1-(4-Methoxyphenyl)-1-propanol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    5349-60-0

    Molecular formula
    C10H14O2

    SMILES
    CCC(C1=CC=C(C=C1)OC)O

    Safety labels

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fragrance
    Sweet 78.96%
    Floral 69.23%
    Vanilla 58.39%
    Anisic 50.29%
    Balsamic 46.56%
    Powdery 40.62%
    Aromatic 39.69%
    Hawthorn 37.68%
    Spicy 37.04%
    Fruity 36.65%

     

    Flavor
    Sweet 88.86%
    Floral 66.21%
    Balsam 46.05%
    Powdery 45.65%
    Vanilla 42.99%
    Spicy 40.26%
    Flower 38.46%
    Fruity 38.11%
    Bitter 34.37%
    Hawthorn 30.94%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.9

    pKa est.
    7.76 (neutral)

    Molecular weight
    166.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    265°C

    Flash point

    • 114.77 ˚C est.

  • Synonyms

    • 5349-60-0
    • 1-(4-Methoxyphenyl)-1-propanol
    • Benzenemethanol, .alpha.-ethyl-4-methoxy-
    • NSC 1264
    • NSC 406923
    • EINECS 226-315-5
    • Benzenemethanol, alpha-ethyl-4-methoxy-
    • AI3-09427
    • DTXSID40884149
    • EC 226-315-5
    • RefChem:74514
    • DTXCID50973210
    • RELLLNVFFUWXHI-UHFFFAOYSA-N
    • 1-(4-methoxyphenyl)propan-1-ol
    • rac-1-(4'-Methoxyphenyl)propanol
    • Benzyl alcohol, .alpha.-ethyl-p-methoxy-
    • 4-methoxyphenylpropanol
    • (R)-1-(4-Methoxyphenyl)propanol
    • (S)-1-(4-Methoxyphenyl)propanol
    • MFCD00021914
    • 73854-04-3
    • a-Ethyl-4-methoxy-benzenemethanol
    • alpha-Ethyl-p-methoxybenzyl alcohol
    • alpha-Ethyl-4-methoxybenzenemethanol
    • ALPHA-ETHYL-P-ANISYL ALCOHOL
    • p-methoxyphenylpropanol
    • SCHEMBL615718
    • orb3023465
    • SCHEMBL10606992
    • SCHEMBL10903587
    • NSC1264
    • rac-1-(4 inverted exclamation mark -Methoxyphenyl)propanol
    • 1-(4-Methoxyphenyl)-propan-1-ol
    • NSC-1264
    • NSC406923
    • alpha-ethyl-para-methoxybenzyl alcohol
    • AKOS000125165
    • AKOS022257950
    • Benzyl alcohol, alpha-ethyl-p-methoxy-
    • NSC-406923
    • SB83928
    • NS00001587
    • EN300-73558
    • N12428
    • F819580
    • Z228586320
    • 5349-60-0

  • Applications

    1-(4-Methoxyphenyl)-1-propanol (CAS 5349-60-0) is commonly used as a building block and fragrance-related intermediate in several industries. In perfumery and cosmetics, it may serve as a fragrance ingredient or precursor to anisyl aroma compounds; in household and cleaning products, it may be used as a fragrance additive in formulations; in pharmaceutical synthesis, it is commonly evaluated as an intermediate for the preparation of more complex fine chemicals; in polymers and coatings, it may be used as a building block for specialty monomers or scent-containing materials. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 872.15
    methanol 1109.7
    isopropanol 540.7
    water 2.64
    ethyl acetate 1092.08
    n-propanol 720.54
    acetone 1448.26
    n-butanol 584.51
    acetonitrile 975.63
    DMF 1603.13
    toluene 197.04
    isobutanol 383.43
    1,4-dioxane 1417.83
    methyl acetate 905.0
    THF 1572.37
    2-butanone 928.24
    n-pentanol 360.25
    sec-butanol 410.52
    n-hexane 34.66
    ethylene glycol 307.69
    NMP 1083.49
    cyclohexane 49.37
    DMSO 3105.11
    n-butyl acetate 566.63
    n-octanol 100.13
    chloroform 1456.71
    n-propyl acetate 486.63
    acetic acid 1141.36
    dichloromethane 1735.82
    cyclohexanone 925.34
    propylene glycol 325.82
    isopropyl acetate 455.01
    DMAc 906.01
    2-ethoxyethanol 903.17
    isopentanol 456.88
    n-heptane 15.78
    ethyl formate 524.76
    1,2-dichloroethane 1501.85
    n-hexanol 292.19
    2-methoxyethanol 1463.91
    isobutyl acetate 239.48
    tetrachloromethane 251.19
    n-pentyl acetate 202.0
    transcutol 3314.54
    n-heptanol 102.74
    ethylbenzene 98.62
    MIBK 354.91
    2-propoxyethanol 682.89
    tert-butanol 878.46
    MTBE 818.99
    2-butoxyethanol 279.12
    propionic acid 713.99
    o-xylene 124.87
    formic acid 663.34
    diethyl ether 1047.97
    m-xylene 119.83
    p-xylene 113.61
    chlorobenzene 455.0
    dimethyl carbonate 366.73
    n-octane 5.67
    formamide 1396.74
    cyclopentanone 1288.79
    2-pentanone 732.47
    anisole 402.26
    cyclopentyl methyl ether 682.19
    gamma-butyrolactone 1554.4
    1-methoxy-2-propanol 852.56
    pyridine 903.78
    3-pentanone 555.85
    furfural 1168.64
    n-dodecane 4.77
    diethylene glycol 642.35
    diisopropyl ether 183.41
    tert-amyl alcohol 618.84
    acetylacetone 838.3
    n-hexadecane 5.78
    acetophenone 316.88
    methyl propionate 788.09
    isopentyl acetate 425.56
    trichloroethylene 2436.27
    n-nonanol 87.28
    cyclohexanol 387.37
    benzyl alcohol 286.2
    2-ethylhexanol 162.8
    isooctanol 87.23
    dipropyl ether 253.42
    1,2-dichlorobenzene 416.53
    ethyl lactate 198.65
    propylene carbonate 650.34
    n-methylformamide 1122.09
    2-pentanol 334.8
    n-pentane 32.31
    1-propoxy-2-propanol 418.53
    1-methoxy-2-propyl acetate 558.45
    2-(2-methoxypropoxy) propanol 371.3
    mesitylene 83.49
    ε-caprolactone 771.85
    p-cymene 69.02
    epichlorohydrin 1919.16
    1,1,1-trichloroethane 941.5
    2-aminoethanol 539.7
    morpholine-4-carbaldehyde 1180.47
    sulfolane 1868.61
    2,2,4-trimethylpentane 28.41
    2-methyltetrahydrofuran 1025.43
    n-hexyl acetate 273.08
    isooctane 21.26
    2-(2-butoxyethoxy)ethanol 554.65
    sec-butyl acetate 274.85
    tert-butyl acetate 569.05
    decalin 31.04
    glycerin 484.99
    diglyme 1168.76
    acrylic acid 682.94
    isopropyl myristate 98.59
    n-butyric acid 799.99
    acetyl acetate 531.84
    di(2-ethylhexyl) phthalate 104.3
    ethyl propionate 389.28
    nitromethane 2645.67
    1,2-diethoxyethane 792.24
    benzonitrile 352.65
    trioctyl phosphate 72.5
    1-bromopropane 555.44
    gamma-valerolactone 1464.43
    n-decanol 61.27
    triethyl phosphate 158.39
    4-methyl-2-pentanol 175.75
    propionitrile 607.34
    vinylene carbonate 597.05
    1,1,2-trichlorotrifluoroethane 1201.92
    DMS 367.99
    cumene 71.25
    2-octanol 63.1
    2-hexanone 429.68
    octyl acetate 118.91
    limonene 109.35
    1,2-dimethoxyethane 1160.95
    ethyl orthosilicate 159.33
    tributyl phosphate 122.98
    diacetone alcohol 581.64
    N,N-dimethylaniline 206.99
    acrylonitrile 819.63
    aniline 432.84
    1,3-propanediol 693.73
    bromobenzene 444.76
    dibromomethane 988.66
    1,1,2,2-tetrachloroethane 1722.54
    2-methyl-cyclohexyl acetate 226.93
    tetrabutyl urea 140.47
    diisobutyl methanol 100.32
    2-phenylethanol 242.19
    styrene 150.53
    dioctyl adipate 169.94
    dimethyl sulfate 644.11
    ethyl butyrate 336.5
    methyl lactate 311.6
    butyl lactate 191.13
    diethyl carbonate 252.66
    propanediol butyl ether 316.78
    triethyl orthoformate 232.13
    p-tert-butyltoluene 69.76
    methyl 4-tert-butylbenzoate 224.17
    morpholine 1652.66
    tert-butylamine 482.38
    n-dodecanol 44.71
    dimethoxymethane 1068.45
    ethylene carbonate 528.31
    cyrene 323.73
    2-ethoxyethyl acetate 464.33
    2-ethylhexyl acetate 322.72
    1,2,4-trichlorobenzene 503.44
    4-methylpyridine 685.58
    dibutyl ether 185.32
    2,6-dimethyl-4-heptanol 100.32
    DEF 830.25
    dimethyl isosorbide 559.12
    tetrachloroethylene 1087.44
    eugenol 242.89
    triacetin 347.67
    span 80 251.83
    1,4-butanediol 254.14
    1,1-dichloroethane 1028.85
    2-methyl-1-pentanol 320.67
    methyl formate 831.06
    2-methyl-1-butanol 420.75
    n-decane 8.77
    butyronitrile 521.43
    3,7-dimethyl-1-octanol 125.38
    1-chlorooctane 63.45
    1-chlorotetradecane 23.1
    n-nonane 8.16
    undecane 6.18
    tert-butylcyclohexane 30.28
    cyclooctane 16.33
    cyclopentanol 426.6
    tetrahydropyran 1140.7
    tert-amyl methyl ether 467.05
    2,5,8-trioxanonane 691.17
    1-hexene 151.85
    2-isopropoxyethanol 496.07
    2,2,2-trifluoroethanol 436.7
    methyl butyrate 506.07

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction