1-(2,2-Dimethoxyethoxy)-4-methyl-benzene

Overview IFRA Request a quote

  • Identifiers

    CAS number
    6324-78-3

    Molecular formula
    C11H16O3

    SMILES
    CC1=CC=C(C=C1)OCC(OC)OC

    Safety labels

    Flammable
    Flammable

  • Odor profile

    Fragrance
    Green 67.63%
    Floral 67.09%
    Earthy 46.41%
    Fresh 41.65%
    Fruity 40.34%
    Sweet 36.53%
    Leafy 35.47%
    Rose 35.41%
    Hyacinth 34.11%
    Anisic 29.45%

     

    Flavor
    Floral 60.54%
    Fruity 60.26%
    Green 51.11%
    Bitter 47.5%
    Sweet 44.88%
    Earthy 35.79%
    Musty 30.86%
    Spicy 29.29%
    Rose 29.28%
    Wine 28.17%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.1

    pKa est.
    6.69 (neutral)

    Molecular weight
    196.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    255°C

    Flash point

    • 98.22 ˚C est.

  • Synonyms

    • 6324-78-3
    • 1-(2,2-dimethoxyethoxy)-4-methylbenzene
    • 4-(2,2-Dimethoxyethoxy)toluene
    • Benzene, 1-(2,2-dimethoxyethoxy)-4-methyl-
    • p-(2,2-Dimethoxyethoxy)toluene
    • 2RN4D1ZN4O
    • 1-(2,2-dimethoxyethoxy)-4-methyl-benzene
    • EINECS 228-689-5
    • NSC 29902
    • NSC-29902
    • Acetaldehyde, p-tolyloxy-, dimethylacetal
    • p-Methylphenoxyacetaldehyde dimethyl acetal
    • DTXSID2064234
    • RefChem:420255
    • DTXCID2043799
    • 228-689-5
    • 1-(2,2-DIMETHOXY-ETHOXY)-4-METHYL-BENZENE
    • NSC29902
    • UNII-2RN4D1ZN4O
    • Acetaldehyde, dimethylacetal
    • SCHEMBL17996498
    • QRKQKOWDVJJBOE-UHFFFAOYSA-N
    • AKOS006293125
    • Benzene,2-dimethoxyethoxy)-4-methyl-
    • para-cresyl oxyacetaldehyde dimethyl acetal
    • DB-325812
    • NS00012134
    • 6324-78-3

  • Applications

    1-(2,2-Dimethoxyethoxy)-4-methyl-benzene (CAS 6324-78-3) is typically employed as an intermediate in organic synthesis; it can function as a solvent or co-solvent in industrial formulations such as coatings, inks, and cleaning products; it may serve as a precursor for specialty polymers and resin formulations; in perfumery it can act as a fragrance solvent or fixative; and it can be used as a reactive diluent or monomer in UV-curable coatings.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 872.06
    methanol 991.98
    isopropanol 444.36
    water 11.28
    ethyl acetate 1041.01
    n-propanol 556.58
    acetone 227.19
    n-butanol 496.36
    acetonitrile 639.44
    DMF 193.83
    toluene 192.69
    isobutanol 296.73
    1,4-dioxane 1747.43
    methyl acetate 569.38
    THF 668.84
    2-butanone 245.78
    n-pentanol 306.12
    sec-butanol 392.96
    n-hexane 25.6
    ethylene glycol 285.82
    NMP 99.57
    cyclohexane 127.09
    DMSO 444.19
    n-butyl acetate 231.9
    n-octanol 70.22
    chloroform 2000.35
    n-propyl acetate 273.75
    acetic acid 1255.6
    dichloromethane 1737.32
    cyclohexanone 324.58
    propylene glycol 272.29
    isopropyl acetate 291.12
    DMAc 267.95
    2-ethoxyethanol 980.41
    isopentanol 310.78
    n-heptane 30.22
    ethyl formate 460.19
    1,2-dichloroethane 904.89
    n-hexanol 230.02
    2-methoxyethanol 1379.46
    isobutyl acetate 137.74
    tetrachloromethane 257.03
    n-pentyl acetate 96.74
    transcutol 1196.03
    n-heptanol 89.73
    ethylbenzene 102.16
    MIBK 113.06
    2-propoxyethanol 454.42
    tert-butanol 682.71
    MTBE 409.7
    2-butoxyethanol 217.23
    propionic acid 475.83
    o-xylene 134.25
    formic acid 586.68
    diethyl ether 702.01
    m-xylene 103.63
    p-xylene 138.79
    chlorobenzene 278.62
    dimethyl carbonate 129.79
    n-octane 11.16
    formamide 754.55
    cyclopentanone 193.17
    2-pentanone 192.06
    anisole 256.2
    cyclopentyl methyl ether 260.9
    gamma-butyrolactone 346.3
    1-methoxy-2-propanol 608.32
    pyridine 697.52
    3-pentanone 168.49
    furfural 513.92
    n-dodecane 9.3
    diethylene glycol 480.53
    diisopropyl ether 98.07
    tert-amyl alcohol 474.06
    acetylacetone 300.91
    n-hexadecane 10.32
    acetophenone 184.17
    methyl propionate 358.45
    isopentyl acetate 185.58
    trichloroethylene 1427.0
    n-nonanol 70.23
    cyclohexanol 411.77
    benzyl alcohol 255.68
    2-ethylhexanol 131.05
    isooctanol 69.71
    dipropyl ether 175.88
    1,2-dichlorobenzene 259.63
    ethyl lactate 129.8
    propylene carbonate 279.63
    n-methylformamide 265.72
    2-pentanol 255.97
    n-pentane 35.77
    1-propoxy-2-propanol 244.86
    1-methoxy-2-propyl acetate 231.23
    2-(2-methoxypropoxy) propanol 182.58
    mesitylene 66.46
    ε-caprolactone 378.3
    p-cymene 63.41
    epichlorohydrin 716.64
    1,1,1-trichloroethane 739.91
    2-aminoethanol 479.26
    morpholine-4-carbaldehyde 418.7
    sulfolane 246.97
    2,2,4-trimethylpentane 24.08
    2-methyltetrahydrofuran 510.43
    n-hexyl acetate 117.25
    isooctane 13.54
    2-(2-butoxyethoxy)ethanol 270.25
    sec-butyl acetate 168.2
    tert-butyl acetate 235.44
    decalin 36.95
    glycerin 426.44
    diglyme 636.84
    acrylic acid 391.46
    isopropyl myristate 53.51
    n-butyric acid 714.48
    acetyl acetate 540.1
    di(2-ethylhexyl) phthalate 60.15
    ethyl propionate 253.92
    nitromethane 1114.8
    1,2-diethoxyethane 404.85
    benzonitrile 223.53
    trioctyl phosphate 36.96
    1-bromopropane 430.03
    gamma-valerolactone 469.34
    n-decanol 51.95
    triethyl phosphate 112.14
    4-methyl-2-pentanol 108.83
    propionitrile 377.97
    vinylene carbonate 325.53
    1,1,2-trichlorotrifluoroethane 639.39
    DMS 147.99
    cumene 67.54
    2-octanol 48.63
    2-hexanone 151.11
    octyl acetate 67.29
    limonene 92.87
    1,2-dimethoxyethane 942.67
    ethyl orthosilicate 125.86
    tributyl phosphate 53.27
    diacetone alcohol 238.71
    N,N-dimethylaniline 136.58
    acrylonitrile 386.79
    aniline 340.45
    1,3-propanediol 778.86
    bromobenzene 279.53
    dibromomethane 1045.47
    1,1,2,2-tetrachloroethane 1175.25
    2-methyl-cyclohexyl acetate 140.67
    tetrabutyl urea 58.62
    diisobutyl methanol 73.16
    2-phenylethanol 186.83
    styrene 140.81
    dioctyl adipate 94.1
    dimethyl sulfate 140.05
    ethyl butyrate 224.88
    methyl lactate 162.76
    butyl lactate 77.97
    diethyl carbonate 191.4
    propanediol butyl ether 129.01
    triethyl orthoformate 177.74
    p-tert-butyltoluene 60.55
    methyl 4-tert-butylbenzoate 124.94
    morpholine 1616.93
    tert-butylamine 398.18
    n-dodecanol 42.37
    dimethoxymethane 367.24
    ethylene carbonate 292.51
    cyrene 158.54
    2-ethoxyethyl acetate 197.59
    2-ethylhexyl acetate 142.01
    1,2,4-trichlorobenzene 293.51
    4-methylpyridine 402.02
    dibutyl ether 115.65
    2,6-dimethyl-4-heptanol 73.16
    DEF 273.84
    dimethyl isosorbide 258.93
    tetrachloroethylene 891.03
    eugenol 135.23
    triacetin 164.53
    span 80 140.52
    1,4-butanediol 271.35
    1,1-dichloroethane 746.36
    2-methyl-1-pentanol 237.23
    methyl formate 236.86
    2-methyl-1-butanol 303.36
    n-decane 15.29
    butyronitrile 382.73
    3,7-dimethyl-1-octanol 75.95
    1-chlorooctane 54.64
    1-chlorotetradecane 23.99
    n-nonane 14.4
    undecane 11.12
    tert-butylcyclohexane 28.41
    cyclooctane 31.81
    cyclopentanol 253.0
    tetrahydropyran 980.93
    tert-amyl methyl ether 271.72
    2,5,8-trioxanonane 407.63
    1-hexene 97.03
    2-isopropoxyethanol 439.6
    2,2,2-trifluoroethanol 405.87
    methyl butyrate 314.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction