1-Chloro-1,1-difluoroethane

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  • Identifiers

    CAS number
    75-68-3

    Molecular formula
    C2H3ClF2

    SMILES
    CC(F)(F)Cl

    Safety labels

    Flammable
    Flammable

    Compressed Gas
    Compressed Gas

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Floral 36.0%
    Odorless 34.28%
    Sweet 30.84%
    Woody 27.02%
    Fresh 24.76%
    Citrus 24.48%
    Fishy 23.5%
    Balsamic 20.35%
    Grapefruit 20.21%
    Clean 19.36%

     

    Flavor
    Sulfurous 30.74%
    Meaty 27.96%
    Odorless 27.16%
    Sulfury 25.88%
    Fishy 21.63%
    Onion 20.55%
    Glue 19.23%
    Bloody 19.19%
    Bouillon 18.44%
    Skunky 18.41%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.0

    pKa est.
    7.47 (neutral)

    Molecular weight
    100.49 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -130.8 °C
    • -131 °C

    Boiling point

    • -9.1 °C
    • -9 °C

    Flash point

    • -49.63 ˚C est.
    • Flammable gas

    Solubility expt.

    • Insoluble in water; sol in benzene
    • In water, 1,400 mg/L at 25 °C
    • Solubility in water, g/100ml at 25 °C: 0.19

  • Synonyms

    • 1-Chloro-1,1-difluoroethane
    • 75-68-3
    • HCFC-142b
    • Genetron 142b
    • Ethane, 1-chloro-1,1-difluoro-
    • Freon 142b
    • Propellant 142b
    • Genetron 101
    • Gentron 142B
    • Fluorocarbon FC142b
    • Hydrochlorofluorocarbon 142b
    • Chloroethylidene fluoride
    • 1,1-Difluoro-1-chloroethane
    • Fluorocarbon 142b
    • Isotron 142b
    • R-142b
    • CFC 142b
    • FREON 142
    • Difluoro-1-chloroethane
    • FC142b
    • Chlorofluorocarbon 142b
    • FUC3XHA6GY
    • UNII-FUC3XHA6GY
    • F 142b
    • HSDB 2881
    • EINECS 200-891-8
    • UN2517
    • BRN 1731584
    • .alpha.-Chloroethylidene fluoride
    • Dymel 142
    • CH3CF2Cl
    • PROPELLANT-142B
    • SOLKANE 142B
    • HCFC 142b
    • FREON-142B
    • FC 142b
    • DTXSID9023960
    • R 142b
    • EC 200-891-8
    • UN 2517
    • CHLORO-1,1-DIFLUOROETHANE, 1-
    • 1-CHLORO-1,1-DIFLUOROETHANE [HSDB]
    • Monochlorodifluoroethane
    • Difluorochloroethanes
    • Difluoro1chloroethane
    • Ethane, chlorodifuoro-
    • CH3CClF2
    • 1,1Difluoro1chloroethane
    • 1Chloro1,1difluoroethane
    • Refrigerant gas R 142b
    • HCFC142b
    • DAIFLON 142B
    • 1,1,1-Chlorodifluoroethane
    • 1,1,1-Difluorochloroethane
    • Ethane, 1chloro1,1difluoro
    • SCHEMBL30184
    • 1-Chloro-1,1-difluoroethan
    • HCFC 142 b
    • FRON 142B
    • alpha-Chloroethylidene fluoride
    • CFC-142B
    • DTXCID903960
    • FKW 142B
    • HFA 142B
    • REFRIGERANT GAS R-142B
    • R142B
    • 1-Chloro-1,1-difluoroethan (Dutch)
    • 1-Chloro-1,1-difluoroethane, 98%
    • AKOS007930004
    • 1-Chloro-1,1-Difluoroethane (Hcfc142B)
    • DB-055977
    • HYDROCHLOROFLUOROCARBON 142B [INCI]
    • NS00005610
    • Q161601
    • 1-Chloro-1,1-difluoroethane 100 microg/mL in Methanol
    • 1-Chloro-1,1-difluoroethane or Refrigerant gas R 142b
    • 1-Chloro-1,1-difluoroethane 1000 microg/mL in Methanol
    • 1-Chloro-1,1-difluoroethane or Refrigerant gas R 142b [UN2517] [Flammable gas]

  • Applications

    1-Chloro-1,1-difluoroethane (CAS 75-68-3) is a halogenated hydrocarbon primarily used as a specialty solvent and as an intermediate in fluorinated chemical syntheses. In industrial manufacturing it serves as a cleaning and degreasing solvent for metal parts and as a processing aid in coatings, inks, and adhesive formulations. It also functions as a fluorinated-chemistry intermediate for the synthesis of fluorinated monomers and additives used in plastics and coatings. In electronics and precision equipment manufacturing it is employed for controlled component cleaning under appropriate safety and environmental regulations. Depending on local regulations, it may be evaluated for use in certain polymer processing or formulation contexts as a solvent rather than a reactive reagent.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 885.95
    methanol 1527.24
    isopropanol 641.93
    water 605.34
    ethyl acetate 581.65
    n-propanol 533.65
    acetone 1740.87
    n-butanol 408.61
    acetonitrile 1229.8
    DMF 3870.72
    toluene 346.81
    isobutanol 387.61
    1,4-dioxane 1067.91
    methyl acetate 855.4
    THF 1205.81
    2-butanone 794.14
    n-pentanol 304.42
    sec-butanol 446.7
    n-hexane 123.75
    ethylene glycol 494.57
    NMP 2270.7
    cyclohexane 99.29
    DMSO 2501.96
    n-butyl acetate 204.57
    n-octanol 222.71
    chloroform 738.51
    n-propyl acetate 389.15
    acetic acid 1073.38
    dichloromethane 944.97
    cyclohexanone 682.2
    propylene glycol 396.43
    isopropyl acetate 346.63
    DMAc 2683.61
    2-ethoxyethanol 873.44
    isopentanol 330.55
    n-heptane 60.91
    ethyl formate 693.3
    1,2-dichloroethane 666.81
    n-hexanol 183.06
    2-methoxyethanol 1577.83
    isobutyl acetate 207.43
    tetrachloromethane 161.55
    n-pentyl acetate 197.43
    transcutol 1068.75
    n-heptanol 119.67
    ethylbenzene 220.26
    MIBK 358.59
    2-propoxyethanol 520.78
    tert-butanol 731.88
    MTBE 546.78
    2-butoxyethanol 269.69
    propionic acid 544.19
    o-xylene 321.37
    formic acid 1042.8
    diethyl ether 603.55
    m-xylene 279.65
    p-xylene 282.61
    chlorobenzene 307.44
    dimethyl carbonate 641.86
    n-octane 38.0
    formamide 1559.78
    cyclopentanone 937.38
    2-pentanone 550.97
    anisole 589.67
    cyclopentyl methyl ether 573.55
    gamma-butyrolactone 1185.38
    1-methoxy-2-propanol 1058.8
    pyridine 748.66
    3-pentanone 519.09
    furfural 1354.95
    n-dodecane 39.93
    diethylene glycol 558.86
    diisopropyl ether 202.37
    tert-amyl alcohol 528.96
    acetylacetone 877.04
    n-hexadecane 41.81
    acetophenone 564.57
    methyl propionate 651.85
    isopentyl acetate 172.62
    trichloroethylene 942.09
    n-nonanol 197.83
    cyclohexanol 362.65
    benzyl alcohol 406.73
    2-ethylhexanol 126.53
    isooctanol 103.54
    dipropyl ether 249.6
    1,2-dichlorobenzene 303.12
    ethyl lactate 300.43
    propylene carbonate 592.96
    n-methylformamide 1766.52
    2-pentanol 303.3
    n-pentane 132.59
    1-propoxy-2-propanol 330.87
    1-methoxy-2-propyl acetate 313.99
    2-(2-methoxypropoxy) propanol 439.32
    mesitylene 198.55
    ε-caprolactone 601.06
    p-cymene 110.91
    epichlorohydrin 1069.81
    1,1,1-trichloroethane 491.67
    2-aminoethanol 606.87
    morpholine-4-carbaldehyde 2104.16
    sulfolane 1209.64
    2,2,4-trimethylpentane 63.79
    2-methyltetrahydrofuran 702.42
    n-hexyl acetate 324.74
    isooctane 43.95
    2-(2-butoxyethoxy)ethanol 467.07
    sec-butyl acetate 238.36
    tert-butyl acetate 372.19
    decalin 69.18
    glycerin 611.36
    diglyme 968.37
    acrylic acid 618.92
    isopropyl myristate 157.31
    n-butyric acid 439.95
    acetyl acetate 465.12
    di(2-ethylhexyl) phthalate 156.3
    ethyl propionate 434.89
    nitromethane 2518.4
    1,2-diethoxyethane 390.66
    benzonitrile 452.38
    trioctyl phosphate 117.08
    1-bromopropane 380.16
    gamma-valerolactone 1562.42
    n-decanol 152.24
    triethyl phosphate 156.06
    4-methyl-2-pentanol 194.64
    propionitrile 593.57
    vinylene carbonate 656.35
    1,1,2-trichlorotrifluoroethane 787.03
    DMS 390.46
    cumene 166.34
    2-octanol 114.56
    2-hexanone 393.29
    octyl acetate 204.65
    limonene 149.11
    1,2-dimethoxyethane 1628.03
    ethyl orthosilicate 148.07
    tributyl phosphate 148.02
    diacetone alcohol 481.16
    N,N-dimethylaniline 545.75
    acrylonitrile 850.52
    aniline 435.65
    1,3-propanediol 592.71
    bromobenzene 274.6
    dibromomethane 572.64
    1,1,2,2-tetrachloroethane 699.52
    2-methyl-cyclohexyl acetate 183.21
    tetrabutyl urea 256.41
    diisobutyl methanol 102.23
    2-phenylethanol 220.59
    styrene 272.52
    dioctyl adipate 227.51
    dimethyl sulfate 931.02
    ethyl butyrate 240.9
    methyl lactate 493.4
    butyl lactate 190.64
    diethyl carbonate 201.96
    propanediol butyl ether 339.78
    triethyl orthoformate 188.79
    p-tert-butyltoluene 112.86
    methyl 4-tert-butylbenzoate 378.6
    morpholine 1091.87
    tert-butylamine 497.51
    n-dodecanol 124.55
    dimethoxymethane 1789.33
    ethylene carbonate 498.24
    cyrene 458.21
    2-ethoxyethyl acetate 310.05
    2-ethylhexyl acetate 138.82
    1,2,4-trichlorobenzene 363.26
    4-methylpyridine 903.84
    dibutyl ether 242.28
    2,6-dimethyl-4-heptanol 102.23
    DEF 948.72
    dimethyl isosorbide 547.15
    tetrachloroethylene 462.97
    eugenol 363.72
    triacetin 454.77
    span 80 308.97
    1,4-butanediol 288.1
    1,1-dichloroethane 597.71
    2-methyl-1-pentanol 249.9
    methyl formate 1539.38
    2-methyl-1-butanol 338.17
    n-decane 56.34
    butyronitrile 480.24
    3,7-dimethyl-1-octanol 192.75
    1-chlorooctane 143.84
    1-chlorotetradecane 77.34
    n-nonane 55.39
    undecane 45.66
    tert-butylcyclohexane 68.44
    cyclooctane 51.58
    cyclopentanol 416.39
    tetrahydropyran 595.62
    tert-amyl methyl ether 465.56
    2,5,8-trioxanonane 736.11
    1-hexene 249.1
    2-isopropoxyethanol 490.83
    2,2,2-trifluoroethanol 644.85
    methyl butyrate 523.13

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction