NIOSH, 2024)
    • 98 °C
    • 209 °F

    Solubility expt.

    • Insoluble (NIOSH, 2024)
    • Solubility in water: none
    • Insoluble

  • Synonyms

    • 1-DECANETHIOL
    • 143-10-2
    • decane-1-thiol
    • Decyl mercaptan
    • 1-Mercaptodecane
    • Decylmercaptan
    • decanethiol
    • n-decanethiol
    • 1-decylthiol
    • A2H8YRB236
    • AI3-06520
    • NSC 850
    • EINECS 205-584-2
    • DTXSID7059727
    • NSC-850
    • n-decylmercaptan
    • Decanethiol-(1)
    • N-decatyl mercaptan
    • decanthiol
    • nDecylmercaptan
    • 1Mercaptodecane
    • n-decanthiol
    • n-Decyl mercaptan
    • n-decane-1-thiol
    • D1T
    • tert-Decyl mercaptan
    • MFCD00004884
    • 1-DECANTHIOL
    • 1-Decanethiol, 96%
    • 1-Decanethiol, 99%
    • UNII-A2H8YRB236
    • SCHEMBL93416
    • NSC850
    • DTXCID4034659
    • AKOS015897633
    • DB07611
    • LS-13918
    • 1-Decanethiol, technical, >=95% (GC)
    • DB-021361
    • D0016
    • NS00024654
    • D94658
    • EN300-1288842
    • Q27096831

  • Applications

    1-Decanethiol, CAS 143-10-2, is a mercaptan with a distinctive odor and is primarily used as a fragrance ingredient in perfumery and cosmetics at very low concentrations. In the cosmetics and personal care sectors, it serves as an odorant contributing to fragrance character. In the chemical manufacturing industry, it is commonly used as an organic intermediate to synthesize thioethers and disulfides, or as a precursor for thiol-related transformations. In polymers and coatings, 1-Decanethiol can function as a chain transfer agent in radical polymerizations or participate in thiol-ene click chemistry to form networks and surface coatings. In surface science and electronics, it is used to form self-assembled monolayers on metal surfaces (e.g., gold) for surface modification in sensors and electronic applications. Note: use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1315.3
    methanol 608.29
    isopropanol 1726.52
    water 0.01
    ethyl acetate 2678.73
    n-propanol 1531.65
    acetone 3770.79
    n-butanol 2118.85
    acetonitrile 965.82
    DMF 1362.91
    toluene 1753.7
    isobutanol 1395.81
    1,4-dioxane 4570.46
    methyl acetate 1499.8
    THF 9764.71
    2-butanone 3219.57
    n-pentanol 1475.95
    sec-butanol 1923.39
    n-hexane 3309.26
    ethylene glycol 58.82
    NMP 1300.79
    cyclohexane 5771.98
    DMSO 2623.64
    n-butyl acetate 5942.1
    n-octanol 933.79
    chloroform 4228.55
    n-propyl acetate 2516.38
    acetic acid 619.83
    dichloromethane 3921.73
    cyclohexanone 5307.58
    propylene glycol 166.94
    isopropyl acetate 2108.54
    DMAc 996.24
    2-ethoxyethanol 1092.52
    isopentanol 2012.24
    n-heptane 4564.03
    ethyl formate 803.69
    1,2-dichloroethane 3524.61
    n-hexanol 2946.17
    2-methoxyethanol 1435.69
    isobutyl acetate 1614.35
    tetrachloromethane 1199.24
    n-pentyl acetate 1987.99
    transcutol 4432.09
    n-heptanol 1057.6
    ethylbenzene 930.24
    MIBK 2156.09
    2-propoxyethanol 2305.91
    tert-butanol 2895.99
    MTBE 4480.19
    2-butoxyethanol 1206.7
    propionic acid 628.82
    o-xylene 853.96
    formic acid 38.26
    diethyl ether 6443.5
    m-xylene 969.96
    p-xylene 1157.06
    chlorobenzene 1487.31
    dimethyl carbonate 269.37
    n-octane 840.56
    formamide 80.41
    cyclopentanone 4248.88
    2-pentanone 3736.97
    anisole 1141.49
    cyclopentyl methyl ether 4889.64
    gamma-butyrolactone 2463.54
    1-methoxy-2-propanol 1470.81
    pyridine 3232.22
    3-pentanone 2311.93
    furfural 1424.18
    n-dodecane 272.38
    diethylene glycol 640.78
    diisopropyl ether 2213.06
    tert-amyl alcohol 2118.46
    acetylacetone 2152.16
    n-hexadecane 337.21
    acetophenone 908.21
    methyl propionate 1238.71
    isopentyl acetate 3790.52
    trichloroethylene 3927.3
    n-nonanol 862.21
    cyclohexanol 2568.92
    benzyl alcohol 638.31
    2-ethylhexanol 2573.24
    isooctanol 978.09
    dipropyl ether 8547.7
    1,2-dichlorobenzene 1096.12
    ethyl lactate 378.12
    propylene carbonate 1307.72
    n-methylformamide 375.87
    2-pentanol 2014.23
    n-pentane 2277.12
    1-propoxy-2-propanol 2809.6
    1-methoxy-2-propyl acetate 2026.73
    2-(2-methoxypropoxy) propanol 732.49
    mesitylene 728.9
    ε-caprolactone 2982.44
    p-cymene 967.83
    epichlorohydrin 3196.14
    1,1,1-trichloroethane 3720.29
    2-aminoethanol 213.64
    morpholine-4-carbaldehyde 1454.38
    sulfolane 2620.73
    2,2,4-trimethylpentane 534.25
    2-methyltetrahydrofuran 7344.92
    n-hexyl acetate 1978.69
    isooctane 521.93
    2-(2-butoxyethoxy)ethanol 1241.22
    sec-butyl acetate 1696.79
    tert-butyl acetate 2362.45
    decalin 954.07
    glycerin 187.99
    diglyme 2841.1
    acrylic acid 335.91
    isopropyl myristate 818.13
    n-butyric acid 1823.05
    acetyl acetate 1130.4
    di(2-ethylhexyl) phthalate 376.34
    ethyl propionate 1592.41
    nitromethane 921.72
    1,2-diethoxyethane 4714.61
    benzonitrile 1045.25
    trioctyl phosphate 393.13
    1-bromopropane 4982.11
    gamma-valerolactone 3090.41
    n-decanol 600.75
    triethyl phosphate 755.02
    4-methyl-2-pentanol 1081.99
    propionitrile 1380.05
    vinylene carbonate 812.92
    1,1,2-trichlorotrifluoroethane 1341.85
    DMS 678.94
    cumene 579.62
    2-octanol 816.44
    2-hexanone 3378.61
    octyl acetate 837.39
    limonene 2307.73
    1,2-dimethoxyethane 3596.93
    ethyl orthosilicate 887.79
    tributyl phosphate 530.81
    diacetone alcohol 1513.33
    N,N-dimethylaniline 708.4
    acrylonitrile 931.94
    aniline 1090.17
    1,3-propanediol 530.32
    bromobenzene 1901.39
    dibromomethane 3928.57
    1,1,2,2-tetrachloroethane 3773.97
    2-methyl-cyclohexyl acetate 1561.5
    tetrabutyl urea 709.66
    diisobutyl methanol 1611.73
    2-phenylethanol 972.23
    styrene 1244.14
    dioctyl adipate 869.08
    dimethyl sulfate 401.89
    ethyl butyrate 3522.67
    methyl lactate 278.48
    butyl lactate 816.97
    diethyl carbonate 1344.98
    propanediol butyl ether 672.15
    triethyl orthoformate 2103.19
    p-tert-butyltoluene 921.88
    methyl 4-tert-butylbenzoate 683.91
    morpholine 5105.81
    tert-butylamine 2578.89
    n-dodecanol 462.4
    dimethoxymethane 1594.76
    ethylene carbonate 969.55
    cyrene 528.61
    2-ethoxyethyl acetate 1545.32
    2-ethylhexyl acetate 3349.52
    1,2,4-trichlorobenzene 1163.55
    4-methylpyridine 2684.91
    dibutyl ether 4097.19
    2,6-dimethyl-4-heptanol 1611.73
    DEF 2251.89
    dimethyl isosorbide 1397.86
    tetrachloroethylene 2373.1
    eugenol 531.2
    triacetin 948.14
    span 80 906.16
    1,4-butanediol 195.25
    1,1-dichloroethane 3822.55
    2-methyl-1-pentanol 1328.3
    methyl formate 288.94
    2-methyl-1-butanol 1611.94
    n-decane 667.56
    butyronitrile 2423.51
    3,7-dimethyl-1-octanol 1179.87
    1-chlorooctane 1426.34
    1-chlorotetradecane 434.47
    n-nonane 842.25
    undecane 396.76
    tert-butylcyclohexane 772.09
    cyclooctane 1600.34
    cyclopentanol 2086.58
    tetrahydropyran 10712.49
    tert-amyl methyl ether 2654.01
    2,5,8-trioxanonane 1424.18
    1-hexene 5302.42
    2-isopropoxyethanol 1040.37
    2,2,2-trifluoroethanol 114.93
    methyl butyrate 2258.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction