Ambroxan alt. Ambermor Ambrofix Aroma Chemical
CAS# 6790-58-5
Woody, Amber, Dry, Cedar, Musk
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Ambroxan is the trade name registered by Kao Corporation for the molecule (-)-Ambroxide, also known by other names such as Ambroxide, Ambrofix (Givaudan), Ambrox and Cetalox (Firmenich). Although it is the core component responsible for the characteristic scent of natural ambergris, Ambroxan today is mainly semi-synthetic or fully synthetic. It is commonly produced from sclareol extracted from clary sage, providing a renewable plant-based origin, or via biotechnology through the fermentation of sugarcane. The history of this material began in the 1950s, when chemists at Firmenich in Switzerland sought an alternative to expensive ambergris. In 1950, Max Stoll and M. Hinder identified (-)-Ambroxide as the key odorant of ambergris, then refined a synthesis route from sclareol-opening a new era for perfumery. In its pure state, Ambroxan appears as white crystalline solid or crystalline powder.
Description
Its odor is described as dry, clean, strongly woody and ambery, with a light salty, marine-mineral nuance. Although it sits in the amber/woody/“clean animalic” family, Ambroxan is not harsh when smelled neat; instead, it has exceptionally strong diffusion in the air, evoking the feel of clean skin with a soft sweetness. With lasting power on a blotter ranging from weeks to months, it functions in the base and acts as an excellent diffusive booster and odor modifier. In a perfume structure, Ambroxan provides a solid backbone that makes the overall scent fuller, smoother, longer-lasting, and more radiating, while also adding a modern, minimalist, gender-neutral effect. It is often used to recreate ambergris accords, or paired with Iso E Super as a classic duo for “skin-like” fragrances with a dry woody, highly diffusive effect. When used with citrus notes, Ambroxan helps extend longevity and makes these volatile notes feel more structured and sharper. Because it is solid, it is typically pre-diluted to 10% in solvents such as DPG, DEP, or alcohol for easier handling.
Applications
Ambroxan is highly versatile, used across men’s, women’s, and unisex fine fragrance, as well as personal-care products (body wash, shampoo, skin creams) thanks to its strong stability and low tendency to discolor formulas. It also performs extremely well on fabrics, which is why it is widely used in laundry detergents, fabric softeners, and scented candles. Usage levels are flexible: from below 1% up to around 0.5–5% in typical formulas, or even 10–20%+ in fragrance concentrates designed to showcase it. IFRA does not set a specific concentration limit for Ambroxan because it is considered very safe and low-irritant, provided good manufacturing practice is followed. For storage, keep it tightly sealed in a dry, cool, well-ventilated place away from direct sunlight.
In the market, Ambroxan underpins many bestsellers-for example Juliette Has A Gun Not A Perfume, built around Cetalox in alcohol; Le Labo Another 13, which uses a large amount alongside musks and oakmoss; Dior Sauvage (Eau de Toilette), where it contributes lift and a modern masculine edge; and Maison Francis Kurkdjian Baccarat Rouge 540, which relies on it for diffusion and a characteristic mineral effect. Finally, in Perfume and Flavor Chemicals, Steffen Arctander described it as a powerful, dry, persistent woody-amber odor with almost no overt animalic note, carrying a subtle labdanum-like sweetness, and noted its use in fine perfumery as an odor modifier and base note for Amber, Chypre, Fougere, Woody, and Oriental accords.
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Technical standards
Technical standards
| Physical appearance | Crystal | Conform |
| Color | White | Conform |
| Flash point | ≥ 161.0°C | Conform |
| Boiling point | 121.0°C | Conform |
| Purity | ≥ 98.0% | Conform |
Solubility @25˚C
Solubility @25˚C
| Solvent | Solubility (g/L) |
|---|---|
| ethanol | 247.02 |
| methanol | 269.64 |
| isopropanol | 215.21 |
| water | 3.61 |
| ethyl acetate | 559.74 |
| n-propanol | 294.38 |
| acetone | 553.82 |
| n-butanol | 290.95 |
| acetonitrile | 621.71 |
| DMF | 559.78 |
| toluene | 873.81 |
| isobutanol | 243.89 |
| 1,4-dioxane | 1208.22 |
| methyl acetate | 525.25 |
| THF | 1811.77 |
| 2-butanone | 477.13 |
| n-pentanol | 148.32 |
| sec-butanol | 172.91 |
| n-hexane | 63.51 |
| ethylene glycol | 54.43 |
| NMP | 740.75 |
| cyclohexane | 301.73 |
| DMSO | 293.14 |
| n-butyl acetate | 570.33 |
| n-octanol | 165.42 |
| chloroform | 1887.04 |
| n-propyl acetate | 336.45 |
| acetic acid | 306.36 |
| dichloromethane | 1645.01 |
| cyclohexanone | 1151.75 |
| propylene glycol | 67.46 |
| isopropyl acetate | 437.4 |
| DMAc | 422.03 |
| 2-ethoxyethanol | 196.71 |
| isopentanol | 251.89 |
| n-heptane | 115.91 |
| ethyl formate | 391.87 |
| 1,2-dichloroethane | 770.31 |
| n-hexanol | 370.59 |
| 2-methoxyethanol | 353.93 |
| isobutyl acetate | 309.88 |
| tetrachloromethane | 366.59 |
| n-pentyl acetate | 376.49 |
| transcutol | 750.74 |
| n-heptanol | 193.58 |
| ethylbenzene | 276.22 |
| MIBK | 335.35 |
| 2-propoxyethanol | 499.91 |
| tert-butanol | 229.43 |
| MTBE | 309.4 |
| 2-butoxyethanol | 286.52 |
| propionic acid | 294.0 |
| o-xylene | 406.13 |
| formic acid | 102.26 |
| diethyl ether | 444.87 |
| m-xylene | 512.83 |
| p-xylene | 383.27 |
| chlorobenzene | 931.23 |
| dimethyl carbonate | 255.92 |
| n-octane | 35.77 |
| formamide | 146.16 |
| cyclopentanone | 1153.6 |
| 2-pentanone | 430.19 |
| anisole | 397.28 |
| cyclopentyl methyl ether | 781.04 |
| gamma-butyrolactone | 1286.02 |
| 1-methoxy-2-propanol | 285.8 |
| pyridine | 1118.6 |
| 3-pentanone | 391.43 |
| furfural | 950.79 |
| n-dodecane | 30.08 |
| diethylene glycol | 275.66 |
| diisopropyl ether | 195.12 |
| tert-amyl alcohol | 152.98 |
| acetylacetone | 571.03 |
| n-hexadecane | 35.87 |
| acetophenone | 377.93 |
| methyl propionate | 450.77 |
| isopentyl acetate | 523.95 |
| trichloroethylene | 1437.43 |
| n-nonanol | 153.85 |
| cyclohexanol | 425.38 |
| benzyl alcohol | 298.08 |
| 2-ethylhexanol | 247.29 |
| isooctanol | 162.23 |
| dipropyl ether | 370.4 |
| 1,2-dichlorobenzene | 720.74 |
| ethyl lactate | 150.27 |
| propylene carbonate | 751.59 |
| n-methylformamide | 348.64 |
| 2-pentanol | 172.88 |
| n-pentane | 94.0 |
| 1-propoxy-2-propanol | 349.44 |
| 1-methoxy-2-propyl acetate | 526.34 |
| 2-(2-methoxypropoxy) propanol | 252.4 |
| mesitylene | 320.62 |
| ε-caprolactone | 929.58 |
| p-cymene | 249.78 |
| epichlorohydrin | 1109.93 |
| 1,1,1-trichloroethane | 858.26 |
| 2-aminoethanol | 121.81 |
| morpholine-4-carbaldehyde | 815.07 |
| sulfolane | 828.6 |
| 2,2,4-trimethylpentane | 46.04 |
| 2-methyltetrahydrofuran | 1023.66 |
| n-hexyl acetate | 460.85 |
| isooctane | 43.32 |
| 2-(2-butoxyethoxy)ethanol | 313.52 |
| sec-butyl acetate | 276.32 |
| tert-butyl acetate | 425.02 |
| decalin | 98.2 |
| glycerin | 103.53 |
| diglyme | 639.28 |
| acrylic acid | 278.59 |
| isopropyl myristate | 192.08 |
| n-butyric acid | 437.82 |
| acetyl acetate | 479.05 |
| di(2-ethylhexyl) phthalate | 181.67 |
| ethyl propionate | 321.28 |
| nitromethane | 616.85 |
| 1,2-diethoxyethane | 412.0 |
| benzonitrile | 630.67 |
| trioctyl phosphate | 142.03 |
| 1-bromopropane | 538.59 |
| gamma-valerolactone | 1364.95 |
| n-decanol | 112.19 |
| triethyl phosphate | 191.15 |
| 4-methyl-2-pentanol | 144.22 |
| propionitrile | 551.7 |
| vinylene carbonate | 794.1 |
| 1,1,2-trichlorotrifluoroethane | 501.72 |
| DMS | 395.35 |
| cumene | 192.78 |
| 2-octanol | 122.29 |
| 2-hexanone | 283.63 |
| octyl acetate | 223.16 |
| limonene | 320.49 |
| 1,2-dimethoxyethane | 443.4 |
| ethyl orthosilicate | 188.49 |
| tributyl phosphate | 169.38 |
| diacetone alcohol | 286.66 |
| N,N-dimethylaniline | 252.91 |
| acrylonitrile | 603.09 |
| aniline | 564.95 |
| 1,3-propanediol | 194.72 |
| bromobenzene | 1086.89 |
| dibromomethane | 1055.1 |
| 1,1,2,2-tetrachloroethane | 1021.54 |
| 2-methyl-cyclohexyl acetate | 357.3 |
| tetrabutyl urea | 194.74 |
| diisobutyl methanol | 158.87 |
| 2-phenylethanol | 397.48 |
| styrene | 350.63 |
| dioctyl adipate | 242.41 |
| dimethyl sulfate | 287.64 |
| ethyl butyrate | 384.5 |
| methyl lactate | 167.66 |
| butyl lactate | 236.81 |
| diethyl carbonate | 273.8 |
| propanediol butyl ether | 196.32 |
| triethyl orthoformate | 292.17 |
| p-tert-butyltoluene | 236.89 |
| methyl 4-tert-butylbenzoate | 332.75 |
| morpholine | 1017.78 |
| tert-butylamine | 191.23 |
| n-dodecanol | 86.51 |
| dimethoxymethane | 566.14 |
| ethylene carbonate | 704.86 |
| cyrene | 265.35 |
| 2-ethoxyethyl acetate | 483.6 |
| 2-ethylhexyl acetate | 455.81 |
| 1,2,4-trichlorobenzene | 771.11 |
| 4-methylpyridine | 1068.71 |
| dibutyl ether | 233.99 |
| 2,6-dimethyl-4-heptanol | 158.87 |
| DEF | 421.93 |
| dimethyl isosorbide | 555.77 |
| tetrachloroethylene | 703.53 |
| eugenol | 285.34 |
| triacetin | 365.54 |
| span 80 | 248.03 |
| 1,4-butanediol | 70.14 |
| 1,1-dichloroethane | 766.68 |
| 2-methyl-1-pentanol | 148.45 |
| methyl formate | 330.95 |
| 2-methyl-1-butanol | 215.44 |
| n-decane | 51.93 |
| butyronitrile | 527.88 |
| 3,7-dimethyl-1-octanol | 167.12 |
| 1-chlorooctane | 170.91 |
| 1-chlorotetradecane | 73.09 |
| n-nonane | 49.34 |
| undecane | 37.93 |
| tert-butylcyclohexane | 71.14 |
| cyclooctane | 115.22 |
| cyclopentanol | 424.65 |
| tetrahydropyran | 1194.49 |
| tert-amyl methyl ether | 221.74 |
| 2,5,8-trioxanonane | 387.21 |
| 1-hexene | 160.0 |
| 2-isopropoxyethanol | 169.58 |
| 2,2,2-trifluoroethanol | 172.61 |
| methyl butyrate | 365.08 |
Scent© AI

Olfactory Pyramid
Notes
| Woody |
| Amber |
| Dry |
| Cedar |
| Musk |
| Maximum acceptable concentrations in the finished product (%) | |||
|---|---|---|---|
|
Category 1
Products applied to the lips
|
No restriction |
Category 7A
Rinse-off products applied to the hair with some hand contact
|
No restriction |
|
Category 2
Products applied to the axillae
|
No restriction |
Category 7B
Leave-on products applied to the hair with some hand contact
|
No restriction |
|
Category 3
Products applied to the face/body using fingertips
|
No restriction |
Category 8
Products with significant anogenital exposure
|
No restriction |
|
Category 4
Products related to fine fragrance
|
No restriction |
Category 9
Products with body and hand exposure, primarily rinse off
|
No restriction |
|
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
|
No restriction |
Category 10A
Household care products with mostly hand contact
|
No restriction |
|
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
|
No restriction |
Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
|
No restriction |
|
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
|
No restriction |
Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
|
No restriction |
|
Category 5D
Baby Creams, baby Oils and baby talc
|
No restriction |
Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
|
No restriction |
|
Category 6
Products with oral and lip exposure
|
No restriction |
Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
|
No restriction |
Shipping & Returns
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All orders will be processed within 1-2 business days from the time the order is confirmed. -
Free shipping is available for international retail orders valued at 500 USD or more. -
Delivery time is 1-3 business days for local areas, 3-7 days for suburban and nationwide deliveries, and 1-4 weeks for international orders. -
You have 30 days from the date of receipt to initiate the return process.
Certificates of Quality
-
Certificate of Analysis (COA)
Provides information on the physical and chemical properties of the product.Download -
IFRA Certificate of Conformity
Sets safety standards and guidelines for the product in manufacturing.Download -
Safety Data Sheet (SDS)
Provides important safety guidelines for transporting, storing, and using the product.Download