DL-Glutamic acid

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  • Identifiers

    CAS number
    617-65-2

    Molecular formula
    C5H9NO4

    SMILES
    C(CC(=O)O)C(C(=O)O)N

  • Odor profile

    Fragrance
    Odorless 72.25%
    Savory 34.05%
    Meaty 29.54%
    Sweet 26.6%
    Sour 23.91%
    Milky 19.79%
    Cooked 19.63%
    Sulfurous 18.11%
    Buttery 17.73%
    Cheesy 16.66%

     

    Flavor
    Odorless 75.68%
    Mild 37.48%
    Sour 32.48%
    Very mild 30.83%
    Bland 26.88%
    Yeast 26.41%
    Faint 24.74%
    Acidic 23.8%
    Sweet-like 22.28%
    Soy 20.24%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -3.7

    pKa est.
    5.34 (weak acid)

    Molecular weight
    147.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    346°C

    Flash point

    • 194.27 ˚C est.

  • Synonyms

    • DL-Glutamic acid
    • 617-65-2
    • 2-aminopentanedioic acid
    • Glutamic acid, DL-
    • Glutamic acid DL-form
    • Glutaminsaeure
    • H-DL-Glu-OH
    • NSC 9967
    • glutamate
    • H-DL-Glu-OH.H2O
    • NSC 206301
    • D-Glutamicacid
    • EINECS 210-522-2
    • MFCD00063113
    • BRN 1723799
    • 61LJO5I15S
    • NSC-9967
    • 2-Aminoglutaric acid
    • .alpha.-Aminoglutaric acid
    • L-Glutamic-2-13C Acid
    • NSC-206301
    • DL-Glutamic-2-13C acid
    • DL-Glutamic acid-3,3-d2
    • 53931-70-7
    • DTXSID0046987
    • 4-04-00-03028 (Beilstein Handbook Reference)
    • GLUTAMIC ACID DL-FORM [MI]
    • NSC620337
    • L-2-Aminoglutaric acid
    • DL-Glu
    • GLUTAMIC ACID, DL-(II)
    • GLUTAMIC ACID, DL-[II]
    • (+-)-Glutamic acid
    • Glutamate, L-
    • glutamic acid-2,3,3,4,4-d5
    • Glutamic acid (VAN)
    • .alpha.-Glutamic acid
    • 25513-46-6
    • Glutamic acid (USAN)
    • Polyglutamic acid(PGA)
    • 49717-32-0
    • Glutaminic acid (VAN)
    • 2-Amino-pentanedioic acid
    • L(+)-Monosodium glutamate monohydrate
    • Glutamic Acid [USAN:INN]
    • alpha-Aminoglutaric acid (VAN)
    • glutaminsaure
    • UNII-61LJO5I15S
    • NSC143503
    • DL-Glutamate
    • 4-Amino-1,5-pentanedioic acid
    • Glutamic acid, dl
    • D,L-glutamic acid
    • DL-Glutaminic acid
    • 2IT
    • L-GLUTAMIC ACID (5-13C)
    • Glutamic acid DLform
    • (+/-)-glutamic acid
    • Glu146
    • Pentanedioic acid, (S)-
    • bmse000037
    • bmse000913
    • bmse001013
    • WLN: QVYZ2VQ -L
    • SCHEMBL2201
    • (.+/-.)-Glutamic acid
    • NCIOpen2_000764
    • CHEMBL276389
    • DTXCID8026987
    • CHEBI:18237
    • CHEBI:53373
    • NSC9967
    • GLUTAMIC ACID, DL- [II]
    • FCA44355
    • L-Glutamic acid, non animal origin
    • NSC77686
    • 2-aminopentanedioic acidglutamic acid
    • AC7831
    • BDBM50002371
    • NSC206301
    • PDSP1_000621
    • PDSP2_000618
    • STK017280
    • 2-azaniumyl-5-hydroxy-5-oxopentanoate
    • AKOS000118798
    • AKOS016050534
    • CS-W022635
    • FG39655
    • HY-W041895
    • NSC-620337
    • GLUTAMIC ACID, L-, [5-14C]
    • NCGC00015470-02
    • AC-24034
    • AS-13496
    • SY007089
    • SY008517
    • L(+)-Glutamic acid; 2-Aminoglutaric acid
    • DB-055206
    • G0058
    • NS00008008
    • EN300-18047
    • C00302
    • D04341
    • AB00443951-09
    • (R)-2-aminopentanedioic acid;D(-)-Glutamic acid
    • L001165
    • Q181136
    • Q27145702
    • Z57127545
    • 96C32356-219C-4821-AF0E-30FCBFA1A321

  • Applications

    DL-Glutamic acid (CAS 617-65-2) is used as a feed additive to supply amino acids in animal nutrition; it serves as a starting material for flavor-related derivatives in food processing, including precursors to glutamates that contribute umami; it provides a polymerizable unit for polyglutamic acid-based polymers and derivatives used as thickeners and biodegradable materials in cosmetics and industrial applications; it is employed in pharmaceutical manufacturing as an amino acid supplement in formulations and in parenteral nutrition; and it functions as a chemical intermediary for the synthesis of amino-acid-derived specialty chemicals in various industrial processes.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 2.94
    methanol 2.55
    isopropanol 1.57
    water 12.66
    ethyl acetate 0.95
    n-propanol 1.24
    acetone 3.11
    n-butanol 1.41
    acetonitrile 0.83
    DMF 82.65
    toluene 0.42
    isobutanol 0.92
    1,4-dioxane 12.91
    methyl acetate 0.64
    THF 5.57
    2-butanone 1.21
    n-pentanol 0.8
    sec-butanol 1.01
    n-hexane 0.64
    ethylene glycol 11.55
    NMP 83.1
    cyclohexane 0.82
    DMSO 67.08
    n-butyl acetate 0.65
    n-octanol 1.07
    chloroform 0.1
    n-propyl acetate 0.44
    acetic acid 7.03
    dichloromethane 0.3
    cyclohexanone 4.46
    propylene glycol 6.22
    isopropyl acetate 0.81
    DMAc 53.67
    2-ethoxyethanol 7.12
    isopentanol 1.23
    n-heptane 0.9
    ethyl formate 1.38
    1,2-dichloroethane 0.55
    n-hexanol 1.19
    2-methoxyethanol 19.21
    isobutyl acetate 0.19
    tetrachloromethane 0.07
    n-pentyl acetate 0.75
    transcutol 12.69
    n-heptanol 1.47
    ethylbenzene 0.4
    MIBK 1.0
    2-propoxyethanol 6.76
    tert-butanol 1.98
    MTBE 0.97
    2-butoxyethanol 5.89
    propionic acid 2.15
    o-xylene 1.04
    formic acid 29.22
    diethyl ether 1.38
    m-xylene 0.59
    p-xylene 0.57
    chlorobenzene 0.16
    dimethyl carbonate 1.96
    n-octane 0.39
    formamide 23.89
    cyclopentanone 4.81
    2-pentanone 1.64
    anisole 0.8
    cyclopentyl methyl ether 3.07
    gamma-butyrolactone 6.92
    1-methoxy-2-propanol 11.02
    pyridine 2.32
    3-pentanone 1.48
    furfural 9.69
    n-dodecane 0.18
    diethylene glycol 14.48
    diisopropyl ether 0.61
    tert-amyl alcohol 1.48
    acetylacetone 3.39
    n-hexadecane 0.2
    acetophenone 1.32
    methyl propionate 1.63
    isopentyl acetate 0.55
    trichloroethylene 0.38
    n-nonanol 1.15
    cyclohexanol 2.36
    benzyl alcohol 1.18
    2-ethylhexanol 0.85
    isooctanol 1.05
    dipropyl ether 1.67
    1,2-dichlorobenzene 0.26
    ethyl lactate 1.29
    propylene carbonate 2.52
    n-methylformamide 12.58
    2-pentanol 1.01
    n-pentane 0.45
    1-propoxy-2-propanol 3.93
    1-methoxy-2-propyl acetate 2.02
    2-(2-methoxypropoxy) propanol 6.18
    mesitylene 0.65
    ε-caprolactone 4.51
    p-cymene 0.58
    epichlorohydrin 3.19
    1,1,1-trichloroethane 0.09
    2-aminoethanol 8.69
    morpholine-4-carbaldehyde 60.75
    sulfolane 24.53
    2,2,4-trimethylpentane 0.16
    2-methyltetrahydrofuran 2.89
    n-hexyl acetate 1.01
    isooctane 0.1
    2-(2-butoxyethoxy)ethanol 9.33
    sec-butyl acetate 0.32
    tert-butyl acetate 1.03
    decalin 0.32
    glycerin 29.04
    diglyme 14.25
    acrylic acid 3.98
    isopropyl myristate 0.53
    n-butyric acid 2.25
    acetyl acetate 0.73
    di(2-ethylhexyl) phthalate 1.08
    ethyl propionate 0.72
    nitromethane 8.28
    1,2-diethoxyethane 1.95
    benzonitrile 0.64
    trioctyl phosphate 0.9
    1-bromopropane 0.24
    gamma-valerolactone 20.36
    n-decanol 0.97
    triethyl phosphate 0.84
    4-methyl-2-pentanol 0.67
    propionitrile 0.41
    vinylene carbonate 2.24
    1,1,2-trichlorotrifluoroethane 6.56
    DMS 1.29
    cumene 0.44
    2-octanol 0.83
    2-hexanone 0.65
    octyl acetate 0.81
    limonene 0.88
    1,2-dimethoxyethane 8.84
    ethyl orthosilicate 0.84
    tributyl phosphate 0.68
    diacetone alcohol 3.61
    N,N-dimethylaniline 1.81
    acrylonitrile 0.89
    aniline 1.04
    1,3-propanediol 8.5
    bromobenzene 0.12
    dibromomethane 0.19
    1,1,2,2-tetrachloroethane 0.56
    2-methyl-cyclohexyl acetate 0.72
    tetrabutyl urea 2.14
    diisobutyl methanol 0.7
    2-phenylethanol 1.18
    styrene 0.3
    dioctyl adipate 0.92
    dimethyl sulfate 7.35
    ethyl butyrate 0.8
    methyl lactate 5.26
    butyl lactate 1.83
    diethyl carbonate 0.48
    propanediol butyl ether 6.49
    triethyl orthoformate 1.01
    p-tert-butyltoluene 0.55
    methyl 4-tert-butylbenzoate 3.42
    morpholine 12.46
    tert-butylamine 0.9
    n-dodecanol 0.79
    dimethoxymethane 12.1
    ethylene carbonate 1.78
    cyrene 10.13
    2-ethoxyethyl acetate 1.53
    2-ethylhexyl acetate 0.49
    1,2,4-trichlorobenzene 0.35
    4-methylpyridine 1.87
    dibutyl ether 0.82
    2,6-dimethyl-4-heptanol 0.7
    DEF 9.59
    dimethyl isosorbide 7.52
    tetrachloroethylene 0.5
    eugenol 4.02
    triacetin 1.89
    span 80 6.03
    1,4-butanediol 3.22
    1,1-dichloroethane 0.14
    2-methyl-1-pentanol 0.72
    methyl formate 6.35
    2-methyl-1-butanol 1.12
    n-decane 0.3
    butyronitrile 0.59
    3,7-dimethyl-1-octanol 0.68
    1-chlorooctane 0.38
    1-chlorotetradecane 0.23
    n-nonane 0.33
    undecane 0.22
    tert-butylcyclohexane 0.17
    cyclooctane 0.58
    cyclopentanol 2.54
    tetrahydropyran 2.74
    tert-amyl methyl ether 1.29
    2,5,8-trioxanonane 13.26
    1-hexene 0.59
    2-isopropoxyethanol 3.06
    2,2,2-trifluoroethanol 4.17
    methyl butyrate 1.01

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction