Edetate Sodium
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Identifiers
Molecular formula
C10H12N2Na4O8SMILES
C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Na+].[Na+]
Safety labels
Corrosive
Irritant -
Odor profile
Fragrance Odorless 65.17% Sweet 38.53% Savory 25.02% Fishy 20.26% Alcoholic 17.69% Oily 14.69% Clean 14.2% Meaty 13.8% Milky 13.63% Cooling 13.55% Flavor Odorless 58.79% Bitter 39.77% Bland 30.93% Mild 28.59% Very mild 23.2% Sweet-like 21.29% Yeast 20.44% Nitrile 18.93% Bread crust 18.92% Roasted peanuts 18.58% Odor impact est.
Low -
Properties
pKa est.
-2.51 (strong acid)Molecular weight
380.17 g/molMelting point expt.
- 300 °C (decomposes)
Flash point
- 261.68 ˚C est.
Solubility expt.
- Slightly soluble in ethanol
- Less soluble in alcohol than the potassium salt
- Freely soluble in water
- In water, 500 g/L at 20 °C
- Solubility in water, g/100ml at 20 °C: 100-110
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Synonyms
- Sodium edetate
- Edetate sodium
- EDTA tetrasodium
- EDTA sodium
- Sodium EDTA
- Calsol
- EDTA tetrasodium salt
- Versene 100
- Endrate tetrasodium
- Sequestrene
- EDTA, tetrasodium
- Tetrine
- Syntes 12A
- Na4EDTA
- Trilon B
- Ergon
- Versene powder
- Versene 220
- Aquamoline BC
- Nervanaid B
- Nullapon B
- Kutrilon CS
- Natrium aedeticum
- Clewat T
- Tetrasodium ethylenediaminetetraacetate
- Celon H
- Ergon B
- Celon IS
- Questex 4
- Sequestrene Na 4
- Distol 8
- Hamp-ene Na4
- Nervanaid B liquid
- Nullapon BFC Xonc
- Perma kleer 100
- Tetrasodium salt of EDTA
- Versene FE 3
- Nullapon BF-12
- Nullapon BF-78
- Warkeelate PS-42
- Warkeelate PS-43
- Clewat S 2
- Nullapon BFC Liquid
- Cheelox BF-12
- Cheelox BF-13
- Cheelox BF-78
- Cheelox BR-33
- Chelest 400
- Kemplex 100
- Nervanaid
- Nullapo
- Sodium (edetate de)
- Chelon 100
- Perma kleer tetra CP
- Caswell No. 846
- Hamp-ene 100S
- Hamp-ene 215
- Hamp-ene 220
- Tetrasodium salt EDTA
- Nullapon BFC Xonc Beads
- Perma kleer 50 crystals
- Versene powder tetra sodium
- SODIUM ETHYLENEDIAMINETETRAACETATE
- CCRIS 6797
- Edetate
- HSDB 5003
- edetate tetrasodium
- EINECS 200-573-9
- Tetrasodium ethylenediaminetetracetate
- Sodium ethylenediaminetetraacetic acid
- UNII-MP1J8420LU
- EPA Pesticide Chemical Code 039107
- MP1J8420LU
- AI3-17182
- Ethylene diamine tetraacetic acid sodium salt
- Sodium salt of ethylenediaminetetraacetic acid
- Tetranatrium ethylendiamintetraacetat
- Ethylenediaminetetraacetic acid, tetrasodium salt
- Tetrasodium salt of ethylenediaminetetracetic acid
- N,N'-Ethylenediaminediacetic acid tetrasodium salt
- Tetrasodium ethylene diamine tetraacetate
- EC 200-573-9
- N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine) tetrasodium salt
- Cheladrate
- Disodium versene
- Acetic acid, (ethylenedinitrilo)tetra-, tetrasodium salt
- Kiresuto B
- Metaquest B
- Chelaplex III
- Chelest B
- Diso-Tate
- Komplexon III
- Chelaton III
- Clewat N
- Versene NA
- Chelaton 3
- Disodium versenate
- Edathamil disodium
- Trilon BD
- Triplex III
- Versene Na2
- Zonon D
- Dotite 2NA
- Selekton B 2
- Disodium sequestrene
- Disodium tetracemate
- Mavacid ED 4
- Versonol 120
- Chelest 200
- Sequestrene sodium 2
- Veresene disodium salt
- EDETATE SODIUM (II)
- EDETATE SODIUM [II]
- Disodium salt of EDTA
- E.D.T.A. disodique
- Acetic acid, (ethylenedinitrilo)tetra-, sodium salt
- Perma Kleer Di Crystals
- Edetic acid disodium salt
- UNII-8NLQ36F6MM
- TETRASODIUM EDETATE (MART.)
- TETRASODIUM EDETATE [MART.]
- CCRIS 3658
- Dinatrium ethylendiamintetraacetat
- HSDB 8013
- NSC 2760
- EINECS 205-358-3
- Perma kleer 50 crystals disodium salt
- 64-02-8
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Applications
Disodium edetate (edetate sodium) is a versatile chelating and sequestering agent widely used to bind trace metal ions and improve formulation stability across multiple industries. In cosmetics and personal care, it functions as a chelating agent to stabilize formulations and extend product shelf life. In household and industrial cleaners, it helps soften hard water and enhances cleaning efficiency by sequestering metal ions. In food processing, it is used as a sequestrant to prevent oxidation, preserve color, and improve product uniformity. In pharmaceuticals and clinical settings, it is used as an anticoagulant in blood collection tubes and as a stabilizing additive in certain formulations. In plastics and polymers, it serves as a processing aid to control metal ion activity and prevent degradation. In coatings and inks, it stabilizes pigment dispersions and prevents metal-catalyzed oxidation.
gpt-5-nano
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Solubility @25˚C
Solvent Solubility (g/L) ethanol 0.88 methanol 4.29 isopropanol 0.17 water 1.22 ethyl acetate 0.2 n-propanol 0.39 acetone 0.79 n-butanol 0.17 acetonitrile 0.27 DMF 37.0 toluene 0.1 isobutanol 0.15 1,4-dioxane 0.11 methyl acetate 0.43 THF 0.84 2-butanone 0.66 n-pentanol 0.06 sec-butanol 0.16 n-hexane 0.01 ethylene glycol 1.41 NMP 65.1 cyclohexane 0.01 DMSO 55.18 n-butyl acetate 0.22 n-octanol 0.04 chloroform 0.36 n-propyl acetate 0.12 acetic acid 3.01 dichloromethane 0.77 cyclohexanone 0.9 propylene glycol 1.16 isopropyl acetate 0.09 DMAc 30.83 2-ethoxyethanol 0.71 isopentanol 0.08 n-heptane 0.01 ethyl formate 0.67 1,2-dichloroethane 0.49 n-hexanol 0.07 2-methoxyethanol 4.21 isobutyl acetate 0.03 tetrachloromethane 0.07 n-pentyl acetate 0.07 transcutol 1.49 n-heptanol 0.05 ethylbenzene 0.05 MIBK 0.11 2-propoxyethanol 0.89 tert-butanol 0.13 MTBE 0.06 2-butoxyethanol 0.33 propionic acid 1.39 o-xylene 0.16 formic acid 14.91 diethyl ether 0.07 m-xylene 0.08 p-xylene 0.06 chlorobenzene 0.1 dimethyl carbonate 0.93 n-octane 0.0 formamide 20.93 cyclopentanone 2.24 2-pentanone 0.32 anisole 0.12 cyclopentyl methyl ether 0.24 gamma-butyrolactone 4.17 1-methoxy-2-propanol 1.76 pyridine 0.84 3-pentanone 0.44 furfural 6.75 n-dodecane 0.0 diethylene glycol 1.42 diisopropyl ether 0.01 tert-amyl alcohol 0.17 acetylacetone 0.56 n-hexadecane 0.0 acetophenone 0.48 methyl propionate 0.81 isopentyl acetate 0.13 trichloroethylene 1.17 n-nonanol 0.04 cyclohexanol 0.1 benzyl alcohol 0.24 2-ethylhexanol 0.05 isooctanol 0.03 dipropyl ether 0.12 1,2-dichlorobenzene 0.17 ethyl lactate 0.5 propylene carbonate 1.2 n-methylformamide 13.44 2-pentanol 0.06 n-pentane 0.01 1-propoxy-2-propanol 0.63 1-methoxy-2-propyl acetate 0.62 2-(2-methoxypropoxy) propanol 0.92 mesitylene 0.05 ε-caprolactone 0.92 p-cymene 0.08 epichlorohydrin 1.57 1,1,1-trichloroethane 0.14 2-aminoethanol 1.94 morpholine-4-carbaldehyde 9.8 sulfolane 27.29 2,2,4-trimethylpentane 0.01 2-methyltetrahydrofuran 0.23 n-hexyl acetate 0.09 isooctane 0.0 2-(2-butoxyethoxy)ethanol 0.56 sec-butyl acetate 0.05 tert-butyl acetate 0.12 decalin 0.01 glycerin 4.55 diglyme 1.37 acrylic acid 2.93 isopropyl myristate 0.03 n-butyric acid 0.7 acetyl acetate 0.14 di(2-ethylhexyl) phthalate 0.13 ethyl propionate 0.19 nitromethane 6.37 1,2-diethoxyethane 0.1 benzonitrile 0.17 trioctyl phosphate 0.08 1-bromopropane 0.13 gamma-valerolactone 4.9 n-decanol 0.03 triethyl phosphate 0.36 4-methyl-2-pentanol 0.02 propionitrile 0.23 vinylene carbonate 1.41 1,1,2-trichlorotrifluoroethane 6.51 DMS 0.34 cumene 0.04 2-octanol 0.02 2-hexanone 0.13 octyl acetate 0.05 limonene 0.11 1,2-dimethoxyethane 0.91 ethyl orthosilicate 0.23 tributyl phosphate 0.13 diacetone alcohol 0.54 N,N-dimethylaniline 0.31 acrylonitrile 0.83 aniline 0.29 1,3-propanediol 0.98 bromobenzene 0.08 dibromomethane 0.35 1,1,2,2-tetrachloroethane 0.84 2-methyl-cyclohexyl acetate 0.18 tetrabutyl urea 0.36 diisobutyl methanol 0.04 2-phenylethanol 0.18 styrene 0.06 dioctyl adipate 0.11 dimethyl sulfate 6.86 ethyl butyrate 0.26 methyl lactate 2.43 butyl lactate 0.33 diethyl carbonate 0.21 propanediol butyl ether 0.43 triethyl orthoformate 0.23 p-tert-butyltoluene 0.07 methyl 4-tert-butylbenzoate 0.56 morpholine 0.45 tert-butylamine 0.06 n-dodecanol 0.02 dimethoxymethane 2.3 ethylene carbonate 0.57 cyrene 1.89 2-ethoxyethyl acetate 0.17 2-ethylhexyl acetate 0.11 1,2,4-trichlorobenzene 0.26 4-methylpyridine 0.64 dibutyl ether 0.03 2,6-dimethyl-4-heptanol 0.04 DEF 2.02 dimethyl isosorbide 1.92 tetrachloroethylene 0.71 eugenol 0.56 triacetin 0.34 span 80 0.41 1,4-butanediol 0.21 1,1-dichloroethane 0.15 2-methyl-1-pentanol 0.04 methyl formate 5.99 2-methyl-1-butanol 0.12 n-decane 0.0 butyronitrile 0.12 3,7-dimethyl-1-octanol 0.04 1-chlorooctane 0.02 1-chlorotetradecane 0.01 n-nonane 0.0 undecane 0.0 tert-butylcyclohexane 0.01 cyclooctane 0.0 cyclopentanol 0.21 tetrahydropyran 0.09 tert-amyl methyl ether 0.11 2,5,8-trioxanonane 1.16 1-hexene 0.03 2-isopropoxyethanol 0.18 2,2,2-trifluoroethanol 2.19 methyl butyrate 0.34 Scent© AI
| Maximum acceptable concentrations in the finished product (%) | |||
|---|---|---|---|
|
Category 1
Products applied to the lips
|
No restriction |
Category 7A
Rinse-off products applied to the hair with some hand contact
|
No restriction |
|
Category 2
Products applied to the axillae
|
No restriction |
Category 7B
Leave-on products applied to the hair with some hand contact
|
No restriction |
|
Category 3
Products applied to the face/body using fingertips
|
No restriction |
Category 8
Products with significant anogenital exposure
|
No restriction |
|
Category 4
Products related to fine fragrance
|
No restriction |
Category 9
Products with body and hand exposure, primarily rinse off
|
No restriction |
|
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
|
No restriction |
Category 10A
Household care products with mostly hand contact
|
No restriction |
|
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
|
No restriction |
Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
|
No restriction |
|
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
|
No restriction |
Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
|
No restriction |
|
Category 5D
Baby Creams, baby Oils and baby talc
|
No restriction |
Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
|
No restriction |
|
Category 6
Products with oral and lip exposure
|
No restriction |
Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
|
No restriction |