Mycostatin dihydrate

Overview IFRA Request a quote

  • Identifiers

    Molecular formula
    C47H75NO17

    SMILES
    C[C@@H]1[C@H]([C@@H]([C@@H]([C@@H](O1)OC\2CC(C(C(CC(=O)CC(C(CCC(CC(CC(CC(=O)OC(C(C(C(/C=C/C=C/CC/C=C/C=C/C=C/C=C2)C)O)C)C)O)O)O)O)O)O)C(=O)O)O)O)N)O

  • Odor profile

    Fragrance
    Odorless 36.38%
    Spicy 29.72%
    Sweet 28.89%
    Caramellic 22.53%
    Vanilla 21.15%
    Coconut 20.51%
    Woody 19.97%
    Nutty 19.83%
    Lactonic 19.42%
    Milky 18.7%

     

    Flavor
    Bitter 51.52%
    Minty 31.06%
    Sweet 22.49%
    Odorless 22.47%
    Cauliflower 20.83%
    Spice 20.61%
    Alkaline 20.38%
    Fenugreek 20.2%
    Leaves 20.05%
    Shrimp 19.94%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.3

    pKa est.
    7.04 (neutral)

    Molecular weight
    926.1 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    6265°C

    Flash point

    • 279.77 ˚C est.

  • Synonyms

    • Nystatin hydrate
    • Mycostatin dihydrate
    • Prestwick3_000517
    • BSPBio_000473
    • BPBio1_000521
    • CHEMBL4303481
    • HMS2090F05
    • HMS2096H15
    • HMS3713H15
    • DL-460
    • MFCD00036240
    • CCG-220517
    • AC-32594
    • AB00513851
    • AB00513851-02
    • SR-01000872664
    • SR-01000872664-1

  • Applications

    Mycostatin dihydrate is a polyene antifungal antibiotic used primarily as an active pharmaceutical ingredient in antifungal formulations. Common applications include topical dosage forms (creams, ointments) for skin fungal infections, oral dosage forms (suspensions) for mucosal use, inclusion in dermatology-focused pharmaceutical products, and use in research as a reference antifungal agent; veterinary dermatology products may also be considered where permitted.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.41
    methanol 14.78
    isopropanol 0.22
    water 0.94
    ethyl acetate 0.25
    n-propanol 0.77
    acetone 0.76
    n-butanol 0.36
    acetonitrile 0.27
    DMF 14.68
    toluene 0.2
    isobutanol 0.26
    1,4-dioxane 1.4
    methyl acetate 0.33
    THF 2.81
    2-butanone 0.55
    n-pentanol 0.31
    sec-butanol 0.19
    n-hexane 0.02
    ethylene glycol 4.3
    NMP 25.03
    cyclohexane 0.02
    DMSO 19.93
    n-butyl acetate 0.12
    n-octanol 0.16
    chloroform 0.4
    n-propyl acetate 0.17
    acetic acid 6.15
    dichloromethane 0.61
    cyclohexanone 1.23
    propylene glycol 3.23
    isopropyl acetate 0.13
    DMAc 11.5
    2-ethoxyethanol 3.27
    isopentanol 0.18
    n-heptane 0.02
    ethyl formate 0.53
    1,2-dichloroethane 0.37
    n-hexanol 0.18
    2-methoxyethanol 8.99
    isobutyl acetate 0.09
    tetrachloromethane 0.07
    n-pentyl acetate 0.22
    transcutol 7.13
    n-heptanol 0.22
    ethylbenzene 0.09
    MIBK 0.23
    2-propoxyethanol 2.75
    tert-butanol 0.12
    MTBE 0.07
    2-butoxyethanol 2.09
    propionic acid 1.26
    o-xylene 0.15
    formic acid 30.3
    diethyl ether 0.19
    m-xylene 0.15
    p-xylene 0.08
    chlorobenzene 0.12
    dimethyl carbonate 1.14
    n-octane 0.01
    formamide 17.35
    cyclopentanone 2.59
    2-pentanone 0.41
    anisole 0.26
    cyclopentyl methyl ether 0.68
    gamma-butyrolactone 3.6
    1-methoxy-2-propanol 3.98
    pyridine 1.22
    3-pentanone 0.42
    furfural 5.16
    n-dodecane 0.01
    diethylene glycol 5.38
    diisopropyl ether 0.03
    tert-amyl alcohol 0.14
    acetylacetone 0.91
    n-hexadecane 0.01
    acetophenone 0.47
    methyl propionate 0.75
    isopentyl acetate 0.1
    trichloroethylene 0.82
    n-nonanol 0.16
    cyclohexanol 0.26
    benzyl alcohol 0.56
    2-ethylhexanol 0.09
    isooctanol 0.13
    dipropyl ether 0.19
    1,2-dichlorobenzene 0.14
    ethyl lactate 0.6
    propylene carbonate 0.89
    n-methylformamide 7.46
    2-pentanol 0.12
    n-pentane 0.02
    1-propoxy-2-propanol 1.15
    1-methoxy-2-propyl acetate 0.63
    2-(2-methoxypropoxy) propanol 1.59
    mesitylene 0.08
    ε-caprolactone 1.24
    p-cymene 0.05
    epichlorohydrin 2.45
    1,1,1-trichloroethane 0.09
    2-aminoethanol 4.9
    morpholine-4-carbaldehyde 12.75
    sulfolane 13.64
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 0.57
    n-hexyl acetate 0.25
    isooctane 0.0
    2-(2-butoxyethoxy)ethanol 2.68
    sec-butyl acetate 0.09
    tert-butyl acetate 0.16
    decalin 0.01
    glycerin 14.67
    diglyme 4.43
    acrylic acid 2.92
    isopropyl myristate 0.06
    n-butyric acid 0.84
    acetyl acetate 0.26
    di(2-ethylhexyl) phthalate 0.21
    ethyl propionate 0.23
    nitromethane 6.2
    1,2-diethoxyethane 0.43
    benzonitrile 0.2
    trioctyl phosphate 0.13
    1-bromopropane 0.13
    gamma-valerolactone 9.56
    n-decanol 0.09
    triethyl phosphate 0.17
    4-methyl-2-pentanol 0.07
    propionitrile 0.2
    vinylene carbonate 1.18
    1,1,2-trichlorotrifluoroethane 7.84
    DMS 0.38
    cumene 0.06
    2-octanol 0.09
    2-hexanone 0.26
    octyl acetate 0.12
    limonene 0.07
    1,2-dimethoxyethane 2.45
    ethyl orthosilicate 0.16
    tributyl phosphate 0.12
    diacetone alcohol 0.77
    N,N-dimethylaniline 0.36
    acrylonitrile 0.54
    aniline 0.38
    1,3-propanediol 2.45
    bromobenzene 0.1
    dibromomethane 0.26
    1,1,2,2-tetrachloroethane 0.59
    2-methyl-cyclohexyl acetate 0.18
    tetrabutyl urea 0.31
    diisobutyl methanol 0.04
    2-phenylethanol 0.32
    styrene 0.09
    dioctyl adipate 0.19
    dimethyl sulfate 3.64
    ethyl butyrate 0.17
    methyl lactate 2.59
    butyl lactate 0.66
    diethyl carbonate 0.1
    propanediol butyl ether 2.76
    triethyl orthoformate 0.21
    p-tert-butyltoluene 0.05
    methyl 4-tert-butylbenzoate 0.93
    morpholine 2.2
    tert-butylamine 0.04
    n-dodecanol 0.05
    dimethoxymethane 5.65
    ethylene carbonate 0.64
    cyrene 5.36
    2-ethoxyethyl acetate 0.6
    2-ethylhexyl acetate 0.08
    1,2,4-trichlorobenzene 0.18
    4-methylpyridine 0.6
    dibutyl ether 0.09
    2,6-dimethyl-4-heptanol 0.04
    DEF 1.26
    dimethyl isosorbide 3.22
    tetrachloroethylene 0.55
    eugenol 1.26
    triacetin 0.65
    span 80 1.52
    1,4-butanediol 0.95
    1,1-dichloroethane 0.1
    2-methyl-1-pentanol 0.18
    methyl formate 4.85
    2-methyl-1-butanol 0.24
    n-decane 0.01
    butyronitrile 0.14
    3,7-dimethyl-1-octanol 0.08
    1-chlorooctane 0.05
    1-chlorotetradecane 0.01
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.01
    cyclooctane 0.01
    cyclopentanol 0.4
    tetrahydropyran 0.46
    tert-amyl methyl ether 0.13
    2,5,8-trioxanonane 3.16
    1-hexene 0.06
    2-isopropoxyethanol 1.02
    2,2,2-trifluoroethanol 2.67
    methyl butyrate 0.33

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction